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Volumn 55, Issue 13, 2015, Pages 1918-1928

Assessing Herbal Products with Health Claims

Author keywords

20 hydroxyecdysone; ecdysteroids; health claims legislation; Herbal products; hormone nuclear receptors; QSAR

Indexed keywords

BINS; COMPUTATIONAL CHEMISTRY; LAWS AND LEGISLATION; PLANT EXTRACTS; TRANSCRIPTION FACTORS;

EID: 84929861316     PISSN: 10408398     EISSN: 15497852     Source Type: Journal    
DOI: 10.1080/10408398.2012.726661     Document Type: Article
Times cited : (13)

References (55)
  • 1
    • 79958763372 scopus 로고    scopus 로고
    • Liver X receptors as regulators of macrophage inflammatory and metabolic pathways
    • N.A-González, and A.Castrillo, (2011). Liver X receptors as regulators of macrophage inflammatory and metabolic pathways. Biochim. Biophys. Acta (BBA) - Mol. Basis Dis. 1812(8):982–994.
    • (2011) Biochim. Biophys. Acta (BBA) - Mol. Basis Dis. , vol.1812 , Issue.8 , pp. 982-994
    • A-González, N.1    Castrillo, A.2
  • 2
    • 50949106108 scopus 로고    scopus 로고
    • Ecdysteroids in spinach (Spinacia oleracea L.): Biosynthesis, transport and regulation of levels
    • A.Bakrim,, A.Maria,, F.Sayah,, R.Lafont, and N.Takvorian, (2008). Ecdysteroids in spinach (Spinacia oleracea L.): Biosynthesis, transport and regulation of levels. Plant Physiol. Biochem. 46(10):844–54.
    • (2008) Plant Physiol. Biochem. , vol.46 , Issue.10 , pp. 844-854
    • Bakrim, A.1    Maria, A.2    Sayah, F.3    Lafont, R.4    Takvorian, N.5
  • 3
    • 39049112601 scopus 로고    scopus 로고
    • Phytoecdysteroids and anabolic-androgenic steroids–structure and effects on humans
    • M.Bathori,, N.Toth,, A.Hunyadi,, A.Marki, and E.Zador, (2008). Phytoecdysteroids and anabolic-androgenic steroids–structure and effects on humans. Curr. Med. Chem. 15(1):75–91.
    • (2008) Curr. Med. Chem. , vol.15 , Issue.1 , pp. 75-91
    • Bathori, M.1    Toth, N.2    Hunyadi, A.3    Marki, A.4    Zador, E.5
  • 6
    • 31344462108 scopus 로고    scopus 로고
    • Effect of ecdysterone on glucose metabolism in vitro
    • Q.Chen,, Y.Xia, and Z.Qiu, (2006). Effect of ecdysterone on glucose metabolism in vitro. Life Sci. 78 (10):1108–1113.
    • (2006) Life Sci. , vol.78 , Issue.10 , pp. 1108-1113
    • Chen, Q.1    Xia, Y.2    Qiu, Z.3
  • 7
  • 8
    • 84857362332 scopus 로고    scopus 로고
    • Maps and legends: The quest for dissociated ligands of the glucocorticoid receptor
    • A.R.Clark, and M.G.Belvisi, (2012). Maps and legends: The quest for dissociated ligands of the glucocorticoid receptor. Pharmacol. Ther. 134(1):54–67.
    • (2012) Pharmacol. Ther. , vol.134 , Issue.1 , pp. 54-67
    • Clark, A.R.1    Belvisi, M.G.2
  • 9
    • 0142088809 scopus 로고    scopus 로고
    • Quantitative structure-activity relationships for human health effects: Commonalities with other endpoints
    • M.T.Cronin,, J.C.Dearden,, J.D.Walker, and A.P.Worth, (2003). Quantitative structure-activity relationships for human health effects: Commonalities with other endpoints. Environ. Toxicol. Chem. 22(8):1829–1843.
    • (2003) Environ. Toxicol. Chem. , vol.22 , Issue.8 , pp. 1829-1843
    • Cronin, M.T.1    Dearden, J.C.2    Walker, J.D.3    Worth, A.P.4
  • 10
    • 61849180390 scopus 로고    scopus 로고
    • Detection and identification of 20-hydroxyecdysone metabolites in calf urine by liquid chromatography-high resolution or tandem mass spectrometry measurements and establishment of their kinetics of elimination after 20-hydroxyecdysone administration
    • B.Destrez,, G.Pinel,, F.Monteau,, R.Lafont, and B.Le Bizec, (2009). Detection and identification of 20-hydroxyecdysone metabolites in calf urine by liquid chromatography-high resolution or tandem mass spectrometry measurements and establishment of their kinetics of elimination after 20-hydroxyecdysone administration. Anal. Chim. Acta 637(1–2):178–184.
    • (2009) Anal. Chim. Acta , vol.637 , Issue.1-2 , pp. 178-184
    • Destrez, B.1    Pinel, G.2    Monteau, F.3    Lafont, R.4    Le Bizec, B.5
  • 11
    • 0000017924 scopus 로고
    • A strategy for the identification of ecdysteroid receptor agonists and antagonists from plants
    • L.Dinan, (1995). A strategy for the identification of ecdysteroid receptor agonists and antagonists from plants. Eur. J. Entomol. 92:271–283.
    • (1995) Eur. J. Entomol. , vol.92 , pp. 271-283
    • Dinan, L.1
  • 12
    • 0035371607 scopus 로고    scopus 로고
    • Phytoecdysteroids: Biological aspects
    • L.Dinan, (2001). Phytoecdysteroids: Biological aspects. Phytochemistry 57:325–339.
    • (2001) Phytochemistry , vol.57 , pp. 325-339
    • Dinan, L.1
  • 13
    • 70350743206 scopus 로고    scopus 로고
    • The karlson lecture. Phytoecdysteroids: What use are they?
    • L.Dinan, (2009). The karlson lecture. Phytoecdysteroids: What use are they? Arch. Insect. Biochem. Physiol. 72(3):126–141.
    • (2009) Arch. Insect. Biochem. Physiol. , vol.72 , Issue.3 , pp. 126-141
    • Dinan, L.1
  • 14
    • 33751054112 scopus 로고    scopus 로고
    • Effects and applications of arthropod steroid hormones (ecdysteroids) in mammals
    • L.Dinan, and R.Lafont, (2006). Effects and applications of arthropod steroid hormones (ecdysteroids) in mammals. J. Endocrinol. 191:1–8.
    • (2006) J. Endocrinol. , vol.191 , pp. 1-8
    • Dinan, L.1    Lafont, R.2
  • 15
    • 84929885449 scopus 로고    scopus 로고
    • Regulation (EC) No 258/97 of the European parliament and of the council of 27 January 1997 concerning novel foods and novel food ingredients
    • L 43/1
    • E.EC, E. (1997). Regulation (EC) No 258/97 of the European parliament and of the council of 27 January 1997 concerning novel foods and novel food ingredients. Off. J. Eur. Union L 43/1.
    • (1997) Off. J. Eur. Union
    • Ec, E.1
  • 16
    • 0012111484 scopus 로고    scopus 로고
    • Directive 2001/83/EC of the European parliament and of the council of 6 November 2001 on the community code relating to medicinal products for human use
    • L 311/67
    • E.EC, E. (2001). Directive 2001/83/EC of the European parliament and of the council of 6 November 2001 on the community code relating to medicinal products for human use. Off. J. Eur. Commun. L 311/67.
    • (2001) Off. J. Eur. Commun.
    • Ec, E.1
  • 17
    • 0141859150 scopus 로고    scopus 로고
    • Directive 2002/46/EC of the European parliament and of the council of 10 June 2002 on the approximation of the laws of the member states relating to food supplements
    • L 183/51
    • E.EC, E. (2002a). Directive 2002/46/EC of the European parliament and of the council of 10 June 2002 on the approximation of the laws of the member states relating to food supplements. Off. J. Eur. Commun. L 183/51.
    • (2002) Off. J. Eur. Commun.
    • Ec, E.1
  • 18
    • 0141635634 scopus 로고    scopus 로고
    • Regulation (EC) No 178/2002 of the European parliament and of the council of 28 January 2002 laying down the general principles and requirements of food law, establishing the European food safety authority and laying down procedures in matters of food safety
    • L 31/1
    • E.EC, E. (2002b). Regulation (EC) No 178/2002 of the European parliament and of the council of 28 January 2002 laying down the general principles and requirements of food law, establishing the European food safety authority and laying down procedures in matters of food safety. Off. J. Eur. Commun. L 31/1.
    • (2002) Off. J. Eur. Commun.
    • Ec, E.1
  • 19
    • 33845621724 scopus 로고    scopus 로고
    • Directive 2004/24/EC of the European parliament and of the council of 31 March 2004 amending, as regards traditional herbal medicinal products, Directive 2001/83/EC on the community code relating to medicinal products for human use
    • L 136/85
    • E.EC, E. (2004a). Directive 2004/24/EC of the European parliament and of the council of 31 March 2004 amending, as regards traditional herbal medicinal products, Directive 2001/83/EC on the community code relating to medicinal products for human use. Off. J. Eur. Unio. L 136/85.
    • (2004) Off. J. Eur. Unio.
    • Ec, E.1
  • 20
    • 84929906402 scopus 로고    scopus 로고
    • Regulation (EC) No 882/2004 of the European parliament and of the council on official controls performed to ensure the verification of compliance with feed and food law, animal health and animal welfare rules
    • L 165/1
    • E.EC, E. (2004b). Regulation (EC) No 882/2004 of the European parliament and of the council on official controls performed to ensure the verification of compliance with feed and food law, animal health and animal welfare rules. Off. J. Eur. Unio. L 165/1.
    • (2004) Off. J. Eur. Unio.
    • Ec, E.1
  • 21
    • 34548281820 scopus 로고    scopus 로고
    • Commission directive 2006/37/EC of 30 march 2006 amending annex II to Directive 2002/46/EC of the European parliament and of the council as regards the inclusion of certain substances
    • L 94/32
    • E.EC, E. (2006a). Commission directive 2006/37/EC of 30 march 2006 amending annex II to Directive 2002/46/EC of the European parliament and of the council as regards the inclusion of certain substances. Off. J. Eur. Unio. L 94/32.
    • (2006) Off. J. Eur. Unio.
    • Ec, E.1
  • 22
    • 34147219282 scopus 로고    scopus 로고
    • Regulation (EC) No 1924/2006 of the European parliament and of the council of 20 December 2006 on nutrition and health claims made on foods
    • L 404/9
    • E.EC, E. (2006b). Regulation (EC) No 1924/2006 of the European parliament and of the council of 20 December 2006 on nutrition and health claims made on foods. Off. J. Eur. Unio. L 404/9.
    • (2006) Off. J. Eur. Unio.
    • Ec, E.1
  • 23
    • 84868593035 scopus 로고    scopus 로고
    • Commission regulation (EC) No 1170/2009 of 30 November 2009 amending Directive 2002/46/EC of the European parliament and of council and regulation (EC) No 1925/2006 of the European parliament and of the council as regards the lists of vitamin and minerals and their forms that can be added to foods, including food supplements
    • L 314/36
    • E.EC, E. (2009a). Commission regulation (EC) No 1170/2009 of 30 November 2009 amending Directive 2002/46/EC of the European parliament and of council and regulation (EC) No 1925/2006 of the European parliament and of the council as regards the lists of vitamin and minerals and their forms that can be added to foods, including food supplements. Off. J. Eur. Unio. L 314/36.
    • (2009) Off. J. Eur. Unio.
    • Ec, E.1
  • 24
    • 84929903662 scopus 로고    scopus 로고
    • Directive 2009/39/EC of the European parliament and of the council of 6 May 2009 on foodstuffs intended for particular nutritional uses
    • L 124/21
    • E.EC, E. (2009b). Directive 2009/39/EC of the European parliament and of the council of 6 May 2009 on foodstuffs intended for particular nutritional uses. Off. J. Eur. Union L 124/21.
    • (2009) Off. J. Eur. Union
    • Ec, E.1
  • 25
    • 84929853617 scopus 로고    scopus 로고
    • Commission regulation (EU) No 1161/2011 of 14 November 2011 amending Directive 2002/46/EC of the European parliament and of the council, regulation (EC) No 1925/2006 of the European parliament and of the council and commission regulation (EC) No 953/2009 as regards the lists of mineral substances that can be added to foods
    • L 296/29
    • E.EC, E. (2011). Commission regulation (EU) No 1161/2011 of 14 November 2011 amending Directive 2002/46/EC of the European parliament and of the council, regulation (EC) No 1925/2006 of the European parliament and of the council and commission regulation (EC) No 953/2009 as regards the lists of mineral substances that can be added to foods. Off. J. Eur. Unio. L 296/29.
    • (2011) Off. J. Eur. Unio.
    • Ec, E.1
  • 26
    • 84929928694 scopus 로고    scopus 로고
    • Available from
    • FDA (2012). 2012 [cited 2012 2012]. Available from http://www.fda.gov/Food/GuidanceComplianceRegulatoryInformation/GuidanceDocuments/DietarySupplements/ucm257563.htm.
    • (2012) 2012 [cited 2012 2012]
  • 29
    • 77954261218 scopus 로고    scopus 로고
    • Ecdysteroids elicit a rapid Ca2+ flux leading to Akt activation and increased protein synthesis in skeletal muscle cells
    • J.Gorelick-Feldman,, W.Cohick, and I.Raskin, (2010). Ecdysteroids elicit a rapid Ca2+ flux leading to Akt activation and increased protein synthesis in skeletal muscle cells. Steroids 75(10):632–637.
    • (2010) Steroids , vol.75 , Issue.10 , pp. 632-637
    • Gorelick-Feldman, J.1    Cohick, W.2    Raskin, I.3
  • 31
    • 33644644296 scopus 로고    scopus 로고
    • Legislation relating to nutraceuticals in the European union with a particular focus on botanical-sourced products
    • O.P.Gulati, and P.Berry Ottaway, (2006). Legislation relating to nutraceuticals in the European union with a particular focus on botanical-sourced products. Toxicology 221(1):75–87.
    • (2006) Toxicology , vol.221 , Issue.1 , pp. 75-87
    • Gulati, O.P.1    Berry Ottaway, P.2
  • 32
    • 84871700394 scopus 로고    scopus 로고
    • New drugs from ancient texts
    • G.Humphreys, (2012). New drugs from ancient texts. Bull. World Health Organ. 90:562–563.
    • (2012) Bull. World Health Organ. , vol.90 , pp. 562-563
    • Humphreys, G.1
  • 35
    • 78649325141 scopus 로고    scopus 로고
    • Ecdysteroids from Chenopodium quinoa Willd., an ancient Andean crop of high nutritional value
    • S.Kumpun,, A.Maria,, S.Crouzet,, N.Evrard-Todeschi,, J.-P.Girault, and R.Lafont, (2011b). Ecdysteroids from Chenopodium quinoa Willd., an ancient Andean crop of high nutritional value. Food Chem. 125(4):1226–1234.
    • (2011) Food Chem. , vol.125 , Issue.4 , pp. 1226-1234
    • Kumpun, S.1    Maria, A.2    Crouzet, S.3    Evrard-Todeschi, N.4    Girault, J.-P.5    Lafont, R.6
  • 36
    • 0035746532 scopus 로고    scopus 로고
    • Hypoglycemic activity of the total ecdysteroid extract from Ajuga turkestanica
    • T.A.Kutepova,, V.N.Syrov,, Z.A.Khushbaktova, and Z.Saatov, (2001). Hypoglycemic activity of the total ecdysteroid extract from Ajuga turkestanica. Pharm. Chem. J. 35(11):608–609.
    • (2001) Pharm. Chem. J. , vol.35 , Issue.11 , pp. 608-609
    • Kutepova, T.A.1    Syrov, V.N.2    Khushbaktova, Z.A.3    Saatov, Z.4
  • 37
    • 2442649769 scopus 로고    scopus 로고
    • Practical uses for ecdysteroids in mammals including humans: An update
    • R.Lafont, and L.Dinan, (2003). Practical uses for ecdysteroids in mammals including humans: An update. J. Insect Sci. 3:7.
    • (2003) J. Insect Sci. , vol.3 , pp. 7
    • Lafont, R.1    Dinan, L.2
  • 40
    • 58549110256 scopus 로고    scopus 로고
    • Semi-synthetic ecdysteroids as gene-switch actuators: Synthesis, structure-activity relationships, and prospective ADME properties
    • S.Lapenna,, L.Dinan,, J.Friz,, A.Hopfinger,, J.Liu, and R.E.Hormann, (2009). Semi-synthetic ecdysteroids as gene-switch actuators: Synthesis, structure-activity relationships, and prospective ADME properties. Chem. Med. Chem. 4:55–68.
    • (2009) Chem. Med. Chem. , vol.4 , pp. 55-68
    • Lapenna, S.1    Dinan, L.2    Friz, J.3    Hopfinger, A.4    Liu, J.5    Hormann, R.E.6
  • 41
    • 55949092016 scopus 로고    scopus 로고
    • Ecdysteroid ligand-receptor selectivity: Exploring trends to design orthogonal gene switches
    • S.Lapenna,, J.Friz,, A.Barlow,, R.Palli,, L.Dinan, and R.E.Hormann, (2008). Ecdysteroid ligand-receptor selectivity: Exploring trends to design orthogonal gene switches. FEBS J. 275:5785–5809.
    • (2008) FEBS J. , vol.275 , pp. 5785-5809
    • Lapenna, S.1    Friz, J.2    Barlow, A.3    Palli, R.4    Dinan, L.5    Hormann, R.E.6
  • 43
    • 77955982215 scopus 로고    scopus 로고
    • β-Ecdysone has bone protective but no estrogenic effects in ovariectomized rats
    • D.Seidlova-Wuttke,, D.Christel,, P.Kapur,, B.T.Nguyen,, H.Jarry, and W.Wuttke, (2010). β-Ecdysone has bone protective but no estrogenic effects in ovariectomized rats. Phytomedicine 17(11):884–889.
    • (2010) Phytomedicine , vol.17 , Issue.11 , pp. 884-889
    • Seidlova-Wuttke, D.1    Christel, D.2    Kapur, P.3    Nguyen, B.T.4    Jarry, H.5    Wuttke, W.6
  • 44
    • 82455206245 scopus 로고    scopus 로고
    • Regulations applicable to plant food supplements and related products in the European union
    • V.Silano,, P.Coppens,, A.Larranaga-Guetaria,, P.Minghetti, and R.Roth-Ehrang, (2011). Regulations applicable to plant food supplements and related products in the European union. Food Funct. 2(12):710–719.
    • (2011) Food Funct. , vol.2 , Issue.12 , pp. 710-719
    • Silano, V.1    Coppens, P.2    Larranaga-Guetaria, A.3    Minghetti, P.4    Roth-Ehrang, R.5
  • 45
    • 0002545589 scopus 로고
    • Ecdysteroids in vertebrates: Pharmacological aspects
    • Koolman J., (ed), Taylor & Francis, Stuttgart:
    • P.Simon, and J.Koolman, (1989). Ecdysteroids in vertebrates: Pharmacological aspects. In: Ecdysone: From Chemistry to Mode of Action. pp. 254–259. J.Koolman,, Ed., Taylor & Francis, Stuttgart.
    • (1989) Ecdysone: From Chemistry to Mode of Action , pp. 254-259
    • Simon, P.1    Koolman, J.2
  • 46
    • 0000974755 scopus 로고
    • Insect hormones - ecdysteroids: Their presence and actions in vertebrates
    • K.Sláma, and R.Lafont, (1995). Insect hormones - ecdysteroids: Their presence and actions in vertebrates. The Eur. J. Entomol. 92:355–377.
    • (1995) The Eur. J. Entomol. , vol.92 , pp. 355-377
    • Sláma, K.1    Lafont, R.2
  • 47
    • 0034521024 scopus 로고    scopus 로고
    • Comparative experimental investigation of the anabolic activity of phytoecdysteroids and steranabols
    • V.Syrov, (2000). Comparative experimental investigation of the anabolic activity of phytoecdysteroids and steranabols. Pharm. Chem. J. 34(4):193–197.
    • (2000) Pharm. Chem. J. , vol.34 , Issue.4 , pp. 193-197
    • Syrov, V.1
  • 48
    • 77953516303 scopus 로고    scopus 로고
    • Phytoecdysteroids and vitamin D analogues - similarities in structure and mode of action
    • N.Toth,, A.Hunyadi,, M.Bathori, and E.Zador, (2010). Phytoecdysteroids and vitamin D analogues - similarities in structure and mode of action. Curr. Med. Chem. 17(18):1974–1994.
    • (2010) Curr. Med. Chem. , vol.17 , Issue.18 , pp. 1974-1994
    • Toth, N.1    Hunyadi, A.2    Bathori, M.3    Zador, E.4
  • 49
    • 34250795654 scopus 로고    scopus 로고
    • Prediction of rodent carcinogenic potential of naturally occurring chemicals in the human diet using high-throughput QSAR predictive modeling
    • L.G.Valerio,, Jr., K.B.Arvidson,, R.F.Chanderbhan, and J.F.Contrera, (2007). Prediction of rodent carcinogenic potential of naturally occurring chemicals in the human diet using high-throughput QSAR predictive modeling. Toxicol. Appl. Pharm. 222(1):1–16.
    • (2007) Toxicol. Appl. Pharm. , vol.222 , Issue.1 , pp. 1-16
    • Valerio, L.G.1    Arvidson, K.B.2    Chanderbhan, R.F.3    Contrera, J.F.4
  • 50
    • 84860999989 scopus 로고    scopus 로고
    • VirtualToxLab — A platform for estimating the toxic potential of drugs, chemicals and natural products
    • A.Vedani,, M.Dobler, and M.Smieško, (2012). VirtualToxLab — A platform for estimating the toxic potential of drugs, chemicals and natural products. Toxicol. Appl. Pharm. 261(2):142–153.
    • (2012) Toxicol. Appl. Pharm. , vol.261 , Issue.2 , pp. 142-153
    • Vedani, A.1    Dobler, M.2    Smieško, M.3
  • 51
    • 77949904980 scopus 로고    scopus 로고
    • The use of mechanisms and modes of toxic action in integrated testing strategies: The report and recommendations of a workshop held as part of the European union OSIRIS integrated project
    • J.A.Vonk,, R.Benigni,, M.Hewitt,, M.Nendza,, H.Segner,, van D.de Meent, and M.T.Cronin, (2009). The use of mechanisms and modes of toxic action in integrated testing strategies: The report and recommendations of a workshop held as part of the European union OSIRIS integrated project. Altern. Lab Anim. 37(5):557–571.
    • (2009) Altern. Lab Anim. , vol.37 , Issue.5 , pp. 557-571
    • Vonk, J.A.1    Benigni, R.2    Hewitt, M.3    Nendza, M.4    Segner, H.5    de Meent, D.6    Cronin, M.T.7
  • 52
    • 70350714470 scopus 로고    scopus 로고
    • Effects of methoxyisoflavone, ecdysterone, and sulfo-polysaccharide supplementation on training adaptations in resistance-trained males
    • C.Wilborn,, L.Taylor,, B.Campbell,, C.Kerksick,, C.Rasmussen,, M.Greenwood, and R.Kreider, (2006). Effects of methoxyisoflavone, ecdysterone, and sulfo-polysaccharide supplementation on training adaptations in resistance-trained males. J. Int. Soc. Sports Nutr. 3(2):19–27.
    • (2006) J. Int. Soc. Sports Nutr. , vol.3 , Issue.2 , pp. 19-27
    • Wilborn, C.1    Taylor, L.2    Campbell, B.3    Kerksick, C.4    Rasmussen, C.5    Greenwood, M.6    Kreider, R.7


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