Characterization of tumour necrosis factor-alpha genetic variants and mRNA expression in patients with severe sepsis

International Journal of Immunogenetics

Volumn 35, Issue 4-5, 2008, Pages 279-285

  O'Dwyer, M J ^a,b   Mankan, A K ^a   Ryan, A W ^a   Lawless, M W ^a   Stordeur, P ^c   Kelleher, D ^a   McManus, R ^a   Ryan, T ^b  

^a TRINITY COLLEGE DUBLIN   (Ireland)

^b ST JAMES S HOSPITAL   (Ireland)

^c ERASME HOSPITAL   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; GENOMIC DNA; MESSENGER RNA; TUMOR NECROSIS FACTOR ALPHA;

ABDOMINAL INFECTION; ADULT; AGED; ALLELE; ARTICLE; BLOOD SAMPLING; CAUCASIAN; CYTOKINE PRODUCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GENETIC POLYMORPHISM; HAPLOTYPE; HUMAN; INTENSIVE CARE UNIT; MAJOR CLINICAL STUDY; MALE; PATHOGENESIS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BLOOD LEVEL; RESPIRATORY TRACT INFECTION; RISK ASSESSMENT; SEPSIS; SINGLE NUCLEOTIDE POLYMORPHISM; SURVIVAL RATE;

ADULT; AGED; AGED, 80 AND OVER; ALLELES; FEMALE; GENE EXPRESSION REGULATION; GENE FREQUENCY; GENETIC VARIATION; HAPLOTYPES; HUMANS; MALE; MIDDLE AGED; RNA, MESSENGER; SEPSIS; TUMOR NECROSIS FACTOR-ALPHA; YOUNG ADULT;

ANIMALIA;

EID: 52649170772     PISSN: 17443121     EISSN: 1744313X     Source Type: Journal    
DOI: 10.1111/j.1744-313X.2008.00773.x     Document Type: Article

References (26)

1. Abraham, E., Glauser, M.P., Butler, T., Garbino, J., Gelmont, D., Laterre, P.F. et al 1997) p55 Tumor necrosis factor receptor fusion protein in the treatment of patients with severe sepsis and septic shock. A randomized controlled multicenter trial. Ro 45-2081 Study Group. JAMA, 277, 1531.
2. Anonymous 1992) American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference: definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Critical Care Medicine, 20, 864.
3. Appoloni, O., Dupont, E., Vandercruys, M., Andriens, M., Duchateau, J. Vincent, J.L. (2001) Association of tumor necrosis factor-2 allele with plasma tumor necrosis factor-alpha levels and mortality from septic shock. American Journal of Medicine, 110, 486.
4. Bjerre, A., Brusletto, B., Hoiby, E.A., Kierulf, P. Brandtzaeg, P. (2004) Plasma interferon-gamma and interleukin-10 concentrations in systemic meningococcal disease compared with severe systemic Gram-positive septic shock. Critical Care Medicine, 32, 433.
5. Clark, M.F. Baudouin, S.V. (2006) A systematic review of the quality of genetic association studies in human sepsis. Intensive Care Medicine, 32, 1706.
6. Damas, P., Canivet, J.L., de Groote, D., Vrindts, Y., Albert, A., Franchimont, P. Lamy, M. (1997) Sepsis and serum cytokine concentrations. Critical Care Medicine, 25, 405.
7. Dharmana, E., Keuter, M., Netea, M.G., Verschueren, I.C. Kullberg, B.J. (2002) Divergent effects of tumor necrosis factor-alpha and lymphotoxin-alpha on lethal endotoxemia and infection with live Salmonella typhimurium in mice. European Cytokine Network, 13, 104.
8. Fisher, C.J. Jr, Agosti, J.M., Opal, S.M., Lowry, S.F., Balk, R.A., Sadoff, J.C., Abraham, E., Schein, R.M. Benjamin, E. (1996) Treatment of septic shock with the tumor necrosis factor receptor: Fc fusion protein. The Soluble TNF Receptor Sepsis Study Group. New England Journal of Medicine, 334, 1697.
9. Fu, N., Drinnenberg, I., Kelso, J., Wu, J.R., Paabo, S., Zeng, R. Khaitovich, P. (2007) Comparison of protein and mRNA expression evolution in humans and chimpanzees. PLoS ONE, 2, e216.
10. Goldie, A.S., Fearon, K.C., Ross, J.A., Barclay, G.R., Jackson, R.E., Grant, I.S., Ramsay, G., Blyth, A.S. Howie, J.C. (1995) Natural cytokine antagonists and endogenous antiendotoxin core antibodies in sepsis syndrome. The Sepsis Intervention Group. JAMA, 274, 172.
11. Judson, R., Stephens, J.C. Windemuth, A. (2000) The predictive power of haplotypes in clinical response. Pharmacogenomics, 1, 15.
12. Kovar, F.M., Marsik, C., Cvitko, T., Wagner, O.F., Jilma, B. Endler, G. (2007) The tumor necrosis factor alpha -308 G/A polymorphism does not influence inflammation and coagulation response in human endotoxemia. Shock, 27, 238.
13. Mira, J.P., Cariou, A., Grall, F., Delclaux, C., Losser, M.R., Heshmati, F. et al 1999) Association of TNF2, a TNF-alpha promoter polymorphism, with septic shock susceptibility and mortality: a multicenter study. JAMA, 282, 561.
14. O'Dwyer, M., J.Mankan, A.K., Stordeur, P., O'Connell, B., Duggan, E., White, M., Kelleher, D.P., McManus, R. Ryan, T. (2006) The occurrence of severe sepsis and septic shock are related to distinct patterns of cytokine gene expression. Shock, 26, 544.
15. Ono, S., Ueno, C., Aosasa, S., Tsujimoto, H., Seki, S. Mochizuki, H. (2001) Severe sepsis induces deficient interferon-gamma and interleukin-12 production, but interleukin-12 therapy improves survival in peritonitis. American Journal of Surgery, 182, 491.
16. Rahman, P., Siannis, F., Butt, C., Farewell, V., Peddle, L., Pellett, F. Gladman, D. (2006) TNFalpha polymorphisms and risk of psoriatic arthritis. Annals of the Rheumatic Diseases, 65, 919.
17. Schippers, E.F., van't Veer, C., van Voorden, S., Martina, C.A., le Cessie, S. van Dissel, J.T. (2004) TNF-alpha promoter, Nod2 and toll-like receptor-4 polymorphisms and the in vivo and ex vivo response to endotoxin. Cytokine, 26, 16.
18. Schmitt-Grohe, S., Stuber, F., Book, M., Bargon, J., Wagner, T.O., Naujoks, C., Schubert, R., Lentze, M.J. Zielen, S. (2006) TNF-alpha promoter polymorphism in relation to TNF-alpha production and clinical status in cystic fibrosis. Lung, 184, 99.
19. Sorensen, T.I., Nielsen, G.G., Andersen, P.K. Teasdale, T.W. (1988) Genetic and environmental influences on premature death in adult adoptees. New England Journal of Medicine, 318, 727.
20. Stordeur, P., Poulin, L.F., Craciun, L., Zhou, L., Schandene, L., de Lavareille, A., Goriely, S. Goldman, M. (2002) Cytokine mRNA quantification by real-time PCR. Journal of Immunological Methods, 259, 55.
21. Stuber, F., Udalova, I.A., Book, M., Drutskaya, L.N., Kuprash, D.V., Turetskaya, R.L., Schade, F.U. Nedospasov, S.A. (1995) -308 tumor necrosis factor (TNF) polymorphism is not associated with survival in severe sepsis and is unrelated to lipopolysaccharide inducibility of the human TNF promoter. Journal of Inflammation, 46, 42.
22. Tang, G.J., Huang, S.L., Yien, H.W., Chen, W.S., Chi, C.W., Wu, C.W., Lui, W.Y., Chiu, J.H. Lee, T.Y. (2000) Tumor necrosis factor gene polymorphism and septic shock in surgical infection. Critical Care Medicine, 28, 2733.
23. Teti, G., Mancuso, G. Tomasello, F. (1993) Cytokine appearance and effects of anti-tumor necrosis factor alpha antibodies in a neonatal rat model of group B streptococcal infection. Infection and Immunity, 61, 227.
24. Tracey, K.J., Beutler, B., Lowry, S.F., Merryweather, J., Wolpe, S., Milsark, I.W. et al 1986) Shock and tissue injury induced by recombinant human cachectin. Science, 234, 470.
25. Wayte, J., Silva, A.T., Krausz, T. Cohen, J. (1993) Observations on the role of tumor necrosis factor-alpha in a murine model of shock due to Streptococcus pyogenes. Critical Care Medicine, 21, 1207.
26. Whitley, E. Ball, J. (2002) Statistics review 4: sample size calculations. Critical Care Medicine, 6, 335.