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Volumn 5, Issue , 2015, Pages

The anti-fibrotic effects of mesenchymal stem cells on irradiated lungs via stimulating endogenous secretion of HGF and PGE2

Author keywords

[No Author keywords available]

Indexed keywords

PROSTAGLANDIN E2; SCATTER FACTOR; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR;

EID: 84930003294     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep08713     Document Type: Article
Times cited : (79)

References (46)
  • 1
    • 22344448451 scopus 로고    scopus 로고
    • Non-small cell lung cancer therapy-related pulmonary toxicity: An update on radiation pneumonitis and fibrosis
    • Kong, F. M., Ten Haken, R., Eisbruch, A. & Lawrence, T. S. Non-small cell lung cancer therapy-related pulmonary toxicity: an update on radiation pneumonitis and fibrosis. SeminOncol. 32, S42-54 (2005).
    • (2005) SeminOncol. , vol.32 , pp. S42-54
    • Kong, F.M.1    Ten Haken, R.2    Eisbruch, A.3    Lawrence, T.S.4
  • 2
    • 38949148293 scopus 로고    scopus 로고
    • Radiation-induced lung injury. Assessment, management, and prevention
    • discussion 52-3
    • Ghafoori, P., Marks, L. B., Vujaskovic, Z. & Kelsey, C. R. Radiation-induced lung injury. assessment, management, and prevention. Oncology (Williston Park). 22, 37-47; discussion 52-3 (2008).
    • (2008) Oncology (Williston Park). , vol.22 , pp. 37-47
    • Ghafoori, P.1    Marks, L.B.2    Vujaskovic, Z.3    Kelsey, C.R.4
  • 3
    • 79960381007 scopus 로고    scopus 로고
    • Integrating mechanisms of pulmonary fibrosis
    • Wynn, T. A. Integrating mechanisms of pulmonary fibrosis. J Exp Med. 208, 1339-50 (2011).
    • (2011) J Exp Med. , vol.208 , pp. 1339-1350
    • Wynn, T.A.1
  • 4
    • 17844384822 scopus 로고    scopus 로고
    • Induction of epithelial-mesenchymal transition in alveolar epithelial cells by transforming growth factor-beta1: Potential role in idiopathic pulmonary fibrosis
    • Willis, B. C. et al. Induction of epithelial-mesenchymal transition in alveolar epithelial cells by transforming growth factor-beta1: potential role in idiopathic pulmonary fibrosis. Am J Pathol. 166, 1321-32 (2005).
    • (2005) Am J Pathol. , vol.166 , pp. 1321-1332
    • Willis, B.C.1
  • 5
    • 0142104985 scopus 로고    scopus 로고
    • Smad-dependent and smad-independent pathways in TGF-beta family signalling
    • Derynck, R. & Zhang, Y. E. Smad-dependent and smad-independent pathways in TGF-beta family signalling. Nature. 425, 577-584 (2003).
    • (2003) Nature. , vol.425 , pp. 577-584
    • Derynck, R.1    Zhang, Y.E.2
  • 6
    • 84859179083 scopus 로고    scopus 로고
    • Activation of canonical Wnt signaling is required for TGFb-mediated fibrosis
    • Akhmetshina, A. et al. Activation of canonical Wnt signaling is required for TGFb-mediated fibrosis. Nat Commun. 3, 735 (2012).
    • (2012) Nat Commun. , vol.3 , pp. 735
    • Akhmetshina, A.1
  • 7
    • 80052518623 scopus 로고    scopus 로고
    • Prostaglandin E2 and the pathogenesis of pulmonary fibrosis
    • Bozyk, P. D. &Moore, B. B. Prostaglandin E2 and the pathogenesis of pulmonary fibrosis. Am J Respir Cell Mol Biol. 45, 445-452 (2011).
    • (2011) Am J Respir Cell Mol Biol. , vol.45 , pp. 445-452
    • Bozyk, P.D.1    Moore, B.B.2
  • 8
    • 34548164083 scopus 로고    scopus 로고
    • Injured microenviroment directly guides the differentiation of engrafted Flk-1(1) mesenchymal stem cell in lung
    • Yan, X. et al. Injured microenviroment directly guides the differentiation of engrafted Flk-1(1) mesenchymal stem cell in lung. Exp Hematol. 35, 1466-1475 (2007).
    • (2007) Exp Hematol. , vol.35 , pp. 1466-1475
    • Yan, X.1
  • 9
    • 84875445041 scopus 로고    scopus 로고
    • Hepatocyte growth factor gene-modified mesenchymal stem cells reduce radiation-induced lung injury
    • Wang, H. et al. Hepatocyte growth factor gene-modified mesenchymal stem cells reduce radiation-induced lung injury. Hum Gene Ther. 24, 343-353 (2013).
    • (2013) Hum Gene Ther. , vol.24 , pp. 343-353
    • Wang, H.1
  • 10
    • 84873338888 scopus 로고    scopus 로고
    • Gene-modified mesenchymal stem cells protect against radiationinduced lung injury
    • Xue, J. et al. Gene-modified mesenchymal stem cells protect against radiationinduced lung injury. MolTher. 21, 456-465 (2013).
    • (2013) MolTher. , vol.21 , pp. 456-465
    • Xue, J.1
  • 11
    • 66349113736 scopus 로고    scopus 로고
    • Hepatocyte growth factor inhibits epithelial to myofibroblast transition in lung cells via Smad7
    • Shukla, M. N. et al. Hepatocyte growth factor inhibits epithelial to myofibroblast transition in lung cells via Smad7. Am J Respir Cell Mol Biol. 40, 643-53 (2009).
    • (2009) Am J Respir Cell Mol Biol. , vol.40 , pp. 643-653
    • Shukla, M.N.1
  • 12
    • 0031587828 scopus 로고    scopus 로고
    • The MAD-related protein Smad7 associates with the TGF beta receptor and functions as an antagonist of TGFbeta signaling
    • Hayashi, H. et al. The MAD-related protein Smad7 associates with the TGF beta receptor and functions as an antagonist of TGFbeta signaling. Cell. 89, 1165-73 (1997).
    • (1997) Cell. , vol.89 , pp. 1165-1173
    • Hayashi, H.1
  • 13
    • 4444269045 scopus 로고    scopus 로고
    • Characterization and expression analysis of mesenchymal stem cells from human bone marrow and adipose tissue
    • Lee, R. H. et al. Characterization and expression analysis of mesenchymal stem cells from human bone marrow and adipose tissue. Cell PhysiolBiochem. 14, 311-24 (2004).
    • (2004) Cell PhysiolBiochem. , vol.14 , pp. 311-324
    • Lee, R.H.1
  • 14
    • 84899530769 scopus 로고    scopus 로고
    • Activated Wnt signaling induces myofibroblast differentiation of mesenchymal stem cells, contributing to pulmonary fibrosis
    • Sun, Z. et al. Activated Wnt signaling induces myofibroblast differentiation of mesenchymal stem cells, contributing to pulmonary fibrosis. Int J Mol Med. 33, 1097-109 (2014).
    • (2014) Int J Mol Med. , vol.33 , pp. 1097-1109
    • Sun, Z.1
  • 15
    • 84886256145 scopus 로고    scopus 로고
    • Inhibition of Wnt/b-catenin signaling promotes engraftment of mesenchymal stem cells to repair lung injury
    • Sun, Z. et al. Inhibition of Wnt/b-catenin signaling promotes engraftment of mesenchymal stem cells to repair lung injury. J Cell Physiol. 229, 213-24 (2014).
    • (2014) J Cell Physiol. , vol.229 , pp. 213-224
    • Sun, Z.1
  • 17
    • 33745503500 scopus 로고    scopus 로고
    • Local irradiation not only induces homing of human mesenchymal stem cells at exposed sites but promotes their widespread engraftment to multiple organs: A study of their quantitative distribution after irradiation damage
    • Francois, S. et al. Local irradiation not only induces homing of human mesenchymal stem cells at exposed sites but promotes their widespread engraftment to multiple organs: a study of their quantitative distribution after irradiation damage. Stem Cells. 24, 1020-9 (2006).
    • (2006) Stem Cells. , vol.24 , pp. 1020-1029
    • Francois, S.1
  • 18
    • 2942555661 scopus 로고    scopus 로고
    • Interations of chemokines and chemokine receptors mediate the migration of mesenchymal stem cells to the impaired site in the brain after hypoglossal nerve injury
    • Ji, J. F., He, B. P., Dheen, S. T. & Tay, S. S. Interations of chemokines and chemokine receptors mediate the migration of mesenchymal stem cells to the impaired site in the brain after hypoglossal nerve injury. Stem Cells. 22, 415-27 (2004).
    • (2004) Stem Cells. , vol.22 , pp. 415-427
    • Ji, J.F.1    He, B.P.2    Dheen, S.T.3    Tay, S.S.4
  • 19
    • 72849151523 scopus 로고    scopus 로고
    • Direct imaging of immune rejection and memory induction by allogeneic mesenchymal stromal cells
    • Zangi, L. et al. Direct imaging of immune rejection and memory induction by allogeneic mesenchymal stromal cells. Stem Cells. 27, 2865-74 (2009).
    • (2009) Stem Cells. , vol.27 , pp. 2865-2874
    • Zangi, L.1
  • 21
    • 0041349297 scopus 로고    scopus 로고
    • The immune privilege of corneal grafts
    • Niederkorn, J. Y. The immune privilege of corneal grafts. J Leukoc Biol. 74, 167-71 (2003).
    • (2003) J Leukoc Biol. , vol.74 , pp. 167-171
    • Niederkorn, J.Y.1
  • 22
    • 84872875594 scopus 로고    scopus 로고
    • Foxm1 transcription factor is required for lung fibrosis and epithelial-to-mesenchymal transition
    • Balli, D. et al. Foxm1 transcription factor is required for lung fibrosis and epithelial-to-mesenchymal transition. EMBO J. 32, 231-244 (2013).
    • (2013) EMBO J. , vol.32 , pp. 231-244
    • Balli, D.1
  • 23
    • 0032036338 scopus 로고    scopus 로고
    • Cyclooxygenase isoenzyme localization and mRNA expression in rat lungs
    • Ermert, L. Cyclooxygenase isoenzyme localization and mRNA expression in rat lungs. Am J Respir Cell Mol Biol. 18, 479-88 (1998).
    • (1998) Am J Respir Cell Mol Biol. , vol.18 , pp. 479-488
    • Ermert, L.1
  • 24
    • 42049114845 scopus 로고    scopus 로고
    • Hepatocyte growth factor regulates cyclooxygenase-2 expression via beta-catenin, Akt, and p42/p44 MAPK in human bronchial epithelial cells
    • Lee, Y. H., Suzuki, Y. J., Griffin, A. J. & Day, R. M. Hepatocyte growth factor regulates cyclooxygenase-2 expression via beta-catenin, Akt, and p42/p44 MAPK in human bronchial epithelial cells. Am J Physiol Lung Cell Mol Physiol. 294, L778-86 (2008).
    • (2008) Am J Physiol Lung Cell Mol Physiol. , vol.294 , pp. L778-L786
    • Lee, Y.H.1    Suzuki, Y.J.2    Griffin, A.J.3    Day, R.M.4
  • 25
    • 84857236729 scopus 로고    scopus 로고
    • ERK/GSK3b/Snail signaling mediates radiation-induced alveolar epithelial-to-mesenchymal transition
    • Nagarajan, D. et al. ERK/GSK3b/Snail signaling mediates radiation-induced alveolar epithelial-to-mesenchymal transition. Free RadicBiol Med. 52, 983-92 (2012).
    • (2012) Free RadicBiol Med. , vol.52 , pp. 983-992
    • Nagarajan, D.1
  • 26
    • 0342264524 scopus 로고    scopus 로고
    • Dose-dependent induction of transforming growth factor beta (TGF-beta) in the lung tissue of fibrosis-prone mice after thoracic irradiation
    • Rube, C. E. et al. Dose-dependent induction of transforming growth factor beta (TGF-beta) in the lung tissue of fibrosis-prone mice after thoracic irradiation. Int J Radiation OncolBiol Phys. 47, 1033-42 (2000).
    • (2000) Int J Radiation OncolBiol Phys. , vol.47 , pp. 1033-1042
    • Rube, C.E.1
  • 27
    • 84897938063 scopus 로고    scopus 로고
    • Mechanisms of cellular fibrosis associated with cancer regimen-related toxicities
    • Mancini, M. L. & Sonis, S. T. Mechanisms of cellular fibrosis associated with cancer regimen-related toxicities. Front Pharmacol. 5, 51 (2014).
    • (2014) Front Pharmacol. , vol.5 , pp. 51
    • Mancini, M.L.1    Sonis, S.T.2
  • 28
    • 51049093614 scopus 로고    scopus 로고
    • Fox M1 regulates transcription of JNK1 to promote the G1/S transition and tumor cell invasiveness
    • Wang, I. C. et al. Fox M1 regulates transcription of JNK1 to promote the G1/S transition and tumor cell invasiveness. J Biol Chem. 283, 20770-8 (2008).
    • (2008) J Biol Chem. , vol.283 , pp. 20770-20778
    • Wang, I.C.1
  • 29
    • 77950179422 scopus 로고    scopus 로고
    • Transplantation of human mesenchymal stem cells promotes functional improvement and increased expression of neurotrophic factor in a rat focal cerebral ischemia model
    • Wakabayashi, K. et al. Transplantation of human mesenchymal stem cells promotes functional improvement and increased expression of neurotrophic factor in a rat focal cerebral ischemia model. J Neurosci Res. 88, 1017-25 (2010).
    • (2010) J Neurosci Res. , vol.88 , pp. 1017-1025
    • Wakabayashi, K.1
  • 30
    • 84929997150 scopus 로고    scopus 로고
    • Human adipose-Derived Mesenchymal Stem Cells Improve Motor Functions and are Neuroprotective in the 6-Hydroxydopamine-Rat Model for Parkinson's Disease when Cultured in Monolayer Cultures but Suppress Hippocampal Neurogenesis and HippocampalMemory Function when Cultured in Spheroids
    • [Epub ahead of print](
    • Berg, J. et al. Human adipose-Derived Mesenchymal Stem Cells Improve Motor Functions and are Neuroprotective in the 6-Hydroxydopamine-Rat Model for Parkinson's Disease when Cultured in Monolayer Cultures but Suppress Hippocampal Neurogenesis and HippocampalMemory Function when Cultured in Spheroids. Stem Cell Rev. [Epub ahead of print](2014).
    • (2014) Stem Cell Rev
    • Berg, J.1
  • 31
    • 60449093316 scopus 로고    scopus 로고
    • Human adult stem cells derived from adipose tissue protect against experimental colitis and sepsis
    • Gonzalez-Rey, E. et al.Human adult stem cells derived from adipose tissue protect against experimental colitis and sepsis. Gut. 58, 929-39 (2009).
    • (2009) Gut. , vol.58 , pp. 929-939
    • Gonzalez-Rey, E.1
  • 32
    • 79251540540 scopus 로고    scopus 로고
    • Radiation rescue: Mesenchymal stromal cells protect from lethal irradiation
    • Lange, C. et al. Radiation rescue: mesenchymal stromal cells protect from lethal irradiation. PLoS One. 6, e14486 (2011).
    • (2011) PLoS One. , vol.6
    • Lange, C.1
  • 33
    • 84908636959 scopus 로고    scopus 로고
    • Paracrine effect of mesenchymal stem cells derived from human adipose tissue in bone regeneration
    • Linero, I. & Chaparro, O. Paracrine effect of mesenchymal stem cells derived from human adipose tissue in bone regeneration. PLoS One. 9, e107001 (2014).
    • (2014) PLoS One. , vol.9
    • Linero, I.1    Chaparro, O.2
  • 34
    • 16344367737 scopus 로고    scopus 로고
    • HGF reduces advancing lung fibrosis in mice: A potential role for MMP-dependent myofibroblast apoptosis
    • Mizuno, S., Matsumoto, K., Li, M. Y. & Nakamura, T. HGF reduces advancing lung fibrosis in mice: a potential role for MMP-dependent myofibroblast apoptosis. FASEB J. 19, 580-2 (2005).
    • (2005) FASEB J. , vol.19 , pp. 580-582
    • Mizuno, S.1    Matsumoto, K.2    Li, M.Y.3    Nakamura, T.4
  • 35
    • 84894572047 scopus 로고    scopus 로고
    • Regulation of matrix metalloproteinase-1,-3, and-9 in Mycobacterium tuberculosis-dependent respiratory network by the rapamycin-sensitive PI3K/p70(S6K) cascade
    • Singh, S., Saraiva, L., Elkington, P. T. & Friedland, J. S. Regulation of matrix metalloproteinase-1,-3, and-9 in Mycobacterium tuberculosis-dependent respiratory network by the rapamycin-sensitive PI3K/p70(S6K) cascade. FASEB J. 28, 85-93 (2014).
    • (2014) FASEB J. , vol.28 , pp. 85-93
    • Singh, S.1    Saraiva, L.2    Elkington, P.T.3    Friedland, J.S.4
  • 36
    • 0037309390 scopus 로고    scopus 로고
    • Alveolar epithelial cell inhibition of fibroblast proliferation is regulated by MCP-1/CCR2 and mediated by PGE2
    • Moore, B. B. et al. Alveolar epithelial cell inhibition of fibroblast proliferation is regulated by MCP-1/CCR2 and mediated by PGE2. Am J Physiol Lung Cell Mol Physiol. 284, L342-9 (2003).
    • (2003) Am J Physiol Lung Cell Mol Physiol. , vol.284 , pp. L342-L349
    • Moore, B.B.1
  • 37
    • 84855260438 scopus 로고    scopus 로고
    • Prostaglandin E2 as an inhibitory modulator of fibrogenesis in human lung allografts
    • Walker,N.M. et al. Prostaglandin E2 as an inhibitory modulator of fibrogenesis in human lung allografts. Am J Respir Crit Care Med. 185, 77-84 (2012).
    • (2012) Am J Respir Crit Care Med. , vol.185 , pp. 77-84
    • Walker, N.M.1
  • 38
    • 34547647436 scopus 로고    scopus 로고
    • PGE(2) inhibition of TGF-beta1-induced myofibroblast differentiation is Smad-independent but involves cell shape and adhesiondependent signaling
    • Thomas, P. E. et al. PGE(2) inhibition of TGF-beta1-induced myofibroblast differentiation is Smad-independent but involves cell shape and adhesiondependent signaling. Am J Physiol Lung Cell Mol Physiol. 293, L417-28 (2007).
    • (2007) Am J Physiol Lung Cell Mol Physiol. , vol.293 , pp. L417-L428
    • Thomas, P.E.1
  • 39
    • 13244258341 scopus 로고    scopus 로고
    • Prostaglandin E(2) inhibits fibroblast migration by E-prostanoid 2 receptor-mediated increase in PTEN activity
    • White, E. S. et al. Prostaglandin E(2) inhibits fibroblast migration by E-prostanoid 2 receptor-mediated increase in PTEN activity. Am J Respir Cell Mol Biol. 32, 135-41 (2005).
    • (2005) Am J Respir Cell Mol Biol. , vol.32 , pp. 135-141
    • White, E.S.1
  • 40
    • 77953189863 scopus 로고    scopus 로고
    • The antifibrotic effects of plasminogen activation occur via prostaglandin E2 synthesis in human and mice
    • Bauman, K. A. et al. The antifibrotic effects of plasminogen activation occur via prostaglandin E2 synthesis in human and mice. J Clin Invest. 120, 1950-60 (2010).
    • (2010) J Clin Invest. , vol.120 , pp. 1950-1960
    • Bauman, K.A.1
  • 41
    • 84929998816 scopus 로고    scopus 로고
    • Sublingual immunotherapy induces regulatory function of IL-10-expressing CD4(1)CD25(1)Foxp3(1) T cells of cervical lymph nodes in murine allergic rhinitis model
    • Yamada, T. et al. Sublingual Immunotherapy Induces Regulatory Function of IL-10-Expressing CD4(1)CD25(1)Foxp3(1) T Cells of Cervical Lymph Nodes in Murine Allergic Rhinitis Model. J Allergy (Cairo). 2012, 490905 (2012).
    • (2012) J Allergy (Cairo). , vol.2012 , pp. 490905
    • Yamada, T.1
  • 42
    • 84855511323 scopus 로고    scopus 로고
    • Multiple stromal populations contribute to pulmonary fibrosis without evidence for epithelial to mesenchymal transition
    • Rock, J. R. et al. Multiple stromal populations contribute to pulmonary fibrosis without evidence for epithelial to mesenchymal transition. Proc Natl Acad Sci U S A. 108, E1475-83 (2011).
    • (2011) Proc Natl Acad Sci U S A. , vol.108 , pp. E1475-E1483
    • Rock, J.R.1
  • 43
    • 1342268310 scopus 로고    scopus 로고
    • Bone marrow-derived progenitor cells in pulmonary fibrosis
    • Hashimoto, N. et al. Bone marrow-derived progenitor cells in pulmonary fibrosis. J Clin Invest. 113, 243-52 (2004).
    • (2004) J Clin Invest. , vol.113 , pp. 243-252
    • Hashimoto, N.1
  • 44
    • 84879680524 scopus 로고    scopus 로고
    • Multi-therapeutic effects of human adipose-derived mesenchymal stem cells on radiation-induced intestinal injury
    • Chang, P. et al.Multi-therapeutic effects of human adipose-derived mesenchymal stem cells on radiation-induced intestinal injury. Cell Death Dis. 4, e685 (2013).
    • (2013) Cell Death Dis. , vol.4 , pp. e685
    • Chang, P.1
  • 45
    • 18744373595 scopus 로고    scopus 로고
    • Human adipose tissue is a source of multipotent stem cells
    • Zuk, P. A. et al. Human adipose tissue is a source of multipotent stem cells. Mol Biol Cell. 13, 4279-95 (2002).
    • (2002) Mol Biol Cell. , vol.13 , pp. 4279-4295
    • Zuk, P.A.1
  • 46
    • 47049112539 scopus 로고    scopus 로고
    • Optimal blood mononuclear cell isolation procedures for gamma interferon enzyme-linked immunospot testing of healthy Swedish and Tanzanian subjects
    • Nilsson, C. et al.Optimal blood mononuclear cell isolation procedures for gamma interferon enzyme-linked immunospot testing of healthy Swedish and Tanzanian subjects. Clin Vaccine Immunol. 15, 585-9 (2008).
    • (2008) Clin Vaccine Immunol , vol.15 , pp. 585-589
    • Nilsson, C.1


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