Nitrite-mediated renal vasodilatation is increased during ischemic conditions via cGMP-independent signaling

Free Radical Biology and Medicine

Volumn 84, Issue , 2015, Pages 154-160

  Liu, Ming ^a   Zollbrecht, Christa ^a   Peleli, Maria ^a   Lundberg, Jon O ^a   Weitzberg, Eddie ^a   Carlström, Mattias ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

cGMP independent; Free radicals; Inorganic nitrite; Interlobar artery; Ischemia; Kidney; Nitric oxide; Renal vasculature; Xanthine oxidoreductase

Indexed keywords

1H 1,2,4 OXADIAZOLO[4,3 A]QUINOXALIN 1 ONE; ALDEHYDE DEHYDROGENASE; ALDEHYDE OXIDASE; ALLOPURINOL; CYCLIC GMP; FEBUXOSTAT; NITRIC OXIDE SYNTHASE; NITRITE; REACTIVE NITROGEN SPECIES; XANTHINE OXIDASE;

ACIDOSIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ENZYME INHIBITION; HYPOXIA; KIDNEY ISCHEMIA; MALE; MOUSE; NITROSATION; NONHUMAN; OXYGEN TENSION; PH; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; VASODILATATION; ANIMAL; C57BL MOUSE; CELL HYPOXIA; ISCHEMIA; KIDNEY; METABOLISM; SECOND MESSENGER; VASCULARIZATION;

MUS;

ANIMALS; CELL HYPOXIA; CYCLIC GMP; ISCHEMIA; KIDNEY; MALE; MICE, INBRED C57BL; NITRITES; SECOND MESSENGER SYSTEMS; VASODILATION; XANTHINE OXIDASE;

EID: 84929660676     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2015.03.025     Document Type: Article

References (33)

1. KU Eckardt, WM Bernhardt, A Weidemann, C Warnecke, C Rosenberger, MS Wiesener, and C. Willam Role of hypoxia in the pathogenesis of renal disease Kidney Int Suppl 99 2005 S46 S51
2. JO Lundberg, E Weitzberg, and MT. Gladwin The nitrate-nitrite-nitric oxide pathway in physiology and therapeutics Nat Rev Drug Discovery 7 2008 156 167
3. JO Lundberg, M Carlstrom, FJ Larsen, and E. Weitzberg Roles of dietary inorganic nitrate in cardiovascular health and disease Cardiovasc Res 89 2011 525 532
4. N Castiglione, S Rinaldo, G Giardina, V Stelitano, and F. Cutruzzola Nitrite and nitrite reductases: from molecular mechanisms to significance in human health and disease Antioxid Redox Signaling 17 2012 684 716
5. SA Omar, E Artime, and AJ. Webb A comparison of organic and inorganic nitrates/nitrites Nitric Oxide 26 2012 229 240
6. T Rassaf, U Flogel, C Drexhage, U Hendgen-Cotta, M Kelm, and J. Schrader Nitrite reductase function of deoxymyoglobin: oxygen sensor and regulator of cardiac energetics and function Circ Res 100 2007 1749 1754
7. S Shiva, Z Huang, R Grubina, J Sun, LA Ringwood, PH MacArthur, X Xu, E Murphy, VM Darley-Usmar, and MT. Gladwin Deoxymyoglobin is a nitrite reductase that generates nitric oxide and regulates mitochondrial respiration Circ Res 100 2007 654 661
8. H Li, TK Kundu, and JL. Zweier Characterization of the magnitude and mechanism of aldehyde oxidase-mediated nitric oxide production from nitrite J Biol Chem 284 2009 33850 33858
9. NH Golwala, C Hodenette, SN Murthy, BD Nossaman, and PJ. Kadowitz Vascular responses to nitrite are mediated by xanthine oxidoreductase and mitochondrial aldehyde dehydrogenase in the rat Can J Physiol Pharmacol 87 2009 1095 1101
10. K Sonoda, K Ohtake, Y Kubo, H Uchida, M Uchida, H Natsume, M Kobayashi, and J. Kobayashi Aldehyde dehydrogenase 2 partly mediates hypotensive effect of nitrite on L-NAME-induced hypertension in normoxic rat Clin Exp Hypertens 36 2014 410 418
11. S Arif, A Borgognone, EL Lin, AG O'Sullivan, V Sharma, NE Drury, A Menon, P Nightingale, J Mascaro, RS Bonser, JD Horowitz, M Feelisch, MP Frenneaux, and M. Madhani Role of aldehyde dehydrogenase in hypoxic vasodilator effects of nitrite in rats and humans Br J Pharmacol 2015 in press
12. H Li, A Samouilov, X Liu, and JL. Zweier Characterization of the magnitude and kinetics of xanthine oxidase-catalyzed nitrate reduction: evaluation of its role in nitrite and nitric oxide generation in anoxic tissues Biochemistry 42 2003 1150 1159
13. EA Jansson, L Huang, R Malkey, M Govoni, C Nihlen, A Olsson, M Stensdotter, J Petersson, L Holm, E Weitzberg, and JO. Lundberg A mammalian functional nitrate reductase that regulates nitrite and nitric oxide homeostasis Nat Chem Biol 4 2008 411 417
14. AF Vanin, LM Bevers, A Slama-Schwok, and EE. van Faassen Nitric oxide synthase reduces nitrite to NO under anoxia Cell Mol Life Sci 64 2007 96 103
15. A Modin, H Bjorne, M Herulf, K Alving, E Weitzberg, and JO. Lundberg Nitrite-derived nitric oxide: a possible mediator of 'acidic-metabolic' vasodilation Acta Physiol Scand 171 2001 9 16
16. JH Crawford, TS Isbell, Z Huang, S Shiva, BK Chacko, AN Schechter, VM Darley-Usmar, JD Kerby, JD Lang Jr, D Kraus, C Ho, MT Gladwin, and RP. Patel Hypoxia, red blood cells, and nitrite regulate NO-dependent hypoxic vasodilation Blood 107 2006 566 574
17. AB Milsom, NS Patel, E Mazzon, P Tripatara, A Storey, H Mota-Filipe, B Sepodes, AJ Webb, S Cuzzocrea, AJ Hobbs, C Thiemermann, and A. Ahluwalia Role for endothelial nitric oxide synthase in nitrite-induced protection against renal ischemia-reperfusion injury in mice Nitric Oxide 22 2010 141 148
18. P Tripatara, NS Patel, A Webb, K Rathod, FM Lecomte, E Mazzon, S Cuzzocrea, MM Yaqoob, A Ahluwalia, and C. Thiemermann Nitrite-derived nitric oxide protects the rat kidney against ischemia/reperfusion injury in vivo: role for xanthine oxidoreductase J Am Soc Nephrol 18 2007 570 580
19. M Carlstrom, M Liu, T Yang, C Zollbrecht, L Huang, M Peleli, S Borniquel, H Kishikawa, M Hezel, AE Persson, E Weitzberg, and JO. Lundberg Cross-talk between nitrate-nitrite-NO and NO synthase pathways in control of vascular NO homeostasis Antioxid Redox Signaling 2014 in press
20. MJ Mulvany, and W. Halpern Contractile properties of small arterial resistance vessels in spontaneously hypertensive and normotensive rats Circ Res 41 1977 19 26
21. T Yang, M Peleli, C Zollbrecht, A Giulietti, N Terrando, JO Lundberg, E Weitzberg, and M. Carlstrom Inorganic nitrite attenuates NADPH oxidase-derived superoxide generation in activated macrophages via a nitric oxide-dependent mechanism Free Radic Biol Med 83 2015 159 166
22. D. Jourd'heuil Increased nitric oxide-dependent nitrosylation of 4,5-diaminofluorescein by oxidants: implications for the measurement of intracellular nitric oxide Free Radic Biol Med 33 2002 676 684
23. MG Espey, DD Thomas, KM Miranda, and DA. Wink Focusing of nitric oxide mediated nitrosation and oxidative nitrosylation as a consequence of reaction with superoxide Proc Natl Acad Sci USA 99 2002 11127 11132
24. MM Cortese-Krott, A Rodriguez-Mateos, GG Kuhnle, G Brown, M Feelisch, and M. Kelm A multilevel analytical approach for detection and visualization of intracellular NO production and nitrosation events using diaminofluoresceins Free Radic Biol Med 53 2012 2146 2158
25. M Umbrello, A Dyson, BB Pinto, BO Fernandez, V Simon, M Feelisch, and M. Singer Short-term hypoxic vasodilation in vivo is mediated by bioactive nitric oxide metabolites, rather than free nitric oxide derived from haemoglobin-mediated nitrite reduction J Physiol 592 2014 1061 1075
26. LJ. Ignarro After 130 years, the molecular mechanism of action of nitroglycerin is revealed Proc Natl Acad Sci USA 99 2002 7816 7817
27. Z Chen, J Zhang, and JS. Stamler Identification of the enzymatic mechanism of nitroglycerin bioactivation Proc Natl Acad Sci USA 99 2002 8306 8311
28. H Li, H Cui, TK Kundu, W Alzawahra, and JL. Zweier Nitric oxide production from nitrite occurs primarily in tissues not in the blood: critical role of xanthine oxidase and aldehyde oxidase J Biol Chem 283 2008 17855 17863
29. A Webb, R Bond, P McLean, R Uppal, N Benjamin, and A. Ahluwalia Reduction of nitrite to nitric oxide during ischemia protects against myocardial ischemia-reperfusion damage Proc Natl Acad Sci USA 101 2004 13683 13688
30. HA Omar, and MS. Wolin Endothelium-dependent and independent cGMP mechanisms appear to mediate O2 responses in calf pulmonary resistance arteries Am J Physiol 262 1992 L560 L565
31. MH Yousif, MA Oriowo, and KI. Williams Sodium nitroprusside-induced cGMP-independent vasodilator responses in the perfused rabbit ovarian vascular bed Pharmacol Res 38 1998 381 386
32. CJ Mingone, SA Gupte, T Iesaki, and MS. Wolin Hypoxia enhances a cGMP-independent nitric oxide relaxing mechanism in pulmonary arteries Am J Physiol Lung Cell Mol Physiol 285 2003 L296 L304
33. M Brini, and E. Carafoli Calcium pumps in health and disease Physiol Rev 89 2009 1341 1378