Blockage of P2X7 attenuates acute lung injury in mice by inhibiting NLRP3 inflammasome

International Immunopharmacology

Volumn 27, Issue 1, 2015, Pages 38-45

  Wang, Shuang ^a   Zhao, Jijun ^a   Wang, Hongyue ^a   Liang, Yingjie ^a   Yang, Niansheng ^a   Huang, Yuefang ^a  

^a SUN YAT SEN UNIVERSITY   (China)

Author keywords

Acute lung injury; IL 1 ; Inflammasome; Neutrophils; P2X7

Indexed keywords

3 [[5 (2,3 DICHLOROPHENYL) 1H TETRAZOL 1 YL]METHYL]PYRIDINE; BRILLIANT BLUE G; CRYOPYRIN; GAMMA INTERFERON; INFLAMMASOME; INTERLEUKIN 10; INTERLEUKIN 17; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; PURINERGIC P2X RECEPTOR ANTAGONIST; UNCLASSIFIED DRUG; 3-(5-(2,3-DICHLOROPHENYL)-1H-TETRAZOL-1-YL)METHYLPYRIDINE; CARRIER PROTEIN; CIAS1 PROTEIN, MOUSE; CYTOKINE; PURINERGIC P2X7 RECEPTOR; PYRIDINE DERIVATIVE; TETRAZOLE DERIVATIVE;

ACUTE LUNG INJURY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW DERIVED MACROPHAGE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG EFFICACY; IN VIVO STUDY; INVESTIGATIVE PROCEDURES; MALE; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PRIORITY JOURNAL; UPREGULATION; ANIMAL; C57BL MOUSE; CHEMICALLY INDUCED; DISEASE MODEL; DRUG EFFECTS; HUMAN; IMMUNOLOGY; MACROPHAGE; METABOLISM; NEUTROPHIL;

ACUTE LUNG INJURY; ANIMALS; CARRIER PROTEINS; CYTOKINES; DISEASE MODELS, ANIMAL; HUMANS; INFLAMMASOMES; LIPOPOLYSACCHARIDES; MACROPHAGES; MALE; MICE; MICE, INBRED C57BL; NEUTROPHILS; PURINERGIC P2X RECEPTOR ANTAGONISTS; PYRIDINES; RECEPTORS, PURINERGIC P2X7; TETRAZOLES;

EID: 84929660143     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2015.04.035     Document Type: Article

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