Oxidized glutathione (GSSG) inhibits epithelial sodium channel activity in primary alveolar epithelial cells

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 308, Issue 9, 2015, Pages L943-L952

  Downs, Charles A ^b   Kreiner, Lisa ^a   Zhao, Xing Ming ^d   Trac, Phi ^a   Johnson, Nicholle M ^a   Hansen, Jason M ^a,c   Brown, Lou Ann ^a,c   Helms, My N ^a,c  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b EMORY UNIVERSITY   (United States)

^c CHILDREN'S HEALTHCARE OF ATLANTA   (United States)

^d TONGJI UNIVERSITY   (China)

Author keywords

Alveolar flooding; Cys thiol; Oxidative stress; Redox potential

Indexed keywords

CYSTEINE; EPITHELIAL SODIUM CHANNEL; GLUTATHIONE; GLUTATHIONE DISULFIDE; GLUTATHIONE ETHYL ESTER; N ETHYLMALEIMIDE; REACTIVE OXYGEN METABOLITE; ACID SENSING ION CHANNEL; ANTIOXIDANT; EPITHELIAL SODIUM CHANNEL BLOCKING AGENT; HYDROGEN PEROXIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOCHEMICAL ANALYSIS; CELL ISOLATION; CLINICAL ASSESSMENT; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; FEMALE; FLUID BALANCE; IN VIVO STUDY; ION TRANSPORT; LUNG ALVEOLUS CELL TYPE 2; LUNG ALVEOLUS EPITHELIUM CELL; LUNG FLUID; LUNG PARENCHYMA; MALE; NONHUMAN; OXIDATION KINETICS; OXIDATION REDUCTION POTENTIAL; OXIDATION REDUCTION STATE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN PROCESSING; RAT; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; SINGLE CHANNEL PATCH CLAMP; ANIMAL; C57BL MOUSE; CELL CULTURE; CHEMISTRY; CYTOLOGY; EPITHELIUM CELL; LUNG ALVEOLUS; METABOLISM; MOUSE; OXIDATION REDUCTION REACTION; PATCH CLAMP TECHNIQUE; RESPIRATORY TRACT MUCOSA; SPRAGUE DAWLEY RAT;

ACID SENSING ION CHANNELS; ANIMALS; ANTIOXIDANTS; CELLS, CULTURED; EPITHELIAL CELLS; EPITHELIAL SODIUM CHANNEL BLOCKERS; EPITHELIAL SODIUM CHANNELS; FEMALE; GLUTATHIONE DISULFIDE; HYDROGEN PEROXIDE; MALE; MICE; MICE, INBRED C57BL; OXIDATION-REDUCTION; OXIDATIVE STRESS; PATCH-CLAMP TECHNIQUES; PULMONARY ALVEOLI; RATS; RATS, SPRAGUE-DAWLEY; RESPIRATORY MUCOSA;

EID: 84929678053     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00213.2014     Document Type: Article

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