Peptidylarginine deiminase 2 (PAD2) overexpression in transgenic mice leads to myelin loss in the central nervous system

DMM Disease Models and Mechanisms

Volumn 1, Issue 4-5, 2008, Pages 229-240

  Musse, Abdiwahab A ^a   Zhen, Li ^b   Ackerley, Cameron A ^b   Bienzle, Dorothee ^c   Lei, Helena ^b   Poma, Roberto ^c   Harauz, George ^a   Moscarello, Mario A ^b   Mastronardi, Fabrizio G ^b  

^a UNIVERSITY OF GUELPH   (Canada)

^b HOSPITAL FOR SICK CHILDREN   (Canada)

^c UNIVERSITY OF GUELPH   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CD68 ANTIGEN; CITRULLINE; COMPLEMENTARY DNA; GLIAL FIBRILLARY ACIDIC PROTEIN; ISOENZYME; MYELIN; MYELIN BASIC PROTEIN; PEPTIDYLARGININE DEIMINASE 2; PROTEIN ARGININE DEIMINASE; PROTEIN ARGININE DEIMINASE 4; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; HYDROLASE; MESSENGER RNA; PROTEIN-ARGININE DEIMINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTROCYTOSIS; BRAIN HOMOGENATE; CELL INFILTRATION; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; CORRELATION ANALYSIS; DEMYELINATION; ENZYME ACTIVITY; GENE OVEREXPRESSION; GENETIC CODE; HETEROZYGOSITY; HISTOPATHOLOGY; HOMOZYGOSITY; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; MACROPHAGE ACTIVATION; MOUSE; MULTIPLE SCLEROSIS; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN STABILITY; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSGENIC MOUSE; TRANSMISSION ELECTRON MICROSCOPY; WHITE MATTER; ANIMAL; GENETICS; METABOLISM; MYELIN SHEATH; PATHOLOGY; PHENOTYPE;

MUS; MUS MUSCULUS;

ANIMALS; CENTRAL NERVOUS SYSTEM; HYDROLASES; MICE; MICE, TRANSGENIC; MICROSCOPY, ELECTRON, TRANSMISSION; MYELIN SHEATH; PHENOTYPE; RNA, MESSENGER; TUMOR NECROSIS FACTOR-ALPHA;

EID: 64249156653     PISSN: 17548403     EISSN: 17548411     Source Type: Journal    
DOI: 10.1242/dmm.000729     Document Type: Article

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