In vivo cartilage strain increases following medial meniscal tear and correlates with synovial fluid matrix metalloproteinase activity

Journal of Biomechanics

Volumn 48, Issue 8, 2015, Pages 1461-1468

  Carter, Teralyn E ^a   Taylor, Kevin A ^a   Spritzer, Charles E ^a   Utturkar, Gangadhar M ^a   Taylor, Dean C ^a   Moorman, Claude T ^a   Garrett, William E ^a   Guilak, Farshid ^a   McNulty, Amy L ^a   DeFrate, Louis E ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Aggrecan; Biomarker; Cartilage deformation; COMP; Mechanobiology; MRI

Indexed keywords

BIOMARKERS; CARTILAGE; DEFORMATION; HEALTH RISKS; MAGNETIC RESONANCE IMAGING; PHYSIOLOGICAL MODELS;

AGGRECAN; ARTICULAR CARTILAGES; COMP; CONTRALATERAL CONTROL; GLYCOSAMINOGLYCANS; MATRIX METALLOPROTEINASES; MECHANO-BIOLOGY; MEDIAL COMPARTMENT;

JOINTS (ANATOMY);

BIOLOGICAL MARKER; CARTILAGE OLIGOMERIC MATRIX PROTEIN; COLLAGEN TYPE 2; GLYCOSAMINOGLYCAN POLYSULFATE; MATRIX METALLOPROTEINASE; PROSTAGLANDIN E2;

ADULT; ARTICLE; ARTICULAR CARTILAGE; CARTILAGE; CATABOLISM; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; FLUOROSCOPY; HUMAN; IN VIVO STUDY; KNEE FLEXION ANGLE; KNEE MENISCUS RUPTURE; MALE; MUSCULOSKELETAL SYSTEM PARAMETERS; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; PROTEIN CLEAVAGE; SYNOVIAL FLUID; TISSUE METABOLISM; BIOMECHANICS; ENZYMOLOGY; JOINT CHARACTERISTICS AND FUNCTIONS; KNEE; KNEE INJURIES; KNEE MENISCUS; METABOLISM; MIDDLE AGED; PATHOLOGY; PATHOPHYSIOLOGY;

BIOMECHANICAL PHENOMENA; CARTILAGE OLIGOMERIC MATRIX PROTEIN; CARTILAGE, ARTICULAR; FEMALE; HUMANS; KNEE INJURIES; KNEE JOINT; MALE; MATRIX METALLOPROTEINASES; MENISCI, TIBIAL; MIDDLE AGED; RANGE OF MOTION, ARTICULAR; SYNOVIAL FLUID;

EID: 84929654792     PISSN: 00219290     EISSN: 18732380     Source Type: Journal    
DOI: 10.1016/j.jbiomech.2015.02.030     Document Type: Article

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