LAPTM4b recruits the LAT1-4F2hc Leu transporter to lysosomes and promotes mTORC1 activation

Nature Communications

Volumn 6, Issue , 2015, Pages

  Milkereit, Ruth ^a   Persaud, Avinash ^a   Vanoaica, Liviu ^b   Guetg, Adriano ^b   Verrey, Francois ^b   Rotin, Daniela ^a  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; LEUCINE; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; AMINO ACID TRANSPORTER; LAPTM4B PROTEIN, HUMAN; MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 1; MEMBRANE PROTEIN; MULTIPROTEIN COMPLEX; ONCOPROTEIN; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; TARGET OF RAPAMYCIN KINASE;

AMINO ACID; MAMMAL; MEMBRANE; SIGNAL;

ARTICLE; AUTOPHAGY; CONTROLLED STUDY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; LYSOSOME; PROTEIN BINDING; PROTEIN TRANSPORT; HELA CELL LINE; METABOLISM;

MAMMALIA;

HELA CELLS; HUMANS; LARGE NEUTRAL AMINO ACID-TRANSPORTER 1; LEUCINE; LYSOSOMES; MEMBRANE PROTEINS; MULTIPROTEIN COMPLEXES; ONCOGENE PROTEINS; TOR SERINE-THREONINE KINASES; VACUOLAR PROTON-TRANSLOCATING ATPASES;

EID: 84929997950     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms8250     Document Type: Article

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