P2X7 blockade attenuates murine lupus nephritis by inhibiting activation of the NLRP3/ASC/Caspase 1 pathway

Arthritis and Rheumatism

Volumn 65, Issue 12, 2013, Pages 3176-3185

  Zhao, Jijun ^a   Wang, Hongyue ^a   Dai, Chao ^b   Wang, Hongyang ^b   Zhang, Hui ^a   Huang, Yuefang ^a   Wang, Shuang ^a   Gaskin, Felicia ^b   Yang, Niansheng ^a   Fu, Shu Man ^b  

^a SUN YAT SEN UNIVERSITY   (China)

^b UNIVERSITY OF VIRGINIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; BRILLIANT BLUE; CARRIER PROTEINS AND BINDING PROTEINS; CRYOPYRIN; DOUBLE STRANDED DNA ANTIBODY; INTERLEUKIN 17; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; PROTEIN ASC; PURINERGIC P2X RECEPTOR; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; CARRIER PROTEIN; CIAS1 PROTEIN, MOUSE; COOMASSIE BRILLIANT BLUE; CYTOSKELETON PROTEIN; FUCHSINE; INFLAMMASOME; PURINERGIC P2 RECEPTOR ANTAGONIST; PURINERGIC P2X7 RECEPTOR; PYCARD PROTEIN, MOUSE; APOPTOSIS REGULATORY PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY BLOOD LEVEL; ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; ENZYME ACTIVATION; FEMALE; IMMUNE COMPLEX DEPOSITION; IN VIVO STUDY; KIDNEY INJURY; LIFESPAN; LUPUS ERYTHEMATOSUS NEPHRITIS; MORTALITY; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; SURVIVAL RATE; TH17 CELL; UPREGULATION; ANIMAL; DRUG EFFECT; KIDNEY; LONGEVITY; METABOLISM; SEVERITY OF ILLNESS INDEX; SIGNAL TRANSDUCTION; DRUG EFFECTS; LUPUS NEPHRITIS;

ANIMALS; CARRIER PROTEINS; CASPASE 1; CYTOSKELETAL PROTEINS; FEMALE; INFLAMMASOMES; KIDNEY; LONGEVITY; LUPUS NEPHRITIS; MICE; PURINERGIC P2 RECEPTOR ANTAGONISTS; RECEPTORS, PURINERGIC P2X7; ROSANILINE DYES; SEVERITY OF ILLNESS INDEX; SIGNAL TRANSDUCTION; APOPTOSIS REGULATORY PROTEINS;

EID: 84889048300     PISSN: 00043591     EISSN: 15290131     Source Type: Journal    
DOI: 10.1002/art.38174     Document Type: Article

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