Targeted placental deletion of OGT recapitulates the prenatal stress phenotype including hypothalamic mitochondrial dysfunction

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 26, 2014, Pages 9639-9644

  Howerton, Christopher L ^a   Bale, Tracy L ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

17b HSD3; Hypothalamus; Mitochondria; Neurodevelopment

Indexed keywords

17 BETA HYDROXYSTEROID DEHYDROGENASE 3; ANDROSTENEDIONE; CYTOCHROME C OXIDASE; DNA DIRECTED RNA POLYMERASE; O LINKED N ACETYLGLUCOSAMINE TRANSFERASE; RNA POLYMERASE II; TESTOSTERONE; TESTOSTERONE 17BETA DEHYDROGENASE; TRANSFERASE; UNCLASSIFIED DRUG;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANOGENITAL DISTANCE; ARTICLE; BODY WEIGHT; BRAIN; CHROMATIN STRUCTURE; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENZYME ACTIVITY; ENZYME ASSAY; FEMALE; GENE DELETION; GENE EXPRESSION; GENE FUNCTION; GENE LOCUS; GENETIC TRANSCRIPTION; GENOTYPE; HISTONE MODIFICATION; HYPOTHALAMIC MITOCHONDRIAL DYSFUNCTION; HYPOTHALAMUS DISEASE; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; IMMOBILIZATION STRESS; MALE; MATERNAL STRESS; MICROARRAY ANALYSIS; MITOSIS; MOUSE; NONHUMAN; PHENOTYPE; PLACENTA; PLACENTA DEVELOPMENT; PRENATAL STRESS; PRIORITY JOURNAL; PROGENY; PROTEIN FOLDING; RESPIRATORY CHAIN; SEX DIFFERENTIATION; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION SITE;

17B-HSD3; HYPOTHALAMUS; MITOCHONDRIA; NEURODEVELOPMENT;

ANALYSIS OF VARIANCE; ANIMALS; BIOLOGICAL MARKERS; CHROMATIN IMMUNOPRECIPITATION; FEMALE; FETAL DISEASES; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; HYPOTHALAMUS; MALE; MICE; MICE, INBRED C57BL; MICROARRAY ANALYSIS; MITOCHONDRIAL DISEASES; N-ACETYLGLUCOSAMINYLTRANSFERASES; PITUITARY-ADRENAL SYSTEM; PLACENTA; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; REAL-TIME POLYMERASE CHAIN REACTION; STRESS, PHYSIOLOGICAL;

EID: 84903721712     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1401203111     Document Type: Article

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