메뉴 건너뛰기




Volumn 81, Issue 4, 2013, Pages 183-193

Dissecting graft-versus-leukemia from graft-versus-host-disease using novel strategies

Author keywords

Adoptive immunotherapy; Conditioning regimen; Graft versus host disease; Graft versus leukemia

Indexed keywords

CD40 LIGAND; CYCLOSPORIN; GLUCURONOSYLTRANSFERASE 2B7; HLA A ANTIGEN; HLA B ANTIGEN; HLA C ANTIGEN; HLA DRB1 ANTIGEN; INTERLEUKIN 2; IPILIMUMAB; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR 2DS1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; TACROLIMUS; THYMOCYTE ANTIBODY; TRANSCRIPTION FACTOR FOXP3; UNCLASSIFIED DRUG;

EID: 84875524917     PISSN: 00012815     EISSN: 13990039     Source Type: Journal    
DOI: 10.1111/tan.12090     Document Type: Review
Times cited : (67)

References (80)
  • 1
    • 0018764352 scopus 로고
    • Antileukemic effect of graft-versus-host disease in human recipients of allogeneic-marrow grafts
    • Weiden PL, Flournoy N, Thomas ED et al. Antileukemic effect of graft-versus-host disease in human recipients of allogeneic-marrow grafts. N Engl J Med 1979: 300: 1068-73.
    • (1979) N Engl J Med , vol.300 , pp. 1068-1073
    • Weiden, P.L.1    Flournoy, N.2    Thomas, E.D.3
  • 2
    • 0019861205 scopus 로고
    • Antileukemic effect of chronic graft-versus-host disease: contribution to improved survival after allogeneic marrow transplantation
    • Weiden PL, Sullivan KM, Flournoy N, Storb R, Thomas ED. Antileukemic effect of chronic graft-versus-host disease: contribution to improved survival after allogeneic marrow transplantation. N Engl J Med 1981: 304: 1529-33.
    • (1981) N Engl J Med , vol.304 , pp. 1529-1533
    • Weiden, P.L.1    Sullivan, K.M.2    Flournoy, N.3    Storb, R.4    Thomas, E.D.5
  • 3
    • 0025100777 scopus 로고
    • Graft-versus-leukemia reactions after bone marrow transplantation
    • Horowitz MM, Gale RP, Sondel PM et al. Graft-versus-leukemia reactions after bone marrow transplantation. Blood 1990: 75: 555-62.
    • (1990) Blood , vol.75 , pp. 555-562
    • Horowitz, M.M.1    Gale, R.P.2    Sondel, P.M.3
  • 4
    • 0036893195 scopus 로고    scopus 로고
    • Graft-versus-host disease and outcome in HLA-identical sibling transplantations for chronic myeloid leukemia
    • Gratwohl A, Brand R, Apperley J et al. Graft-versus-host disease and outcome in HLA-identical sibling transplantations for chronic myeloid leukemia. Blood 2002: 100: 3877-86.
    • (2002) Blood , vol.100 , pp. 3877-3886
    • Gratwohl, A.1    Brand, R.2    Apperley, J.3
  • 5
    • 84886954185 scopus 로고    scopus 로고
    • Impact of graft-versus-host disease on relapse after allogeneic hematopoietic stem cell transplantation, an EBMT megafile study
    • Stern M, de Wreede LC, Brand R et al. Impact of graft-versus-host disease on relapse after allogeneic hematopoietic stem cell transplantation, an EBMT megafile study. ASH Annual Meeting Abstracts 2012: 120: 469.
    • (2012) ASH Annual Meeting Abstracts , vol.120 , pp. 469
    • Stern, M.1    de Wreede, L.C.2    Brand, R.3
  • 6
    • 0037086131 scopus 로고    scopus 로고
    • Effectiveness of donor natural killer cell alloreactivity in mismatched hematopoietic transplants
    • Ruggeri L, Capanni M, Urbani E et al. Effectiveness of donor natural killer cell alloreactivity in mismatched hematopoietic transplants. Science 2002: 295: 2097-100.
    • (2002) Science , vol.295 , pp. 2097-2100
    • Ruggeri, L.1    Capanni, M.2    Urbani, E.3
  • 7
    • 34347396957 scopus 로고    scopus 로고
    • Donor natural killer cell allorecognition of missing self in haploidentical hematopoietic transplantation for acute myeloid leukemia: challenging its predictive value
    • Ruggeri L, Mancusi A, Capanni M et al. Donor natural killer cell allorecognition of missing self in haploidentical hematopoietic transplantation for acute myeloid leukemia: challenging its predictive value. Blood 2007.
    • (2007) Blood
    • Ruggeri, L.1    Mancusi, A.2    Capanni, M.3
  • 8
    • 68049118980 scopus 로고    scopus 로고
    • Loss of mismatched HLA in leukemia after stem-cell transplantation
    • Vago L, Perna SK, Zanussi M et al. Loss of mismatched HLA in leukemia after stem-cell transplantation. N Engl J Med 2009: 361: 478-88.
    • (2009) N Engl J Med , vol.361 , pp. 478-488
    • Vago, L.1    Perna, S.K.2    Zanussi, M.3
  • 9
    • 77951083382 scopus 로고    scopus 로고
    • Relapse of leukemia with loss of mismatched HLA resulting from uniparental disomy after haploidentical hematopoietic stem cell transplantation
    • Villalobos IB, Takahashi Y, Akatsuka Y et al. Relapse of leukemia with loss of mismatched HLA resulting from uniparental disomy after haploidentical hematopoietic stem cell transplantation. Blood 2010: 115: 3158-61.
    • (2010) Blood , vol.115 , pp. 3158-3161
    • Villalobos, I.B.1    Takahashi, Y.2    Akatsuka, Y.3
  • 10
    • 23944436856 scopus 로고    scopus 로고
    • Effect of graft-versus-host disease prophylaxis on 3-year disease-free survival in recipients of unrelated donor bone marrow (T-cell Depletion Trial): a multi-centre, randomised phase II-III trial
    • Wagner JE, Thompson JS, Carter SL, Kernan NA. Effect of graft-versus-host disease prophylaxis on 3-year disease-free survival in recipients of unrelated donor bone marrow (T-cell Depletion Trial): a multi-centre, randomised phase II-III trial. Lancet 2005: 366: 733-41.
    • (2005) Lancet , vol.366 , pp. 733-741
    • Wagner, J.E.1    Thompson, J.S.2    Carter, S.L.3    Kernan, N.A.4
  • 11
    • 0035992260 scopus 로고    scopus 로고
    • Infusion of CD4+ donor lymphocytes induces the expansion of CD8+ donor T cells with cytolytic activity directed against recipient hematopoietic cells
    • Zorn E, Wang KS, Hochberg EP et al. Infusion of CD4+ donor lymphocytes induces the expansion of CD8+ donor T cells with cytolytic activity directed against recipient hematopoietic cells. Clin Cancer Res 2002: 8: 2052-60.
    • (2002) Clin Cancer Res , vol.8 , pp. 2052-2060
    • Zorn, E.1    Wang, K.S.2    Hochberg, E.P.3
  • 12
    • 0036277759 scopus 로고    scopus 로고
    • Induction of HA-1-specific cytotoxic T-cell clones parallels the therapeutic effect of donor lymphocyte infusion
    • Kircher B, Stevanovic S, Urbanek M et al. Induction of HA-1-specific cytotoxic T-cell clones parallels the therapeutic effect of donor lymphocyte infusion. Br J Haematol 2002: 117: 935-9.
    • (2002) Br J Haematol , vol.117 , pp. 935-939
    • Kircher, B.1    Stevanovic, S.2    Urbanek, M.3
  • 13
    • 0037418284 scopus 로고    scopus 로고
    • Hematopoiesis-restricted minor histocompatibility antigens HA-1- or HA-2-specific T cells can induce complete remissions of relapsed leukemia
    • Marijt WA, Heemskerk MH, Kloosterboer FM et al. Hematopoiesis-restricted minor histocompatibility antigens HA-1- or HA-2-specific T cells can induce complete remissions of relapsed leukemia. Proc Natl Acad Sci U S A 2003: 100: 2742-7.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 2742-2747
    • Marijt, W.A.1    Heemskerk, M.H.2    Kloosterboer, F.M.3
  • 14
    • 0028871935 scopus 로고
    • CD8-depleted donor lymphocyte infusion as treatment for relapsed chronic myelogenous leukemia after allogeneic bone marrow transplantation
    • Giralt S, Hester J, Huh Y et al. CD8-depleted donor lymphocyte infusion as treatment for relapsed chronic myelogenous leukemia after allogeneic bone marrow transplantation. Blood 1995: 86: 4337-43.
    • (1995) Blood , vol.86 , pp. 4337-4343
    • Giralt, S.1    Hester, J.2    Huh, Y.3
  • 15
    • 20244374668 scopus 로고    scopus 로고
    • Toxicity and efficacy of defined doses of CD4(+) donor lymphocytes for treatment of relapse after allogeneic bone marrow transplant
    • Alyea EP, Soiffer RJ, Canning C et al. Toxicity and efficacy of defined doses of CD4(+) donor lymphocytes for treatment of relapse after allogeneic bone marrow transplant. Blood 1998: 91: 3671-80.
    • (1998) Blood , vol.91 , pp. 3671-3680
    • Alyea, E.P.1    Soiffer, R.J.2    Canning, C.3
  • 16
    • 6444219983 scopus 로고    scopus 로고
    • Expansion and activation of minor histocompatibility antigen HY-specific T cells associated with graft-versus-leukemia response
    • Takami A, Sugimori C, Feng X et al. Expansion and activation of minor histocompatibility antigen HY-specific T cells associated with graft-versus-leukemia response. Bone Marrow Transplant 2004: 34: 703-9.
    • (2004) Bone Marrow Transplant , vol.34 , pp. 703-709
    • Takami, A.1    Sugimori, C.2    Feng, X.3
  • 17
    • 6844237658 scopus 로고    scopus 로고
    • The minor histocompatibility antigen HA-1: a diallelic gene with a single amino acid polymorphism
    • den Haan JM, Meadows LM, Wang W et al. The minor histocompatibility antigen HA-1: a diallelic gene with a single amino acid polymorphism. Science 1998: 279: 1054-7.
    • (1998) Science , vol.279 , pp. 1054-1057
    • Den Haan, J.M.1    Meadows, L.M.2    Wang, W.3
  • 18
    • 0035862328 scopus 로고    scopus 로고
    • The immunogenicity of a new human minor histocompatibility antigen results from differential antigen processing
    • Brickner AG, Warren EH, Caldwell JA et al. The immunogenicity of a new human minor histocompatibility antigen results from differential antigen processing. J Exp Med 2001: 193: 195-206.
    • (2001) J Exp Med , vol.193 , pp. 195-206
    • Brickner, A.G.1    Warren, E.H.2    Caldwell, J.A.3
  • 19
    • 84975742565 scopus 로고    scopus 로고
    • 1000 Genomes Project Consortium. A map of human genome variation from population-scale sequencing
    • 1000 Genomes Project Consortium. A map of human genome variation from population-scale sequencing. Nature 2010: 467: 1061-73.
    • (2010) Nature , vol.467 , pp. 1061-1073
  • 20
    • 84867303407 scopus 로고    scopus 로고
    • Effect of MHC and non-MHC donor/recipient genetic disparity on the outcome of allogeneic HCT
    • Warren EH, Zhang XC, Li S et al. Effect of MHC and non-MHC donor/recipient genetic disparity on the outcome of allogeneic HCT. Blood 2012: 120: 2796-806.
    • (2012) Blood , vol.120 , pp. 2796-2806
    • Warren, E.H.1    Zhang, X.C.2    Li, S.3
  • 21
    • 0038190942 scopus 로고    scopus 로고
    • A human minor histocompatibility antigen resulting from differential expression due to a gene deletion
    • Murata M, Warren EH, Riddell SR. A human minor histocompatibility antigen resulting from differential expression due to a gene deletion. J Exp Med 2003: 197: 1279-89.
    • (2003) J Exp Med , vol.197 , pp. 1279-1289
    • Murata, M.1    Warren, E.H.2    Riddell, S.R.3
  • 22
    • 0033826799 scopus 로고    scopus 로고
    • Evidence that specific T lymphocytes may participate in the elimination of chronic myelogenous leukemia
    • Molldrem JJ, Lee PP, Wang C et al. Evidence that specific T lymphocytes may participate in the elimination of chronic myelogenous leukemia. Nat Med 2000: 6: 1018-23.
    • (2000) Nat Med , vol.6 , pp. 1018-1023
    • Molldrem, J.J.1    Lee, P.P.2    Wang, C.3
  • 23
    • 34548857324 scopus 로고    scopus 로고
    • Graft-versus-leukemia effects associated with detectable Wilms tumor-1 specific T lymphocytes following allogeneic stem cell transplantation for acute lymphoblastic leukemia (ALL)
    • Rezvani K, Yong AS, Savani BN et al. Graft-versus-leukemia effects associated with detectable Wilms tumor-1 specific T lymphocytes following allogeneic stem cell transplantation for acute lymphoblastic leukemia (ALL). Blood 2007: 110: 1924-32.
    • (2007) Blood , vol.110 , pp. 1924-1932
    • Rezvani, K.1    Yong, A.S.2    Savani, B.N.3
  • 24
    • 33846871255 scopus 로고    scopus 로고
    • Cancer-testis antigens are commonly expressed in multiple myeloma and induce systemic immunity following allogeneic stem cell transplantation
    • Atanackovic D, Arfsten J, Cao Y et al. Cancer-testis antigens are commonly expressed in multiple myeloma and induce systemic immunity following allogeneic stem cell transplantation. Blood 2007: 109: 1103-12.
    • (2007) Blood , vol.109 , pp. 1103-1112
    • Atanackovic, D.1    Arfsten, J.2    Cao, Y.3
  • 25
    • 77956811559 scopus 로고    scopus 로고
    • CD8(+) T-cell immunity against cancer-testis antigens develops following allogeneic stem cell transplantation and reveals a potential mechanism for the graft-versus-leukemia effect
    • McLarnon A, Piper KP, Goodyear OC et al. CD8(+) T-cell immunity against cancer-testis antigens develops following allogeneic stem cell transplantation and reveals a potential mechanism for the graft-versus-leukemia effect. Haematologica 2010: 95: 1572-8.
    • (2010) Haematologica , vol.95 , pp. 1572-1578
    • McLarnon, A.1    Piper, K.P.2    Goodyear, O.C.3
  • 26
    • 40549137442 scopus 로고    scopus 로고
    • Regression of human kidney cancer following allogeneic stem cell transplantation is associated with recognition of an HERV-E antigen by T cells
    • Takahashi Y, Harashima N, Kajigaya S et al. Regression of human kidney cancer following allogeneic stem cell transplantation is associated with recognition of an HERV-E antigen by T cells. J Clin Invest 2008: 118: 1099-109.
    • (2008) J Clin Invest , vol.118 , pp. 1099-1109
    • Takahashi, Y.1    Harashima, N.2    Kajigaya, S.3
  • 27
    • 23744449591 scopus 로고    scopus 로고
    • A defined donor activating natural killer cell receptor genotype protects against leukemic relapse after related HLA-identical hematopoietic stem cell transplantation
    • Verheyden S, Schots R, Duquet W, Demanet C. A defined donor activating natural killer cell receptor genotype protects against leukemic relapse after related HLA-identical hematopoietic stem cell transplantation. Leukemia 2005: 19: 1446-51.
    • (2005) Leukemia , vol.19 , pp. 1446-1451
    • Verheyden, S.1    Schots, R.2    Duquet, W.3    Demanet, C.4
  • 28
    • 20444394742 scopus 로고    scopus 로고
    • Improved outcome in HLA-identical sibling hematopoietic stem-cell transplantation for acute myelogenous leukemia predicted by KIR and HLA genotypes
    • Hsu KC, Keever-Taylor CA, Wilton A et al. Improved outcome in HLA-identical sibling hematopoietic stem-cell transplantation for acute myelogenous leukemia predicted by KIR and HLA genotypes. Blood 2005: 105: 4878-84.
    • (2005) Blood , vol.105 , pp. 4878-4884
    • Hsu, K.C.1    Keever-Taylor, C.A.2    Wilton, A.3
  • 29
    • 77955512395 scopus 로고    scopus 로고
    • Donor KIR Genes 2DL5A, 2DS1 and 3DS1 are associated with a reduced rate of leukemia relapse after HLA-identical sibling stem cell transplantation for acute myeloid leukemia but not other hematologic malignancies
    • Stringaris K, Adams S, Uribe M et al. Donor KIR Genes 2DL5A, 2DS1 and 3DS1 are associated with a reduced rate of leukemia relapse after HLA-identical sibling stem cell transplantation for acute myeloid leukemia but not other hematologic malignancies. Biol Blood Marrow Transplant 2010: 16: 1257-64.
    • (2010) Biol Blood Marrow Transplant , vol.16 , pp. 1257-1264
    • Stringaris, K.1    Adams, S.2    Uribe, M.3
  • 30
    • 33746031836 scopus 로고    scopus 로고
    • KIR ligands and prediction of relapse after unrelated donor hematopoietic cell transplantation for hematologic malignancy
    • Hsu KC, Gooley T, Malkki M et al. KIR ligands and prediction of relapse after unrelated donor hematopoietic cell transplantation for hematologic malignancy. Biol Blood Marrow Transplant 2006: 12: 828-36.
    • (2006) Biol Blood Marrow Transplant , vol.12 , pp. 828-836
    • Hsu, K.C.1    Gooley, T.2    Malkki, M.3
  • 31
    • 34247581578 scopus 로고    scopus 로고
    • Missing KIR ligands are associated with less relapse and increased graft-versus-host disease (GVHD) following unrelated donor allogeneic HCT
    • Miller JS, Cooley S, Parham P et al. Missing KIR ligands are associated with less relapse and increased graft-versus-host disease (GVHD) following unrelated donor allogeneic HCT. Blood 2007: 109: 5058-61.
    • (2007) Blood , vol.109 , pp. 5058-5061
    • Miller, J.S.1    Cooley, S.2    Parham, P.3
  • 32
    • 60249098439 scopus 로고    scopus 로고
    • Donors with group B KIR haplotypes improve relapse-free survival after unrelated hematopoietic cell transplantation for acute myelogenous leukemia
    • Cooley S, Trachtenberg E, Bergemann TL et al. Donors with group B KIR haplotypes improve relapse-free survival after unrelated hematopoietic cell transplantation for acute myelogenous leukemia. Blood 2009: 113: 726-32.
    • (2009) Blood , vol.113 , pp. 726-732
    • Cooley, S.1    Trachtenberg, E.2    Bergemann, T.L.3
  • 33
    • 77957734984 scopus 로고    scopus 로고
    • Donor selection for natural killer cell receptor genes leads to superior survival after unrelated transplantation for acute myelogenous leukemia
    • Cooley S, Weisdorf DJ, Guethlein LA et al. Donor selection for natural killer cell receptor genes leads to superior survival after unrelated transplantation for acute myelogenous leukemia. Blood 2010: 116: 2411-9.
    • (2010) Blood , vol.116 , pp. 2411-2419
    • Cooley, S.1    Weisdorf, D.J.2    Guethlein, L.A.3
  • 34
    • 84865454335 scopus 로고    scopus 로고
    • HLA-C-dependent prevention of leukemia relapse by donor activating KIR2DS1
    • Venstrom JM, Pittari G, Gooley TA et al. HLA-C-dependent prevention of leukemia relapse by donor activating KIR2DS1. N Engl J Med 2012: 367: 805-16.
    • (2012) N Engl J Med , vol.367 , pp. 805-816
    • Venstrom, J.M.1    Pittari, G.2    Gooley, T.A.3
  • 35
    • 0029902892 scopus 로고    scopus 로고
    • A p70 killer cell inhibitory receptor specific for several HLA-B allotypes discriminates among peptides bound to HLA-B*2705
    • Peruzzi M, Wagtmann N, Long EO. A p70 killer cell inhibitory receptor specific for several HLA-B allotypes discriminates among peptides bound to HLA-B*2705. J Exp Med 1996: 184: 1585-90.
    • (1996) J Exp Med , vol.184 , pp. 1585-1590
    • Peruzzi, M.1    Wagtmann, N.2    Long, E.O.3
  • 36
    • 0030948269 scopus 로고    scopus 로고
    • The direct binding of a p58 killer cell inhibitory receptor to human histocompatibility leukocyte antigen (HLA)-Cw4 exhibits peptide selectivity
    • Rajagopalan S, Long EO. The direct binding of a p58 killer cell inhibitory receptor to human histocompatibility leukocyte antigen (HLA)-Cw4 exhibits peptide selectivity. J Exp Med 1997: 185: 1523-8.
    • (1997) J Exp Med , vol.185 , pp. 1523-1528
    • Rajagopalan, S.1    Long, E.O.2
  • 37
    • 0034213423 scopus 로고    scopus 로고
    • Crystal structure of an NK cell immunoglobulin-like receptor in complex with its class I MHC ligand
    • Boyington JC, Motyka SA, Schuck P, Brooks AG, Sun PD. Crystal structure of an NK cell immunoglobulin-like receptor in complex with its class I MHC ligand. Nature 2000: 405: 537-43.
    • (2000) Nature , vol.405 , pp. 537-543
    • Boyington, J.C.1    Motyka, S.A.2    Schuck, P.3    Brooks, A.G.4    Sun, P.D.5
  • 38
    • 0035344199 scopus 로고    scopus 로고
    • Crystal structure of the human natural killer cell inhibitory receptor KIR2DL1-HLA-Cw4 complex
    • Fan QR, Long EO, Wiley DC. Crystal structure of the human natural killer cell inhibitory receptor KIR2DL1-HLA-Cw4 complex. Nat Immunol 2001: 2: 452-60.
    • (2001) Nat Immunol , vol.2 , pp. 452-460
    • Fan, Q.R.1    Long, E.O.2    Wiley, D.C.3
  • 39
    • 63749126940 scopus 로고    scopus 로고
    • What is the role for donor natural killer cells after nonmyeloablative conditioning?
    • Baron F, Petersdorf EW, Gooley T et al. What is the role for donor natural killer cells after nonmyeloablative conditioning? Biol Blood Marrow Transplant 2009: 15: 580-8.
    • (2009) Biol Blood Marrow Transplant , vol.15 , pp. 580-588
    • Baron, F.1    Petersdorf, E.W.2    Gooley, T.3
  • 40
    • 0033813320 scopus 로고    scopus 로고
    • Detection of a potent humoral response associated with immune-induced remission of chronic myelogenous leukemia
    • Wu CJ, Yang XF, McLaughlin S et al. Detection of a potent humoral response associated with immune-induced remission of chronic myelogenous leukemia. J Clin Invest 2000: 106: 705-14.
    • (2000) J Clin Invest , vol.106 , pp. 705-714
    • Wu, C.J.1    Yang, X.F.2    McLaughlin, S.3
  • 41
    • 20844450993 scopus 로고    scopus 로고
    • Graft-versus-tumor response in patients with multiple myeloma is associated with antibody response to BCMA, a plasma-cell membrane receptor
    • Bellucci R, Alyea EP, Chiaretti S et al. Graft-versus-tumor response in patients with multiple myeloma is associated with antibody response to BCMA, a plasma-cell membrane receptor. Blood 2005: 105: 3945-50.
    • (2005) Blood , vol.105 , pp. 3945-3950
    • Bellucci, R.1    Alyea, E.P.2    Chiaretti, S.3
  • 42
    • 49449115517 scopus 로고    scopus 로고
    • National marrow donor program HLA matching guidelines for unrelated adult donor hematopoietic cell transplants
    • Bray RA, Hurley CK, Kamani NR et al. National marrow donor program HLA matching guidelines for unrelated adult donor hematopoietic cell transplants. Biol Blood Marrow Transplant 2008: 14: 45-53.
    • (2008) Biol Blood Marrow Transplant , vol.14 , pp. 45-53
    • Bray, R.A.1    Hurley, C.K.2    Kamani, N.R.3
  • 43
    • 34948865802 scopus 로고    scopus 로고
    • High-risk HLA allele mismatch combinations responsible for severe acute graft-versus-host disease and implication for its molecular mechanism
    • Kawase T, Morishima Y, Matsuo K et al. High-risk HLA allele mismatch combinations responsible for severe acute graft-versus-host disease and implication for its molecular mechanism. Blood 2007: 110: 2235-41.
    • (2007) Blood , vol.110 , pp. 2235-2241
    • Kawase, T.1    Morishima, Y.2    Matsuo, K.3
  • 44
    • 38349017549 scopus 로고    scopus 로고
    • The importance of HLA-DPB1 in unrelated donor hematopoietic cell transplantation
    • Shaw BE, Gooley TA, Malkki M et al. The importance of HLA-DPB1 in unrelated donor hematopoietic cell transplantation. Blood 2007: 110: 4560-6.
    • (2007) Blood , vol.110 , pp. 4560-4566
    • Shaw, B.E.1    Gooley, T.A.2    Malkki, M.3
  • 45
    • 84859161258 scopus 로고    scopus 로고
    • Effect of T-cell-epitope matching at HLA-DPB1 in recipients of unrelated-donor haemopoietic-cell transplantation: a retrospective study
    • Fleischhauer K, Shaw BE, Gooley T et al. Effect of T-cell-epitope matching at HLA-DPB1 in recipients of unrelated-donor haemopoietic-cell transplantation: a retrospective study. Lancet Oncol 2012: 13: 366-74.
    • (2012) Lancet Oncol , vol.13 , pp. 366-374
    • Fleischhauer, K.1    Shaw, B.E.2    Gooley, T.3
  • 46
    • 63849288804 scopus 로고    scopus 로고
    • HLA mismatch combinations associated with decreased risk of relapse: implications for the molecular mechanism
    • Kawase T, Matsuo K, Kashiwase K et al. HLA mismatch combinations associated with decreased risk of relapse: implications for the molecular mechanism. Blood 2009: 113: 2851-8.
    • (2009) Blood , vol.113 , pp. 2851-2858
    • Kawase, T.1    Matsuo, K.2    Kashiwase, K.3
  • 47
    • 74249117356 scopus 로고    scopus 로고
    • Diverging effects of HLA-DPB1 matching status on outcome following unrelated donor transplantation depending on disease stage and the degree of matching for other HLA alleles
    • Shaw BE, Mayor NP, Russell NH et al. Diverging effects of HLA-DPB1 matching status on outcome following unrelated donor transplantation depending on disease stage and the degree of matching for other HLA alleles. Leukemia 2010: 24: 58-65.
    • (2010) Leukemia , vol.24 , pp. 58-65
    • Shaw, B.E.1    Mayor, N.P.2    Russell, N.H.3
  • 48
    • 84867592111 scopus 로고    scopus 로고
    • Peripheral-blood stem cells versus bone marrow from unrelated donors
    • Anasetti C, Logan BR, Lee SJ et al. Peripheral-blood stem cells versus bone marrow from unrelated donors. N Engl J Med 2012: 367: 1487-96.
    • (2012) N Engl J Med , vol.367 , pp. 1487-1496
    • Anasetti, C.1    Logan, B.R.2    Lee, S.J.3
  • 49
    • 0026030566 scopus 로고
    • Conditioning-related toxicity and acute graft-versus-host disease in patients given methotrexate/cyclosporine prophylaxis
    • Deeg HJ, Spitzer TR, Cottler-Fox M, Cahill R, Pickle LW. Conditioning-related toxicity and acute graft-versus-host disease in patients given methotrexate/cyclosporine prophylaxis. Bone Marrow Transplant 1991: 7: 193-8.
    • (1991) Bone Marrow Transplant , vol.7 , pp. 193-198
    • Deeg, H.J.1    Spitzer, T.R.2    Cottler-Fox, M.3    Cahill, R.4    Pickle, L.W.5
  • 50
    • 0025890204 scopus 로고
    • Allogeneic marrow transplantation in patients with chronic myeloid leukemia in the chronic phase: a randomized trial of two irradiation regimens
    • Clift RA, Buckner CD, Appelbaum FR et al. Allogeneic marrow transplantation in patients with chronic myeloid leukemia in the chronic phase: a randomized trial of two irradiation regimens. Blood 1991: 77: 1660-5.
    • (1991) Blood , vol.77 , pp. 1660-1665
    • Clift, R.A.1    Buckner, C.D.2    Appelbaum, F.R.3
  • 51
    • 0038494593 scopus 로고    scopus 로고
    • Graft-versus-host disease after nonmyeloablative versus conventional hematopoietic stem cell transplantation
    • Mielcarek M, Martin PJ, Leisenring W et al. Graft-versus-host disease after nonmyeloablative versus conventional hematopoietic stem cell transplantation. Blood 2003: 102: 756-62.
    • (2003) Blood , vol.102 , pp. 756-762
    • Mielcarek, M.1    Martin, P.J.2    Leisenring, W.3
  • 52
    • 77956271683 scopus 로고    scopus 로고
    • Impact of recipient statin treatment on graft-versus-host disease after allogeneic hematopoietic cell transplantation
    • Rotta M, Storer BE, Storb R et al. Impact of recipient statin treatment on graft-versus-host disease after allogeneic hematopoietic cell transplantation. Biol Blood Marrow Transplant 2010: 16: 1463-6.
    • (2010) Biol Blood Marrow Transplant , vol.16 , pp. 1463-1466
    • Rotta, M.1    Storer, B.E.2    Storb, R.3
  • 53
    • 77949500938 scopus 로고    scopus 로고
    • Donor statin treatment protects against severe acute graft-versus-host disease after related allogeneic hematopoietic cell transplantation
    • Rotta M, Storer BE, Storb RF et al. Donor statin treatment protects against severe acute graft-versus-host disease after related allogeneic hematopoietic cell transplantation. Blood 2010: 115: 1288-95.
    • (2010) Blood , vol.115 , pp. 1288-1295
    • Rotta, M.1    Storer, B.E.2    Storb, R.F.3
  • 54
    • 33745470309 scopus 로고    scopus 로고
    • Reduced incidence of acute and chronic graft-versus-host disease with the addition of thymoglobulin to a targeted busulfan/cyclophosphamide regimen
    • Deeg HJ, Storer BE, Boeckh M et al. Reduced incidence of acute and chronic graft-versus-host disease with the addition of thymoglobulin to a targeted busulfan/cyclophosphamide regimen. Biol Blood Marrow Transplant 2006: 12: 573-84.
    • (2006) Biol Blood Marrow Transplant , vol.12 , pp. 573-584
    • Deeg, H.J.1    Storer, B.E.2    Boeckh, M.3
  • 55
    • 79959496711 scopus 로고    scopus 로고
    • Impact of immune modulation with anti-T-cell antibodies on the outcome of reduced-intensity allogeneic hematopoietic stem cell transplantation for hematologic malignancies
    • Soiffer RJ, Lerademacher J, Ho V et al. Impact of immune modulation with anti-T-cell antibodies on the outcome of reduced-intensity allogeneic hematopoietic stem cell transplantation for hematologic malignancies. Blood 2011: 117: 6963-70.
    • (2011) Blood , vol.117 , pp. 6963-6970
    • Soiffer, R.J.1    Lerademacher, J.2    Ho, V.3
  • 56
    • 61849165013 scopus 로고    scopus 로고
    • CTLA4 blockade with ipilimumab to treat relapse of malignancy after allogeneic hematopoietic cell transplantation
    • Bashey A, Medina B, Corringham S et al. CTLA4 blockade with ipilimumab to treat relapse of malignancy after allogeneic hematopoietic cell transplantation. Blood 2009: 113: 1581-8.
    • (2009) Blood , vol.113 , pp. 1581-1588
    • Bashey, A.1    Medina, B.2    Corringham, S.3
  • 57
    • 79954592646 scopus 로고    scopus 로고
    • CTLA-4 blockade following relapse of malignancy after allogeneic stem cell transplantation is associated with T cell activation but not with increased levels of T regulatory cells
    • Zhou J, Bashey A, Zhong R et al. CTLA-4 blockade following relapse of malignancy after allogeneic stem cell transplantation is associated with T cell activation but not with increased levels of T regulatory cells. Biol Blood Marrow Transplant 2011: 17: 682-92.
    • (2011) Biol Blood Marrow Transplant , vol.17 , pp. 682-692
    • Zhou, J.1    Bashey, A.2    Zhong, R.3
  • 58
    • 84862859820 scopus 로고    scopus 로고
    • Safety, activity, and immune correlates of anti-PD-1 antibody in cancer
    • Topalian SL, Hodi FS, Brahmer JR et al. Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. N Engl J Med 2012: 366: 2443-54.
    • (2012) N Engl J Med , vol.366 , pp. 2443-2454
    • Topalian, S.L.1    Hodi, F.S.2    Brahmer, J.R.3
  • 59
    • 84862903106 scopus 로고    scopus 로고
    • Safety and activity of anti-PD-L1 antibody in patients with advanced cancer
    • Brahmer JR, Tykodi SS, Chow LQ et al. Safety and activity of anti-PD-L1 antibody in patients with advanced cancer. N Engl J Med 2012: 366: 2455-65.
    • (2012) N Engl J Med , vol.366 , pp. 2455-2465
    • Brahmer, J.R.1    Tykodi, S.S.2    Chow, L.Q.3
  • 60
    • 77955642823 scopus 로고    scopus 로고
    • CD4+CD25+ regulatory T cell depletion improves the graft-versus-tumor effect of donor lymphocytes after allogeneic hematopoietic stem cell transplantation
    • Maury S, Lemoine FM, Hicheri Y et al. CD4+CD25+ regulatory T cell depletion improves the graft-versus-tumor effect of donor lymphocytes after allogeneic hematopoietic stem cell transplantation. Sci Transl Med 2010: 2: 41-52.
    • (2010) Sci Transl Med , vol.2 , pp. 41-52
    • Maury, S.1    Lemoine, F.M.2    Hicheri, Y.3
  • 61
    • 0028914441 scopus 로고
    • Transfer of myeloma idiotype-specific immunity from an actively immunised marrow donor
    • Kwak LW, Taub DD, Duffey PL et al. Transfer of myeloma idiotype-specific immunity from an actively immunised marrow donor. Lancet 1995: 345: 1016-20.
    • (1995) Lancet , vol.345 , pp. 1016-1020
    • Kwak, L.W.1    Taub, D.D.2    Duffey, P.L.3
  • 62
    • 12944295304 scopus 로고    scopus 로고
    • Infusion of lymphocytes obtained from a donor immunised with the paraprotein idiotype as a treatment in a relapsed myeloma
    • Cabrera R, Diaz-Espada F, Barrios Y et al. Infusion of lymphocytes obtained from a donor immunised with the paraprotein idiotype as a treatment in a relapsed myeloma. Bone Marrow Transplant 2000: 25: 1105-8.
    • (2000) Bone Marrow Transplant , vol.25 , pp. 1105-1108
    • Cabrera, R.1    Diaz-Espada, F.2    Barrios, Y.3
  • 63
    • 23944475612 scopus 로고    scopus 로고
    • Tumor antigen immunization of sibling stem cell transplant donors in multiple myeloma
    • Neelapu SS, Munshi NC, Jagannath S et al. Tumor antigen immunization of sibling stem cell transplant donors in multiple myeloma. Bone Marrow Transplant 2005: 36: 315-23.
    • (2005) Bone Marrow Transplant , vol.36 , pp. 315-323
    • Neelapu, S.S.1    Munshi, N.C.2    Jagannath, S.3
  • 64
    • 79955966609 scopus 로고    scopus 로고
    • An anti-PR1/HLA-A2 T-cell receptor-like antibody mediates complement-dependent cytotoxicity against acute myeloid leukemia progenitor cells
    • Sergeeva A, Alatrash G, He H et al. An anti-PR1/HLA-A2 T-cell receptor-like antibody mediates complement-dependent cytotoxicity against acute myeloid leukemia progenitor cells. Blood 2011: 117: 4262-72.
    • (2011) Blood , vol.117 , pp. 4262-4272
    • Sergeeva, A.1    Alatrash, G.2    He, H.3
  • 65
    • 32644436462 scopus 로고    scopus 로고
    • Immunotherapy of high-risk acute leukemia with a recipient (autologous) vaccine expressing transgenic human CD40L and IL-2 after chemotherapy and allogeneic stem cell transplantation
    • Rousseau RF, Biagi E, Dutour A et al. Immunotherapy of high-risk acute leukemia with a recipient (autologous) vaccine expressing transgenic human CD40L and IL-2 after chemotherapy and allogeneic stem cell transplantation. Blood 2006: 107: 1332-41.
    • (2006) Blood , vol.107 , pp. 1332-1341
    • Rousseau, R.F.1    Biagi, E.2    Dutour, A.3
  • 66
    • 70349446800 scopus 로고    scopus 로고
    • Biologic activity of irradiated, autologous, GM-CSF-secreting leukemia cell vaccines early after allogeneic stem cell transplantation
    • Ho VT, Vanneman M, Kim H et al. Biologic activity of irradiated, autologous, GM-CSF-secreting leukemia cell vaccines early after allogeneic stem cell transplantation. Proc Natl Acad Sci U S A 2009: 106: 15825-30.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 15825-15830
    • Ho, V.T.1    Vanneman, M.2    Kim, H.3
  • 67
    • 0026648439 scopus 로고
    • Restoration of viral immunity in immunodeficient humans by the adoptive transfer of T cell clones
    • Riddell SR, Watanabe KS, Goodrich JM, Li CR, Agha ME, Greenberg PD. Restoration of viral immunity in immunodeficient humans by the adoptive transfer of T cell clones. Science 1992: 257: 238-41.
    • (1992) Science , vol.257 , pp. 238-241
    • Riddell, S.R.1    Watanabe, K.S.2    Goodrich, J.M.3    Li, C.R.4    Agha, M.E.5    Greenberg, P.D.6
  • 68
    • 0028816546 scopus 로고
    • Use of gene-modified virus-specific T lymphocytes to control Epstein-Barr-virus-related lymphoproliferation
    • Rooney CM, Smith CA, Ng CY et al. Use of gene-modified virus-specific T lymphocytes to control Epstein-Barr-virus-related lymphoproliferation. Lancet 1995: 345: 9-13.
    • (1995) Lancet , vol.345 , pp. 9-13
    • Rooney, C.M.1    Smith, C.A.2    Ng, C.Y.3
  • 69
    • 33749514632 scopus 로고    scopus 로고
    • Monoculture-derived T lymphocytes specific for multiple viruses expand and produce clinically relevant effects in immunocompromised individuals
    • Leen AM, Myers GD, Sili U et al. Monoculture-derived T lymphocytes specific for multiple viruses expand and produce clinically relevant effects in immunocompromised individuals. Nat Med 2006: 12: 1160-6.
    • (2006) Nat Med , vol.12 , pp. 1160-1166
    • Leen, A.M.1    Myers, G.D.2    Sili, U.3
  • 70
    • 70349247010 scopus 로고    scopus 로고
    • Functionally active virus-specific T cells that target CMV, adenovirus, and EBV can be expanded from naive T-cell populations in cord blood and will target a range of viral epitopes
    • Hanley PJ, Cruz CR, Savoldo B et al. Functionally active virus-specific T cells that target CMV, adenovirus, and EBV can be expanded from naive T-cell populations in cord blood and will target a range of viral epitopes. Blood 2009: 114: 1958-67.
    • (2009) Blood , vol.114 , pp. 1958-1967
    • Hanley, P.J.1    Cruz, C.R.2    Savoldo, B.3
  • 71
    • 1842631467 scopus 로고    scopus 로고
    • Reprogramming of virus-specific T cells into leukemia-reactive T cells using T cell receptor gene transfer
    • Heemskerk MH, Hoogeboom M, Hagedoorn R, Kester MG, Willemze R, Falkenburg JH. Reprogramming of virus-specific T cells into leukemia-reactive T cells using T cell receptor gene transfer. J Exp Med 2004: 199: 885-94.
    • (2004) J Exp Med , vol.199 , pp. 885-894
    • Heemskerk, M.H.1    Hoogeboom, M.2    Hagedoorn, R.3    Kester, M.G.4    Willemze, R.5    Falkenburg, J.H.6
  • 72
    • 13544273197 scopus 로고    scopus 로고
    • Enhanced antilymphoma efficacy of CD19-redirected influenza MP1-specific CTLs by cotransfer of T cells modified to present influenza MP1
    • Cooper LJ, Al-Kadhimi Z, Serrano LM et al. Enhanced antilymphoma efficacy of CD19-redirected influenza MP1-specific CTLs by cotransfer of T cells modified to present influenza MP1. Blood 2005: 105: 1622-31.
    • (2005) Blood , vol.105 , pp. 1622-1631
    • Cooper, L.J.1    Al-Kadhimi, Z.2    Serrano, L.M.3
  • 73
    • 77950993215 scopus 로고    scopus 로고
    • Derivation of human T lymphocytes from cord blood and peripheral blood with antiviral and antileukemic specificity from a single culture as protection against infection and relapse after stem cell transplantation
    • Micklethwaite KP, Savoldo B, Hanley PJ et al. Derivation of human T lymphocytes from cord blood and peripheral blood with antiviral and antileukemic specificity from a single culture as protection against infection and relapse after stem cell transplantation. Blood 2010: 115: 2695-703.
    • (2010) Blood , vol.115 , pp. 2695-2703
    • Micklethwaite, K.P.1    Savoldo, B.2    Hanley, P.J.3
  • 74
    • 78549278144 scopus 로고    scopus 로고
    • Eradication of B-lineage cells and regression of lymphoma in a patient treated with autologous T cells genetically engineered to recognize CD19
    • Kochenderfer JN, Wilson WH, Janik JE et al. Eradication of B-lineage cells and regression of lymphoma in a patient treated with autologous T cells genetically engineered to recognize CD19. Blood 2010: 116: 4099-102.
    • (2010) Blood , vol.116 , pp. 4099-4102
    • Kochenderfer, J.N.1    Wilson, W.H.2    Janik, J.E.3
  • 75
    • 79955517235 scopus 로고    scopus 로고
    • CD28 costimulation improves expansion and persistence of chimeric antigen receptor-modified T cells in lymphoma patients
    • Savoldo B, Ramos CA, Liu E et al. CD28 costimulation improves expansion and persistence of chimeric antigen receptor-modified T cells in lymphoma patients. J Clin Invest 2011: 121: 1822-6.
    • (2011) J Clin Invest , vol.121 , pp. 1822-1826
    • Savoldo, B.1    Ramos, C.A.2    Liu, E.3
  • 76
    • 80051720194 scopus 로고    scopus 로고
    • Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia
    • Porter DL, Levine BL, Kalos M, Bagg A, June CH. Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia. N Engl J Med 2011: 365: 725-33.
    • (2011) N Engl J Med , vol.365 , pp. 725-733
    • Porter, D.L.1    Levine, B.L.2    Kalos, M.3    Bagg, A.4    June, C.H.5
  • 77
    • 80455179612 scopus 로고    scopus 로고
    • Safety and persistence of adoptively transferred autologous CD19-targeted T cells in patients with relapsed or chemotherapy refractory B-cell leukemias
    • Brentjens RJ, Riviere I, Park JH et al. Safety and persistence of adoptively transferred autologous CD19-targeted T cells in patients with relapsed or chemotherapy refractory B-cell leukemias. Blood 2011: 118: 4817-28.
    • (2011) Blood , vol.118 , pp. 4817-4828
    • Brentjens, R.J.1    Riviere, I.2    Park, J.H.3
  • 78
    • 84863337890 scopus 로고    scopus 로고
    • B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimeric-antigen-receptor-transduced T cells
    • Kochenderfer JN, Dudley ME, Feldman SA et al. B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimeric-antigen-receptor-transduced T cells. Blood 2012: 119: 2709-20.
    • (2012) Blood , vol.119 , pp. 2709-2720
    • Kochenderfer, J.N.1    Dudley, M.E.2    Feldman, S.A.3
  • 79
    • 84866888649 scopus 로고    scopus 로고
    • Dramatic regression of chronic lymphocytic leukemia in the first patient treated with donor-derived genetically-engineered anti-CD19-chimeric-antigen-receptor-expressing T cells after allogeneic hematopoietic stem cell transplantation
    • Kochenderfer JN, Dudley ME, Maric I et al. Dramatic regression of chronic lymphocytic leukemia in the first patient treated with donor-derived genetically-engineered anti-CD19-chimeric-antigen-receptor-expressing T cells after allogeneic hematopoietic stem cell transplantation. Biol Blood Marrow Transplant 2011: 17: S158.
    • (2011) Biol Blood Marrow Transplant , vol.17
    • Kochenderfer, J.N.1    Dudley, M.E.2    Maric, I.3
  • 80
    • 84860681545 scopus 로고    scopus 로고
    • Editing T cell specificity towards leukemia by zinc finger nucleases and lentiviral gene transfer
    • Provasi E, Genovese P, Lombardo A et al. Editing T cell specificity towards leukemia by zinc finger nucleases and lentiviral gene transfer. Nat Med 2012: 18: 807-15.
    • (2012) Nat Med , vol.18 , pp. 807-815
    • Provasi, E.1    Genovese, P.2    Lombardo, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.