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Volumn 3 SEP, Issue , 2013, Pages

Cord blood transplantation: Can we make it better?

Author keywords

Delayed engraftment; Double umbilical cord transplant; Ex vivo expansion; Mesenchymal stem cells; Reduced intensity conditioning; Umbilical cord blood transplantation

Indexed keywords

BUSULFAN; CD45 ANTIGEN; COPPER; CYCLOPHOSPHAMIDE; CYCLOSPORIN; FLUDARABINE; MELPHALAN; METHOTREXATE; METHYLPREDNISOLONE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PREDNISONE; TACROLIMUS; THYMOCYTE ANTIBODY;

EID: 84891140189     PISSN: None     EISSN: 2234943X     Source Type: Journal    
DOI: 10.3389/fonc.2013.00238     Document Type: Review
Times cited : (23)

References (91)
  • 1
    • 0024396816 scopus 로고
    • Hematopoietic reconstitution in a patient with Fanconi's anemia by means of umbilical-cord blood from an HLA-matched sibling
    • doi:10.1056/NEJM198910263211707
    • Gluckman E, Broxmeyer HA, Auerbach AD, Friedman HS, Douglas GW, Devergie A, et al. Hematopoietic reconstitution in a patient with Fanconi's anemia by means of umbilical-cord blood from an HLA-matched sibling. N Engl J Med (1989) 321:1174-8. doi:10.1056/NEJM198910263211707
    • (1989) N Engl J Med , vol.321 , pp. 1174-1178
    • Gluckman, E.1    Broxmeyer, H.A.2    Auerbach, A.D.3    Friedman, H.S.4    Douglas, G.W.5    Devergie, A.6
  • 2
    • 0027470021 scopus 로고
    • Stored placental blood for unrelated bone marrow reconstitution
    • Rubinstein P, Rosenfield RE, Adamson JW, Stevens CE. Stored placental blood for unrelated bone marrow reconstitution. Blood (1993) 81:1679-90.
    • (1993) Blood , vol.81 , pp. 1679-1690
    • Rubinstein, P.1    Rosenfield, R.E.2    Adamson, J.W.3    Stevens, C.E.4
  • 3
    • 0028785797 scopus 로고
    • Processing and cryopreservation of placental/umbilical cord blood for unrelated bone marrow reconstitution
    • doi:10.1073/pnas.92.22.10119
    • Rubinstein P, Dobrila L, Rosenfield RE, Adamson JW, Migliaccio G, Migliaccio AR, et al. Processing and cryopreservation of placental/umbilical cord blood for unrelated bone marrow reconstitution. Proc Natl Acad Sci U S A (1995) 92:10119-22. doi:10.1073/pnas.92.22.10119
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 10119-10122
    • Rubinstein, P.1    Dobrila, L.2    Rosenfield, R.E.3    Adamson, J.W.4    Migliaccio, G.5    Migliaccio, A.R.6
  • 4
    • 0026506022 scopus 로고
    • Growth characteristics and expansion of human umbilical cord blood and estimation of its potential for transplantation in adults
    • doi:10.1073/pnas.89.9.4109
    • Broxmeyer HE, Hangoc G, Cooper S, Ribeiro RC, Graves V, Yoder M, et al. Growth characteristics and expansion of human umbilical cord blood and estimation of its potential for transplantation in adults. Proc Natl Acad Sci U S A (1992) 89:4109-13. doi:10.1073/pnas.89.9.4109
    • (1992) Proc Natl Acad Sci U S A , vol.89 , pp. 4109-4113
    • Broxmeyer, H.E.1    Hangoc, G.2    Cooper, S.3    Ribeiro, R.C.4    Graves, V.5    Yoder, M.6
  • 5
    • 77957752908 scopus 로고    scopus 로고
    • Availability of cord blood extends allogeneic hematopoietic stem cell transplant access to racial and ethnic minorities
    • doi:10.1016/j.bbmt.2010.08.011
    • Barker JN, Byam CE, Kernan NA, Lee SS, Hawke RM, Doshi KA, et al. Availability of cord blood extends allogeneic hematopoietic stem cell transplant access to racial and ethnic minorities. Biol Blood Marrow Transplant (2010) 16(11):1541-8. doi:10.1016/j.bbmt.2010.08.011
    • (2010) Biol Blood Marrow Transplant , vol.16 , Issue.11 , pp. 1541-1548
    • Barker, J.N.1    Byam, C.E.2    Kernan, N.A.3    Lee, S.S.4    Hawke, R.M.5    Doshi, K.A.6
  • 6
    • 0029036129 scopus 로고
    • Allogeneic sibling umbilical-cord-blood transplantation in children with malignant and non-malignant disease
    • doi:10.1016/S0140-6736(95)91268-1
    • Wagner JE, Kernan NA, Steinbuch M, Broxmeyer HE, Gluckman E. Allogeneic sibling umbilical-cord-blood transplantation in children with malignant and non-malignant disease. Lancet (1995) 346:214-9. doi:10.1016/S0140-6736(95)91268-1
    • (1995) Lancet , vol.346 , pp. 214-219
    • Wagner, J.E.1    Kernan, N.A.2    Steinbuch, M.3    Broxmeyer, H.E.4    Gluckman, E.5
  • 7
    • 0029742950 scopus 로고    scopus 로고
    • Successful transplantation of HLA-matched and HLA-mismatched umbilical cord blood from unrelated donors: analysis of engraftment and acute graft-versus-host disease
    • Wagner JE, Rosenthal J, Sweetman R, Shu XO, Davies SM, Ramsay NK, et al. Successful transplantation of HLA-matched and HLA-mismatched umbilical cord blood from unrelated donors: analysis of engraftment and acute graft-versus-host disease. Blood (1996) 88(3):795-802.
    • (1996) Blood , vol.88 , Issue.3 , pp. 795-802
    • Wagner, J.E.1    Rosenthal, J.2    Sweetman, R.3    Shu, X.O.4    Davies, S.M.5    Ramsay, N.K.6
  • 8
    • 0035874535 scopus 로고    scopus 로고
    • Survival after transplantation of unrelated donor umbilical cord blood is comparable to that of human leukocyte antigen-matched unrelated donor bone marrow: results of a matched-pair analysis
    • doi:10.1182/blood.V97.10.2957
    • Barker JN, Davies SM, DeFor T, Ramsay NK, Weisdorf DJ, Wagner JE. Survival after transplantation of unrelated donor umbilical cord blood is comparable to that of human leukocyte antigen-matched unrelated donor bone marrow: results of a matched-pair analysis. Blood (2001) 97(10):2957-61. doi:10.1182/blood.V97.10.2957
    • (2001) Blood , vol.97 , Issue.10 , pp. 2957-2961
    • Barker, J.N.1    Davies, S.M.2    DeFor, T.3    Ramsay, N.K.4    Weisdorf, D.J.5    Wagner, J.E.6
  • 9
    • 0032569779 scopus 로고    scopus 로고
    • Outcomes among 562 recipients of placental-blood transplants from unrelated donors
    • doi:10.1056/NEJM199811263392201
    • Rubinstein P, Carrier C, Scaradavou A, Kurtzberg J, Adamson J, Migliaccio AR, et al. Outcomes among 562 recipients of placental-blood transplants from unrelated donors. N Engl J Med (1997) 339:1565-77. doi:10.1056/NEJM199811263392201
    • (1997) N Engl J Med , vol.339 , pp. 1565-1577
    • Rubinstein, P.1    Carrier, C.2    Scaradavou, A.3    Kurtzberg, J.4    Adamson, J.5    Migliaccio, A.R.6
  • 10
    • 0030854656 scopus 로고    scopus 로고
    • Outcome of cord-blood transplantation from related and unrelated donors. Eurocord transplant group and the European blood and marrow transplantation group
    • doi:10.1056/NEJM199708073370602
    • Gluckman E, Rocha V, Boyer-Chammard A, Locatelli F, Arcese W, Pasquini R, et al. Outcome of cord-blood transplantation from related and unrelated donors. Eurocord transplant group and the European blood and marrow transplantation group. N Engl J Med (1997) 337:373-81. doi:10.1056/NEJM199708073370602
    • (1997) N Engl J Med , vol.337 , pp. 373-381
    • Gluckman, E.1    Rocha, V.2    Boyer-Chammard, A.3    Locatelli, F.4    Arcese, W.5    Pasquini, R.6
  • 11
    • 0035874490 scopus 로고    scopus 로고
    • Comparison of outcomes of unrelated bone marrow and umbilical cord blood transplants in children with acute leukemia
    • doi:10.1182/blood.V97.10.2962
    • Rocha V, Cornish J, Sievers EL, Filipovich A, Locatelli F, Peters C, et al. Comparison of outcomes of unrelated bone marrow and umbilical cord blood transplants in children with acute leukemia. Blood (2001) 97(10):2962-71. doi:10.1182/blood.V97.10.2962
    • (2001) Blood , vol.97 , Issue.10 , pp. 2962-2971
    • Rocha, V.1    Cornish, J.2    Sievers, E.L.3    Filipovich, A.4    Locatelli, F.5    Peters, C.6
  • 12
    • 34249899377 scopus 로고    scopus 로고
    • Outcomes of transplantation of unrelated donor umbilical cord blood and bone marrow in children with acute leukaemia: a comparison study
    • doi:10.1016/S0140-6736(07)60915-5
    • Eapen M, Rubinstein P, Zhang MJ, Stevens C, Kurtzberg J, Scaradavou A, et al. Outcomes of transplantation of unrelated donor umbilical cord blood and bone marrow in children with acute leukaemia: a comparison study. Lancet (2007) 369(9577):1947-54. doi:10.1016/S0140-6736(07)60915-5
    • (2007) Lancet , vol.369 , Issue.9577 , pp. 1947-1954
    • Eapen, M.1    Rubinstein, P.2    Zhang, M.J.3    Stevens, C.4    Kurtzberg, J.5    Scaradavou, A.6
  • 13
    • 58149165364 scopus 로고    scopus 로고
    • Results of the cord blood transplantation study (COBLT): clinical outcomes of unrelated donor umbilical cord blood transplantation in pediatric patients with hematologic malignancies
    • doi:10.1182/blood-2007-06-098020
    • Kurtzberg J, Prasad VK, Carter SL, Wagner JE, Baxter-Lowe LA, Wall D, et al. Results of the cord blood transplantation study (COBLT): clinical outcomes of unrelated donor umbilical cord blood transplantation in pediatric patients with hematologic malignancies. Blood (2008) 112:4318-27. doi:10.1182/blood-2007-06-098020
    • (2008) Blood , vol.112 , pp. 4318-4327
    • Kurtzberg, J.1    Prasad, V.K.2    Carter, S.L.3    Wagner, J.E.4    Baxter-Lowe, L.A.5    Wall, D.6
  • 14
    • 0036721158 scopus 로고    scopus 로고
    • Transplantation of unrelated donor umbilical cord blood in 102 patients with malignant and nonmalignant diseases: influence of CD34 cell dose and HLA disparity on treatment-related mortality and survival
    • Wagner JE, Barker JN, DeFor TE, Baker KS, Blazar BR, Eide C, et al. Transplantation of unrelated donor umbilical cord blood in 102 patients with malignant and nonmalignant diseases: influence of CD34 cell dose and HLA disparity on treatment-related mortality and survival. Blood (2002) 100(5):1611-8.
    • (2002) Blood , vol.100 , Issue.5 , pp. 1611-1618
    • Wagner, J.E.1    Barker, J.N.2    DeFor, T.E.3    Baker, K.S.4    Blazar, B.R.5    Eide, C.6
  • 15
    • 0033152326 scopus 로고    scopus 로고
    • Factors associated with outcome after cord blood transplantation in children with acute leukemia. Eurocord-cord blood transplant group
    • Locatelli F, Rocha V, Chastang C, Arcese W, Michel G, Abecasis M, et al. Factors associated with outcome after cord blood transplantation in children with acute leukemia. Eurocord-cord blood transplant group. Blood (1999) 93:3662-71.
    • (1999) Blood , vol.93 , pp. 3662-3671
    • Locatelli, F.1    Rocha, V.2    Chastang, C.3    Arcese, W.4    Michel, G.5    Abecasis, M.6
  • 16
    • 7444221208 scopus 로고    scopus 로고
    • Cord blood transplantation for children with acute leukaemia: a Eurocord registry analysis
    • Gluckman E, Rocha V. Cord blood transplantation for children with acute leukaemia: a Eurocord registry analysis. Blood Cells Mol Dis (2004) 33:271-3.
    • (2004) Blood Cells Mol Dis , vol.33 , pp. 271-273
    • Gluckman, E.1    Rocha, V.2
  • 17
    • 0035859201 scopus 로고    scopus 로고
    • Hematopoietic engraftment and survival in adult recipients of umbilical-cord blood from unrelated donors
    • doi:10.1056/NEJM200106143442402
    • Laughlin MJ, Barker J, Bambach B, Koc ON, Rizzieri DA, Wagner JE, et al. Hematopoietic engraftment and survival in adult recipients of umbilical-cord blood from unrelated donors. N Engl J Med (2001) 344(24):1815-22. doi:10.1056/NEJM200106143442402
    • (2001) N Engl J Med , vol.344 , Issue.24 , pp. 1815-1822
    • Laughlin, M.J.1    Barker, J.2    Bambach, B.3    Koc, O.N.4    Rizzieri, D.A.5    Wagner, J.E.6
  • 18
    • 0035889124 scopus 로고    scopus 로고
    • Standardized, unrelated donor cord blood transplantation in adults with hematologic malignancies
    • doi:10.1182/blood.V98.8.2332
    • Sanz GF, Saavedra S, Planelles D, Senent L, Cervera J, Barragán E, et al. Standardized, unrelated donor cord blood transplantation in adults with hematologic malignancies. Blood (2001) 98:2332-8. doi:10.1182/blood.V98.8.2332
    • (2001) Blood , vol.98 , pp. 2332-2338
    • Sanz, G.F.1    Saavedra, S.2    Planelles, D.3    Senent, L.4    Cervera, J.5    Barragán, E.6
  • 19
    • 19944433869 scopus 로고    scopus 로고
    • Umbilical cord blood transplantation in adults: results of the prospective cord blood transplantation (COBLT)
    • doi:10.1016/j.bbmt.2004.11.020
    • Cornetta K, Laughlin M, Carter S, Wall D, Weinthal J, Delaney C, et al. Umbilical cord blood transplantation in adults: results of the prospective cord blood transplantation (COBLT). Biol Blood Marrow Transplant (2005) 11:149-60. doi:10.1016/j.bbmt.2004.11.020
    • (2005) Biol Blood Marrow Transplant , vol.11 , pp. 149-160
    • Cornetta, K.1    Laughlin, M.2    Carter, S.3    Wall, D.4    Weinthal, J.5    Delaney, C.6
  • 20
    • 8544279030 scopus 로고    scopus 로고
    • Single-institute comparative analysis of unrelated bone marrow transplantation and cord blood transplantation for adult patients with hematologic malignancies
    • doi:10.1182/blood-2004-03-1001
    • Takahashi S, Iseki T, Ooi J, Tomonari A, Takasugi K, Shimohakamada Y, et al. Single-institute comparative analysis of unrelated bone marrow transplantation and cord blood transplantation for adult patients with hematologic malignancies. Blood (2004) 104:3813-20. doi:10.1182/blood-2004-03-1001
    • (2004) Blood , vol.104 , pp. 3813-3820
    • Takahashi, S.1    Iseki, T.2    Ooi, J.3    Tomonari, A.4    Takasugi, K.5    Shimohakamada, Y.6
  • 21
    • 33846007695 scopus 로고    scopus 로고
    • Double unrelated reduced-intensity umbilical cord blood transplantation in adults
    • doi:10.1016/j.bbmt.2006.08.041
    • Ballen KK, Spitzer TR, Yeap BY, McAfee S, Dey BR, Attar E, et al. Double unrelated reduced-intensity umbilical cord blood transplantation in adults. Biol Blood Marrow Transplant (2007) 13(1):82-9. doi:10.1016/j.bbmt.2006.08.041
    • (2007) Biol Blood Marrow Transplant , vol.13 , Issue.1 , pp. 82-89
    • Ballen, K.K.1    Spitzer, T.R.2    Yeap, B.Y.3    McAfee, S.4    Dey, B.R.5    Attar, E.6
  • 22
    • 10744225349 scopus 로고    scopus 로고
    • Kinetics of myeloid and lymphocyte recovery and infectious complications after unrelated umbilical cord blood versus HLA-matched unrelated donor allogeneic transplantation in adults
    • doi:10.1046/j.1365-2141.2003.04792.x
    • Hamza NS, Lisgaris M, Yadavalli G, Nadeau L, Fox R, Fu P, et al. Kinetics of myeloid and lymphocyte recovery and infectious complications after unrelated umbilical cord blood versus HLA-matched unrelated donor allogeneic transplantation in adults. Br J Haematol (2004) 124:488-98. doi:10.1046/j.1365-2141.2003.04792.x
    • (2004) Br J Haematol , vol.124 , pp. 488-498
    • Hamza, N.S.1    Lisgaris, M.2    Yadavalli, G.3    Nadeau, L.4    Fox, R.5    Fu, P.6
  • 23
    • 9244219607 scopus 로고    scopus 로고
    • Transplants of umbilical cord blood or bone marrow from unrelated donors in adults with acute leukemia
    • doi:10.1056/NEJMoa041469
    • Rocha V, Labopin M, Sanz G, Arcese W, Schwerdtfeger R, Bosi A, et al. Transplants of umbilical cord blood or bone marrow from unrelated donors in adults with acute leukemia. N Engl J Med (2004) 351:2276-85. doi:10.1056/NEJMoa041469
    • (2004) N Engl J Med , vol.351 , pp. 2276-2285
    • Rocha, V.1    Labopin, M.2    Sanz, G.3    Arcese, W.4    Schwerdtfeger, R.5    Bosi, A.6
  • 24
    • 77954031042 scopus 로고    scopus 로고
    • Effect of graft source on unrelated donor haemopoietic stem-cell transplantation in adults with acute leukaemia: a retrospective analysis
    • doi:10.1016/S1470-2045(10)70127-3
    • Eapen M, Rocha V, Sanz G, Scaradavou A, Zhang MJ, Arcese W, et al. Effect of graft source on unrelated donor haemopoietic stem-cell transplantation in adults with acute leukaemia: a retrospective analysis. Lancet Oncol (2010) 11:653-60. doi:10.1016/S1470-2045(10)70127-3
    • (2010) Lancet Oncol , vol.11 , pp. 653-660
    • Eapen, M.1    Rocha, V.2    Sanz, G.3    Scaradavou, A.4    Zhang, M.J.5    Arcese, W.6
  • 25
    • 82555165881 scopus 로고    scopus 로고
    • Effect of donor-recipient HLA matching at HLA A, B, C, and DRB1 on outcomes after umbilical-cord blood transplantation for leukaemia and myelodysplastic syndrome: a retrospective analysis
    • doi:10.1016/S1470-2045(11)70260-1
    • Eapen M, Klein JP, Sanz GF, Spellman S, Ruggeri A, Anasetti C, et al. Effect of donor-recipient HLA matching at HLA A, B, C, and DRB1 on outcomes after umbilical-cord blood transplantation for leukaemia and myelodysplastic syndrome: a retrospective analysis. Lancet Oncol (2011) 12:1214-21. doi:10.1016/S1470-2045(11)70260-1
    • (2011) Lancet Oncol , vol.12 , pp. 1214-1221
    • Eapen, M.1    Klein, J.P.2    Sanz, G.F.3    Spellman, S.4    Ruggeri, A.5    Anasetti, C.6
  • 26
    • 0032006125 scopus 로고    scopus 로고
    • Nonmyeloablative stem cell transplantation and cell therapy as an alternative to conventional bone marrow transplantation with lethal cytoreduction for the treatment of malignant and nonmalignant hematologic diseases
    • Slavin S, Nagler A, Naparstek E, Kapelushnik Y, Aker M, Cividalli G, et al. Nonmyeloablative stem cell transplantation and cell therapy as an alternative to conventional bone marrow transplantation with lethal cytoreduction for the treatment of malignant and nonmalignant hematologic diseases. Blood (1998) 91:756-63.
    • (1998) Blood , vol.91 , pp. 756-763
    • Slavin, S.1    Nagler, A.2    Naparstek, E.3    Kapelushnik, Y.4    Aker, M.5    Cividalli, G.6
  • 27
    • 0033230960 scopus 로고    scopus 로고
    • Engraftment kinetics after nonmyeloablative allogeneic peripheral blood stem cell transplantation: full donor T-cell chimerism precedes alloimmune responses
    • Childs R, Clave E, Contentin N, Jayasekera D, Hensel N, Leitman S, et al. Engraftment kinetics after nonmyeloablative allogeneic peripheral blood stem cell transplantation: full donor T-cell chimerism precedes alloimmune responses. Blood (1999) 94:3234-41.
    • (1999) Blood , vol.94 , pp. 3234-3241
    • Childs, R.1    Clave, E.2    Contentin, N.3    Jayasekera, D.4    Hensel, N.5    Leitman, S.6
  • 28
    • 0033594552 scopus 로고    scopus 로고
    • Mixed lymphohaemopoietic chimerism and graft-versus lymphoma effects after non-myeloablative therapy and HLA-mismatched bone-marrow transplantation
    • doi:10.1016/S0140-6736(98)11135-2
    • Sykes M, Preffer F, McAfee S, Saidman SL, Weymouth D, Andrews DM, et al. Mixed lymphohaemopoietic chimerism and graft-versus lymphoma effects after non-myeloablative therapy and HLA-mismatched bone-marrow transplantation. Lancet (1999) 353:1755-9. doi:10.1016/S0140-6736(98)11135-2
    • (1999) Lancet , vol.353 , pp. 1755-1759
    • Sykes, M.1    Preffer, F.2    McAfee, S.3    Saidman, S.L.4    Weymouth, D.5    Andrews, D.M.6
  • 29
    • 0031879197 scopus 로고    scopus 로고
    • Transplant-lite: induction of graft-versus-malignancy using fludarabine-based nonablative chemotherapy and allogeneic blood progenitor-cell transplantation as treatment for lymphoid malignancies
    • Khouri IF, Keating M, Körbling M, Przepiorka D, Anderlini P, O'Brien S, et al. Transplant-lite: induction of graft-versus-malignancy using fludarabine-based nonablative chemotherapy and allogeneic blood progenitor-cell transplantation as treatment for lymphoid malignancies. J Clin Oncol (1998) 16:2817-24.
    • (1998) J Clin Oncol , vol.16 , pp. 2817-2824
    • Khouri, I.F.1    Keating, M.2    Körbling, M.3    Przepiorka, D.4    Anderlini, P.5    O'Brien, S.6
  • 30
    • 0034648702 scopus 로고    scopus 로고
    • Regression of metastatic renal-cell carcinoma after nonmyeloablative allogeneic peripheral-blood stem-cell transplantation
    • doi:10.1056/NEJM200009143431101
    • Childs R, Chernoff A, Contentin N, Bahceci E, Schrump D, Leitman S, et al. Regression of metastatic renal-cell carcinoma after nonmyeloablative allogeneic peripheral-blood stem-cell transplantation. N Engl J Med (2000) 343:750-8. doi:10.1056/NEJM200009143431101
    • (2000) N Engl J Med , vol.343 , pp. 750-758
    • Childs, R.1    Chernoff, A.2    Contentin, N.3    Bahceci, E.4    Schrump, D.5    Leitman, S.6
  • 31
    • 0035254219 scopus 로고    scopus 로고
    • Melphalan and purine analog-containing preparative regimens: reduced intensity conditioning for patients with hematologic malignancies undergoing allogeneic progenitor cell transplantation
    • doi:10.1182/blood.V97.3.631
    • Giralt S, Thall PF, Khouri I, Wang X, Braunschweig I, Ippolitti C, et al. Melphalan and purine analog-containing preparative regimens: reduced intensity conditioning for patients with hematologic malignancies undergoing allogeneic progenitor cell transplantation. Blood (2001) 97:631-7. doi:10.1182/blood.V97.3.631
    • (2001) Blood , vol.97 , pp. 631-637
    • Giralt, S.1    Thall, P.F.2    Khouri, I.3    Wang, X.4    Braunschweig, I.5    Ippolitti, C.6
  • 32
    • 0035383762 scopus 로고    scopus 로고
    • Hematopoietic cell transplantation in older patients with hematologic malignancies: replacing high-dose cytotoxic therapy with graft-versus tumor effects
    • doi:10.1182/blood.V97.11.3390
    • McSweeney PA, Niederwieser D, Shizuru JA, Sandmaier BM, Molina AJ, Maloney DG, et al. Hematopoietic cell transplantation in older patients with hematologic malignancies: replacing high-dose cytotoxic therapy with graft-versus tumor effects. Blood (2001) 97:3390-400. doi:10.1182/blood.V97.11.3390
    • (2001) Blood , vol.97 , pp. 3390-3400
    • McSweeney, P.A.1    Niederwieser, D.2    Shizuru, J.A.3    Sandmaier, B.M.4    Molina, A.J.5    Maloney, D.G.6
  • 33
    • 0035107047 scopus 로고    scopus 로고
    • Low-intensity conditioning is sufficient to ensure engraftment in matched unrelated bone marrow transplantation
    • doi:10.1016/S0301-472X(00)00655-X
    • Nagler A, Aker M, Or R, Naparstek E, Varadi G, Brautbar C, et al. Low-intensity conditioning is sufficient to ensure engraftment in matched unrelated bone marrow transplantation. Exp Hematol (2001) 29:362-70. doi:10.1016/S0301-472X(00)00655-X
    • (2001) Exp Hematol , vol.29 , pp. 362-370
    • Nagler, A.1    Aker, M.2    Or, R.3    Naparstek, E.4    Varadi, G.5    Brautbar, C.6
  • 34
    • 0036464657 scopus 로고    scopus 로고
    • Limiting transplantation-related mortality following unrelated donor stem cell transplantation by using a nonmyeloablative conditioning regimen
    • doi:10.1182/blood.V99.3.1071
    • Chakraverty R, Peggs K, Chopra R, Milligan DW, Kottaridis PD, Verfuerth S, et al. Limiting transplantation-related mortality following unrelated donor stem cell transplantation by using a nonmyeloablative conditioning regimen. Blood (2002) 99:1071-8. doi:10.1182/blood.V99.3.1071
    • (2002) Blood , vol.99 , pp. 1071-1078
    • Chakraverty, R.1    Peggs, K.2    Chopra, R.3    Milligan, D.W.4    Kottaridis, P.D.5    Verfuerth, S.6
  • 35
    • 0042441121 scopus 로고    scopus 로고
    • Rapid and complete donor chimerism in adult recipients of unrelated donor umbilical cord blood transplantation after reduced-intensity conditioning
    • doi:10.1182/blood-2002-11-3337
    • Barker JN, Weisdorf DJ, DeFor TE, Blazar BR, Miller JS, Wagner JE. Rapid and complete donor chimerism in adult recipients of unrelated donor umbilical cord blood transplantation after reduced-intensity conditioning. Blood (2003) 102:1915-9. doi:10.1182/blood-2002-11-3337
    • (2003) Blood , vol.102 , pp. 1915-1919
    • Barker, J.N.1    Weisdorf, D.J.2    DeFor, T.E.3    Blazar, B.R.4    Miller, J.S.5    Wagner, J.E.6
  • 36
    • 84862513845 scopus 로고    scopus 로고
    • Reduced-intensity conditioning transplantation in acute leukemia: the effect of source of unrelated donor stem cells on outcomes
    • doi:10.1182/blood-2011-12-400630
    • Brunstein CG, Eapen M, Ahn KW, Appelbaum FR, Ballen KK, Champlin RE, et al. Reduced-intensity conditioning transplantation in acute leukemia: the effect of source of unrelated donor stem cells on outcomes. Blood (2012) 119(23):5591-8. doi:10.1182/blood-2011-12-400630
    • (2012) Blood , vol.119 , Issue.23 , pp. 5591-5598
    • Brunstein, C.G.1    Eapen, M.2    Ahn, K.W.3    Appelbaum, F.R.4    Ballen, K.K.5    Champlin, R.E.6
  • 37
    • 0035859239 scopus 로고    scopus 로고
    • Creation of a double chimera after the transplantation of umbilical-cord blood from two partially matched unrelated donors
    • doi:10.1056/NEJM200106143442417
    • Barker JN, Weisdorf DJ, Wagner JE. Creation of a double chimera after the transplantation of umbilical-cord blood from two partially matched unrelated donors. N Engl J Med (2001) 344(24):1870-1. doi:10.1056/NEJM200106143442417
    • (2001) N Engl J Med , vol.344 , Issue.24 , pp. 1870-1871
    • Barker, J.N.1    Weisdorf, D.J.2    Wagner, J.E.3
  • 38
    • 18744374130 scopus 로고    scopus 로고
    • Double-chimaerism after transplantation of two human leucocyte antigen mismatched, unrelated cord blood units
    • doi:10.1046/j.1365-2141.2002.03893.x
    • De Lima M, St John LS, Wieder ED, Lee MS, McMannis J, Karandish S, et al. Double-chimaerism after transplantation of two human leucocyte antigen mismatched, unrelated cord blood units. Br J Haematol (2002) 119(3):773-6. doi:10.1046/j.1365-2141.2002.03893.x
    • (2002) Br J Haematol , vol.119 , Issue.3 , pp. 773-776
    • De Lima, M.1    St John, L.S.2    Wieder, E.D.3    Lee, M.S.4    McMannis, J.5    Karandish, S.6
  • 39
    • 12844273651 scopus 로고    scopus 로고
    • Transplantation of 2 partially HLA-matched umbilical cord blood units to enhance engraftment in adults with hematologic malignancy
    • Barker JN, Weisdorf DJ, DeFor TE, Blazar BR, McGlave PB, Miller JS, et al. Transplantation of 2 partially HLA-matched umbilical cord blood units to enhance engraftment in adults with hematologic malignancy. Blood (2005) 105:1343-7.
    • (2005) Blood , vol.105 , pp. 1343-1347
    • Barker, J.N.1    Weisdorf, D.J.2    DeFor, T.E.3    Blazar, B.R.4    McGlave, P.B.5    Miller, J.S.6
  • 40
    • 64049100784 scopus 로고    scopus 로고
    • Acute graft-versus-host disease after unrelated donor umbilical cord blood transplantation: analysis of risk factors
    • doi:10.1182/blood-2008-07-163238
    • MacMillan ML, Weisdorf DJ, Brunstein CG, Cao Q, DeFor TE, Verneris MR, et al. Acute graft-versus-host disease after unrelated donor umbilical cord blood transplantation: analysis of risk factors. Blood (2009) 113:2410-5. doi:10.1182/blood-2008-07-163238
    • (2009) Blood , vol.113 , pp. 2410-2415
    • MacMillan, M.L.1    Weisdorf, D.J.2    Brunstein, C.G.3    Cao, Q.4    DeFor, T.E.5    Verneris, M.R.6
  • 41
    • 35548984981 scopus 로고    scopus 로고
    • Umbilical cord blood transplantation after nonmyeloablative conditioning: impact on transplantation outcomes in 110 adults with hematologic disease
    • doi:10.1182/blood-2007-04-067215
    • Brunstein CG, Barker JN, Weisdorf DJ, DeFor TE, Miller JS, Blazar BR, et al. Umbilical cord blood transplantation after nonmyeloablative conditioning: impact on transplantation outcomes in 110 adults with hematologic disease. Blood (2007) 110(8):3064-70. doi:10.1182/blood-2007-04-067215
    • (2007) Blood , vol.110 , Issue.8 , pp. 3064-3070
    • Brunstein, C.G.1    Barker, J.N.2    Weisdorf, D.J.3    DeFor, T.E.4    Miller, J.S.5    Blazar, B.R.6
  • 42
    • 84863728643 scopus 로고    scopus 로고
    • Prospective study of single vs. two unit umbilical cord blood transplantation following reduced intensity conditioning in adults with hematologic malignancies
    • doi:10.1038/bmt.2011.195
    • Kindwall-Keller TL, Hegerfeldt Y, Meyerson HJ, Margevicius S, Fu P, van Heeckeren W, et al. Prospective study of single vs. two unit umbilical cord blood transplantation following reduced intensity conditioning in adults with hematologic malignancies. Bone Marrow Transplant (2012) 47(7):924-33. doi:10.1038/bmt.2011.195
    • (2012) Bone Marrow Transplant , vol.47 , Issue.7 , pp. 924-933
    • Kindwall-Keller, T.L.1    Hegerfeldt, Y.2    Meyerson, H.J.3    Margevicius, S.4    Fu, P.5    van Heeckeren, W.6
  • 43
    • 84891096048 scopus 로고    scopus 로고
    • No Survival Advantage after Double Umbilical Cord Blood (UCB) Compared to Single UCB Transplant in Children with Hematological Malignancy: Results of the Blood and Marrow Transplant Clinical Trials Network (BMT CTN 0501) Randomized Trial [Presentation]
    • Wagner JE, Eapen M, Carter SL, Haut PR, Peres E, Schultz KR, et al. No Survival Advantage after Double Umbilical Cord Blood (UCB) Compared to Single UCB Transplant in Children with Hematological Malignancy: Results of the Blood and Marrow Transplant Clinical Trials Network (BMT CTN 0501) Randomized Trial [Presentation]. ASH (2012).
    • (2012) ASH
    • Wagner, J.E.1    Eapen, M.2    Carter, S.L.3    Haut, P.R.4    Peres, E.5    Schultz, K.R.6
  • 44
    • 78649462137 scopus 로고    scopus 로고
    • Allogeneic hematopoietic cell transplantation for hematologic malignancy: relative risks and benefits of double umbilical cord blood
    • doi:10.1182/blood-2010-05-285304
    • Brunstein CG, Gutman JA, Weisdorf DJ, Woolfrey AE, Defor TE, Gooley TA, et al. Allogeneic hematopoietic cell transplantation for hematologic malignancy: relative risks and benefits of double umbilical cord blood. Blood (2010) 116:4693-9. doi:10.1182/blood-2010-05-285304
    • (2010) Blood , vol.116 , pp. 4693-4699
    • Brunstein, C.G.1    Gutman, J.A.2    Weisdorf, D.J.3    Woolfrey, A.E.4    Defor, T.E.5    Gooley, T.A.6
  • 45
    • 79953107633 scopus 로고    scopus 로고
    • Influence of infused cell dose and HLA-match on engraftment after double-unit cord blood allografts
    • doi:10.1182/blood-2010-08-300491
    • Avery S, Shi W, Lubin M, Gonzales AM, Heller G, Castro-Malaspina H, et al. Influence of infused cell dose and HLA-match on engraftment after double-unit cord blood allografts. Blood (2011) 117(12):3277-85. doi:10.1182/blood-2010-08-300491
    • (2011) Blood , vol.117 , Issue.12 , pp. 3277-3285
    • Avery, S.1    Shi, W.2    Lubin, M.3    Gonzales, A.M.4    Heller, G.5    Castro-Malaspina, H.6
  • 46
    • 33644545417 scopus 로고    scopus 로고
    • Unrelated cord blood transplants in adults with hematologic malignancies
    • Arcese W, Rocha V, Labopin M, Sanz G, Iori AP, de Lima M, et al. Unrelated cord blood transplants in adults with hematologic malignancies. Haematologica (2006) 91:223-30.
    • (2006) Haematologica , vol.91 , pp. 223-230
    • Arcese, W.1    Rocha, V.2    Labopin, M.3    Sanz, G.4    Iori, A.P.5    de Lima, M.6
  • 47
    • 77950364747 scopus 로고    scopus 로고
    • Combined effect of total nucleated cell dose and HLA match on transplant outcome in 1061 cord blood recipients with hematological malignancies
    • doi:10.1182/blood-2009-07-231068
    • Barker JN, Scaradavou A, Stevens CE. Combined effect of total nucleated cell dose and HLA match on transplant outcome in 1061 cord blood recipients with hematological malignancies. Blood (2010) 115(9):1843-9. doi:10.1182/blood-2009-07-231068
    • (2010) Blood , vol.115 , Issue.9 , pp. 1843-1849
    • Barker, J.N.1    Scaradavou, A.2    Stevens, C.E.3
  • 48
    • 79952171355 scopus 로고    scopus 로고
    • How I treat: the selection and acquisition of unrelated cord blood grafts
    • doi:10.1182/blood-2010-04-280966
    • Barker JN, Byam C, Scaradavou A. How I treat: the selection and acquisition of unrelated cord blood grafts. Blood (2011) 117(8):2332-9. doi:10.1182/blood-2010-04-280966
    • (2011) Blood , vol.117 , Issue.8 , pp. 2332-2339
    • Barker, J.N.1    Byam, C.2    Scaradavou, A.3
  • 49
    • 18244422194 scopus 로고    scopus 로고
    • Unrelated umbilical cord blood transplants in adults: early recovery of neutrophils by supportive co-transplantation of a low number of highly purified peripheral blood CD34+ cells from an HLA-haploidentical donor
    • doi:10.1016/S0301-472X(03)00067-5
    • Fernández MN, Regidor C, Cabrera R, García-Marco JA, Forés R, Sanjuán I, et al. Unrelated umbilical cord blood transplants in adults: early recovery of neutrophils by supportive co-transplantation of a low number of highly purified peripheral blood CD34+ cells from an HLA-haploidentical donor. Exp Hematol (2003) 31(6):535-44. doi:10.1016/S0301-472X(03)00067-5
    • (2003) Exp Hematol , vol.31 , Issue.6 , pp. 535-544
    • Fernández, M.N.1    Regidor, C.2    Cabrera, R.3    García-Marco, J.A.4    Forés, R.5    Sanjuán, I.6
  • 50
    • 83455259484 scopus 로고    scopus 로고
    • Reduced-intensity conditioning with combined haploidentical and cord blood transplantation results in rapid engraftment, low GVHD, and durable remissions
    • doi:10.1182/blood-2011-08-372508
    • Liu H, Rich ES, Godley L, Odenike O, Joseph L, Marino S, et al. Reduced-intensity conditioning with combined haploidentical and cord blood transplantation results in rapid engraftment, low GVHD, and durable remissions. Blood (2011) 118:6438-45. doi:10.1182/blood-2011-08-372508
    • (2011) Blood , vol.118 , pp. 6438-6445
    • Liu, H.1    Rich, E.S.2    Godley, L.3    Odenike, O.4    Joseph, L.5    Marino, S.6
  • 53
    • 32844456680 scopus 로고    scopus 로고
    • Superior ex vivo cord blood expansion following co-culture with bone marrow derived mesenchymal stem cells
    • doi:10.1038/sj.bmt.1705258
    • Robinson SN, Ng J, Niu T, Yang H, McMannis JD, Karandish S, et al. Superior ex vivo cord blood expansion following co-culture with bone marrow derived mesenchymal stem cells. Bone Marrow Transplant (2006) 37:359-66. doi:10.1038/sj.bmt.1705258
    • (2006) Bone Marrow Transplant , vol.37 , pp. 359-366
    • Robinson, S.N.1    Ng, J.2    Niu, T.3    Yang, H.4    McMannis, J.D.5    Karandish, S.6
  • 54
    • 84871071832 scopus 로고    scopus 로고
    • Cord-blood engraftment with ex vivo mesenchymal-cell coculture
    • doi:10.1056/NEJMoa1207285
    • de Lima M, McNiece I, Robinson SN, Munsell M, Eapen M, Horowitz M, et al. Cord-blood engraftment with ex vivo mesenchymal-cell coculture. N Eng J Med (2012) 367(24):2305-15. doi:10.1056/NEJMoa1207285
    • (2012) N Eng J Med , vol.367 , Issue.24 , pp. 2305-2315
    • de Lima, M.1    McNiece, I.2    Robinson, S.N.3    Munsell, M.4    Eapen, M.5    Horowitz, M.6
  • 55
    • 0026650764 scopus 로고
    • Direct contact between human primitive hematopoietic progenitors and bone marrow stroma is not required for long-term in vitro hematopoiesis
    • Verfaillie CM. Direct contact between human primitive hematopoietic progenitors and bone marrow stroma is not required for long-term in vitro hematopoiesis. Blood (1992) 79:2821-6.
    • (1992) Blood , vol.79 , pp. 2821-2826
    • Verfaillie, C.M.1
  • 56
    • 0024423440 scopus 로고
    • Role of the microenvironment on hematopoiesis. I. Stem cell differentiation into granulocytic and megakaryocytic cell lineage
    • Choudhury C. Role of the microenvironment on hematopoiesis. I. Stem cell differentiation into granulocytic and megakaryocytic cell lineage. J Lab Clin Med (1989) 114:378-81.
    • (1989) J Lab Clin Med , vol.114 , pp. 378-381
    • Choudhury, C.1
  • 57
    • 0008287244 scopus 로고
    • Generation of functional clonal cell lines from human bone marrow stroma
    • doi:10.1073/pnas.82.10.3477
    • Harigaya K, Handa H. Generation of functional clonal cell lines from human bone marrow stroma. Proc Natl Acad Sci U S A (1985) 82:3477-80. doi:10.1073/pnas.82.10.3477
    • (1985) Proc Natl Acad Sci U S A , vol.82 , pp. 3477-3480
    • Harigaya, K.1    Handa, H.2
  • 58
    • 0025108199 scopus 로고
    • Hemopoietic progenitor cell binding to the stromal microenvironment in vitro
    • Gordon MY, Clarke D, Atkinson J, Greaves MF. Hemopoietic progenitor cell binding to the stromal microenvironment in vitro. Exp Hematol (1990) 18:837-42.
    • (1990) Exp Hematol , vol.18 , pp. 837-842
    • Gordon, M.Y.1    Clarke, D.2    Atkinson, J.3    Greaves, M.F.4
  • 60
    • 0024521423 scopus 로고
    • Osteogenic stem cells and the stromal system of bone and marrow
    • Beresford JN. Osteogenic stem cells and the stromal system of bone and marrow. Clin Orthop Relat Res (1989) 240:270-80.
    • (1989) Clin Orthop Relat Res , vol.240 , pp. 270-280
    • Beresford, J.N.1
  • 62
    • 4243294729 scopus 로고    scopus 로고
    • Human mesenchymal stem cell support proliferation and multilineage differentiation of human hematopoietic stem cells
    • Cheng L, Mbalaviele G, Liu X. Human mesenchymal stem cell support proliferation and multilineage differentiation of human hematopoietic stem cells. Blood (1998) 92:57a.
    • (1998) Blood , vol.92
    • Cheng, L.1    Mbalaviele, G.2    Liu, X.3
  • 63
    • 63949085855 scopus 로고    scopus 로고
    • Transplantation of ex-vivo culture-expanded parental haploidentical mesenchymal stem cells to promote engraftment in pediatric recipients of unrelated donor umbilical cord blood: results of a phase I-II clinical trial
    • doi:10.1038/bmt.2008.348
    • MacMillan ML, Blazar BR, DeFor TE, Wagner JE. Transplantation of ex-vivo culture-expanded parental haploidentical mesenchymal stem cells to promote engraftment in pediatric recipients of unrelated donor umbilical cord blood: results of a phase I-II clinical trial. Bone Marrow Transplant (2009) 43:447-54. doi:10.1038/bmt.2008.348
    • (2009) Bone Marrow Transplant , vol.43 , pp. 447-454
    • MacMillan, M.L.1    Blazar, B.R.2    DeFor, T.E.3    Wagner, J.E.4
  • 64
    • 0036177511 scopus 로고    scopus 로고
    • Cellular copper content modulates differentiation and self-renewal in cultures of cord blood-derived CD34+ cells
    • doi:10.1046/j.0007-1048.2001.03316.x
    • Peled T, Landau E, Prus E, Treves AJ, Nagler A, Fibach E. Cellular copper content modulates differentiation and self-renewal in cultures of cord blood-derived CD34+ cells. Br J Haematol (2002) 116:655-61. doi:10.1046/j.0007-1048.2001.03316.x
    • (2002) Br J Haematol , vol.116 , pp. 655-661
    • Peled, T.1    Landau, E.2    Prus, E.3    Treves, A.J.4    Nagler, A.5    Fibach, E.6
  • 65
    • 26244435951 scopus 로고    scopus 로고
    • Chelatable cellular copper modulates differentiation and self-renewal of cord blood-derived hematopoietic progenitor cells
    • doi:10.1016/j.exphem.2005.06.015
    • Peled T, Glukhman E, Hasson N, Adi S, Assor H, Yudin D, et al. Chelatable cellular copper modulates differentiation and self-renewal of cord blood-derived hematopoietic progenitor cells. Exp Hematol (2005) 33:1092-100. doi:10.1016/j.exphem.2005.06.015
    • (2005) Exp Hematol , vol.33 , pp. 1092-1100
    • Peled, T.1    Glukhman, E.2    Hasson, N.3    Adi, S.4    Assor, H.5    Yudin, D.6
  • 66
    • 4544362434 scopus 로고    scopus 로고
    • Pre-clinical development of cord blood-derived progenitor cell graft expanded ex vivo with cytokines and the polyamine copper chelator tetraethylenepentamine
    • doi:10.1080/14653240410004916
    • Peled T, Mandel J, Goudsmid RN, Landor C, Hasson N, Harati D, et al. Pre-clinical development of cord blood-derived progenitor cell graft expanded ex vivo with cytokines and the polyamine copper chelator tetraethylenepentamine. Cytotherapy (2004) 6:344-55. doi:10.1080/14653240410004916
    • (2004) Cytotherapy , vol.6 , pp. 344-355
    • Peled, T.1    Mandel, J.2    Goudsmid, R.N.3    Landor, C.4    Hasson, N.5    Harati, D.6
  • 67
    • 2942622157 scopus 로고    scopus 로고
    • Linear polyamine copper chelator tetraethylenepentamine augments long-term ex vivo expansion of cord blood-derived CD34+ cells and increases their engraftment potential in NOD/SCID mice
    • doi:10.1016/j.exphem.2004.03.002
    • Peled T, Landau E, Mandel J, Glukhman E, Goudsmid NR, Nagler A, et al. Linear polyamine copper chelator tetraethylenepentamine augments long-term ex vivo expansion of cord blood-derived CD34+ cells and increases their engraftment potential in NOD/SCID mice. Exp Hematol (2004) 32:547-55. doi:10.1016/j.exphem.2004.03.002
    • (2004) Exp Hematol , vol.32 , pp. 547-555
    • Peled, T.1    Landau, E.2    Mandel, J.3    Glukhman, E.4    Goudsmid, N.R.5    Nagler, A.6
  • 68
    • 43849087808 scopus 로고    scopus 로고
    • Transplantation of ex vivo expanded cord blood cells using the copper chelator tetraethylenepentamine: a phase I/II clinical trial
    • doi:10.1038/sj.bmt.1705979
    • de Lima M, McMannis J, Gee A, Komanduri K, Couriel D, Andersson BS, et al. Transplantation of ex vivo expanded cord blood cells using the copper chelator tetraethylenepentamine: a phase I/II clinical trial. Bone Marrow Transplant (2008) 41:771-8. doi:10.1038/sj.bmt.1705979
    • (2008) Bone Marrow Transplant , vol.41 , pp. 771-778
    • de Lima, M.1    McMannis, J.2    Gee, A.3    Komanduri, K.4    Couriel, D.5    Andersson, B.S.6
  • 69
    • 0034876802 scopus 로고    scopus 로고
    • Notch receptors and hematopoiesis
    • doi:10.1016/S0301-472X(01)00676-2
    • Kojika S, Griffin JD. Notch receptors and hematopoiesis. Exp Hematol (2001) 29(9):1041-52. doi:10.1016/S0301-472X(01)00676-2
    • (2001) Exp Hematol , vol.29 , Issue.9 , pp. 1041-1052
    • Kojika, S.1    Griffin, J.D.2
  • 71
    • 0034613734 scopus 로고    scopus 로고
    • The notch ligand jagged-1 represents a novel growth factor of human hematopoietic stem cells
    • doi:10.1084/jem.192.9.1365
    • Karanu FN, Murdoch B, Gallacher L, Wu DM, Koremoto M, Sakano S, et al. The notch ligand jagged-1 represents a novel growth factor of human hematopoietic stem cells. J Exp Med (2000) 192(9):1365-72. doi:10.1084/jem.192.9.1365
    • (2000) J Exp Med , vol.192 , Issue.9 , pp. 1365-1372
    • Karanu, F.N.1    Murdoch, B.2    Gallacher, L.3    Wu, D.M.4    Koremoto, M.5    Sakano, S.6
  • 72
    • 0035313174 scopus 로고    scopus 로고
    • Human homologues of Delta-1 and Delta-4 function as mitogenic regulators of primitive human hematopoietic cells
    • doi:10.1182/blood.V97.7.1960
    • Karanu FN, Murdoch B, Miyabayashi T, Ohno M, Koremoto M, Gallacher L, et al. Human homologues of Delta-1 and Delta-4 function as mitogenic regulators of primitive human hematopoietic cells. Blood (2001) 97(7):1960-7. doi:10.1182/blood.V97.7.1960
    • (2001) Blood , vol.97 , Issue.7 , pp. 1960-1967
    • Karanu, F.N.1    Murdoch, B.2    Miyabayashi, T.3    Ohno, M.4    Koremoto, M.5    Gallacher, L.6
  • 73
    • 0033694305 scopus 로고    scopus 로고
    • Pluripotent, cytokine-dependent, hematopoietic stem cells are immortalized by constitutive Notch1 signaling
    • doi:10.1038/81390
    • Varnum-Finney B, Xu L, Brashem-Stein C, Nourigat C, Flowers D, Bakkour S, et al. Pluripotent, cytokine-dependent, hematopoietic stem cells are immortalized by constitutive Notch1 signaling. Nat Med (2000) 6(11):1278-81. doi:10.1038/81390
    • (2000) Nat Med , vol.6 , Issue.11 , pp. 1278-1281
    • Varnum-Finney, B.1    Xu, L.2    Brashem-Stein, C.3    Nourigat, C.4    Flowers, D.5    Bakkour, S.6
  • 74
    • 76349113345 scopus 로고    scopus 로고
    • Notch mediated expansion of human cord blood progenitor cells capable of rapid myeloid reconstitution
    • doi:10.1038/nm.2080
    • Delaney C, Heimfeld S, Brashem-Stein C, Voorhies H, Manger RL, Bernstein ID. Notch mediated expansion of human cord blood progenitor cells capable of rapid myeloid reconstitution. Nat Med (2010) 16:232-6. doi:10.1038/nm.2080
    • (2010) Nat Med , vol.16 , pp. 232-236
    • Delaney, C.1    Heimfeld, S.2    Brashem-Stein, C.3    Voorhies, H.4    Manger, R.L.5    Bernstein, I.D.6
  • 75
    • 0033230393 scopus 로고    scopus 로고
    • Seeding efficiency of primitive human hematopoietic cells in nonobese diabetic/severe combined immune deficiency mice: implications for stem cell frequency assessment
    • vanHennik PB, de Koning AE, Ploemacher RE. Seeding efficiency of primitive human hematopoietic cells in nonobese diabetic/severe combined immune deficiency mice: implications for stem cell frequency assessment. Blood (1999) 94:3055-61.
    • (1999) Blood , vol.94 , pp. 3055-3061
    • vanHennik, P.B.1    de Koning, A.E.2    Ploemacher, R.E.3
  • 76
    • 0033400586 scopus 로고    scopus 로고
    • Bone marrow cell trafficking following intravenous administration
    • doi:10.1046/j.1365-2141.1999.01779.x
    • Cui J, Wahl RL, Shen T, Fisher SJ, Recker E, Ginsburg D, et al. Bone marrow cell trafficking following intravenous administration. Br J Haematol (1999) 107:895-902. doi:10.1046/j.1365-2141.1999.01779.x
    • (1999) Br J Haematol , vol.107 , pp. 895-902
    • Cui, J.1    Wahl, R.L.2    Shen, T.3    Fisher, S.J.4    Recker, E.5    Ginsburg, D.6
  • 77
    • 0035874547 scopus 로고    scopus 로고
    • Intra-bone marrow injection of allogeneic bone marrow cells: a powerful new strategy for treatment of intractable autoimmune diseases in MRL/lpr mice
    • doi:10.1182/blood.V97.10.3292
    • Kushida T, Inaba M, Hisha H, Ichioka N, Esumi T, Ogawa R, et al. Intra-bone marrow injection of allogeneic bone marrow cells: a powerful new strategy for treatment of intractable autoimmune diseases in MRL/lpr mice. Blood (2001) 97:3292-9. doi:10.1182/blood.V97.10.3292
    • (2001) Blood , vol.97 , pp. 3292-3299
    • Kushida, T.1    Inaba, M.2    Hisha, H.3    Ichioka, N.4    Esumi, T.5    Ogawa, R.6
  • 78
    • 0037111735 scopus 로고    scopus 로고
    • Murine hematopoietic stem cell distribution and proliferation in ablated and nonablated bone marrow transplantation
    • doi:10.1182/blood-2002-04-1256
    • Zhong JF, Zhan Y, Anderson WF, Zhao Y. Murine hematopoietic stem cell distribution and proliferation in ablated and nonablated bone marrow transplantation. Blood (2002) 100:3521-6. doi:10.1182/blood-2002-04-1256
    • (2002) Blood , vol.100 , pp. 3521-3526
    • Zhong, J.F.1    Zhan, Y.2    Anderson, W.F.3    Zhao, Y.4
  • 79
    • 0038379165 scopus 로고    scopus 로고
    • Rapid myeloerythroid repopulation after intrafemoral transplantation of NOD-SCID mice reveals a new class of human stem cells
    • doi:10.1038/nm886
    • Mazurier F, Doedens M, Gan OI, Dick JE. Rapid myeloerythroid repopulation after intrafemoral transplantation of NOD-SCID mice reveals a new class of human stem cells. Nat Med (2003) 9:959-63. doi:10.1038/nm886
    • (2003) Nat Med , vol.9 , pp. 959-963
    • Mazurier, F.1    Doedens, M.2    Gan, O.I.3    Dick, J.E.4
  • 80
    • 0037783434 scopus 로고    scopus 로고
    • A highly sensitive strategy for SCID repopulating cell assay by direct injection of primitive human hematopoietic cells into NOD/SCID mice bone marrow
    • doi:10.1182/blood-2002-07-1995
    • Yahata T, Ando K, Sato T, Miyatake H, Nakamura Y, Muguruma Y, et al. A highly sensitive strategy for SCID repopulating cell assay by direct injection of primitive human hematopoietic cells into NOD/SCID mice bone marrow. Blood (2003) 101:2905-13. doi:10.1182/blood-2002-07-1995
    • (2003) Blood , vol.101 , pp. 2905-2913
    • Yahata, T.1    Ando, K.2    Sato, T.3    Miyatake, H.4    Nakamura, Y.5    Muguruma, Y.6
  • 81
    • 0038281385 scopus 로고    scopus 로고
    • SCID-repopulating cell activity of human cord blood derived CD34-cells assured by intra-bone marrow injection
    • doi:10.1182/blood-2002-09-2782
    • Wang J, Kimura T, Asada R, Harada S, Yokota S, Kawamoto Y, et al. SCID-repopulating cell activity of human cord blood derived CD34-cells assured by intra-bone marrow injection. Blood (2003) 101:2924-31. doi:10.1182/blood-2002-09-2782
    • (2003) Blood , vol.101 , pp. 2924-2931
    • Wang, J.1    Kimura, T.2    Asada, R.3    Harada, S.4    Yokota, S.5    Kawamoto, Y.6
  • 82
    • 4143092638 scopus 로고    scopus 로고
    • Intra-bone marrow injection of bone marrow and cord blood cells: an alternative way of transplantation associated with a higher seeding efficiency
    • doi:10.1016/j.exphem.2004.05.026
    • Castello S, Podestà M, Menditto VG, Ibatici A, Pitto A, Figari O, et al. Intra-bone marrow injection of bone marrow and cord blood cells: an alternative way of transplantation associated with a higher seeding efficiency. Exp Hematol (2004) 32:782-7. doi:10.1016/j.exphem.2004.05.026
    • (2004) Exp Hematol , vol.32 , pp. 782-787
    • Castello, S.1    Podestà, M.2    Menditto, V.G.3    Ibatici, A.4    Pitto, A.5    Figari, O.6
  • 83
    • 1442360601 scopus 로고    scopus 로고
    • Enhancement of allogeneic hematopoietic stem cell engraftment and prevention of GVHD by intra-bone marrow bone marrow transplantation plus donor lymphocyte infusion
    • doi:10.1634/stemcells.22-2-125
    • Nakamura K, Inaba M, Sugiura K, Yoshimura T, Kwon AH, Kamiyama Y, et al. Enhancement of allogeneic hematopoietic stem cell engraftment and prevention of GVHD by intra-bone marrow bone marrow transplantation plus donor lymphocyte infusion. Stem Cells (2004) 22:125-34. doi:10.1634/stemcells.22-2-125
    • (2004) Stem Cells , vol.22 , pp. 125-134
    • Nakamura, K.1    Inaba, M.2    Sugiura, K.3    Yoshimura, T.4    Kwon, A.H.5    Kamiyama, Y.6
  • 84
    • 67549119077 scopus 로고    scopus 로고
    • Allogeneic intra-BM-BMT plus adult thymus transplantation from same donor has benefits for long-term survival even after sublethal irradiation or low-dose BM cell injection
    • doi:10.1038/bmt.2008.396
    • Nishida T, Hosaka N, Takaki T, Miyake T, Cui W, Inaba M, et al. Allogeneic intra-BM-BMT plus adult thymus transplantation from same donor has benefits for long-term survival even after sublethal irradiation or low-dose BM cell injection. Bone Marrow Transplant (2009) 43:829-37. doi:10.1038/bmt.2008.396
    • (2009) Bone Marrow Transplant , vol.43 , pp. 829-837
    • Nishida, T.1    Hosaka, N.2    Takaki, T.3    Miyake, T.4    Cui, W.5    Inaba, M.6
  • 85
    • 61449148627 scopus 로고    scopus 로고
    • Adult thymus transplantation with allogeneic intra-bone marrow-bone marrow transplantation from same donor induces high thymopoiesis, mild graft-versus-host reaction and strong graft-versus-tumour effects
    • doi:10.1111/j.1365-2567.2008.02920.x
    • Miyake T, Hosaka N, Cui W, Nishida T, Takaki T, Inaba M, et al. Adult thymus transplantation with allogeneic intra-bone marrow-bone marrow transplantation from same donor induces high thymopoiesis, mild graft-versus-host reaction and strong graft-versus-tumour effects. Immunology (2009) 126:552-64. doi:10.1111/j.1365-2567.2008.02920.x
    • (2009) Immunology , vol.126 , pp. 552-564
    • Miyake, T.1    Hosaka, N.2    Cui, W.3    Nishida, T.4    Takaki, T.5    Inaba, M.6
  • 87
    • 49949091262 scopus 로고    scopus 로고
    • Direct intrabone transplant of unrelated cord-blood cells in acute leukaemia: a phase I/II study
    • doi:10.1016/S1470-2045(08)70180-3
    • Frassoni F, Gualandi F, Podesta M, Raiola AM, Ibatici A, Piaggio G, et al. Direct intrabone transplant of unrelated cord-blood cells in acute leukaemia: a phase I/II study. Lancet Oncol (2008) 9:831-9. doi:10.1016/S1470-2045(08)70180-3
    • (2008) Lancet Oncol , vol.9 , pp. 831-839
    • Frassoni, F.1    Gualandi, F.2    Podesta, M.3    Raiola, A.M.4    Ibatici, A.5    Piaggio, G.6
  • 88
    • 84871829759 scopus 로고    scopus 로고
    • Intrabone transplant of cord blood stem cells establishes a local engraftment store: a functional PET/FDG study
    • doi:10.1155/2012/767369
    • Marini C, Podestà M, Massollo M, Capitanio S, Fiz F, Morbelli S, et al. Intrabone transplant of cord blood stem cells establishes a local engraftment store: a functional PET/FDG study. J Biomed Biotechnol (2012) 2012:767369. doi:10.1155/2012/767369
    • (2012) J Biomed Biotechnol , vol.2012 , pp. 767369
    • Marini, C.1    Podestà, M.2    Massollo, M.3    Capitanio, S.4    Fiz, F.5    Morbelli, S.6
  • 89
    • 67649870299 scopus 로고    scopus 로고
    • Intra-BM injection to enhance engraftment after myeloablative umbilical cord blood transplantation with two partially HLA-matched units
    • doi:10.1038/bmt.2008.417
    • Brunstein CG, Barker JN, Weisdorf DJ, Defor TE, McKenna D, Chong SY, et al. Intra-BM injection to enhance engraftment after myeloablative umbilical cord blood transplantation with two partially HLA-matched units. Bone Marrow Transplant (2009) 43:935-40. doi:10.1038/bmt.2008.417
    • (2009) Bone Marrow Transplant , vol.43 , pp. 935-940
    • Brunstein, C.G.1    Barker, J.N.2    Weisdorf, D.J.3    Defor, T.E.4    McKenna, D.5    Chong, S.Y.6
  • 90
    • 84879560059 scopus 로고    scopus 로고
    • Effects of MSC-co-administration and route of delivery on cord blood hematopoietic stem cell engraftment
    • doi:10.3727/096368912X657431
    • Carrancio S, Romo C, Ramos T, Lopez-Holgado N, Muntion S, Prins HJ, et al. Effects of MSC-co-administration and route of delivery on cord blood hematopoietic stem cell engraftment. Cell Transplant (2013) 22(7):1171-83. doi:10.3727/096368912X657431
    • (2013) Cell Transplant , vol.22 , Issue.7 , pp. 1171-1183
    • Carrancio, S.1    Romo, C.2    Ramos, T.3    Lopez-Holgado, N.4    Muntion, S.5    Prins, H.J.6
  • 91
    • 84862777323 scopus 로고    scopus 로고
    • Ex vivo fucosylation improves human cord blood engraftment in NOD-SCID IL-2R?(null) mice
    • doi:10.1016/j.exphem.2012.01.015
    • Robinson SN, Simmons PJ, Thomas MW, Brouard N, Javni JA, Trilok S, et al. Ex vivo fucosylation improves human cord blood engraftment in NOD-SCID IL-2R?(null) mice. Exp Hematol (2012) 40(6):445-56. doi:10.1016/j.exphem.2012.01.015
    • (2012) Exp Hematol , vol.40 , Issue.6 , pp. 445-456
    • Robinson, S.N.1    Simmons, P.J.2    Thomas, M.W.3    Brouard, N.4    Javni, J.A.5    Trilok, S.6


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