메뉴 건너뛰기




Volumn 125, Issue 5, 2015, Pages 679-689

New signaling pathways govern the host response to C. albicans infection in various niches

Author keywords

[No Author keywords available]

Indexed keywords

FUNGAL RNA; NEURAL PRECURSOR CELL EXPRESSED DEVELOPMENTALLY DOWN REGULATED PROTEIN 9; PLATELET DERIVED GROWTH FACTOR BB; PROTEIN; SMALL INTERFERING RNA; TRANSCRIPTOME; UNCLASSIFIED DRUG; BECAPLERMIN; NEDD9 PROTEIN, HUMAN; PHOSPHOPROTEIN; PLATELET DERIVED GROWTH FACTOR B; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

EID: 84929659360     PISSN: 10889051     EISSN: 15495469     Source Type: Journal    
DOI: 10.1101/gr.187427.114     Document Type: Article
Times cited : (75)

References (65)
  • 1
    • 11344258625 scopus 로고    scopus 로고
    • Candidemia in patients with diabetes mellitus: Epidemiology and predictors of mortality
    • Bader MS, Lai SM, Kumar V, Hinthorn D. 2004. Candidemia in patients with diabetes mellitus: epidemiology and predictors of mortality. Scand J Infect Dis 36: 860-864.
    • (2004) Scand J Infect Dis , vol.36 , pp. 860-864
    • Bader, M.S.1    Lai, S.M.2    Kumar, V.3    Hinthorn, D.4
  • 3
    • 0028355888 scopus 로고
    • PDGF-BB modulates endothelial proliferation and angiogenesis in vitro via PDGF -receptors
    • Battegay EJ, Rupp J, Iruela-Arispe L, Sage EH, Pech M. 1994. PDGF-BB modulates endothelial proliferation and angiogenesis in vitro via PDGF -receptors. J Cell Biol 125: 917-928.
    • (1994) J Cell Biol , vol.125 , pp. 917-928
    • Battegay, E.J.1    Rupp, J.2    Iruela-Arispe, L.3    Sage, E.H.4    Pech, M.5
  • 4
    • 9644262800 scopus 로고    scopus 로고
    • Transcriptional profiling in Candida albicans reveals new adaptive responses to extracellular pH and functions for Rim101p
    • Bensen ES, Martin SJ, Li M, Berman J, Davis DA. 2004. Transcriptional profiling in Candida albicans reveals new adaptive responses to extracellular pH and functions for Rim101p. Mol Microbiol 54: 1335-1351.
    • (2004) Mol Microbiol , vol.54 , pp. 1335-1351
    • Bensen, E.S.1    Martin, S.J.2    Li, M.3    Berman, J.4    Davis, D.A.5
  • 5
    • 77951777930 scopus 로고    scopus 로고
    • A comparison of massively parallel nucleotide sequencing with oligonucleotide microarrays for global transcription profiling
    • Bradford JR, Hey Y, Yates T, Li Y, Pepper SD, Miller CJ. 2010. A comparison of massively parallel nucleotide sequencing with oligonucleotide microarrays for global transcription profiling. BMC Genomics 11: 282.
    • (2010) BMC Genomics , vol.11 , pp. 282
    • Bradford, J.R.1    Hey, Y.2    Yates, T.3    Li, Y.4    Pepper, S.D.5    Miller, C.J.6
  • 6
    • 78649240033 scopus 로고    scopus 로고
    • Comprehensive annotation of the transcriptome of the human fungal pathogen Candida albicans using RNA-seq
    • Bruno VM, Wang Z, Marjani SL, Euskirchen GM, Martin J, Sherlock G, Snyder M. 2010. Comprehensive annotation of the transcriptome of the human fungal pathogen Candida albicans using RNA-seq. Genome Res 20: 1451-1458.
    • (2010) Genome Res , vol.20 , pp. 1451-1458
    • Bruno, V.M.1    Wang, Z.2    Marjani, S.L.3    Euskirchen, G.M.4    Martin, J.5    Sherlock, G.6    Snyder, M.7
  • 8
    • 0036681758 scopus 로고    scopus 로고
    • Candida albicans stimulates local expression of leukocyte adhesion molecules and cytokines in vivo
    • Cannom RR, FrenchSW, Johnston D, Edwards JE Jr, Filler SG. 2002. Candida albicans stimulates local expression of leukocyte adhesion molecules and cytokines in vivo. J Infect Dis 186: 389-396.
    • (2002) J Infect Dis , vol.186 , pp. 389-396
    • Cannom, R.R.1    French, S.W.2    Johnston, D.3    Edwards, J.E.4    Filler, S.G.5
  • 11
    • 84902087291 scopus 로고    scopus 로고
    • PDGF receptor signaling networks in normal and cancer cells
    • Demoulin JB, Essaghir A. 2014. PDGF receptor signaling networks in normal and cancer cells. Cytokine Growth Factor Rev 25: 273-283.
    • (2014) Cytokine Growth Factor Rev , vol.25 , pp. 273-283
    • Demoulin, J.B.1    Essaghir, A.2
  • 12
    • 0033979731 scopus 로고    scopus 로고
    • Human keratinocytes that express hTERT and also bypass a p16INK4a-enforced mechanism that limits life span become immortal yet retain normal growth and differentiation characteristics
    • Dickson MA, Hahn WC, Ino Y, Ronfard V, Wu JY, Weinberg RA, Louis DN, Li FP, Rheinwald JG. 2000. Human keratinocytes that express hTERT and also bypass a p16INK4a-enforced mechanism that limits life span become immortal yet retain normal growth and differentiation characteristics. Mol Cell Biol 20: 1436-1447.
    • (2000) Mol Cell Biol , vol.20 , pp. 1436-1447
    • Dickson, M.A.1    Hahn, W.C.2    Ino, Y.3    Ronfard, V.4    Wu, J.Y.5    Weinberg, R.A.6    Louis, D.N.7    Li, F.P.8    Rheinwald, J.G.9
  • 13
    • 42949086499 scopus 로고    scopus 로고
    • RNA interference screen identifies Abl kinase and PDGFR signaling in Chlamydia trachomatis entry
    • Elwell CA, Ceesay A, Kim JH, Kalman D, Engel JN. 2008. RNA interference screen identifies Abl kinase and PDGFR signaling in Chlamydia trachomatis entry. PLoS Pathog 4: e1000021.
    • (2008) PLoS Pathog , vol.4 , pp. e1000021
    • Elwell, C.A.1    Ceesay, A.2    Kim, J.H.3    Kalman, D.4    Engel, J.N.5
  • 14
    • 0028916787 scopus 로고
    • Penetration and damage of endothelial cells by Candida albicans
    • Filler SG, Swerdloff JN, Hobbs C, Luckett PM. 1995. Penetration and damage of endothelial cells by Candida albicans. Infect Immun 63: 976-983.
    • (1995) Infect Immun , vol.63 , pp. 976-983
    • Filler, S.G.1    Swerdloff, J.N.2    Hobbs, C.3    Luckett, P.M.4
  • 16
    • 3142726042 scopus 로고    scopus 로고
    • Incidence of bloodstream infections due to Candida species and in vitro susceptibilities of isolates collected from 1998 to 2000 in a population-based active surveillance program
    • Hajjeh RA, Sofair AN, Harrison LH, Lyon GM, Arthington-Skaggs BA, Mirza SA, Phelan M, Morgan J, Lee-YangW, Ciblak MA, et al. 2004. Incidence of bloodstream infections due to Candida species and in vitro susceptibilities of isolates collected from 1998 to 2000 in a population-based active surveillance program. J Clin Microbiol 42: 1519-1527.
    • (2004) J Clin Microbiol , vol.42 , pp. 1519-1527
    • Hajjeh, R.A.1    Sofair, A.N.2    Harrison, L.H.3    Lyon, G.M.4    Arthington-Skaggs, B.A.5    Mirza, S.A.6    Phelan, M.7    Morgan, J.8    Lee-Yang, W.9    Ciblak, M.A.10
  • 18
    • 85027945875 scopus 로고    scopus 로고
    • Identification by DNA microarray of genes involved in Candida albicans-treated gingival epithelial cells
    • Ikuta T, Bhawal UK, Tsushima K, Aoki A, Kuboyama N, Abiko Y. 2012. Identification by DNA microarray of genes involved in Candida albicans-treated gingival epithelial cells. J Oral Pathol Med 41: 769-778.
    • (2012) J Oral Pathol Med , vol.41 , pp. 769-778
    • Ikuta, T.1    Bhawal, U.K.2    Tsushima, K.3    Aoki, A.4    Kuboyama, N.5    Abiko, Y.6
  • 19
    • 84876996918 scopus 로고    scopus 로고
    • TopHat2: Accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions
    • Kim D, Pertea G, Trapnell C, Pimentel H, Kelley R, Salzberg SL. 2013. TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions. Genome Biol 14: R36.
    • (2013) Genome Biol , vol.14 , pp. R36
    • Kim, D.1    Pertea, G.2    Trapnell, C.3    Pimentel, H.4    Kelley, R.5    Salzberg, S.L.6
  • 20
    • 33744493394 scopus 로고    scopus 로고
    • Candida resistance and its clinical relevance
    • Klepser ME. 2006. Candida resistance and its clinical relevance. Pharmacotherapy 26: 68S-75S.
    • (2006) Pharmacotherapy , vol.26 , pp. 68S-75S
    • Klepser, M.E.1
  • 21
    • 0016283728 scopus 로고
    • Platelets as a source of fibroblast growth-promoting activity
    • Kohler N, Lipton A. 1974. Platelets as a source of fibroblast growth-promoting activity. Exp Cell Res 87: 297-301.
    • (1974) Exp Cell Res , vol.87 , pp. 297-301
    • Kohler, N.1    Lipton, A.2
  • 22
    • 0342546626 scopus 로고    scopus 로고
    • Phosphorylation site-specific inhibition of platelet-derived growth factor -receptor autophosphorylation by the receptor blocking tyrphostin AG1296
    • Kovalenko M, Rönnstrand L, Heldin CH, Loubtchenkov M, Gazit A, Levitzki A, Böhmer FD. 1997. Phosphorylation site-specific inhibition of platelet-derived growth factor -receptor autophosphorylation by the receptor blocking tyrphostin AG1296. Biochemistry 36: 6260-6269.
    • (1997) Biochemistry , vol.36 , pp. 6260-6269
    • Kovalenko, M.1    Rönnstrand, L.2    Heldin, C.H.3    Loubtchenkov, M.4    Gazit, A.5    Levitzki, A.6    Böhmer, F.D.7
  • 24
    • 79960248741 scopus 로고    scopus 로고
    • Transcriptome profiling of endothelial cells during infections with high and low densities of C albicans cells
    • Lim CS, Rosli R, Seow HF, Chong PP. 2011. Transcriptome profiling of endothelial cells during infections with high and low densities of C. albicans cells. Int J Med Microbiol 301: 536-546.
    • (2011) Int J Med Microbiol , vol.301 , pp. 536-546
    • Lim, C.S.1    Rosli, R.2    Seow, H.F.3    Chong, P.P.4
  • 28
    • 79957665988 scopus 로고    scopus 로고
    • Microarrays, deep sequencing and the true measure of the transcriptome
    • Malone JH, Oliver B. 2011. Microarrays, deep sequencing and the true measure of the transcriptome. BMC Biol 9: 34.
    • (2011) BMC Biol , vol.9 , pp. 34
    • Malone, J.H.1    Oliver, B.2
  • 29
    • 50649089207 scopus 로고    scopus 로고
    • RNA-seq: An assessment of technical reproducibility and comparison with gene expression arrays
    • Marioni JC, Mason CE, Mane SM, Stephens M, Gilad Y. 2008. RNA-seq: an assessment of technical reproducibility and comparison with gene expression arrays. Genome Res 18: 1509-1517.
    • (2008) Genome Res , vol.18 , pp. 1509-1517
    • Marioni, J.C.1    Mason, C.E.2    Mane, S.M.3    Stephens, M.4    Gilad, Y.5
  • 31
    • 0037019285 scopus 로고    scopus 로고
    • Potent and selective inhibitors of platelet-derived growth factor receptor phosphorylation. 1. Synthesis, structure-activity relationship, and biological effects of a new class of quinazoline derivatives
    • Matsuno K, Ichimura M, Nakajima T, Tahara K, Fujiwara S, Kase H, Ushiki J, Giese NA, Pandey A, Scarborough RM, et al. 2002. Potent and selective inhibitors of platelet-derived growth factor receptor phosphorylation. 1. Synthesis, structure-activity relationship, and biological effects of a new class of quinazoline derivatives. J Med Chem 45: 3057-3066.
    • (2002) J Med Chem , vol.45 , pp. 3057-3066
    • Matsuno, K.1    Ichimura, M.2    Nakajima, T.3    Tahara, K.4    Fujiwara, S.5    Kase, H.6    Ushiki, J.7    Giese, N.A.8    Pandey, A.9    Scarborough, R.M.10
  • 33
    • 84900536186 scopus 로고    scopus 로고
    • Protection against epithelial damage during Candida albicans infection is mediated by PI3K/Akt andmammalian target of rapamycin signaling
    • Moyes DL, Shen C, Murciano C, Runglall M, Richardson JP, Arno M, Aldecoa-Otalora E, Naglik JR. 2014. Protection against epithelial damage during Candida albicans infection is mediated by PI3K/Akt andmammalian target of rapamycin signaling. J Infect Dis 209: 1816-1826.
    • (2014) J Infect Dis , vol.209 , pp. 1816-1826
    • Moyes, D.L.1    Shen, C.2    Murciano, C.3    Runglall, M.4    Richardson, J.P.5    Arno, M.6    Aldecoa-Otalora, E.7    Naglik, J.R.8
  • 34
    • 40049105940 scopus 로고    scopus 로고
    • Candida albicans triggers activation of distinct signaling pathways to establish a proinflammatory gene expression program in primary human endothelial cells
    • Müller V, Viemann D, Schmidt M, Endres N, Ludwig S, Leverkus M, Roth J, Goebeler M. 2007. Candida albicans triggers activation of distinct signaling pathways to establish a proinflammatory gene expression program in primary human endothelial cells. J Immunol 179: 8435-8445.
    • (2007) J Immunol , vol.179 , pp. 8435-8445
    • Müller, V.1    Viemann, D.2    Schmidt, M.3    Endres, N.4    Ludwig, S.5    Leverkus, M.6    Roth, J.7    Goebeler, M.8
  • 36
    • 4344637673 scopus 로고    scopus 로고
    • Candida albicans genome sequence: A platform for genomics in the absence of genetics
    • Odds FC, Brown AJ, Gow NA. 2004. Candida albicans genome sequence: a platform for genomics in the absence of genetics. Genome Biol 5: 230.
    • (2004) Genome Biol , vol.5 , pp. 230
    • Odds, F.C.1    Brown, A.J.2    Gow, N.A.3
  • 37
    • 0033956316 scopus 로고    scopus 로고
    • Mechanisms of the proinflammatory response of endothelial cells to Candida albicans infection
    • Orozco AS, Zhou X, Filler SG. 2000. Mechanisms of the proinflammatory response of endothelial cells to Candida albicans infection. Infect Immun 68: 1134-1141.
    • (2000) Infect Immun , vol.68 , pp. 1134-1141
    • Orozco, A.S.1    Zhou, X.2    Filler, S.G.3
  • 38
    • 15944381558 scopus 로고    scopus 로고
    • Role of the fungal Ras-protein kinase A pathway in governing epithelial cell interactions during oropharyngeal candidiasis
    • Park H, Myers CL, Sheppard DC, Phan QT, Sanchez AA, Edwards JE, Filler SG. 2005. Role of the fungal Ras-protein kinase A pathway in governing epithelial cell interactions during oropharyngeal candidiasis. Cell Microbiol 7: 499-510.
    • (2005) Cell Microbiol , vol.7 , pp. 499-510
    • Park, H.1    Myers, C.L.2    Sheppard, D.C.3    Phan, Q.T.4    Sanchez, A.A.5    Edwards, J.E.6    Filler, S.G.7
  • 40
    • 0034115442 scopus 로고    scopus 로고
    • Role of hyphal formation in interactions of Candida albicans with endothelial cells
    • Phan QT, Belanger PH, Filler SG. 2000. Role of hyphal formation in interactions of Candida albicans with endothelial cells. Infect Immun 68: 3485-3490.
    • (2000) Infect Immun , vol.68 , pp. 3485-3490
    • Phan, Q.T.1    Belanger, P.H.2    Filler, S.G.3
  • 41
  • 43
    • 0032788359 scopus 로고    scopus 로고
    • National epidemiology of mycoses survey (NEMIS): Variations in rates of bloodstream infections due to Candida species in seven surgical intensive care units and six neonatal intensive care units
    • Rangel-Frausto MS, Wiblin T, Blumberg HM, Saiman L, Patterson J, Rinaldi M, Pfaller M, Edwards JE Jr, Jarvis W, Dawson J, et al. 1999. National epidemiology of mycoses survey (NEMIS): variations in rates of bloodstream infections due to Candida species in seven surgical intensive care units and six neonatal intensive care units. Clin Infect Dis 29: 253-258.
    • (1999) Clin Infect Dis , vol.29 , pp. 253-258
    • Rangel-Frausto, M.S.1    Wiblin, T.2    Blumberg, H.M.3    Saiman, L.4    Patterson, J.5    Rinaldi, M.6    Pfaller, M.7    Edwards, J.E.8    Jarvis, W.9    Dawson, J.10
  • 47
    • 0030695988 scopus 로고    scopus 로고
    • Prevalence, density, and manifestations of oral Candida albicans in patients with Sjögren's syndrome
    • Rhodus NL, Bloomquist C, Liljemark W, Bereuter J. 1997. Prevalence, density, and manifestations of oral Candida albicans in patients with Sjögren's syndrome. J Otolaryngol 26: 300-305.
    • (1997) J Otolaryngol , vol.26 , pp. 300-305
    • Rhodus, N.L.1    Bloomquist, C.2    Liljemark, W.3    Bereuter, J.4
  • 48
    • 1842280753 scopus 로고
    • A platelet-dependent serum factor that stimulates the proliferation of arterial smooth muscle cells in vitro
    • Ross R, Glomset J, Kariya B, Harker L. 1974. A platelet-dependent serum factor that stimulates the proliferation of arterial smooth muscle cells in vitro. Proc Natl Acad Sci 71: 1207-1210.
    • (1974) Proc Natl Acad Sci , vol.71 , pp. 1207-1210
    • Ross, R.1    Glomset, J.2    Kariya, B.3    Harker, L.4
  • 49
    • 0346250987 scopus 로고    scopus 로고
    • Relationship between Candida albicans virulence during experimental hematogenously disseminated infection and endothelial cell damage in vitro
    • Sanchez AA, Johnston DA, Myers C, Edwards JE Jr, Mitchell AP, Filler SG. 2004. Relationship between Candida albicans virulence during experimental hematogenously disseminated infection and endothelial cell damage in vitro. Infect Immun 72: 598-601.
    • (2004) Infect Immun , vol.72 , pp. 598-601
    • Sanchez, A.A.1    Johnston, D.A.2    Myers, C.3    Edwards, J.E.4    Mitchell, A.P.5    Filler, S.G.6
  • 50
    • 33745289091 scopus 로고    scopus 로고
    • Gene transcription studies of Candida albicans following infection of HEp2 epithelial cells
    • Sandovsky-Losica H, Chauhan N, Calderone R, Segal E. 2006. Gene transcription studies of Candida albicans following infection of HEp2 epithelial cells. Med Mycol 44: 329-334.
    • (2006) Med Mycol , vol.44 , pp. 329-334
    • Sandovsky-Losica, H.1    Chauhan, N.2    Calderone, R.3    Segal, E.4
  • 51
    • 0027993041 scopus 로고
    • Epidemiology of oral candidiasis in HIV-infected patients: Colonization, infection, treatment, and emergence of fluconazole resistance
    • Sangeorzan JA, Bradley SF, He X, Zarins LT, Ridenour GL, Tiballi RN, Kauffman CA. 1994. Epidemiology of oral candidiasis in HIV-infected patients: colonization, infection, treatment, and emergence of fluconazole resistance. Am J Med 97: 339-346.
    • (1994) Am J Med , vol.97 , pp. 339-346
    • Sangeorzan, J.A.1    Bradley, S.F.2    He, X.3    Zarins, L.T.4    Ridenour, G.L.5    Tiballi, R.N.6    Kauffman, C.A.7
  • 53
    • 0023142875 scopus 로고
    • "Whiteopaque transition": A second high-frequency switching system in Candida albicans
    • Slutsky B, Staebell M, Anderson J, Risen L, Pfaller M, Soll DR. 1987. "Whiteopaque transition": a second high-frequency switching system in Candida albicans. J Bacteriol 169: 189-197.
    • (1987) J Bacteriol , vol.169 , pp. 189-197
    • Slutsky, B.1    Staebell, M.2    Anderson, J.3    Risen, L.4    Pfaller, M.5    Soll, D.R.6
  • 54
    • 0021816099 scopus 로고
    • Epidemiology and pathogenesis of recurrent vulvovaginal candidiasis
    • Sobel JD. 1985. Epidemiology and pathogenesis of recurrent vulvovaginal candidiasis. Am J Obstet Gynecol 152: 924-935.
    • (1985) Am J Obstet Gynecol , vol.152 , pp. 924-935
    • Sobel, J.D.1
  • 58
    • 23344449110 scopus 로고    scopus 로고
    • Invasive phenotype of Candida albicans affects the host proinflammatory response to infection
    • Villar CC, Kashleva H, Mitchell AP, Dongari-Bagtzoglou A. 2005. Invasive phenotype of Candida albicans affects the host proinflammatory response to infection. Infect Immun 73: 4588-4595.
    • (2005) Infect Immun , vol.73 , pp. 4588-4595
    • Villar, C.C.1    Kashleva, H.2    Mitchell, A.P.3    Dongari-Bagtzoglou, A.4
  • 59
    • 79952019135 scopus 로고    scopus 로고
    • From attachment to damage: Defined genes of Candida albicans mediate adhesion, invasion and damage during interaction with oral epithelial cells
    • Wachtler B, Wilson D, Haedicke K, Dalle F, Hube B. 2011. From attachment to damage: defined genes of Candida albicans mediate adhesion, invasion and damage during interaction with oral epithelial cells. PLoS One 6: e17046.
    • (2011) PLoS One , vol.6 , pp. e17046
    • Wachtler, B.1    Wilson, D.2    Haedicke, K.3    Dalle, F.4    Hube, B.5
  • 60
    • 57749195712 scopus 로고    scopus 로고
    • RNA-Seq: A revolutionary tool for transcriptomics
    • Wang Z, Gerstein M, Snyder M. 2009. RNA-Seq: a revolutionary tool for transcriptomics. Nat Rev Genet 10: 57-63.
    • (2009) Nat Rev Genet , vol.10 , pp. 57-63
    • Wang, Z.1    Gerstein, M.2    Snyder, M.3
  • 61
    • 0017280448 scopus 로고
    • A platelet factor stimulating human normal glial cells
    • Westermark B, Wasteson A. 1976. A platelet factor stimulating human normal glial cells. Exp Cell Res 98: 170-174.
    • (1976) Exp Cell Res , vol.98 , pp. 170-174
    • Westermark, B.1    Wasteson, A.2
  • 64
    • 35948998096 scopus 로고    scopus 로고
    • In vivo transcript profiling of Candida albicans identifies a gene essential for interepithelial dissemination
    • Zakikhany K, Naglik JR, Schmidt-Westhausen A, Holland G, Schaller M, Hube B. 2007. In vivo transcript profiling of Candida albicans identifies a gene essential for interepithelial dissemination. Cell Microbiol 9: 2938-2954.
    • (2007) Cell Microbiol , vol.9 , pp. 2938-2954
    • Zakikhany, K.1    Naglik, J.R.2    Schmidt-Westhausen, A.3    Holland, G.4    Schaller, M.5    Hube, B.6
  • 65
    • 84865545145 scopus 로고    scopus 로고
    • EGFR and HER2 receptor kinase signaling mediate epithelial cell invasion by Candida albicans during oropharyngeal infection
    • ZhuW, Phan QT, Boontheung P, Solis NV, Loo JA, Filler SG. 2012. EGFR and HER2 receptor kinase signaling mediate epithelial cell invasion by Candida albicans during oropharyngeal infection. Proc Natl Acad Sci 109: 14194-14199.
    • (2012) Proc Natl Acad Sci , vol.109 , pp. 14194-14199
    • Zhu, W.1    Phan, Q.T.2    Boontheung, P.3    Solis, N.V.4    Loo, J.A.5    Filler, S.G.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.