EC300: a phage-based, bacteriolysin-like protein with enhanced antibacterial activity against Enterococcus faecalis

Applied Microbiology and Biotechnology

Volumn 99, Issue 12, 2015, Pages 5137-5149

  Proença, Daniela ^a   Leandro, Clara ^a   Garcia, Miguel ^a   Pimentel, Madalena ^b   São José, Carlos ^b  

^a Technophage SA   (Portugal)

^b RESEARCH INSTITUTE FOR MEDICINES IMED ULISBOA   (Portugal)

Author keywords

Chimerical enzyme; Endolysin; Enterococcus faecalis; Peptidoglycan hydrolase; Virion associated lysin

Indexed keywords

ANTIBIOTICS; BACILLI; ENZYMES; PROTEINS;

ANTI-BACTERIAL ACTIVITY; ANTI-BACTERIAL AGENTS; CELL WALL-BINDING DOMAIN; ENDOLYSIN; ENTEROCOCCUS FAECALIS; GRAM-POSITIVE PATHOGENS; PEPTIDOGLYCAN HYDROLASE; VIRION-ASSOCIATED LYSIN;

BACTERIA;

ANTIBIOTIC AGENT; EC 300; HYDROLASE; UNCLASSIFIED DRUG; ANTIINFECTIVE AGENT; LYSIN; MUCOPROTEIN; VIRUS PROTEIN;

ANTIBIOTIC RESISTANCE; ANTIMICROBIAL ACTIVITY; BACTERIOPHAGE; ENZYME ACTIVITY; GROWTH RATE; PROTEIN;

ANTIBACTERIAL ACTIVITY; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL GROWTH; BACTERIOLYSIS; BACTERIOPHAGE; DNA PURIFICATION; ENTEROCOCCUS FAECALIS; ESCHERICHIA COLI; EXPRESSION VECTOR; GEL PERMEATION CHROMATOGRAPHY; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; RECOMBINANT PLASMID; SITE DIRECTED MUTAGENESIS; VIRION; CHEMISTRY; DRUG EFFECTS; ENZYMOLOGY; GENETICS; GRAM POSITIVE INFECTION; GROWTH, DEVELOPMENT AND AGING; HUMAN; ISOLATION AND PURIFICATION; METABOLISM; MICROBIOLOGY; PROTEIN ENGINEERING;

BACTERIA (MICROORGANISMS); ENTEROCOCCUS FAECALIS; POSIBACTERIA;

ANTI-BACTERIAL AGENTS; BACTERIOPHAGES; ENTEROCOCCUS FAECALIS; GRAM-POSITIVE BACTERIAL INFECTIONS; HUMANS; MUCOPROTEINS; PROTEIN ENGINEERING; VIRAL PROTEINS;

EID: 84929948662     PISSN: 01757598     EISSN: 14320614     Source Type: Journal    
DOI: 10.1007/s00253-015-6483-7     Document Type: Article

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