Education and Risk of Dementia: Dose-Response Meta-Analysis of Prospective Cohort Studies

Molecular Neurobiology

Volumn 53, Issue 5, 2016, Pages 3113-3123

  Xu, Wei ^a   Tan, Lan ^a,b   Wang, Hui Fu ^b   Tan, Meng Shan ^a   Tan, Lin ^c   Li, Jie Qiong ^a   Zhao, Qing Fei ^a   Yu, Jin Tai ^a,d  

^a QINGDAO UNIVERSITY   (China)

^b NANJING MEDICAL UNIVERSITY   (China)

^c OCEAN UNIVERSITY OF CHINA   (China)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Dementia; Education; Meta analysis; Risk factor

Indexed keywords

AGE DISTRIBUTION; CARDIOVASCULAR RISK; DEMENTIA; DISEASE ASSOCIATION; DISEASE CLASSIFICATION; EDUCATIONAL STATUS; GEOGRAPHIC DISTRIBUTION; HUMAN; INTELLIGENCE QUOTIENT; LIFESTYLE; POPULATION RESEARCH; QUANTITATIVE ANALYSIS; REVIEW; RISK ASSESSMENT; RISK FACTOR; SEX DIFFERENCE; SOCIAL STATUS; SYSTEMATIC REVIEW; TREND STUDY; ALZHEIMER DISEASE; FEMALE; MALE; META ANALYSIS; MIDDLE AGED; PROSPECTIVE STUDY; PUBLISHING;

ALZHEIMER DISEASE; DEMENTIA; EDUCATIONAL STATUS; FEMALE; HUMANS; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; PUBLICATION BIAS; RISK FACTORS;

EID: 84929698739     PISSN: 08937648     EISSN: 15591182     Source Type: Journal    
DOI: 10.1007/s12035-015-9211-5     Document Type: Review

References (41)

1. Hurd MD, Martorell P, Delavande A, Mullen KJ, Langa KM (2013) Monetary costs of dementia in the United States. N Engl J Med 368(14):1326–1334. doi:10.1056/NEJMsa1204629
2. Brodaty H, Breteler MM, Dekosky ST, Dorenlot P, Fratiglioni L, Hock C, Kenigsberg PA, Scheltens P et al (2011) The world of dementia beyond 2020. J Am Geriatr Soc 59(5):923–927. doi:10.1111/j.1532-5415.2011.03365.x
3. Jiang T, Yu JT, Tian Y, Tan L (2013) Epidemiology and etiology of Alzheimer’s disease: from genetic to non-genetic factors. Curr Alzheimer Res 10(8):852–867
4. Christensen K, Thinggaard M, Oksuzyan A, Steenstrup T, Andersen-Ranberg K, Jeune B, McGue M, Vaupel JW (2013) Physical and cognitive functioning of people older than 90 years: a comparison of two Danish cohorts born 10 years apart. Lancet 382(9903):1507–1513. doi:10.1016/S0140-6736(13)60777-1
5. Matthews FE, Arthur A, Barnes LE, Bond J, Jagger C, Robinson L, Brayne C, Medical Research Council Cognitive F et al (2013) A two-decade comparison of prevalence of dementia in individuals aged 65 years and older from three geographical areas of England: results of the Cognitive Function and Ageing Study I and II. Lancet 382(9902):1405–1412. doi:10.1016/S0140-6736(13)61570-6
6. de la Fuente-Fernandez R (2006) Impact of neuroprotection on incidence of Alzheimer’s disease. PLoS One 1:e52. doi:10.1371/journal.pone.0000052
7. Cobb JL, Wolf PA, Au R, White R, D’Agostino RB (1995) The effect of education on the incidence of dementia and Alzheimer’s disease in the Framingham Study. Neurology 45(9):1707–1712
8. McDowell I, Xi G, Lindsay J, Tierney M (2007) Mapping the connections between education and dementia. J Clin Exp Neuropsychol 29(2):127–141. doi:10.1080/13803390600582420
9. Ott A, van Rossum CT, van Harskamp F, van de Mheen H, Hofman A, Breteler MM (1999) Education and the incidence of dementia in a large population-based study: the Rotterdam Study. Neurology 52(3):663–666
10. Crooks VC, Lubben J, Petitti DB, Little D, Chiu V (2008) Social network, cognitive function, and dementia incidence among elderly women. Am J Public Health 98(7):1221–1227. doi:10.2105/ajph.2007.115923
11. Bermejo-Pareja F, Benito-Leon J, Vega S, Medrano MJ, Roman GC (2008) Incidence and subtypes of dementia in three elderly populations of central Spain. J Neurol Sci 264(1–2):63–72. doi:10.1016/j.jns.2007.07.021
12. Karp A, Kareholt I, Qiu C, Bellander T, Winblad B, Fratiglioni L (2004) Relation of education and occupation-based socioeconomic status to incident Alzheimer’s disease. Am J Epidemiol 159(2):175–183
13. Kuller LH, Lopez OL, Newman A, Beauchamp NJ, Burke G, Dulberg C, Fitzpatrick A, Fried L et al (2003) Risk factors for dementia in the cardiovascular health cognition study. Neuroepidemiology 22(1):13–22
14. Lindsay J, Laurin D, Verreault R, Hebert R, Helliwell B, Hill GB, McDowell I (2002) Risk factors for Alzheimer’s disease: a prospective analysis from the Canadian Study of Health and Aging. Am J Epidemiol 156(5):445–453
15. Letenneur L, Launer LJ, Andersen K, Dewey ME, Ott A, Copeland JR, Dartigues JF, Kragh-Sorensen P et al (2000) Education and the risk for Alzheimer’s disease: sex makes a difference. EURODEM pooled analyses. EURODEM Incidence Research Group. Am J Epidemiol 151(11):1064–1071
16. Zhang M, Katzman R, Yu E, Liu W, Xiao SF, Yan H (1998) A preliminary analysis of incidence of dementia in Shanghai, China. Psychiatry Clin Neurosci 52(Suppl):S291–S294
17. Schmand B, Smit J, Lindeboom J, Smits C, Hooijer C, Jonker C, Deelman B (1997) Low education is a genuine risk factor for accelerated memory decline and dementia. J Clin Epidemiol 50(9):1025–1033
18. Al Hazzouri AZ, Haan MN, Neuhaus JM, Pletcher M, Peralta CA, Lopez L, Perez Stable EJ (2013) Cardiovascular risk score, cognitive decline, and dementia in older Mexican Americans: the role of sex and education. J Am Heart Assoc 2(2):e004978
19. Ravona-Springer R, Beeri MS, Goldbourt U (2013) Satisfaction with current status at work and lack of motivation to improve it during midlife is associated with increased risk for dementia in subjects who survived thirty-seven years later. J Alzheimers Dis JAD 36(4):769–780. doi:10.3233/jad-122422
20. Sasaki Y, Marioni R, Kasai M, Ishii H, Yamaguchi S, Meguro K (2011) Chronic kidney disease: a risk factor for dementia onset: a population-based study. The Osaki-Tajiri Project. J Am Geriatr Soc 59(7):1175–1181. doi:10.1111/j.1532-5415.2011.03477.x
21. Kukull WA, Higdon R, Bowen JD, McCormick WC, Teri L, Schellenberg GD, van Belle G, Jolley L et al (2002) Dementia and Alzheimer disease incidence: a prospective cohort study. Arch Neurol 59(11):1737–1746
22. Li S, Yan F, Li G, Chen C, Zhang W, Liu J, Jia X, Shen Y (2007) Is the dementia rate increasing in Beijing? Prevalence and incidence of dementia 10 years later in an urban elderly population. Acta Psychiatr Scand 115(1):73–79. doi:10.1111/j.1600-0447.2006.00859.x
23. Moher D, Liberati A, Tetzlaff J, Altman DG, Group P (2010) Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Int J Surg 8(5):336–341. doi:10.1016/j.ijsu.2010.02.007
24. Stroup DF, Berlin JA, Morton SC, Olkin I, Williamson GD, Rennie D, Moher D, Becker BJ et al (2000) Meta-analysis of observational studies in epidemiology: a proposal for reporting. Meta-analysis Of Observational Studies in Epidemiology (MOOSE) group. JAMA 283(15):2008–2012
25. Green S, McDonald S (2005) Cochrane Collaboration: more than systematic reviews? Intern Med J 35(1):3–4. doi:10.1111/j.1445-5994.2004.00747.x
26. Higgins JP, Thompson SG, Deeks JJ, Altman DG (2003) Measuring inconsistency in meta-analyses. BMJ (Clinical research ed) 327(7414):557–560. doi:10.1136/bmj.327.7414.557
27. DerSimonian R, Laird N (1986) Meta-analysis in clinical trials. Control Clin Trials 7(3):177–188
28. Greenland S, Longnecker MP (1992) Methods for trend estimation from summarized dose-response data, with applications to meta-analysis. Am J Epidemiol 135(11):1301–1309
29. Orsini N, Li R, Wolk A, Khudyakov P, Spiegelman D (2012) Meta-analysis for linear and nonlinear dose-response relations: examples, an evaluation of approximations, and software. Am J Epidemiol 175(1):66–73. doi:10.1093/aje/kwr265
30. Zhu K, van Hilten JJ, Marinus J (2014) Predictors of dementia in Parkinson’s disease; findings from a 5-year prospective study using the SCOPA-COG. Parkinsonism Relat Disord 20(9):980–985. doi:10.1016/j.parkreldis.2014.06.006
31. Katz MJ, Lipton RB, Hall CB, Zimmerman ME, Sanders AE, Verghese J, Dickson DW, Derby CA (2012) Age-specific and sex-specific prevalence and incidence of mild cognitive impairment, dementia, and Alzheimer dementia in blacks and whites: a report from the Einstein Aging Study. Alzheimer Dis Assoc Disord 26(4):335–343. doi:10.1097/WAD.0b013e31823dbcfc
32. Geerlings MI, Schoevers RA, Beekman AT, Jonker C, Deeg DJ, Schmand B, Ader HJ, Bouter LM et al (2000) Depression and risk of cognitive decline and Alzheimer’s disease. Results of two prospective community-based studies in The Netherlands. Br J Psychiatry J Ment Sci 176:568–575
33. Evans DA, Hebert LE, Beckett LA, Scherr PA, Albert MS, Chown MJ, Pilgrim DM, Taylor JO (1997) Education and other measures of socioeconomic status and risk of incident Alzheimer disease in a defined population of older persons. Arch Neurol 54(11):1399–1405
34. Wilson RS, Bennett DA, Bienias JL, Aggarwal NT, Mendes De Leon CF, Morris MC, Schneider JA, Evans DA (2002) Cognitive activity and incident AD in a population-based sample of older persons. Neurology 59(12):1910–1914
35. Gureje O, Ogunniyi A, Kola L, Abiona T (2011) Incidence of and risk factors for dementia in the Ibadan study of aging. J Am Geriatr Soc 59(5):869–874. doi:10.1111/j.1532-5415.2011.03374.x
36. Kaup AR, Simonsick EM, Harris TB, Satterfield S, Metti AL, Ayonayon HN, Rubin SM, Yaffe K (2013) Older adults with limited literacy are at increased risk for likely dementia. J Gerontol A: Biol Med Sci. doi:10.1093/gerona/glt176
37. Bennett DA, Schneider JA, Wilson RS, Bienias JL, Arnold SE (2005) Education modifies the association of amyloid but not tangles with cognitive function. Neurology 65(6):953–955. doi:10.1212/01.wnl.0000176286.17192.69
38. Rolstad S, Nordlund A, Eckerstrom C, Gustavsson MH, Blennow K, Olesen PJ, Zetterberg H, Wallin A (2010) High education may offer protection against tauopathy in patients with mild cognitive impairment. J Alzheimers Dis JAD 21(1):221–228. doi:10.3233/JAD-2010-091012
39. Foubert-Samier A, Catheline G, Amieva H, Dilharreguy B, Helmer C, Allard M, Dartigues JF (2012) Education, occupation, leisure activities, and brain reserve: a population-based study. Neurobiology of aging 33(2):423 e415–425. doi:10.1016/j.neurobiolaging.2010.09.023
40. Liu Y, Julkunen V, Paajanen T, Westman E, Wahlund LO, Aitken A, Sobow T, Mecocci P et al (2012) Education increases reserve against Alzheimer’s disease—evidence from structural MRI analysis. Neuroradiology 54(9):929–938. doi:10.1007/s00234-012-1005-0
41. Ibrahim CV, Demirkan A, Isaacs A, Amin N, Van Swieten J, Oostra B, Van Duijn C (2012) Phosphosphingolipid levels are associated with cognitive function and level of education in healthy subjects. Alzheimers Dement 8(4):P275