The role of deimination as a response to trauma and hypoxic injury in the developing CNS

Protein Deimination in Human Health and Disease

Volumn , Issue , 2014, Pages 281-294

  Ferretti, Patrizia ^a   Lange, Sigrun ^a,b   U, Kin Pong ^a   Raivich, Gennadij ^b  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Brain; Chick; Citrullination; Deimination; Development; Human; Hypoxia ischemia; Injury; Mouse; Neonate; Neural stem cell; PAD inhibitor; Peptidylarginine deiminase (PAD); Spinal cord; Stroke; Trauma

Indexed keywords

EID: 84929672641     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-1-4614-8317-5_15     Document Type: Chapter

References (48)

1. Balandraud N, Gouret P, Danchin EG, Blanc M, Zinn D, Roudier J, Pontarotti P. (2005). A rigorous method for multigenic families? functional annotation: the peptidyl arginine deiminase (PADs) proteins family example. BMC Genomics 6: 153
2. Beattie MS, Farooqui AA, Bresnahan JC. (2000). Review of current evidence for apoptosis after spinal cord injury. J Neurotrauma 17: 915-925
3. Berry M, Logan A. (2000). Response of the central nervous system to penetrating injury: scarring and regeneration of axons. In: Crockard A, et al (eds) Neurosurgery. The scientific basis of clinical practice, vol 1. Blackwell Scientific, Oxford, pp 479-498
4. Brahmajosyula M, Miyake M. (2011). Localization and expression of peptidylarginine deiminase 4 (PAD4) in mammalian oocytes and preimplantation embryos. Zygote: 1-11
5. Brahmajosyula M, Miyake M. (2012). Role of peptidylarginine deiminase 4 (PAD4) in pig parthenogenetic preimplantation embryonic development. Zygote: 1-9
6. Chavanas S, Mechin MC, Takahara H, Kawada A, Nachat R, Serre G, Simon M. (2004). Comparative analysis of the mouse and human peptidylarginine deiminase gene clusters reveals highly conserved non-coding segments and a new human gene, PADI6. Gene 330: 19-27
7. Clarke JDW, Ferretti P. (1998). CNS regeneration in lower vertebrates. In: Ferretti P, Géraudie J (eds) Cellular and molecular basis of regeneration: from invertebrates to humans. Wiley, Chichester, England, pp 255-269
8. Emery E, Aldana P, Bunge MB, Puckett W, Srinivasan A, Keane RW, Bethea J, Levi AD. (1998). Apoptosis after traumatic human spinal cord injury. J Neurosurg 89: 911-920
9. Esposito G, Vitale AM, Leijten FP, Strik AM, Koonen-Reemst AM, Yurttas P, Robben TJ, Coonrod S, Gossen JA. (2007). Peptidylarginine deiminase (PAD) 6 is essential for oocyte cytoskeletal sheet formation and female fertility. Mol Cell Endocrinol 273: 25-31
10. Ferretti P, Whalley K. (2008). Molecular and cellular basis of regeneration and tissue repair: successful neural regeneration in amniotes: the developing chick spinal cord. Cell Mol Life Sci 65: 45-53
11. Ferretti P, Zhang F, O'Neill P. (2003). Changes in spinal cord regeneration through phylogenesis and development: lessons to be learnt. Dev Dyn 226: 245-256
12. Franklin-Tong VE, Gourlay CW. (2008). A role for actin in regulating apoptosis/programmed cell death: evidence spanning yeast, plants and animals. Biochem J 413: 389-404
13. Gyorgy B, Toth E, Tarcsa E, Falus A, Buzas EI. (2006). Citrullination: a posttranslational modification in health and disease. Int J Biochem Cell Biol 38: 1662-1677
14. Hasan SJ, Nelson BH, Valenzuela JI, Keirstead HS, Shull SE, Ethell DW, Steeves JD. (1991). Functional repair of transected spinal cord in embryonic chick. Restor Neurol Neurosci 2: 137-154
15. Hasan SJ, Keirstead HS, Muir GD, Steeves JD. (1993). Axonal regeneration contributes to repair of injured brain stem spinal neurons in embryonic chick. J Neurosci 13: 492-507
16. Hristova M, Cuthill D, Zbarsky V, Acosta-Saltos A, Wallace A, Blight K, Buckley SM, Peebles D, Heuer H, Waddington SN, Raivich G. (2010). Activation and deactivation of periventricular white matter phagocytes during postnatal mouse development. Glia 58: 11-28
17. Inman D, Guth L, Steward O. (2002). Genetic infl uences on secondary degeneration and wound healing following spinal cord injury in various strains of mice. J Comp Neurol 451: 225-235
18. Kan R, Jin M, Subramanian V, Causey CP, Thompson PR, Coonrod SA. (2012). Potential role for PADI-mediated histone citrullination in preimplantation development. BMC Dev Biol 12: 19
19. Keilhoff G, Prell T, Langnaese K, Mawrin C, Simon M, Fansa H, Nicholas AP. (2008). Expression pattern of peptidylarginine deiminase in rat and human Schwann cells. Dev Neurobiol 68: 101-114
20. Kendall GS, Hirstova M, Horn S, Dafou D, Acosta-Saltos A, Almolda B, Zbarsky V, Rumajogee P, Heuer H, Castellano B, Pfeffer K, Nedospasov SA, Peebles DM, Raivich G. (2011). TNF gene cluster deletion abolishes lipopolysaccharide-mediated sensitization of the neonatal brain to hypoxic ischemic insult. Lab Invest 91: 328-341
21. Kendall GS, Hristova M, Zbarsky V, Clements A, Peebles DM, Robertson NJ, Raivich G. (2011). Distribution of pH changes in mouse neonatal hypoxic-ischaemic insult. Dev Neurosci 33: 505-518
22. Kumral A, Tuzun F, Tugyan K, Ozbal S, Yilmaz O, Yesilirmak CD, Duman N, Ozkan H. (2012). Role of epigenetic regulatory mechanisms in neonatal hypoxic-ischemic brain injury. Early Hum Dev 89: 165-173
23. Lange S, Gogel S, Leung KY, Vernay B, Nicholas AP, Causey CP, Thompson PR, Greene ND, Ferretti P. (2011). Protein deiminases: new players in the developmentally regulated loss of neural regenerative ability. Dev Biol 355: 205-214
24. Luo Y, Knuckley B, Lee YH, Stallcup MR, Thompson PR. (2006). A fluoroacetamidine-based inactivator of protein arginine deiminase 4: design, synthesis, and in vitro and in vivo evaluation. J Am Chem Soc 128: 1092-1093
25. Mastronardi FG, Moscarello MA. (2005). Molecules affecting myelin stability: a novel hypothesis regarding the pathogenesis of multiple sclerosis. J Neurosci Res 80: 301-308
26. Mastronardi FG, Wood DD, Mei J, Raijmakers R, Tseveleki V, Dosch HM, Probert L, Casaccia-Bonnefil P, Moscarello MA. (2006). Increased citrullination of histone H3 in multiple sclerosis brain and animal models of demyelination: a role for tumor necrosis factor-induced peptidylarginine deiminase 4 translocation. J Neurosci 26: 11387-11396
27. McBride CB, McPhail LT, Vanderluit JL, Tetzlaff W, Steeves JD. (2003). Caspase inhibition attenuates transection-induced oligodendrocyte apoptosis in the developing chick spinal cord. Mol Cell Neurosci 23: 383-397
28. Musse AA, Li Z, Ackerley CA, Bienzle D, Lei H, Poma R, Harauz G, Moscarello MA, Mastronardi FG. (2008). Peptidylarginine deiminase 2 (PAD2) overexpression in transgenic mice leads to myelin loss in the central nervous system. Dis Model Mech 1: 229-240
29. Nicholas AP, King JL, Sambandam T, Echols JD, Gupta KB, McInnis C, Whitaker JN. (2003). Immunohistochemical localization of citrullinated proteins in adult rat brain. J Comp Neurol 459: 251-266
30. Perlman JM. (2006). Intervention strategies for neonatal hypoxic-ischemic cerebral injury. Clin Ther 28: 1353-1365
31. Raijmakers R, Vogelzangs J, Raats J, Panzenbeck M, Corby M, Jiang H, Thibodeau M, Haynes N, van Venrooij WJ, Pruijn GJ, Werneburg B. (2006). Experimental autoimmune encephalomyelitis induction in peptidylarginine deiminase 2 knockout mice. J Comp Neurol 498: 217-226
32. Rice JE 3rd, Vannucci RC, Brierley JB. (1981). The infl uence of immaturity on hypoxic-ischemic brain damage in the rat. Ann Neurol 9: 131-141
33. Rovini A, Savry A, Braguer D, Carre M. (2011). Microtubule-Targeted agents: when mitochondria become essential to chemotherapy. Biochim Biophys Acta 1807: 679-688
34. Shanshiashvili LV, Kalandadze IV, Ramsden JJ, Mikeladze DG. (2012). Adhesive properties and infl ammatory potential of citrullinated myelin basic protein peptide 45-89. Neurochem Res 37: 1959-1966
35. Shimada N, Handa S, Uchida Y, Fukuda M, Maruyama N, Asaga H, Choi EK, Lee J, Ishigami A. (2009). Developmental and age-related changes of peptidylarginine deiminase 2 in the mouse brain. J Neurosci Res 88: 798-806
36. Shimizu I, Oppenheim RW, Obrien M, Shneiderman A. (1990). Anatomical and functional recovery following spinal cord transection in the chick embryo. J Neurobiol 21: 918-937
37. Sholomenko GN, Delaney KR. (1998). Restitution of functional neural connections in chick embryos assessed in vitro after spinal cord transection in Ovo. Exp Neurol 154: 430-451
38. Tanaka EM, Ferretti P. (2009). Considering the evolution of regeneration in the central nervous system. Nat Rev Neurosci 10: 713-723
39. Tsuji Y, Akiyama M, Arita K, Senshu T, Shimizu H. (2003). Changing pattern of deiminated proteins in developing human epidermis. J Invest Dermatol 120: 817-822
40. Velardo MJ, Reier PJ, Anderson DK. (2000). Spinal cord injury. In: Crockard A, et al (eds) Neurosurgery. The scientific basis of clinical practice, vol 1. Blackwell Scientific, Oxford, pp 499-515
41. Vossenaar ER, Zendman AJ, van Venrooij WJ, Pruijn GJ. (2003). PAD, a growing family of citrullinating enzymes: genes, features and involvement in disease. Bioessays 25: 1106-1118
42. Wang Y, Wysocka J, Sayegh J, Lee YH, Perlin JR, Leonelli L, Sonbuchner LS, McDonald CH, Cook RG, Dou Y, Roeder RG, Clarke S, Stallcup MR, Allis CD, Coonrod SA. (2004). Human PAD4 regulates histone arginine methylation levels via demethylimination. Science 306: 279-283
43. Whalley K, O'Neill P, Ferretti P. (2006). Changes in response to spinal cord injury with development: vascularization, haemorrhage and apoptosis. Neuroscience 137: 821-832
44. Whalley K, Gogel S, Lange S, Ferretti P. (2009). Changes in progenitor populations and ongoing neurogenesis in the regenerating chick spinal cord. Dev Biol 332: 234-245
45. Wood DD, Ackerley CA, Brand B, Zhang L, Raijmakers R, Mastronardi FG, Moscarello MA. (2008). Myelin localization of peptidylarginine deiminases 2 and 4: comparison of PAD2 and PAD4 activities. Lab Invest 88: 354-364
46. Yurttas P, Vitale AM, Fitzhenry RJ, Cohen-Gould L, Wu W, Gossen JA, Coonrod SA. (2008). Role for PADI6 and the cytoplasmic lattices in ribosomal storage in oocytes and translational control in the early mouse embryo. Development 135: 2627-2636
47. Zhang Z, Fujiki M, Guth L, Steward O. (1996). Genetic infl uences on cellular reactions to spinal cord injury: a wound-healing response present in normal mice is impaired in mice carrying a mutation (WldS) that causes delayed Wallerian degeneration. J Comp Neurol 371: 485-495
48. Zhang X, Bolt M, Guertin MJ, Chen W, Zhang S, Cherrington BD, Slade DJ, Dreyton CJ, Subramanian V, Bicker KL, Thompson PR, Mancini MA, Lis JT, Coonrod SA. (2012). Peptidylarginine deiminase 2-catalyzed histone H3 arginine 26 citrullination facilitates estrogen receptor alpha target gene activation. Proc Natl Acad Sci USA 109: 13331-13336