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Volumn 16, Issue 6, 2015, Pages 332-344

Epigenetic and transgenerational reprogramming of brain development

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTIVE BEHAVIOR; BODY COMPOSITION; BRAIN DEVELOPMENT; BRAIN FUNCTION; CHRONIC STRESS; COGNITIVE DEFECT; DISEASE PREDISPOSITION; DISEASE TRANSMISSION; DNA METHYLATION; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL FACTOR; EPIGENETICS; GENETICS; HUMAN; INFECTION; INFLAMMATION; MATERNAL NUTRITION; MATERNAL STRESS; NERVE CELL DIFFERENTIATION; NEURODEVELOPMENTAL PROGRAMMING; NONHUMAN; NUCLEAR REPROGRAMMING; OBESITY; ORGANISMAL INTERACTION; PATERNITY; PERINATAL PERIOD; PRENATAL PERIOD; PRENATAL STRESS; PRIORITY JOURNAL; REVIEW; SEX DIFFERENCE; VERBAL MEMORY; WORKING MEMORY; ANIMAL; BRAIN; EMBRYOLOGY; FEMALE; GENETIC EPIGENESIS; NERVOUS SYSTEM DEVELOPMENT; PHYSIOLOGY; PREGNANCY; PRENATAL EXPOSURE;

EID: 84929949604     PISSN: 1471003X     EISSN: 14710048     Source Type: Journal    
DOI: 10.1038/nrn3818     Document Type: Review
Times cited : (373)

References (180)
  • 1
    • 77955700847 scopus 로고    scopus 로고
    • Early life programming and neurodevelopmental disorders
    • Bale, T. L. et al. Early life programming and neurodevelopmental disorders. Biol. Psychiatry 68, 314-319 (2010).
    • (2010) Biol. Psychiatry , vol.68 , pp. 314-319
    • Bale, T.L.1
  • 2
    • 79951947900 scopus 로고    scopus 로고
    • Social influences on neurobiology and behavior: Epigenetic effects during development
    • Curley, J. P., Jensen, C. L., Mashoodh, R. & Champagne, F. A. Social influences on neurobiology and behavior: epigenetic effects during development. Psychoneuroendocrinology 36, 352-371 (2011).
    • (2011) Psychoneuroendocrinology , vol.36 , pp. 352-371
    • Curley, J.P.1    Jensen, C.L.2    Mashoodh, R.3    Champagne, F.A.4
  • 3
    • 84886683874 scopus 로고    scopus 로고
    • Epigenetic contributions to hormonally mediated sexual differentiation of the brain
    • McCarthy, M. M. & Nugent, B. M. Epigenetic contributions to hormonally mediated sexual differentiation of the brain. J. Neuroendocrinol. 25,1133-1140 (2013).
    • (2013) J. Neuroendocrinol , vol.25 , pp. 1133-1140
    • McCarthy, M.M.1    Nugent, B.M.2
  • 4
    • 84882788493 scopus 로고    scopus 로고
    • Sex stress, and epigenetics: Regulation of behavior in animal models of mood disorders
    • Hodes, G. E. Sex, stress, and epigenetics: regulation of behavior in animal models of mood disorders. Biol. Sex Differ. 4, 1 (2013).
    • (2013) Biol. Sex Differ , vol.4 , Issue.1
    • Hodes, G.E.1
  • 5
    • 84872849505 scopus 로고    scopus 로고
    • Tr ansgenerational epigenetic effects on brain functions
    • Bohacek, J., Gapp, K., Saab, B. J. & Mansuy, I. M. Tr ansgenerational epigenetic effects on brain functions. Biol. Psychiatry 73, 313-320 (2013).
    • (2013) Biol. Psychiatry , vol.73 , pp. 313-320
    • Bohacek, J.1    Gapp, K.2    Saab, B.J.3    Mansuy, I.M.4
  • 6
    • 0035704552 scopus 로고    scopus 로고
    • The thrifty phenotype hypothesis
    • In this paper, the thrifty phenotype hypothesis describes how a mismatch between fetal programming and the postnatal environment can result in disease risk
    • Hales, C. N. & Barker, D. J. The thrifty phenotype hypothesis. Br. Med. Bull. 60, 5-20 (2001).In this paper, the thrifty phenotype hypothesis describes how a mismatch between fetal programming and the postnatal environment can result in disease risk.
    • (2001) Br. Med. Bull , vol.60 , pp. 5-20
    • Hales, C.N.1    Barker, D.J.2
  • 7
    • 77952888304 scopus 로고    scopus 로고
    • The crf system, stres s, depression and anxiety-insights from human genetic studies
    • Binder, E. B. & Nemeroff, C. B. The CRF system, stres s, depression and anxiety-insights from human genetic studies. Mol. Psychiatry 15, 574-588 (2010).
    • (2010) Mol. Psychiatry , vol.15 , pp. 574-588
    • Binder, E.B.1    Nemeroff, C.B.2
  • 8
    • 77955951477 scopus 로고    scopus 로고
    • Socioeconomic status and the brain: Mecha nistic insights from human and animal research
    • Hackman, D. A., Farah, M. J. & Meaney, M. J. Socioeconomic status and the brain: mecha nistic insights from human and animal research. Nature Rev. Neurosci. 11, 651-659 (2010).
    • (2010) Nature Rev. Neurosci , vol.11 , pp. 651-659
    • Hackman, D.A.1    Farah, M.J.2    Meaney, M.J.3
  • 9
    • 84887009499 scopus 로고    scopus 로고
    • The emerging field of neuroepigenetics
    • Sweatt, J. D. The emerging field of neuroepigenetics. Neuron 80, 624-632 (2013).
    • (2013) Neuron , vol.80 , pp. 624-632
    • Sweatt, J.D.1
  • 11
    • 70349838218 scopus 로고    scopus 로고
    • Cytokines and cns development
    • Deverman, B. E. & Patterson, P. H. Cytokines and CNS development. Neuron 64, 61-78 (2009).
    • (2009) Neuron , vol.64 , pp. 61-78
    • Deverman, B.E.1    Patterson, P.H.2
  • 12
    • 84866748316 scopus 로고    scopus 로고
    • Prenat al programing: At the intersection of maternal stress and immune activation
    • Howerton, C. L. & Bale, T. L. Prenat al programing: at the intersection of maternal stress and immune activation. Horm. Behav. 62, 237-242 (2012).
    • (2012) Horm. Behav , vol.62 , pp. 237-242
    • Howerton, C.L.1    Bale, T.L.2
  • 13
    • 84865839322 scopus 로고    scopus 로고
    • Epidemiologic studies of exposure to prenatal infection and risk of schizophre nia and autism
    • Brown, A. S. Epidemiologic studies of exposure to prenatal infection and risk of schizophre nia and autism. Dev. Neurobiol. 72, 1272-1276 (2012).
    • (2012) Dev. Neurobiol , vol.72 , pp. 1272-1276
    • Brown, A.S.1
  • 14
    • 60549102450 scopus 로고    scopus 로고
    • Prenatal infection and cavum septum pellucidum in adult schizophrenia
    • Brown, A. S. et al. Prenatal infection and cavum septum pellucidum in adult schizophrenia. Schizophr. Res. 108, 285-287 (2009).
    • (2009) Schizophr. Res , vol.108 , pp. 285-287
    • Brown, A.S.1
  • 15
    • 66949152499 scopus 로고    scopus 로고
    • Prenatal exposure to matern al infection and executive dysfunction in adult schizophrenia
    • Brown, A. S. et al. Prenatal exposure to matern al infection and executive dysfunction in adult schizophrenia. Am. J. Psychiatry 166, 683-690 (2009).
    • (2009) Am. J. Psychiatry , vol.166 , pp. 683-690
    • Brown, A.S.1
  • 16
    • 0033927508 scopus 로고    scopus 로고
    • Identifying critical windows of exposure for children's health
    • Selevan, S. G., Kimmel, C. A. & Mendola, P. Identifying critical windows of exposure for children's health. Environ. Health Perspect. 108 (Suppl. 3), 451-455 (2000).
    • (2000) Environ. Health Perspect , vol.108 , pp. 451-455
    • Selevan, S.G.1    Kimmel, C.A.2    Mendola, P.3
  • 18
    • 79954578712 scopus 로고    scopus 로고
    • Schizophrenia and autism: Both shared and disorder-specific pathogenesis via perinatal inflammation?
    • Meyer, U., Feldon, J. & Dammann, O. Schizophrenia and autism: both shared and disorder-specific pathogenesis via perinatal inflammation? Pediatr. Res. 69, 26R-33R (2011).
    • (2011) Pediatr. Res , vol.69 , pp. 26R-33R
    • Meyer, U.1    Feldon, J.2    Dammann, O.3
  • 20
    • 84885428312 scopus 로고    scopus 로고
    • Fetal glucocorticoid exposure is associated with preadolescent brain development
    • Davis, E. P., Sandman, C. A., Buss, C., Wing, D. A. & Head, K. Fetal glucocorticoid exposure is associated with preadolescent brain development. Biol. Psychiatry 74, 647-655 (2013).
    • (2013) Biol. Psychiatry , vol.74 , pp. 647-655
    • Davis, E.P.1    Sandman, C.A.2    Buss, C.3    Wing, D.A.4    Head, K.5
  • 21
    • 84887312427 scopus 로고    scopus 로고
    • Early-life stress has persistent effects on amygdala function and development in mice and humans
    • Malter Cohen, M. et al. Early-life stress has persistent effects on amygdala function and development in mice and humans. Proc. Natl Acad. Sci. USA 110, 18274-18278 (2013).
    • (2013) Proc. Natl Acad. Sci. USA , vol.110 , pp. 18274-18278
    • Malter Cohen, M.1
  • 22
    • 79958835042 scopus 로고    scopus 로고
    • Sex differences in prenatal epigenetic programming of stress pathways
    • Bale T. L. Sex differences in prenatal epigenetic programming of stress pathways Stress 14, 348-356, 2011).
    • (2011) Stress , vol.14 , pp. 348-356
    • Bale, T.L.1
  • 23
    • 45549101093 scopus 로고    scopus 로고
    • Latent effects of pren atal malnutrition on adult health: The example of schizophrenia
    • Susser, E., St Clair, D. & He, L. Latent effects of pren atal malnutrition on adult health: the example of schizophrenia. Ann. NY Acad. Sci. 1136, 185-192 (2008).
    • (2008) Ann. NY Acad. Sci , vol.1136 , pp. 185-192
    • Susser, E.1    St Clair, D.2    He, L.3
  • 24
    • 84896918827 scopus 로고    scopus 로고
    • Patches of disorganization in the neocortex of children with autism
    • Stoner, R. et al. Patches of disorganization in the neocortex of children with autism. N. Engl. J. Med. 370, 1209-1219 (2014).
    • (2014) N. Engl. J. Med , vol.370 , pp. 1209-1219
    • Stoner, R.1
  • 26
    • 0035224886 scopus 로고    scopus 로고
    • The neurobiology of stress in human pregnancy: Implications for prematurity and development of the fetal central nervous system
    • Wadhwa P. D.,Sandman C. A.,Garite T. J The neurobiology of stress in human pregnancy: implications for prematurity and development of the fetal central nervous system. Prog. Brain Res. 133 131-142 (2001).
    • (2001) Prog. Brain Res , vol.133 , pp. 131-142
    • Wadhwa, P.D.1    Sandman, C.A.2    Garite, T.J.3
  • 27
    • 0027369990 scopus 로고
    • The association between prenatal stress and infant birth weight and gestational age at birth: A prospective investiga tion
    • Wadhwa, P. D., Sandman, C. A., Porto, M., Dunkel-Schetter, C. & Garite, T. J. The association between prenatal stress and infant birth weight and gestational age at birth: a prospective investiga tion. Am. J. Obstet. Gynecol. 169, 858-865 (1993).
    • (1993) Am. J. Obstet. Gynecol , vol.169 , pp. 858-865
    • Wadhwa, P.D.1    Sandman, C.A.2    Porto, M.3    Dunkel-Schetter, C.4    Garite, T.J.5
  • 28
    • 38949120901 scopus 로고    scopus 로고
    • Higher risk of offspring schizophrenia following antenatal maternal exposure to severe adverse life events
    • Khashan, A. S. et al. Higher risk of offspring schizophrenia following antenatal maternal exposure to severe adverse life events. Arch. Gen. Psychiatry 65, 146-152 (2008).
    • (2008) Arch. Gen. Psychiatry , vol.65 , pp. 146-152
    • Khashan, A.S.1
  • 29
    • 77951966593 scopus 로고    scopus 로고
    • Association of hospitalization for infection in childhood with diagnosis of autism spectrum disorders: A danish cohort study
    • Atladottir, H. O. et al. Association of hospitalization for infection in childhood with diagnosis of autism spectrum disorders: a Danish cohort study. Arch. Pediatr. Adolesc. Med. 164, 470-477 (2010).
    • (2010) Arch. Pediatr. Adolesc. Med , vol.164 , pp. 470-477
    • Atladottir, H.O.1
  • 30
    • 78549271649 scopus 로고    scopus 로고
    • Maternal infection requiring hospitalization during pregnancy and autism spectrum disorders
    • Atladottir, H. O. et al. Maternal infection requiring hospitalization during pregnancy and autism spectrum disorders. J. Autism Dev. Disord. 40, 1423-1430 (2010).
    • (2010) J. Autism Dev. Disord , vol.40 , pp. 1423-1430
    • Atladottir, H.O.1
  • 31
    • 84857191889 scopus 로고    scopus 로고
    • Increased midgestational ifn?, il-4 and il-5 in women bearing a child with autism: A case-control study
    • Goines, P. E. et al. Increased midgestational IFN?, IL-4 and IL-5 in women bearing a child with autism: a case-control study. Mol. Autism 2, 13 (2011).
    • (2011) Mol. Autism , vol.2 , pp. 13
    • Goines, P.E.1
  • 32
    • 45549083182 scopus 로고    scopus 로고
    • Prenatal nutritional def iciency and risk of adult schizophrenia
    • Brown, A. S. & Susser, E. S. Prenatal nutritional def iciency and risk of adult schizophrenia. Schizophr. Bull. 34, 1054-1063 (2008).
    • (2008) Schizophr. Bull , vol.34 , pp. 1054-1063
    • Brown, A.S.1    Susser, E.S.2
  • 33
    • 65349105489 scopus 로고    scopus 로고
    • Prenatal malnutrition and adult schizophrenia: Further evidence from the 1959-1961 chinese famine
    • Xu, M. Q. et al. Prenatal malnutrition and adult schizophrenia: further evidence from the 1959-1961 Chinese famine. Schizoph r. Bull. 35, 568-576 (2009).
    • (2009) Schizoph R. Bull , vol.35 , pp. 568-576
    • Xu, M.Q.1
  • 34
    • 0017305263 scopus 로고
    • Obesity in young men after famine exposure in utero and early infancy
    • Ravelli, G. P., Stein, Z. A. & Susser, M. W. Obesity in young men after famine exposure in utero and early infancy. N. Engl. J. Med. 295, 349-353 (1976).
    • (1976) N. Engl. J. Med , vol.295 , pp. 349-353
    • Ravelli, G.P.1    Stein, Z.A.2    Susser, M.W.3
  • 35
    • 55949137722 scopus 로고    scopus 로고
    • Persistent epigenetic differences associated with prenatal exposure to famine in humans
    • Heijmans, B. T. et al. Persistent epigenetic differences associated with prenatal exposure to famine in humans. Proc. Natl Acad. Sci. USA 105, 17046-17049 (2008).
    • (2008) Proc. Natl Acad. Sci. USA , vol.105 , pp. 17046-17049
    • Heijmans, B.T.1
  • 36
    • 79955009389 scopus 로고    scopus 로고
    • Pre-pregnancy and pregnancy obesity and neurodevelopmental outcomes in offspring: A systematic review
    • Van Lieshou t, R. J., Taylor, V. H. & Boyle, M. H. Pre-pregnancy and pregnancy obesity and neurodevelopmental outcomes in offspring: a systematic review. Obes. Rev. 12, e548-e559 (2011).
    • (2011) Obes. Rev , vol.12 , pp. e548-e559
    • Van Lieshou, T.R.J.1    Taylor, V.H.2    Boyle, M.H.3
  • 37
    • 84862506268 scopus 로고    scopus 로고
    • Impaired executive function mediates the association between maternal pre-pregnancy body mass index and child adhd symptoms
    • Buss, C. et al. Impaired executive function mediates the association between maternal pre-pregnancy body mass index and child ADHD symptoms. PLoS ONE 7, e37758 (2012).
    • (2012) PLoS ONE , vol.7 , pp. e37758
    • Buss, C.1
  • 38
    • 84875500069 scopus 로고    scopus 로고
    • O-glcnac transferase (ogt) as a placental biomarker of maternal stress and reprogramming of cns gene transcription in development
    • Howerton, C. L., Morgan, C. P., Fischer, D. B.& Bale, T. L. O-GlcNAc transferase (OGT) as a placental biomarker of maternal stress and reprogramming of CNS gene transcription in development. Proc. Natl Acad. Sci. USA 110, 5169-5174 (2013).
    • (2013) Proc. Natl Acad. Sci. USA , vol.110 , pp. 5169-5174
    • Howerton, C.L.1    Morgan, C.P.2    Fischer, D.B.3    Bale, T.L.4
  • 39
    • 77950439416 scopus 로고    scopus 로고
    • Contrasting effects of different maternal diets on sexually dimorphic gene expression in the murine placenta
    • Mao, J. et al. Contrasting effects of different maternal diets on sexually dimorphic gene expression in the murine placenta. Proc. Natl Acad. Sci. USA 107, 5557-5562 (2010).
    • (2010) Proc. Natl Acad. Sci. USA , vol.107 , pp. 5557-5562
    • Mao, J.1
  • 40
    • 72849132752 scopus 로고    scopus 로고
    • Imprinting and epigenetic changes in the early embryo
    • Weaver, J. R., Susiarjo, M. & Bartolomei, M. S. Imprinting and epigenetic changes in the early embryo. Mamm. Genome 20, 532-543 (2009).
    • (2009) Mamm. Genome , vol.20 , pp. 532-543
    • Weaver, J.R.1    Susiarjo, M.2    Bartolomei, M.S.3
  • 41
    • 33746265587 scopus 로고    scopus 로고
    • Impact of prenatal stress on long term body weight is depende nt on timing and maternal sensitivity
    • Mueller, B. R. & Bale, T. L. Impact of prenatal stress on long term body weight is depende nt on timing and maternal sensitivity. Physiol. Behav. 88, 605-614 (2006).
    • (2006) Physiol. Behav , vol.88 , pp. 605-614
    • Mueller, B.R.1    Bale, T.L.2
  • 42
    • 54049086269 scopus 로고    scopus 로고
    • Sex-specific programming of offspring emotionality after stress early in pregnancy
    • Mueller, B. R. & Bale, T. L. Sex-specific programming of offspring emotionality after stress early in pregnancy. J. Neurosci. 28, 9055-9065 (2008).
    • (2008) J. Neurosci , vol.28 , pp. 9055-9065
    • Mueller, B.R.1    Bale, T.L.2
  • 43
    • 77952516205 scopus 로고    scopus 로고
    • Prenatal social stress in the rat programmes neuroendocrine and behavioural responses to stress in the adult offspring: Sex-specific effects
    • Brunton, P. J. & Russell, J. A. Prenatal social stress in the rat programmes neuroendocrine and behavioural responses to stress in the adult offspring: sex-specific effects. J. Neuroendocrinol. 22, 258-271 (2010).
    • (2010) J. Neuroendocrinol , vol.22 , pp. 258-271
    • Brunton, P.J.1    Russell, J.A.2
  • 44
    • 78650412798 scopus 로고    scopus 로고
    • Allopregnanolone and suppressed hypothalamo-pituitary-Adrenal axis stress responses in late pregnancy in the rat
    • Brunton, P. J. & Russell, J. A. Allopregnanolone and suppressed hypothalamo-pituitary-Adrenal axis stress responses in late pregnancy in the rat. Stress 14, 6-12 (2011).
    • (2011) Stress , vol.14 , pp. 6-12
    • Brunton, P.J.1    Russell, J.A.2
  • 45
    • 34548755195 scopus 로고    scopus 로고
    • Gender difference s in the effects of prenatal stress on brain development and behaviour
    • Weinstock, M. Gender difference s in the effects of prenatal stress on brain development and behaviour. Neurochem. Res. 32, 1730-1740 (2007).
    • (2007) Neurochem. Res , vol.32 , pp. 1730-1740
    • Weinstock, M.1
  • 46
    • 57649233611 scopus 로고    scopus 로고
    • The effects of prenatal stres s on learning in adult offspring is dependent on the timing of the stressor
    • Kapoor, A., Kostaki, A., Janus, C. & Matthews, S. G. The effects of prenatal stres s on learning in adult offspring is dependent on the timing of the stressor. Behav. Brain Res. 197, 144-149 (2009).
    • (2009) Behav. Brain Res , vol.197 , pp. 144-149
    • Kapoor, A.1    Kostaki, A.2    Janus, C.3    Matthews, S.G.4
  • 47
    • 51749115520 scopus 로고    scopus 로고
    • Molecular regulation of the hypothalamic-pituitary-Adrenal axis in adult male guinea pigs after prenatal stress at different stages of gestation
    • Kapoor, A., Leen, J. & Matthews, S. G. Molecular regulation of the hypothalamic-pituitary-Adrenal axis in adult male guinea pigs after prenatal stress at different stages of gestation. J. Physiol. 586, 4317-4326 (2008).
    • (2008) J. Physiol , vol.586 , pp. 4317-4326
    • Kapoor, A.1    Leen, J.2    Matthews, S.G.3
  • 48
    • 0036135988 scopus 로고    scopus 로고
    • The impact of prenatal stress, fetal alcohol exposure, or both on development: Perspectives from a primate model
    • Schneider, M. L., Moore, C. F., Kraemer, G. W., Roberts, A. D. & DeJesus, O. T. The impact of prenatal stress, fetal alcohol exposure, or both on development: perspectives from a primate model. Psychoneuroendocrinology 27, 285-298 (2002).
    • (2002) Psychoneuroendocrinology , vol.27 , pp. 285-298
    • Schneider, M.L.1    Moore, C.F.2    Kraemer, G.W.3    Roberts, A.D.4    Dejesus, O.T.5
  • 49
    • 23744433505 scopus 로고    scopus 로고
    • Short periods of prenatal stress affect growth, behaviour and hypothalamo-pituitary-Adrenal axis activity in male guinea pig offspring
    • Kapoor, A. & Matthews, S. G. Short periods of prenatal stress affect growth, behaviour and hypothalamo-pituitary-Adrenal axis activity in male guinea pig offspring. J. Physiol. 566, 967-977 (2005).
    • (2005) J. Physiol , vol.566 , pp. 967-977
    • Kapoor, A.1    Matthews, S.G.2
  • 50
    • 34247255851 scopus 로고    scopus 로고
    • Early prenatal stress impact on coping strategies and learning performance is sex dependent
    • Mueller, B. R. & Bale, T. L. Early prenatal stress impact on coping strategies and learning performance is sex dependent. Physiol. Behav. 91, 55-65 (2007).
    • (2007) Physiol. Behav , vol.91 , pp. 55-65
    • Mueller, B.R.1    Bale, T.L.2
  • 51
    • 0034718603 scopus 로고    scopus 로고
    • Prenatal stress produces learning deficits associated with an inhibition of neurogenesis in the hippocampus
    • Lemaire, V., Koehl, M., Le Moal, M. & Abrous, D. N. Prenatal stress produces learning deficits associated with an inhibition of neurogenesis in the hippocampus. Proc. Natl Acad. Sci. USA 97, 11032-11037 (2000).
    • (2000) Proc. Natl Acad. Sci. USA , vol.97 , pp. 11032-11037
    • Lemaire, V.1    Koehl, M.2    Le Moal, M.3    Abrous, D.N.4
  • 52
    • 40849124149 scopus 로고    scopus 로고
    • Epigenetic programming of the stress response in male and female rats by prenatal restraint stress
    • Darnaudery, M. & Maccari, S. Epigenetic programming of the stress response in male and female rats by prenatal restraint stress. Brain Res. Rev. 57, 571-585 (2008).
    • (2008) Brain Res. Rev , vol.57 , pp. 571-585
    • Darnaudery, M.1    Maccari, S.2
  • 53
    • 0034749488 scopus 로고    scopus 로고
    • Alterations induced by gestational stress in brain morphology and behaviour of the offspring
    • Weinstock, M. Alterations induced by gestational stress in brain morphology and behaviour of the offspring. Prog. Neurobiol. 65, 427-451 (2001).
    • (2001) Prog. Neurobiol , vol.65 , pp. 427-451
    • Weinstock, M.1
  • 54
    • 0242391948 scopus 로고    scopus 로고
    • Prenatal stress diminishes neurogenesis in the dentate gyrus of juvenile rhesus monkeys
    • Coe, C. L. et al. Prenatal stress diminishes neurogenesis in the dentate gyrus of juvenile rhesus monkeys. Biol. Psych iatry 54, 1025-1034 (2003).
    • (2003) Biol. Psych Iatry , vol.54 , pp. 1025-1034
    • Coe, C.L.1
  • 55
    • 0035836457 scopus 로고    scopus 로고
    • Prenatal glucocorticoid programming of brain corticosteroid receptors and corticotrophin-releasing hormone: Possible implic ations for behaviour
    • Welberg, L. A., Seckl, J. R. & Holmes, M. C. Prenatal glucocorticoid programming of brain corticosteroid receptors and corticotrophin-releasing hormone: possible implic ations for behaviour. Neuroscience 104, 71-79 (2001).
    • (2001) Neuroscience , vol.104 , pp. 71-79
    • Welberg, L.A.1    Seckl, J.R.2    Holmes, M.C.3
  • 56
    • 0035180462 scopus 로고    scopus 로고
    • Prenatal stress, glucocorticoids and the programming of the brain
    • Welberg, L. A. & Seckl, J. R. Prenatal stress, glucocorticoids and the programming of the brain. J. Neuroendocrinol. 13, 113-128 (2001).
    • (2001) J. Neuroendocrinol , vol.13 , pp. 113-128
    • Welberg, L.A.1    Seckl, J.R.2
  • 57
    • 0015496412 scopus 로고
    • Prenatal stress femin izes and demasculinizes the behavior of males
    • Ward, I. L. Prenatal stress femin izes and demasculinizes the behavior of males. Science 175, 82-84 (1972).
    • (1972) Science , vol.175 , pp. 82-84
    • Ward, I.L.1
  • 58
    • 0025940893 scopus 로고
    • Prenatal stress feminizes juvenile play patterns in male rats
    • Ward, I. L. & Stehm, K. E. Prenatal stress feminizes juvenile play patterns in male rats. Physiol. Behav. 50, 601-605 (1991).
    • (1991) Physiol. Behav , vol.50 , pp. 601-605
    • Ward, I.L.1    Stehm, K.E.2
  • 59
    • 84924743530 scopus 로고    scopus 로고
    • Elevated fetal steroidogenic activity in autism
    • Baron-Cohen, S. et al. Elevated fetal steroidogenic activity in autism. Mol. Psychiatry 20, 369-376 (2015).
    • (2015) Mol. Psychiatry , vol.20 , pp. 369-376
    • Baron-Cohen, S.1
  • 60
    • 84883656165 scopus 로고    scopus 로고
    • Serum test osterone levels are related to cognitive function in men with schizophrenia
    • Moore, L. et al. Serum test osterone levels are related to cognitive function in men with schizophrenia. Psychoneuroendocrinology 38, 1717-1728 (2013).
    • (2013) Psychoneuroendocrinology , vol.38 , pp. 1717-1728
    • Moore, L.1
  • 61
    • 84855669393 scopus 로고    scopus 로고
    • Fetal testosterone influences sexually dimorp hic gray matter in the human brain
    • Lombardo, M. V. et al. Fetal testosterone influences sexually dimorp hic gray matter in the human brain. J. Neurosci. 32, 674-680 (2012).
    • (2012) J. Neurosci , vol.32 , pp. 674-680
    • Lombardo, M.V.1
  • 62
    • 1542408463 scopus 로고    scopus 로고
    • A sexually dimorphic ratio of orbitofrontal to amygdala volume is altered in schizophrenia
    • Gur, R. E. et al. A sexually dimorphic ratio of orbitofrontal to amygdala volume is altered in schizophrenia. Biol. Psychiatry 55, 512-517 (2004).
    • (2004) Biol. Psychiatry , vol.55 , pp. 512-517
    • Gur, R.E.1
  • 63
    • 23844485616 scopus 로고    scopus 로고
    • Enduring, handling-evoked enhancement of hippocampal memory function and glucocorticoid receptor expression involves activation of the corticotropin-releasing factor type 1 receptor
    • Fenoglio, K. A. et al. Enduring, handling-evoked enhancement of hippocampal memory function and glucocorticoid receptor expression involves activation of the corticotropin-releasing factor type 1 receptor. Endocrinology 146, 4090-4096 (2005).
    • (2005) Endocrinology , vol.146 , pp. 4090-4096
    • Fenoglio, K.A.1
  • 64
    • 33745345179 scopus 로고    scopus 로고
    • Hippocampal neuroplasticity induced by early-life stress: Functional and molecular aspects
    • Fenoglio K. A.,Brunson K. L.,Baram T. Z Hippocampal neuroplasticity induced by early-life stress: functional and molecular aspects. Front. Neuroendocrinol. 27 180-192, 2006).
    • (2006) Front. Neuroendocrinol , vol.27 , pp. 180-192
    • Fenoglio, K.A.1    Brunson, K.L.2    Baram, T.Z.3
  • 65
    • 46549086320 scopus 로고    scopus 로고
    • Dysfunctional nurturing behavior in rat dams with limited access to nesting material: A clinically relevant model for early-life stress
    • I vy, A. S., Brunson, K. L., Sandman, C. & Baram, T. Z. Dysfunctional nurturing behavior in rat dams with limited access to nesting material: a clinically relevant model for early-life stress. Neuroscience 154, 1132-114 2 (2008).
    • (2008) Neuroscience , vol.154 , pp. 1132-1142
    • Ivy, A.S.1    Brunson, K.L.2    Sandman, C.3    Baram, T.Z.4
  • 66
    • 77957355154 scopus 로고    scopus 로고
    • Hippocampal dysfunction and cognitive impairments provoked by chronic early-life stress involve excessive activation of crh receptors
    • Ivy, A. S. et al. Hippocampal dysfunction and cognitive impairments provoked by chronic early-life stress involve excessive activation of CRH receptors. J. Neurosci. 30, 13005-13015 (2010).
    • (2010) J. Neurosci , vol.30 , pp. 13005-13015
    • Ivy, A.S.1
  • 67
    • 77958525984 scopus 로고    scopus 로고
    • Plasticity of the stress response early in life: Mechanisms and significance
    • Korosi, A. & Baram, T. Z. Plasticity of the stress response early in life: mechanisms and significance. Dev. Psychobiol. 52, 661-670 (2010).
    • (2010) Dev. Psychobiol , vol.52 , pp. 661-670
    • Korosi, A.1    Baram, T.Z.2
  • 68
    • 74949108078 scopus 로고    scopus 로고
    • Early-life experience reduces excitation to stress-responsive hypothalamic neurons and reprograms the expression of corticotropin-releasing hormone
    • Korosi, A. et al. Early-life experience reduces excitation to stress-responsive hypothalamic neurons and reprograms the expression of corticotropin-releasing hormone. J. Neurosci. 30, 703-713 (2010).
    • (2010) J. Neurosci , vol.30 , pp. 703-713
    • Korosi, A.1
  • 69
    • 79958014482 scopus 로고    scopus 로고
    • Emerging roles of epigenetic mechanisms in the enduring effects of early-life stress and experience on learning and memory
    • McClel land, S., Korosi, A., Cope, J., Ivy, A. & Baram, T. Z. Emerging roles of epigenetic mechanisms in the enduring effects of early-life stress and experience on learning and memory. Neurobiol. Learn. Mem. 96, 79-88 (2011).
    • (2011) Neurobiol. Learn. Mem , vol.96 , pp. 79-88
    • McClel Land, S.1    Korosi, A.2    Cope, J.3    Ivy, A.4    Baram, T.Z.5
  • 70
    • 53249109683 scopus 로고    scopus 로고
    • A novel mouse model for acute and long-lasting consequences of early life stress
    • Rice, C. J., Sandman, C. A., Lenjavi, M. R. & Baram, T. Z. A novel mouse model for acute and long-lasting consequences of early life stress. Endocrinology 149, 4892-4900 (2008).
    • (2008) Endocrinology , vol.149 , pp. 4892-4900
    • Rice, C.J.1    Sandman, C.A.2    Lenjavi, M.R.3    Baram, T.Z.4
  • 71
    • 0034000440 scopus 로고    scopus 로고
    • Long-term behavioral and neuroendocrine adaptations to adverse early experience
    • Ladd, C. O. et al. Long-term behavioral and neuroendocrine adaptations to adverse early experience. Prog. Brain Res. 122, 81-103 (2000).
    • (2000) Prog. Brain Res , vol.122 , pp. 81-103
    • Ladd, C.O.1
  • 72
    • 15144344289 scopus 로고    scopus 로고
    • Maternal care, hippocampal glucocorticoid receptors, and hypothalamic-pituitary-Adrenal responses to stress
    • Liu, D. et al. Maternal care, hippocampal glucocorticoid receptors, and hypothalamic-pituitary-Adrenal responses to stress. Science 277, 1659-1662 (1997).
    • (1997) Science , vol.277 , pp. 1659-1662
    • Liu, D.1
  • 73
    • 0034928759 scopus 로고    scopus 로고
    • Maternal care, gene expression, and the transmi ssion of individual differences in stress reactivity across generations
    • Meaney, M. J. Maternal care, gene expression, and the transmi ssion of individual differences in stress reactivity across generations. Annu. Rev. Neurosci. 24, 1161-1192 (2001).
    • (2001) Annu. Rev. Neurosci , vol.24 , pp. 1161-1192
    • Meaney, M.J.1
  • 74
    • 3342989681 scopus 로고    scopus 로고
    • Epigenetic programming by maternal behavior
    • Weaver, I. C. et al. Epigenetic programming by maternal behavior. Nature Neurosci. 7, 847-854 (2004).
    • (2004) Nature Neurosci , vol.7 , pp. 847-854
    • Weaver, I.C.1
  • 75
    • 36048945364 scopus 로고    scopus 로고
    • Maternal care affects male and female offspring working memory and stress reactivity
    • Barha, C. K., Pawluski, J. L. & Galea, L. A. Maternal care affects male and female offspring working memory and stress reactivity. Physiol. Behav. 92, 939-950 (2 007).
    • (2007) Physiol. Behav , vol.92 , pp. 939-950
    • Barha, C.K.1    Pawluski, J.L.2    Galea, L.A.3
  • 76
    • 0035354549 scopus 로고    scopus 로고
    • Early adverse experience as a developmental risk factor for later psychopathology: Evidence from rodent and primate models
    • Sanchez, M. M., Ladd, C. O. & Plotsky, P. M. Early adverse experience as a developmental risk factor for later psychopathology: evidence from rodent and primate models. Dev. Psychopathol. 13, 41 9-449 (2001).
    • (2001) Dev. Psychopathol , vol.13 , pp. 419-449
    • Sanchez, M.M.1    Ladd, C.O.2    Plotsky, P.M.3
  • 77
    • 0032574785 scopus 로고    scopus 로고
    • Maternal care during infancy regulates the development of neural systems mediating the expression of fearfulness in the rat
    • Caldji, C. et al. Maternal care during infancy regulates the development of neural systems mediating the expression of fearfulness in the rat. Proc. Natl Acad. Sci. USA 95, 5335-5340 (19 98).
    • (1998) Proc. Natl Acad. Sci. USA , vol.95 , pp. 5335-5340
    • Caldji, C.1
  • 78
    • 3042747515 scopus 로고    scopus 로고
    • Early environmental regulation of hippocampal glucocorticoid receptor gene expression: Characterization of intracellular mediators an d potential genomic target sites
    • Weaver, I. C., Diorio, J., Seckl, J. R., Szyf, M. & Meaney, M. J. Early environmental regulation of hippocampal glucocorticoid receptor gene expression: characterization of intracellular mediators an d potential genomic target sites. Ann. NY Acad. Sci. 1024, 182-212 (2004).
    • (2004) Ann. NY Acad. Sci , vol.1024 , pp. 182-212
    • Weaver, I.C.1    Diorio, J.2    Seckl, J.R.3    Szyf, M.4    Meaney, M.J.5
  • 79
    • 77952242328 scopus 로고    scopus 로고
    • The pathways from mother's love to baby's future
    • Korosi, A. & Baram, T. Z. The pathways from mother's love to baby's future. Front. Behav. Neurosci. 3, 27 (20 09).
    • (2009) Front. Behav. Neurosci , vol.3 , pp. 27
    • Korosi, A.1    Baram, T.Z.2
  • 80
    • 0033149125 scopus 로고    scopus 로고
    • The effects of neonatal stress on brain development: Implications for psychopathology
    • Graham, Y. P., Heim, C., Goodman, S. H., Miller, A. H. & Nemeroff, C. B. The effects of neonatal stress on brain development: implications for psychopathology. Dev. Psychopathol. 11, 545-565 (1999).
    • (1999) Dev. Psychopathol , vol.11 , pp. 545-565
    • Graham, Y.P.1    Heim, C.2    Goodman, S.H.3    Miller, A.H.4    Nemeroff, C.B.5
  • 81
    • 0033385116 scopus 로고    scopus 로고
    • Postnatal experiences and genetic effects on squirrel monkey social affinities and emotional distress
    • Lyons, D. M., Martel, F. L., Levine, S., Risch, N. J. & Schatzberg, A. F. Postnatal experiences and genetic effects on squirrel monkey social affinities and emotional distress. Horm. Behav.36, 266-275 (1999).
    • (1999) Horm. Behav , vol.36 , pp. 266-275
    • Lyons, D.M.1    Martel, F.L.2    Levine, S.3    Risch, N.J.4    Schatzberg, A.F.5
  • 82
    • 4344607104 scopus 로고    scopus 로고
    • Sexual dichotomy of an interaction between early adversity and the serotonin transporter gene promoter variant in rhesus macaques
    • Barr, C. S. et al. Sexual dichotomy of an interaction between early adversity and the serotonin transporter gene promoter variant in rhesus macaques. Proc. Natl Acad. Sci. USA 1 01, 12358-12363 (2004).
    • (2004) Proc. Natl Acad. Sci. USA , vol.101 , pp. 12358-12363
    • Barr, C.S.1
  • 83
    • 60749105468 scopus 로고    scopus 로고
    • Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse
    • McGowan, P. O. et al. Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse. Nature Neurosci. 12, 342-348 (2009).
    • (2009) Nature Neurosci , vol.12 , pp. 342-348
    • McGowan, P.O.1
  • 84
    • 84905020692 scopus 로고    scopus 로고
    • Epigenetic modification of the glucocorticoid receptor gene is linked to traumatic memory and post-traumatic stress disorder risk in genocide survivors
    • Vukojevic, V. et al. Epigenetic modification of the glucocorticoid receptor gene is linked to traumatic memory and post-traumatic stress disorder risk in genocide survivors. J. Neurosci. 34, 10274-10284 (2014).
    • (2014) J. Neurosci , vol.34 , pp. 10274-10284
    • Vukojevic, V.1
  • 85
    • 0016727590 scopus 로고
    • The influence of protein restriction imposed at various stages of pregnancy on fetal and placental development
    • Koshy, T. S., Sara, V. R., King, T. L. & Lazarus, L. The influence of protein restriction imposed at various stages of pregnancy on fetal and placental development. Growth 39, 497-506 (1975).
    • (1975) Growth , vol.39 , pp. 497-506
    • Koshy, T.S.1    Sara, V.R.2    King, T.L.3    Lazarus, L.4
  • 86
    • 77952879211 scopus 로고    scopus 로고
    • Early life protein restriction alters dopamine circuitry
    • Vucetic, Z. et al. Early life protein restriction alters dopamine circuitry. Neuroscience 168, 359-370 (2010).
    • (2010) Neuroscience , vol.168 , pp. 359-370
    • Vucetic, Z.1
  • 87
    • 78649747523 scopus 로고    scopus 로고
    • Caloric restriction experience reprograms stress and orexigenic pathways and promotes binge eating
    • Pankevich, D. E., Teegarden, S. L., Hedin, A. D., Jensen, C. L. & Bale, T. L. Caloric restriction experience reprograms stress and orexigenic pathways and promotes binge eating. J. Neurosci. 30, 16399-16407 (2010).
    • (2010) J. Neurosci , vol.30 , pp. 16399-16407
    • Pankevich, D.E.1    Teegarden, S.L.2    Hedin, A.D.3    Jensen, C.L.4    Bale, T.L.5
  • 88
    • 34047263811 scopus 로고    scopus 로고
    • Decreases in dietary preference produce increased emotionality and risk for dietary relapse
    • Teegarden S. L.,Bale T. L. Decreases in dietary preference produce increased emotionality and risk for dietary relapse Biol. Psychiatry 61, 1021-1029, 2007).
    • (2007) Biol. Psychiatry , vol.61 , pp. 1021-1029
    • Teegarden, S.L.1    Bale, T.L.2
  • 89
    • 40749134927 scopus 로고    scopus 로고
    • Effects of stress on dietary preference and intake are dependent on access and stress sensitivity
    • Teegarden, S. L.& Bale, T. L. Effects of stress on dietary preference and intake are dependent on access and stress sensitivity. Physiol. Behav. 93, 713-723 (2008).
    • (2008) Physiol. Behav , vol.93 , pp. 713-723
    • Teegarden, S.L.1    Bale, T.L.2
  • 90
    • 68049121848 scopus 로고    scopus 로고
    • Early life exposure to a high fat diet promotes long-term changes in dietary preferences and central reward signaling
    • Teegarden, S. L., Scott, A. N. & Bale , T. L. Early life exposure to a high fat diet promotes long-term changes in dietary preferences and central reward signaling. Neuroscience 162, 924-932 (2009).
    • (2009) Neuroscience , vol.162 , pp. 924-932
    • Teegarden, S.L.1    Scott, A.N.2    Bale, T.L.3
  • 91
    • 0037390212 scopus 로고    scopus 로고
    • Nucleus accumbens ?-opioids regulate intake of a high-fat diet via activation of a distributed brain network
    • Will, M. J., Franzblau, E. B. & Kelley, A. E. Nucleus accumbens ?-opioids regulate intake of a high-fat diet via activation of a distributed brain network. J. Neurosci. 23, 2882-2888 (2003).
    • (2003) J. Neurosci , vol.23 , pp. 2882-2888
    • Will, M.J.1    Franzblau, E.B.2    Kelley, A.E.3
  • 92
    • 0142250829 scopus 로고    scopus 로고
    • Hyperdopaminergic mutant mice have higher " wanting" but not "liking" for sweet rewards
    • Pecina, S., Cagniard, B., Berridge , K. C., Aldridge, J. W. & Zhuang, X. Hyperdopaminergic mutant mice have higher " wanting" but not "liking" for sweet rewards. J. Neurosci. 23, 9395-9402 (2003).
    • (2003) J. Neurosci , vol.23 , pp. 9395-9402
    • Pecina, S.1    Cagniard, B.2    Berridge, K.C.3    Aldridge, J.W.4    Zhuang, X.5
  • 93
    • 84860904832 scopus 로고    scopus 로고
    • Reconciling the nutritional and glucocorticoid hypotheses of fetal programming
    • Cottrell, E. C., Holmes, M.C., Livingstone, D. E., Kenyon, C. J. & Seckl, J. R. Reconciling the nutritional and glucocorticoid hypotheses of fetal programming. FASEB J. 26, 1866-1874 (2012).
    • (2012) FASEB J , vol.26 , pp. 1866-1874
    • Cottrell, E.C.1    Holmes, M.C.2    Livingstone, D.E.3    Kenyon, C.J.4    Seckl, J.R.5
  • 94
    • 0035047054 scopus 로고    scopus 로고
    • Maternal undernutrition during late gestation induces fetal overexposure to glucocorticoids and intrauterine growth retardation, and disturbs the hypothalamo-pituitary-Adrenal axis in the newborn rat
    • Lesage, J., Blondeau, B., Grino, M., Breant, B. & Dupouy, J. P. Maternal undernutrition during late gestation induces fetal overexposure to glucocorticoids and intrauterine growth retardation, and disturbs the hypothalamo-pituitary-Adrenal axis in the newborn rat. Endocrinology 142, 1692-1702 (2001).
    • (2001) Endocrinology , vol.142 , pp. 1692-1702
    • Lesage, J.1    Blondeau, B.2    Grino, M.3    Breant, B.4    Dupouy, J.P.5
  • 95
    • 0032752554 scopus 로고    scopus 로고
    • Maternal nutrient restriction (48 h) modifies brain corticost eroid receptor expression and endocrine function in the fetal guinea pig
    • Lingas, R., Dean, F. & Matthews, S. G. Maternal nutrient restriction (48 h) modifies brain corticost eroid receptor expression and endocrine function in the fetal guinea pig. Brain Res. 846, 236-242 (1999).
    • (1999) Brain Res , vol.846 , pp. 236-242
    • Lingas, R.1    Dean, F.2    Matthews, S.G.3
  • 96
    • 77953322844 scopus 로고    scopus 로고
    • Prenatal stress, glucocorticoids and the programming of ad ult disease
    • Cottrell, E. C. & Seckl, J. R. Prenatal stress, glucocorticoids and the programming of ad ult disease. Front. Behav. Neurosci. 3, 19 (2009).
    • (2009) Front. Behav. Neurosci , vol.3 , pp. 19
    • Cottrell, E.C.1    Seckl, J.R.2
  • 97
    • 34249316880 scopus 로고    scopus 로고
    • Mechanisms of disease: Glucocorticoids their placental metabolism and fetal 'programming ' of adult pathophysiology
    • Seckl, J. R. & Holmes, M. C. Mechanisms of disease: glucocorticoids, their placental metabolism and fetal 'programming ' of adult pathophysiology.Nature Clin. Pract. Endocrinol. Metab. 3, 479-488 (2007).
    • (2007) Nature Clin. Pract. Endocrinol. Metab , vol.3 , pp. 479-488
    • Seckl, J.R.1    Holmes, M.C.2
  • 98
    • 26044475876 scopus 로고    scopus 로고
    • Chronic maternal stress inhibits the capacity to up-regulate pl acental 11?-hydroxysteroid dehydrogenase type 2 activity
    • Welberg, L. A., Thrivikraman, K. V. & Plotsky, P. M. Chronic maternal stress inhibits the capacity to up-regulate pl acental 11?-hydroxysteroid dehydrogenase type 2 activity. J. Endocrinol. 186, R7-R12 (2005).
    • (2005) J. Endocrinol , vol.186 , pp. R7-R12
    • Welberg, L.A.1    Thrivikraman, K.V.2    Plotsky, P.M.3
  • 99
    • 77950216899 scopus 로고    scopus 로고
    • Changes in melanocortin expression and inflammatory pathways in fetal offspring of n onhuman primates fed a high-fat diet
    • Grayson, B. E. et al. Changes in melanocortin expression and inflammatory pathways in fetal offspring of n onhuman primates fed a high-fat diet. Endocrinology 151, 1622-1632 (2010).
    • (2010) Endocrinology , vol.151 , pp. 1622-1632
    • Grayson, B.E.1
  • 100
    • 77949366451 scopus 로고    scopus 로고
    • Chronic consumption of a high-fat diet during pregnancy causes perturbations in the serotoner gic system and increased anxiety-like behavior in nonhuman primate offspring
    • Sullivan, E. L. et al. Chronic consumption of a high-fat diet during pregnancy causes perturbations in the serotoner gic system and increased anxiety-like behavior in nonhuman primate offspring. J. Neurosci. 30, 3826-3830 (2010).
    • (2010) J. Neurosci , vol.30 , pp. 3826-3830
    • Sullivan, E.L.1
  • 101
    • 77953521826 scopus 로고    scopus 로고
    • Enduring consequences of maternal obesity for bra in inflammation and behavior of offspring
    • Bilbo, S. D. & Tsang, V. Enduring consequences of maternal obesity for bra in inflammation and behavior of offspring. FASEB J. 24, 2104-2115 (2010).
    • (2010) FASEB J , vol.24 , pp. 2104-2115
    • Bilbo, S.D.1    Tsang, V.2
  • 102
    • 79956314891 scopus 로고    scopus 로고
    • Maternal high-fat diet disturbs uteroplacental hemodynamics and increases the frequency of stillb irth in a nonhuman primate model of excess nutrition
    • Frias, A. E. et al. Maternal high-fat diet disturbs uteroplacental hemodynamics and increases the frequency of stillb irth in a nonhuman primate model of excess nutrition. Endocrinology 152, 2456-2464 (2011).
    • (2011) Endocrinology , vol.152 , pp. 2456-2464
    • Frias, A.E.1
  • 103
    • 39149119959 scopus 로고    scopus 로고
    • The role of pro-inflammatory factors in mediating the effects on the fetus of prenat al undernutrition: Implications for schizophrenia
    • Shen, Q. et al. The role of pro-inflammatory factors in mediating the effects on the fetus of prenat al undernutrition: implications for schizophrenia. Schizophr. Res. 99, 48-55 (2008).
    • (2008) Schizophr. Res , vol.99 , pp. 48-55
    • Shen, Q.1
  • 104
    • 34648823296 scopus 로고    scopus 로고
    • Activation of toll-like receptors 2 or 3 and preterm delivery in the mous e
    • Ilievski, V., Lu, S. J. & Hirsch, E. Activation of toll-like receptors 2 or 3 and preterm delivery in the mous e. Reprod. Sci. 14, 315-320 (2007).
    • (2007) Reprod. Sci , vol.14 , pp. 315-320
    • Ilievski, V.1    Lu, S.J.2    Hirsch, E.3
  • 105
    • 84865836058 scopus 로고    scopus 로고
    • Placental regulation of maternal-fetal interactions and brain development
    • Hsiao, E. Y. & Patterson, P. H. Placental regulation of maternal-fetal interactions and brain development. Dev. Neurobiol. 72,1317-1326 (2012).
    • (2012) Dev. Neurobiol , vol.72 , pp. 1317-1326
    • Hsiao, E.Y.1    Patterson, P.H.2
  • 106
    • 84858740384 scopus 로고    scopus 로고
    • Maternal immune activation yields offspring displaying mouse versions of the three core symptoms of autism
    • Malkova, N. V., Yu, C. Z., Hsiao, E. Y., Moore, M. J. & Patterson, P. H. Maternal immune activation yields offspring displaying mouse versions of the three core symptoms of autism. Brain Behav. Immun.26, 607-616 (2012).
    • (2012) Brain Behav. Immun , vol.26 , pp. 607-616
    • Malkova, N.V.1    Yu, C.Z.2    Hsiao, E.Y.3    Moore, M.J.4    Patterson, P.H.5
  • 107
    • 77649139342 scopus 로고    scopus 로고
    • Early-life programming of later-life brain and behavior: A critical role for the immune system
    • Bilbo, S. D. & Schwarz, J. M. Early-life programming of later-life brain and behavior: a critical role for the immune system. Front. Behav. Neurosci. 3, 14 (2009).
    • (2009) Front. Behav. Neurosci , vol.3 , pp. 14
    • Bilbo, S.D.1    Schwarz, J.M.2
  • 108
    • 84903287131 scopus 로고    scopus 로고
    • Prenatal stress-induced increases in placental inflammation and offspring hyperactivity are male-specific and ameliorated by maternal antiinflammatory treatment
    • Bronson, S. L. & Bale, T. L. Prenatal stress-induced increases in placental inflammation and offspring hyperactivity are male-specific and ameliorated by maternal antiinflammatory treatment. Endocrino logy 155, 2635-2646 (2014).
    • (2014) Endocrino Logy , vol.155 , pp. 2635-2646
    • Bronson, S.L.1    Bale, T.L.2
  • 109
    • 79954718560 scopus 로고    scopus 로고
    • Activation of the maternal immune system induces endocrine changes in the placenta via il-6
    • Hsiao, E. Y. & Patterson, P. H. Activation of the maternal immune system induces endocrine changes in the placenta via IL-6. Brain Behav. Immun. 25, 604-615 (2011).
    • (2011) Brain Behav. Immun , vol.25 , pp. 604-615
    • Hsiao, E.Y.1    Patterson, P.H.2
  • 110
    • 58149125303 scopus 로고    scopus 로고
    • Prenatal stress reduces postnatal neurogenesis in rats selectively bred for high, but not low, anxiety: Possible key role of placental 11?-hydroxysteroid dehydrogenase type 2
    • Lucassen, P. J. et al. Prenatal stress reduces postnatal neurogenesis in rats selectively bred for high, but not low, anxiety: possible key role of placental 11?-hydroxysteroid dehydrogenase type 2. Eur. J. Neurosci. 29, 97-103 (2009).
    • (2009) Eur. J. Neurosci , vol.29 , pp. 97-103
    • Lucassen, P.J.1
  • 111
    • 34447555960 scopus 로고    scopus 로고
    • Maternal stress alters endocrine function of the feto-placental unit in rats
    • Mairesse, J. et al. Maternal stress alters endocrine function of the feto-placental unit in rats. Am. J. Physiol. Endocrinol. Metab. 292, E1526-E1533 (2007).
    • (2007) Am. J. Physiol. Endocrinol. Metab , vol.292 , pp. E1526-E1533
    • Mairesse, J.1
  • 112
    • 84859624500 scopus 로고    scopus 로고
    • Effects of maternal immune activation on gene expression patterns in the fetal brain
    • Garbett, K. A., Hsiao, E. Y., Kalman, S., Patterson, P. H. & Mirnics, K. Effects of maternal immune activation on gene expression patterns in the fetal brain. Transl. Psychiatry 2, e98 (2012).
    • (2012) Transl. Psychiatry , vol.2 , pp. e98
    • Garbett, K.A.1    Hsiao, E.Y.2    Kalman, S.3    Patterson, P.H.4    Mirnics, K.5
  • 113
    • 0035955640 scopus 로고    scopus 로고
    • Interleukin-6 regulation of the human dna methyltransferase (hdnmt) gene in human erythroleukemia cells
    • Hodge, D. R. et al. Interleukin-6 regulation of the human DNA methyltransferase (HDNMT) gene in human erythroleukemia cells. J. Biol. Chem. 276, 39508-39511 (2001).
    • (2001) J. Biol. Chem , vol.276 , pp. 39508-39511
    • Hodge, D.R.1
  • 114
    • 84903721712 scopus 로고    scopus 로고
    • Targeted placental deletion of ogt recapitulates the prenatal stress phenotype including hypothalamic mitochondrial dysfunction
    • Howerton, C. L. & Bale, T. L. Targeted placental deletion of OGT recapitulates the prenatal stress phenotype including hypothalamic mitochondrial dysfunction. Proc. Natl Acad. Sci. USA 111, 9639-9644 (2014).
    • (2014) Proc. Natl Acad. Sci. USA , vol.111 , pp. 9639-9644
    • Howerton, C.L.1    Bale, T.L.2
  • 115
    • 79952693631 scopus 로고    scopus 로고
    • Sex-specificity in transgenerational epigenetic programming
    • Dunn, G. A., Morgan, C. P. & Bale, T. L. Sex-specificity in transgenerational epigenetic programming. Horm. Behav. 59, 290-295 (2011).
    • (2011) Horm. Behav , vol.59 , pp. 290-295
    • Dunn, G.A.1    Morgan, C.P.2    Bale, T.L.3
  • 116
    • 31344434726 scopus 로고    scopus 로고
    • Sex-specific, ma le-line transgenerational responses in humans
    • Pembrey, M. E. et al. Sex-specific, ma le-line transgenerational responses in humans. Eur. J. Hum. Genet. 14, 159-166 (2006).
    • (2006) Eur. J. Hum. Genet , vol.14 , pp. 159-166
    • Pembrey, M.E.1
  • 117
    • 0036862451 scopus 로고    scopus 로고
    • Cardiovascular and diabetes mortality determined by nutrition durin g parents' and grandparents' slow growth period
    • Kaati, G., Bygren, L. O. & Edvinsson, S. Cardiovascular and diabetes mortality determined by nutrition durin g parents' and grandparents' slow growth period. Eur. J. Hum. Genet. 10, 682-688 (2002).
    • (2002) Eur. J. Hum. Genet , vol.10 , pp. 682-688
    • Kaati, G.1    Bygren, L.O.2    Edvinsson, S.3
  • 118
    • 84907101993 scopus 로고    scopus 로고
    • Human transgenerational responses to early-life experience: Poten tial impact on development, health and biomedical research
    • Pembrey, M., Saffery, R. & Bygren, L. O. Human transgenerational responses to early-life experience: poten tial impact on development, health and biomedical research. J. Med. Genet. 51, 563-572 (2014).
    • (2014) J. Med. Genet , vol.51 , pp. 563-572
    • Pembrey, M.1    Saffery, R.2    Bygren, L.O.3
  • 119
    • 80051724610 scopus 로고    scopus 로고
    • Early prenatal stress epigenetically programs dysmasculinization in s econd-generation offspring via the paternal lineage
    • Morgan, C. P. & Bale, T. L. Early prenatal stress epigenetically programs dysmasculinization in s econd-generation offspring via the paternal lineage. J. Neurosci. 31, 11748-11755 (2011).
    • (2011) J. Neurosci , vol.31 , pp. 11748-11755
    • Morgan, C.P.1    Bale, T.L.2
  • 120
    • 77955654186 scopus 로고    scopus 로고
    • Epigenetic transmission of the impact of early stress across generations
    • Franklin, T. B. et al. Epigenetic transmission of the impact of early stress across generations. Biol. Psychiatry 68, 408-415 (2010).
    • (2010) Biol. Psychiatry , vol.68 , pp. 408-415
    • Franklin, T.B.1
  • 121
    • 84879303635 scopus 로고    scopus 로고
    • Maternal obesity has little effect on the immediate offspring but impacts on the next generation
    • King, V. et al. Maternal obesity has little effect on the immediate offspring but impacts on the next generation. Endocrinology 154, 2514-2524 (2013).
    • (2013) Endocrinology , vol.154 , pp. 2514-2524
    • King, V.1
  • 122
    • 70350313230 scopus 로고    scopus 로고
    • Maternal high-fat diet promotes body length increases and insulin insensitivity in second-generation mice
    • Dunn, G. A. & Bale, T. L. Maternal high-fat diet promotes body length increases and insulin insensitivity in second-generation mice. Endocrinology 150, 4999-5009 (2009) .
    • (2009) Endocrinology , vol.150 , pp. 4999-5009
    • Dunn, G.A.1    Bale, T.L.2
  • 123
    • 79956301666 scopus 로고    scopus 로고
    • Maternal high-fat diet effects on third-generation female body size via the paternal lineage
    • Dunn, G. A. & Bale, T. L. Maternal high-fat diet effects on third-generation female body size via the paternal lineage. Endocrinology 152, 2228-2236 (2011).
    • (2011) Endocrinology , vol.152 , pp. 2228-2236
    • Dunn, G.A.1    Bale, T.L.2
  • 124
    • 63249089823 scopus 로고    scopus 로고
    • Intergenerational transmission of glucose intolerance and obesity by in utero undernutrition in mice
    • Jimenez-Chillaron, J. C. et al. Intergenerational transmission of glucose intolerance and obesity by in utero undernutrition in mice. Diabetes 58, 460-468 (2009).
    • (2009) Diabetes , vol.58 , pp. 460-468
    • Jimenez-Chillaron, J.C.1
  • 125
    • 34247559733 scopus 로고    scopus 로고
    • Tra nsgenerational inheritance of the insulin-resistant phenotype in embryo-transferred intrauterine growth-restricted adult female rat offspring
    • Thamotharan, M. et al. Tra nsgenerational inheritance of the insulin-resistant phenotype in embryo-transferred intrauterine growth-restricted adult female rat offspring. Am. J. Physiol. Endocrinol. Metab. 292, E1270-E1279 (2007).
    • (2007) Am. J. Physiol. Endocrinol. Metab , vol.292 , pp. E1270-E1279
    • Thamotharan, M.1
  • 126
    • 34047258298 scopus 로고    scopus 로고
    • Dietary protein restriction of pregnant rats in the f0 generation induces altered methylation of hepatic gene promoters in the adult male offspring in the f1 and f2 generations
    • Burdge, G. C. et al. Dietary protein restriction of pregnant rats in the F0 generation induces altered methylation of hepatic gene promoters in the adult male offspring in the F1 and F2 generations. Br. J. Nutr. 97, 435-439 (2007).
    • (2007) Br. J. Nutr , vol.97 , pp. 435-439
    • Burdge, G.C.1
  • 127
    • 20344382306 scopus 로고    scopus 로고
    • Metabolic syndrome in childhood: Association with birth weight, maternal obesity, and gestational diabetes mellitus
    • Boney, C. M., Verma, A., Tucker, R. & Vohr, B. R. Metabolic syndrome in childhood: association with birth weight, maternal obesity, and gestational diabetes mellitus. Pediatrics 115, e290-e296 (2005).
    • (2005) Pediatrics , vol.115 , pp. e290-e296
    • Boney, C.M.1    Verma, A.2    Tucker, R.3    Vohr, B.R.4
  • 128
    • 61749094289 scopus 로고    scopus 로고
    • Maternal high-fat diet triggers lipotoxicity in the fetal livers of nonhuman primates
    • McCurdy, C. E. et al. Maternal high-fat diet triggers lipotoxicity in the fetal livers of nonhuman primates. J. Clin. Invest. 119, 323-335 (2009).
    • (2009) J. Clin. Invest , vol.119 , pp. 323-335
    • McCurdy, C.E.1
  • 129
    • 79951670101 scopus 로고    scopus 로고
    • Perinatal exposure to high-fat diet programs energy balance, metabolism and behavior in adulthood
    • Sullivan, E. L., Smith, M. S. & Grove, K. L. Perinatal exposure to high-fat diet programs energy balance, metabolism and behavior in adulthood. Neuroendocrinology 93, 1-8 (2011).
    • (2011) Neuroendocrinology , vol.93 , pp. 1-8
    • Sullivan, E.L.1    Smith, M.S.2    Grove, K.L.3
  • 130
    • 65549163779 scopus 로고    scopus 로고
    • Prenatal stress or high-fat diet increases susceptibility to diet-induced obesity in rat offspring
    • Tamashiro, K. L., Terrillion, C. E., Hyun, J., Koenig, J. I. & Moran, T. H. Prenatal stress or high-fat diet increases susceptibility to diet-induced obesity in rat offspring. Diabetes 58, 1116-1125 (2009 ).
    • (2009) Diabetes , vol.58 , pp. 1116-1125
    • Tamashiro, K.L.1    Terrillion, C.E.2    Hyun, J.3    Koenig, J.I.4    Moran, T.H.5
  • 131
    • 0013530130 scopus 로고    scopus 로고
    • Diet in late pregnancy and glucose-insulin metabolism of the offspring 40 years later
    • Shiell, A. W., Campbell, D. M., Hall, M. H. & Barker, D. J. Diet in late pregnancy and glucose-insulin metabolism of the offspring 40 years later. BJOG 107, 890-895 (2000).
    • (2000) BJOG , vol.107 , pp. 890-895
    • Shiell, A.W.1    Campbell, D.M.2    Hall, M.H.3    Barker, D.J.4
  • 132
    • 84856091906 scopus 로고    scopus 로고
    • From father to offspring: Paternal transmission of depressive-like behaviors
    • Dietz D. M.,Nestler E. J. From father to offspring: paternal transmission of depressive-like behaviors Neuropsychopharmacology 37, 311-312, 2012).
    • (2012) Neuropsychopharmacology , vol.37 , pp. 311-312
    • Dietz, D.M.1    Nestler, E.J.2
  • 133
    • 84893691607 scopus 로고    scopus 로고
    • Parental olfactory experience influences behavior and neural structure in subsequent generations
    • Dias, B. G. & Ressler, K. J. Parental olfactory experience influences behavior and neural structure in subsequent generations. Naure Neurosci. 17, 89-96 (2014).
    • (2014) Naure Neurosci , vol.17 , pp. 89-96
    • Dias, B.G.1    Ressler, K.J.2
  • 134
    • 84877935103 scopus 로고    scopus 로고
    • Paternal stress exposure alters sperm microrna content and reprograms offspring hpa stress axis regulation
    • Rodgers, A. B., Morgan, C. P., Brons on, S. L., Revello, S. & Bale, T. L. Paternal stress exposure alters sperm microRNA content and reprograms offspring HPA stress axis regulation. J. Neurosci. 33, 9003-9012 (2013).
    • (2013) J. Neurosci , vol.33 , pp. 9003-9012
    • Rodgers, A.B.1    Morgan, C.P.2    Bronson, S.L.3    Revello, S.4    Bale, T.L.5
  • 135
    • 77958596171 scopus 로고    scopus 로고
    • Chronic high-fat diet in fathers programs ?-cell dysfunction in female rat offspring
    • Ng, S. F. et al. Chronic high-fat diet in fathers programs ?-cell dysfunction in female rat offspring. Nature 467, 963-966 (2010).
    • (2010) Nature , vol.467 , pp. 963-966
    • Ng, S.F.1
  • 137
    • 78650446334 scopus 로고    scopus 로고
    • Paternally induced transgenerationa l environmental reprogramming of metabolic gene expression in mammals
    • Carone, B. R. et al. Paternally induced transgenerationa l environmental reprogramming of metabolic gene expression in mammals. Cell 143, 1084-1096 (2010).
    • (2010) Cell , vol.143 , pp. 1084-1096
    • Carone, B.R.1
  • 138
    • 20344385787 scopus 로고    scopus 로고
    • Epigenetic transgeneratio nal actions of endocrine disruptors and male fertility
    • Anway, M. D., Cupp, A. S., Uzumcu, M. & Skinner, M. K. Epigenetic transgeneratio nal actions of endocrine disruptors and male fertility. Science 308, 1466-1469 (2005).
    • (2005) Science , vol.308 , pp. 1466-1469
    • Anway, M.D.1    Cupp, A.S.2    Uzumcu, M.3    Skinner, M.K.4
  • 139
    • 32944469027 scopus 로고    scopus 로고
    • Preconceptional fasting of fathers alters serum glucose in offspring of mice
    • Anderson, L. M. et al. Preconceptional fasting of fathers alters serum glucose in offspring of mice. Nutri tion 22, 327-331 (2006).
    • (2006) Nutrition , vol.22 , pp. 327-331
    • Anderson, L.M.1
  • 140
    • 84861514065 scopus 로고    scopus 로고
    • The sperm epigenome and potential implications for the developing embryo
    • Jenkins, T. G. & Carrell, D. T. The sperm epigenome and potential implications for the developing embryo. Reproduction 143, 727-734 (2012).
    • (2012) Reproduction , vol.143 , pp. 727-734
    • Jenkins, T.G.1    Carrell, D.T.2
  • 141
    • 0031897892 scopus 로고    scopus 로고
    • Prenatal exposure to maternal stress and subsequent schizophrenia. The may 1940 invasion of the netherlands
    • van Os, J. & Selten, J. P. Prenatal exposure to maternal stress and subsequent schizophrenia. The May 1940 invasion of The Netherlands. Br. J. Psychiatry 172, 324-326 (1998).
    • (1998) Br. J. Psychiatry , vol.172 , pp. 324-326
    • Van Os, J.1    Selten, J.P.2
  • 142
    • 79953051000 scopus 로고    scopus 로고
    • Depression during pregnancy: Is the developmental impact earlier in boys? A prospective case-control study
    • Ge rardin, P. et al. Depression during pregnancy: is the developmental impact earlier in boys? A prospective case-control study. J. Clin. Psychiatry 72, 378-387 (2010).
    • (2010) J. Clin. Psychiatry , vol.72 , pp. 378-387
    • Gerardin, P.1
  • 143
    • 34249735268 scopus 로고    scopus 로고
    • The epidemiology of autism spectrum disorders
    • Newschaffer, C. J. et al. The epidemiology of autism spectrum disorders. Annu. Rev. Publ. Health 28, 235-258 (2007).
    • (2007) Annu. Rev. Publ. Health , vol.28 , pp. 235-258
    • Newschaffer, C.J.1
  • 144
    • 24044526482 scopus 로고    scopus 로고
    • Timing of prenatal stressors and autism
    • Beversdorf, D. Q. et al. Timing of prenatal stressors and autism. J. Autism Dev. Disord. 35, 471-478 (2005).
    • (2005) J. Autism Dev. Disord , vol.35 , pp. 471-478
    • Beversdorf, D.Q.1
  • 145
    • 84885382216 scopus 로고    scopus 로고
    • Is there a viability-vulnerability tradeoff? Sex differences in fetal programming
    • Sandman, C. A., Glynn, L. M. & Davis, E. P. Is there a viability-vulnerability tradeoff? Sex differences in fetal programming. J. Psychosomat. Res. 75, 327-335 (2013).
    • (2013) J. Psychosomat. Res , vol.75 , pp. 327-335
    • Sandman, C.A.1    Glynn, L.M.2    Davis, E.P.3
  • 146
    • 35148872226 scopus 로고    scopus 로고
    • Maternal immune activation alters fetal brain development through interleukin-6
    • Smith, S. E., Li, J., Garbett, K., Mirnics, K. & Patterson, P. H. Maternal immune activation alters fetal brain development through interleukin-6. J. Neurosci. 27, 10695-10702 (20 07).
    • (2007) J. Neurosci , vol.27 , pp. 10695-10702
    • Smith, S.E.1    Li, J.2    Garbett, K.3    Mirnics, K.4    Patterson, P.H.5
  • 147
    • 84877580425 scopus 로고    scopus 로고
    • Sex differences in microrna regulation of gene expression: No smoke, just mirs
    • Morgan, C. P. & Bale, T. L. Sex differences in microRNA regulation of gene expression: no smoke, just miRs. Biol. Sex Differ. 3, 22 (2012).
    • (2012) Biol. Sex Differ , vol.3 , pp. 22
    • Morgan, C.P.1    Bale, T.L.2
  • 148
  • 149
    • 70350433239 scopus 로고    scopus 로고
    • The epigenetics of sex differences in the brain
    • McCarthy, M. M. et al. The epigenetics of sex differences in the brain. J. Neurosci. 29, 12815-12823 (2009).
    • (2009) J. Neurosci , vol.29 , pp. 12815-12823
    • McCarthy, M.M.1
  • 150
    • 79953732307 scopus 로고    scopus 로고
    • Epigenetic underpinnings of developmental sex difference s in the brain
    • Nugent, B. M. & McCarthy, M. M. Epigenetic underpinnings of developmental sex difference s in the brain. Neuroendocrinology 93, 150-158 (2011).
    • (2011) Neuroendocrinology , vol.93 , pp. 150-158
    • Nugent, B.M.1    McCarthy, M.M.2
  • 151
    • 74949100523 scopus 로고    scopus 로고
    • Epigenetic regulation of estrogen receptor-? Gene expression in the mouse cortex during early postnatal development
    • Westberry, J. M., Trout, A. L. & Wilson, M. E. Epigenetic regulation of estrogen receptor-? gene expression in the mouse cortex during early postnatal development. Endocrinology 151, 731-740 (2010).
    • (2010) Endocrinology , vol.151 , pp. 731-740
    • Westberry, J.M.1    Trout, A.L.2    Wilson, M.E.3
  • 152
    • 77953168537 scopus 로고    scopus 로고
    • Sex differences in epigenetic regulation of the estrogen receptor-? Promoter within the developing preoptic area
    • Kurian, J. R., Olesen, K. M. & Auger, A. P. Sex differences in epigenetic regulation of the estrogen receptor-? promoter within the developing preoptic area. Endocrinology 151, 2297-2305 (2010).
    • (2010) Endocrinology , vol.151 , pp. 2297-2305
    • Kurian, J.R.1    Olesen, K.M.2    Auger, A.P.3
  • 153
    • 69249132599 scopus 로고    scopus 로고
    • Epigenetic control of sexual differentiation of the bed nucleus of the stria terminalis
    • Murray, E. K., Hien, A., de Vries, G. J. & Forger, N. G. Epigenetic control of sexual differentiation of the bed nucleus of the stria terminalis. Endocrinology 150, 4241-4247 (2009).
    • (2009) Endocrinology , vol.150 , pp. 4241-4247
    • Murray, E.K.1    Hien, A.2    De Vries, G.J.3    Forger, N.G.4
  • 154
    • 0028285978 scopus 로고
    • Molecular aspects of sexual differentiation of the rodent brain
    • McCarthy, M. M. Molecular aspects of sexual differentiation of the rodent brain. Psychoneuroendocrinology 19, 415-427 (1994).
    • (1994) Psychoneuroendocrinology , vol.19 , pp. 415-427
    • McCarthy, M.M.1
  • 155
    • 33748109013 scopus 로고    scopus 로고
    • Stress sensitivity and the development of affective disorders
    • Bale, T. L. Stress sensitivity and the development of affective disorders. Horm. Behav. 50, 529-533 (2006).
    • (2006) Horm. Behav , vol.50 , pp. 529-533
    • Bale, T.L.1
  • 156
    • 70349792163 scopus 로고    scopus 로고
    • Neuroendocrine and immune influences on the cns: It's a matter of sex
    • Bale, T. L. Neuroendocrine and immune influences on the CNS: it's a matter of sex. Neuron 64, 13-16 (2009).
    • (2009) Neuron , vol.64 , pp. 13-16
    • Bale, T.L.1
  • 157
    • 84866546211 scopus 로고    scopus 로고
    • Mind-Altering microorganisms: The impact of the gut microbiota on brain and behaviour
    • Cryan, J. F. & Dinan, T. G. Mind-Altering microorganisms: the impact of the gut microbiota on brain and behaviour. Nature Rev. Neurosci. 13, 701-712 (2012).
    • (2012) Nature Rev. Neurosci , vol.13 , pp. 701-712
    • Cryan, J.F.1    Dinan, T.G.2
  • 158
    • 84864757764 scopus 로고    scopus 로고
    • Regulation of the stress response by the gut microbiota: Implications for psychoneuroendocrinology
    • Dinan, T. G. & Cryan, J. F. Regulation of the stress response by the gut microbiota: implications for psychoneuroendocrinology. Psychoneuroendocrinology 37, 1369-1378 (2012).
    • (2012) Psychoneuroendocrinology , vol.37 , pp. 1369-1378
    • Dinan, T.G.1    Cryan, J.F.2
  • 159
    • 84878241830 scopus 로고    scopus 로고
    • The microbiome-gut-brain axis during early life regulates the hippocampal serotonergic system in a sex-dependent manner
    • Clarke, G. et al. The microbiome-gut-brain axis during early life regulates the hippocampal serotonergic system in a sex-dependent manner. Mol. Psychiatry 18, 666-673 (2013).
    • (2013) Mol. Psychiatry , vol.18 , pp. 666-673
    • Clarke, G.1
  • 160
    • 57649239938 scopus 로고    scopus 로고
    • Decoding the epigenetic language of neuronal plasticity
    • Borrelli E.,Nestler E. J.,Allis C. D.,Sassone-Corsi P. Decoding the epigenetic language of neuronal plasticity Neuron 60, 961-974, 2008).
    • (2008) Neuron , vol.60 , pp. 961-974
    • Borrelli, E.1    Nestler, E.J.2    Allis, C.D.3    Sassone-Corsi, P.4
  • 161
    • 27744484673 scopus 로고    scopus 로고
    • Epigenetic mechanisms and gene networks in the nervous system
    • Colvis, C. M. et a l. Epigenetic mechanisms and gene networks in the nervous system. J. Neurosci. 25, 10379-10389 (2005).
    • (2005) J. Neurosci , vol.25 , pp. 10379-10389
    • Colvis, C.M.1
  • 163
    • 84884901586 scopus 로고    scopus 로고
    • Dna methylation regulates associative reward learning
    • Day, J. J. et al. DNA methylation regulates associative reward learning. Nature Neurosci. 16, 1445-1452 (2013).
    • (2013) Nature Neurosci , vol.16 , pp. 1445-1452
    • Day, J.J.1
  • 164
    • 68649088591 scopus 로고    scopus 로고
    • Regulation of chromatin structure in memory formation
    • Roth, T. L. & Sweatt, J. D. Regulation of chromatin structure in memory formation. Curr. Opin. Neurobiol. 19, 336-342 (2009).
    • (2009) Curr. Opin. Neurobiol , vol.19 , pp. 336-342
    • Roth, T.L.1    Sweatt, J.D.2
  • 165
    • 58149308474 scopus 로고    scopus 로고
    • Experience-dependent epi genetic modifications in the central nervous system
    • Sweatt, J. D. Experience-dependent epi genetic modifications in the central nervous system. Biol. Psychiatry 65, 191-197 (2009).
    • (2009) Biol. Psychiatry , vol.65 , pp. 191-197
    • Sweatt, J.D.1
  • 166
    • 84874076991 scopus 로고    scopus 로고
    • Epigenetic regulation of memory formation and maintenance
    • Zovkic, I. B., Guzman-Karlsson, M. C. & Sweatt, J. D. Epigenetic regulation of memory formation and maintenance. Learn. Mem. 20, 61-74 (2013).
    • (2013) Learn. Mem , vol.20 , pp. 61-74
    • Zovkic, I.B.1    Guzman-Karlsson, M.C.2    Sweatt, J.D.3
  • 167
    • 84869094967 scopus 로고    scopus 로고
    • Epigenetic mechanisms in learned fear: Implications for ptsd
    • Zovkic, I. B. & Sweatt, J. D. Epigenetic mechanisms in learned fear: implications for PTSD. Neuropsychopharmacology 38, 77-93 (2013).
    • (2013) Neuropsychopharmacology , vol.38 , pp. 77-93
    • Zovkic, I.B.1    Sweatt, J.D.2
  • 168
    • 84907731374 scopus 로고    scopus 로고
    • A role for histone deacetylases in the cellular and behavioral mechanisms underlying learning and memory
    • Mahgoub, M. & Monteggia, L. M. A role for histone deacetylases in the cellular and behavioral mechanisms underlying learning and memory. Learn. Mem. 21, 564-568 (2014).
    • (2014) Learn. Mem , vol.21 , pp. 564-568
    • Mahgoub, M.1    Monteggia, L.M.2
  • 169
    • 84898850226 scopus 로고    scopus 로고
    • Decoding transcriptional repressor complexes in the adult central nervous system
    • Adachi, M. & Monteggia, L. M. Decoding transcriptional repressor complexes in the adult central nervous system. Neuropharmacology 80, 45-52 (2014).
    • (2014) Neuropharmacology , vol.80 , pp. 45-52
    • Adachi, M.1    Monteggia, L.M.2
  • 170
    • 79957547954 scopus 로고    scopus 로고
    • Behavioral epigenetics
    • Lester, B. M. et al. Behavioral epigenetics. Ann. NY Acad. Sci. 1226, 14-33 (2011).
    • (2011) Ann. NY Acad. Sci , vol.1226 , pp. 14-33
    • Lester, B.M.1
  • 171
  • 172
    • 0001579865 scopus 로고
    • Canalization of development and genetic assimilation of acquired characters
    • Waddington, C. H. Canalization of development and genetic assimilation of acquired characters. Nature 183, 1654-1655 (1959).
    • (1959) Nature , vol.183 , pp. 1654-1655
    • Waddington, C.H.1
  • 174
    • 11144310595 scopus 로고    scopus 로고
    • Intergenerational consequences of fetal programming by in utero exposure to glucocorticoids in rats
    • Drake, A. J., Walker, B. R. & Seckl, J. R. Intergenerational consequences of fetal programming by in utero exposure to glucocorticoids in rats. Am. J. Physiol. Regul. Integr. Comp. Physiol. 288, R34-R38 (2005).
    • (2005) Am. J. Physiol. Regul. Integr. Comp. Physiol , vol.288 , pp. R34-R38
    • Drake, A.J.1    Walker, B.R.2    Seckl, J.R.3
  • 175
    • 0035740678 scopus 로고    scopus 로고
    • Glucocorticoid programming of pituitary-Adrenal function: Mechanisms and physiological consequences
    • O'Regan, D., Welberg, L. L., Holmes, M. C. & Seckl, J. R. Glucocorticoid programming of pituitary-Adrenal function: mechanisms and physiological consequences. Semin. Neonatol. 6, 319-329 (2001).
    • (2001) Semin. Neonatol , vol.6 , pp. 319-329
    • O'Regan, D.1    Welberg, L.L.2    Holmes, M.C.3    Seckl, J.R.4
  • 176
    • 0034837240 scopus 로고    scopus 로고
    • Programming hyperglycaemia in the rat through prenatal exposure to glucocorticoids-fetal effect or maternal influence? J
    • Nyirenda, M. J., Welberg, L. A. & Seckl, J. R. Programming hyperglycaemia in the rat through prenatal exposure to glucocorticoids-fetal effect or maternal influence? J. Endocrinol. 170, 653-660 (2001).
    • (2001) Endocrinol , vol.170 , pp. 653-660
    • Nyirenda, M.J.1    Welberg, L.A.2    Seckl, J.R.3
  • 177
    • 84925226532 scopus 로고    scopus 로고
    • Locus-specific epigenetic remodeling controls addiction-And depression-related behaviors
    • Heller, E. A. et al. Locus-specific epigenetic remodeling controls addiction-And depression-related behaviors. Nature Neurosci. 17, 1720-1727 (2014).
    • (2014) Nature Neurosci , vol.17 , pp. 1720-1727
    • Heller, E.A.1
  • 178
    • 84892464356 scopus 로고    scopus 로고
    • Epigenetic marking of sperm by post-translational modification of histones and protamines
    • Brunner, A. M., Nanni, P. & Mansuy, I. M. Epigenetic marking of sperm by post-translational modification of histones and protamines. Epigenetics Chromatin 7, 2 (2014).
    • (2014) Epigenetics Chromatin , vol.7 , pp. 2
    • Brunner, A.M.1    Nanni, P.2    Mansuy, I.M.3
  • 179
    • 84911412050 scopus 로고    scopus 로고
    • Lifetime stress experience: Transgenerational epigenetics and germ cell programming
    • Bale, T. L. Lifetime stress experience: transgenerational epigenetics and germ cell programming. Dialogues Clin. Neurosci. 16, 297-305 (2014).
    • (2014) Dialogues Clin. Neurosci , vol.16 , pp. 297-305
    • Bale, T.L.1
  • 180
    • 33845784376 scopus 로고    scopus 로고
    • The chromatid body: A germ-cell-specific rna-processing centre
    • Kotaja, N. & Sassone-Corsi, P. The chromatid body: a germ-cell-specific RNA-processing centre. Nature Rev. Mol. Cell Biol. 8, 85-90 (2007).
    • (2007) Nature Rev. Mol. Cell Biol , vol.8 , pp. 85-90
    • Kotaja, N.1    Sassone-Corsi, P.2


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