메뉴 건너뛰기




Volumn 134, Issue , 2015, Pages 22-30

Flavonoid Chrysin prevents age-related cognitive decline via attenuation of oxidative stress and modulation of BDNF levels in aged mouse brain

Author keywords

Aging; Antioxidant; BDNF; Flavonoid; Memory

Indexed keywords

ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ANTIOXIDANT; BRAIN DERIVED NEUROTROPHIC FACTOR; CATALASE; CHRYSIN; FLAVONOID; GLUTATHIONE PEROXIDASE; REACTIVE OXYGEN METABOLITE; SCAVENGER; SODIUM ION; SUPEROXIDE DISMUTASE; BIOLOGICAL MARKER;

EID: 84929659444     PISSN: 00913057     EISSN: 18735177     Source Type: Journal    
DOI: 10.1016/j.pbb.2015.04.010     Document Type: Article
Times cited : (108)

References (36)
  • 1
    • 0021318441 scopus 로고
    • Catalase in vitro
    • H. Aebi Catalase in vitro Methods Enzymol 105 1984 121 126
    • (1984) Methods Enzymol , vol.105 , pp. 121-126
    • Aebi, H.1
  • 2
    • 84902245181 scopus 로고    scopus 로고
    • Chrysin, an anti-inflammatory molecule, abrogates renal dysfunction in type 2 diabetic rats
    • A. Ahad, A.A. Ganai, M. Mujeeb, and W.A. Siddiqui Chrysin, an anti-inflammatory molecule, abrogates renal dysfunction in type 2 diabetic rats Toxicol Appl Pharmacol 279 2014 1 7
    • (2014) Toxicol Appl Pharmacol , vol.279 , pp. 1-7
    • Ahad, A.1    Ganai, A.A.2    Mujeeb, M.3    Siddiqui, W.A.4
  • 3
    • 81255143119 scopus 로고    scopus 로고
    • Protective effect of Chrysin on carbon tetrachloride (CCl4)-induced tissue injury in male Wistar rats
    • K.V. Anand, R. Anandhi, M. Pakkiyaraj, and P. Geraldine Protective effect of Chrysin on carbon tetrachloride (CCl4)-induced tissue injury in male Wistar rats Toxicol Ind Health 27 2011 923 933
    • (2011) Toxicol Ind Health , vol.27 , pp. 923-933
    • Anand, K.V.1    Anandhi, R.2    Pakkiyaraj, M.3    Geraldine, P.4
  • 4
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principles of protein-dye binding
    • M.M. Bradford A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principles of protein-dye binding Anal Biochem 72 1976 248 254
    • (1976) Anal Biochem , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 5
    • 0036011232 scopus 로고    scopus 로고
    • Beneficial effects of Chrysin and benzoflavone on virility in 2-year-old male rats
    • K. Dhawan, S. Kumar, and A. Sharma Beneficial effects of Chrysin and benzoflavone on virility in 2-year-old male rats J Med Food 5 2002 43 48
    • (2002) J Med Food , vol.5 , pp. 43-48
    • Dhawan, K.1    Kumar, S.2    Sharma, A.3
  • 6
    • 0037240518 scopus 로고    scopus 로고
    • The neurobiology of memory changes in normal aging
    • C.A. Erickson, and C.A. Barnes The neurobiology of memory changes in normal aging Exp Gerontol 38 2003 61 69
    • (2003) Exp Gerontol , vol.38 , pp. 61-69
    • Erickson, C.A.1    Barnes, C.A.2
  • 7
    • 0000154206 scopus 로고
    • The calorimetric determination of phosphorus
    • C.H. Fiske, and Y.J. Subbarow The calorimetric determination of phosphorus Biol Chem 66 1925 375 381
    • (1925) Biol Chem , vol.66 , pp. 375-381
    • Fiske, C.H.1    Subbarow, Y.J.2
  • 8
    • 84904350824 scopus 로고    scopus 로고
    • Voluntary wheel running, but not a diet containing (-)-epigallocatechin-3-gallate and β-alanine, improves learning, memory and hippocampal neurogenesis in aged mice
    • T.E. Gibbons, B.D. Pence, G. Petr, J.M. Ossyra, H.C. Mach, and T.K. Bhattacharya Voluntary wheel running, but not a diet containing (-)-epigallocatechin-3-gallate and β-alanine, improves learning, memory and hippocampal neurogenesis in aged mice Behav Brain Res 272 2014 131 140
    • (2014) Behav Brain Res , vol.272 , pp. 131-140
    • Gibbons, T.E.1    Pence, B.D.2    Petr, G.3    Ossyra, J.M.4    Mach, H.C.5    Bhattacharya, T.K.6
  • 9
    • 71349087186 scopus 로고    scopus 로고
    • Origin and evolution of the free radical theory of aging: A brief personal history, 1954-2009
    • D. Harman Origin and evolution of the free radical theory of aging: a brief personal history, 1954-2009 Biogerontology 10 2009 773 781
    • (2009) Biogerontology , vol.10 , pp. 773-781
    • Harman, D.1
  • 10
    • 84862832586 scopus 로고    scopus 로고
    • Chrysin improves cognitive deficits and brain damage induced by chronic cerebral hypoperfusion in rats
    • X.L. He, Y.H. Wang, M.G. Bi, and G.H. Du Chrysin improves cognitive deficits and brain damage induced by chronic cerebral hypoperfusion in rats Eur J Pharmacol 680 2012 41 48
    • (2012) Eur J Pharmacol , vol.680 , pp. 41-48
    • He, X.L.1    Wang, Y.H.2    Bi, M.G.3    Du, G.H.4
  • 11
    • 33846246768 scopus 로고    scopus 로고
    • Protective effect of an extract of the oyster mushroom, Pleurotus ostreatus, on antioxidants of major organs of aged rats
    • T. Jayakumar, P.A. Thomas, and P. Geraldine Protective effect of an extract of the oyster mushroom, Pleurotus ostreatus, on antioxidants of major organs of aged rats Exp Gerontol 42 2007 183 191
    • (2007) Exp Gerontol , vol.42 , pp. 183-191
    • Jayakumar, T.1    Thomas, P.A.2    Geraldine, P.3
  • 13
    • 84904605998 scopus 로고    scopus 로고
    • Evaluation of the neuroprotective effect of Chrysin via modulation of endogenous biomarkers in a rat model of spinal cord injury
    • A.D. Kandhare, V. Shivakumar, A. Rajmane, P. Ghosh, and S.L. Bodhankar Evaluation of the neuroprotective effect of Chrysin via modulation of endogenous biomarkers in a rat model of spinal cord injury J Nat Med 68 2014 586 603
    • (2014) J Nat Med , vol.68 , pp. 586-603
    • Kandhare, A.D.1    Shivakumar, V.2    Rajmane, A.3    Ghosh, P.4    Bodhankar, S.L.5
  • 14
    • 0035937653 scopus 로고    scopus 로고
    • Acetyl-L-cranitine enhances Na +, K + ATPase, glutathione-s-transferase and multiple unit activity and reduces lipid peroxidation and lipofuscin concentration in aged rat brain regions
    • J. Kaur, D. Sharma, and R. Singh Acetyl-L-cranitine enhances Na +, K + ATPase, glutathione-s-transferase and multiple unit activity and reduces lipid peroxidation and lipofuscin concentration in aged rat brain regions Neurosci Lett 301 2001 1 4
    • (2001) Neurosci Lett , vol.301 , pp. 1-4
    • Kaur, J.1    Sharma, D.2    Singh, R.3
  • 15
    • 79952695020 scopus 로고    scopus 로고
    • Protective effect of caffeine and a selective A2A receptor antagonist on impairment of memory and oxidative stress of aged rats
    • M.R. Leite, E.A. Wilhelm, C.R. Jesse, R. Brandão, and C.W. Nogueira Protective effect of caffeine and a selective A2A receptor antagonist on impairment of memory and oxidative stress of aged rats Exp Gerontol 46 2011 309 315
    • (2011) Exp Gerontol , vol.46 , pp. 309-315
    • Leite, M.R.1    Wilhelm, E.A.2    Jesse, C.R.3    Brandão, R.4    Nogueira, C.W.5
  • 16
    • 84907592869 scopus 로고    scopus 로고
    • Chrysin ameliorates diabetes-associated cognitive deficits in Wistar rats
    • R. Li, A. Zang, L. Zhang, H. Zhang, L. Zhao, and Z. Qi Chrysin ameliorates diabetes-associated cognitive deficits in Wistar rats Neurol Sci 35 2014 1527 1532
    • (2014) Neurol Sci , vol.35 , pp. 1527-1532
    • Li, R.1    Zang, A.2    Zhang, L.3    Zhang, H.4    Zhao, L.5    Qi, Z.6
  • 17
    • 0038491473 scopus 로고    scopus 로고
    • Reversal of age-related learning deficits and brain oxidative stress in mice with superoxide dismutase/catalase mimetics
    • R. Liu, I.Y. Liu, X. Bi, R.F. Thompson, S.R. Doctrow, and B. Malfroy Reversal of age-related learning deficits and brain oxidative stress in mice with superoxide dismutase/catalase mimetics Proc Natl Acad Sci U S A 100 2003 8526 8531
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 8526-8531
    • Liu, R.1    Liu, I.Y.2    Bi, X.3    Thompson, R.F.4    Doctrow, S.R.5    Malfroy, B.6
  • 18
    • 9644294527 scopus 로고    scopus 로고
    • MankhetkornS. Spectrofluorometric determination of intracellular levels of reactiveoxygen species in drug-sensitive and drug-resistant cancer cells usingthe 2,7-dichlorofluorescein diacetate assay
    • C. Loetchutinat, S. Kothan, S. Dechsupa, J. Meesungnoen, and J. Jay-Gerin MankhetkornS. Spectrofluorometric determination of intracellular levels of reactiveoxygen species in drug-sensitive and drug-resistant cancer cells usingthe 2,7-dichlorofluorescein diacetate assay Radiat Phys Chem 72 2005 323 331
    • (2005) Radiat Phys Chem , vol.72 , pp. 323-331
    • Loetchutinat, C.1    Kothan, S.2    Dechsupa, S.3    Meesungnoen, J.4    Jay-Gerin, J.5
  • 19
    • 84876672005 scopus 로고    scopus 로고
    • Decreased activity of Ca(++)-ATPase and Na(+)/K(+) ATPase during aging in humans
    • P.K. Maurya, and S. Prakash Decreased activity of Ca(++)-ATPase and Na(+)/K(+) ATPase during aging in humans Appl Biochem Biotechnol 170 2013 131 137
    • (2013) Appl Biochem Biotechnol , vol.170 , pp. 131-137
    • Maurya, P.K.1    Prakash, S.2
  • 20
    • 13844271390 scopus 로고    scopus 로고
    • Dietary polyphenols protect dopamine neurons from oxidative insults and apoptosis: Investigations in primary rat mesencephalic cultures
    • L.D. Mercer, B.L. Kelly, M.K. Horne, and P.M. Beart Dietary polyphenols protect dopamine neurons from oxidative insults and apoptosis: investigations in primary rat mesencephalic cultures Biochem Pharmacol 69 2005 339 345
    • (2005) Biochem Pharmacol , vol.69 , pp. 339-345
    • Mercer, L.D.1    Kelly, B.L.2    Horne, M.K.3    Beart, P.M.4
  • 21
    • 0015523099 scopus 로고
    • The role of superoxide anion in the autoxidation of epinephrine and simple assay for superoxide dismutase
    • H.P. Misra, and I. Fridovich The role of superoxide anion in the autoxidation of epinephrine and simple assay for superoxide dismutase J Biol Chem 247 1972 3170 3175
    • (1972) J Biol Chem , vol.247 , pp. 3170-3175
    • Misra, H.P.1    Fridovich, I.2
  • 22
    • 0033600503 scopus 로고    scopus 로고
    • Deprivation of endogenous brain-derived neurotrophic factor results in impairment of spatial learning and memory in adult rats
    • J.S. Mu, W.P. Li, Z.B. Yao, and X.F. Zhou Deprivation of endogenous brain-derived neurotrophic factor results in impairment of spatial learning and memory in adult rats Brain Res 835 1999 259 265
    • (1999) Brain Res , vol.835 , pp. 259-265
    • Mu, J.S.1    Li, W.P.2    Yao, Z.B.3    Zhou, X.F.4
  • 23
    • 84871408179 scopus 로고    scopus 로고
    • Neurotrophin regulation of neural circuit development and function
    • H. Park, and M.M. Poo Neurotrophin regulation of neural circuit development and function Nat Rev Neurosci 14 2013 7 23
    • (2013) Nat Rev Neurosci , vol.14 , pp. 7-23
    • Park, H.1    Poo, M.M.2
  • 24
    • 0035234670 scopus 로고    scopus 로고
    • Neurotrophins as synaptic modulators
    • M.M. Poo Neurotrophins as synaptic modulators Nat Rev Neurosci 2 2001 24 32
    • (2001) Nat Rev Neurosci , vol.2 , pp. 24-32
    • Poo, M.M.1
  • 25
    • 33846433513 scopus 로고    scopus 로고
    • Differential susceptibility following beta-amyloid peptide-(1-40) administration in C57BL/6 and Swiss albino mice: Evidence for a dissociation between cognitive deficits and the glutathione system response
    • R.D. Prediger, J.L. Franco, P. Pandolfo, R. Medeiros, F.S. Duarte, G. Di Giunta, C.P. Figueiredo, M. Farina, J.B. Calixto, R.N. Takahashi, and A.L. Dafre Differential susceptibility following beta-amyloid peptide-(1-40) administration in C57BL/6 and Swiss albino mice: Evidence for a dissociation between cognitive deficits and the glutathione system response Behav Brain Res 177 2 2007 205 213
    • (2007) Behav Brain Res , vol.177 , Issue.2 , pp. 205-213
    • Prediger, R.D.1    Franco, J.L.2    Pandolfo, P.3    Medeiros, R.4    Duarte, F.S.5    Di Giunta, G.6    Figueiredo, C.P.7    Farina, M.8    Calixto, J.B.9    Takahashi, R.N.10    Dafre, A.L.11
  • 26
    • 84867765388 scopus 로고    scopus 로고
    • Panax ginseng reduces oxidative stress and restores antioxidant capacity in aged rats
    • T. Ramesh, S.W. Kim, S.Y. Hwang, S.H. Sohn, S.K. Yoo, and S.K. Kim Panax ginseng reduces oxidative stress and restores antioxidant capacity in aged rats Nutr Res 32 2012 718 726
    • (2012) Nutr Res , vol.32 , pp. 718-726
    • Ramesh, T.1    Kim, S.W.2    Hwang, S.Y.3    Sohn, S.H.4    Yoo, S.K.5    Kim, S.K.6
  • 27
    • 0037936789 scopus 로고    scopus 로고
    • Impact of aging on hippocampal function: Plasticity, network dynamics, and cognition
    • E.S. Rosenzweig, and C.A. Barnes Impact of aging on hippocampal function: plasticity, network dynamics, and cognition Prog Neurobiol 69 2003 143 179
    • (2003) Prog Neurobiol , vol.69 , pp. 143-179
    • Rosenzweig, E.S.1    Barnes, C.A.2
  • 28
    • 84866378617 scopus 로고    scopus 로고
    • Chronic caffeine prevents changes in inhibitory avoidance memory and hippocampal BDNF immunocontent in middle-aged rats
    • C. Sallaberry, F. Nunes, M.S. Costa, G.T. Fioreze, A.P. Ardais, and P.H. Botton Chronic caffeine prevents changes in inhibitory avoidance memory and hippocampal BDNF immunocontent in middle-aged rats Neuropharmacology 64 2013 153 159
    • (2013) Neuropharmacology , vol.64 , pp. 153-159
    • Sallaberry, C.1    Nunes, F.2    Costa, M.S.3    Fioreze, G.T.4    Ardais, A.P.5    Botton, P.H.6
  • 29
    • 85047682479 scopus 로고    scopus 로고
    • Hepatoprotective effect of Chrysin on prooxidant-antioxidant status during ethanol-induced toxicity in female albino rats
    • J. Sathiavelu, G.J. Senapathy, R. Devaraj, and N. Namasivayam Hepatoprotective effect of Chrysin on prooxidant-antioxidant status during ethanol-induced toxicity in female albino rats J Pharm Pharmacol 61 2009 809 817
    • (2009) J Pharm Pharmacol , vol.61 , pp. 809-817
    • Sathiavelu, J.1    Senapathy, G.J.2    Devaraj, R.3    Namasivayam, N.4
  • 31
    • 53949111613 scopus 로고    scopus 로고
    • New insights into brain BDNF function in normal aging and Alzheimer disease
    • L. Tapia-Arancibia, E. Aliaga, M. Silhol, and S. Arancibia New insights into brain BDNF function in normal aging and Alzheimer disease Brain Res Rev 59 2008 201 220
    • (2008) Brain Res Rev , vol.59 , pp. 201-220
    • Tapia-Arancibia, L.1    Aliaga, E.2    Silhol, M.3    Arancibia, S.4
  • 32
    • 84890328542 scopus 로고    scopus 로고
    • Combination of N-acetylcysteine, α-lipoic acid and α-tocopherol substantially prevents the brain synaptosomal alterations and memory and learning deficits of aged rats
    • I.G. Thakurta, P. Banerjee, M.B. Bagh, A. Ghosh, A. Sahoo, and S. Chattopadhyay Combination of N-acetylcysteine, α-lipoic acid and α-tocopherol substantially prevents the brain synaptosomal alterations and memory and learning deficits of aged rats Exp Gerontol 50 2014 19 25
    • (2014) Exp Gerontol , vol.50 , pp. 19-25
    • Thakurta, I.G.1    Banerjee, P.2    Bagh, M.B.3    Ghosh, A.4    Sahoo, A.5    Chattopadhyay, S.6
  • 33
    • 0000650706 scopus 로고
    • The open-field test: A critical review
    • R.N. Walsh, and R.A. Cummins The open-field test: a critical review Psychol Bull 415 1976 482 504
    • (1976) Psychol Bull , vol.415 , pp. 482-504
    • Walsh, R.N.1    Cummins, R.A.2
  • 34
    • 0019740344 scopus 로고
    • Glutathione peroxidase
    • A. Wendel Glutathione peroxidase Methods Enzymol 177 1981 325 333
    • (1981) Methods Enzymol , vol.177 , pp. 325-333
    • Wendel, A.1
  • 35
    • 84884286108 scopus 로고    scopus 로고
    • Anti-tumor activity evaluation of novel Chrysin-organogermanium(IV) complex in MCF-7 cells
    • F. Yang, H. Jin, J. Pi, J.H. Jiang, L. Liu, and H.H. Bai Anti-tumor activity evaluation of novel Chrysin-organogermanium(IV) complex in MCF-7 cells Bioorg Med Chem Lett 23 2013 5544 5551
    • (2013) Bioorg Med Chem Lett , vol.23 , pp. 5544-5551
    • Yang, F.1    Jin, H.2    Pi, J.3    Jiang, J.H.4    Liu, L.5    Bai, H.H.6
  • 36
    • 0842289239 scopus 로고    scopus 로고
    • Spatial learning transiently disturbed by intraventricular administration of ouabain
    • H. Zhan, T. Tada, F. Nakazato, Y. Tanaka, and K. Hongo Spatial learning transiently disturbed by intraventricular administration of ouabain Neurol Res 26 2004 35 40
    • (2004) Neurol Res , vol.26 , pp. 35-40
    • Zhan, H.1    Tada, T.2    Nakazato, F.3    Tanaka, Y.4    Hongo, K.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.