Restoration of the meniscus: Form and function

American Journal of Sports Medicine

Volumn 42, Issue 4, 2014, Pages 987-998

  Hutchinson, Ian D ^a   Moran, Cathal J ^b   Potter, Hollis G ^a   Warren, Russell F ^b   Rodeo, Scott A ^b  

^a HOSPITAL FOR SPECIAL SURGERY   (United States)

^b Sports Medicine and Shoulder Service   (United States)

Author keywords

knee meniscus; meniscal allograft transplantation; meniscal imaging; meniscal repair; meniscal scaffold; tissue engineering

Indexed keywords

COLLAGEN; POLYURETHAN;

ALLOGRAFT; ANIMAL; ARTICULAR CARTILAGE; BIOMECHANICS; HUMAN; INJURY; KNEE INJURY; KNEE MENISCUS; KNEE, MENISCUS; MENISCAL IMAGING; MENISCAL REPAIR; MENISCAL SCAFFOLD; MENISCAL TRANSPLANTATION; NUCLEAR MAGNETIC RESONANCE IMAGING; PROSTHESES AND ORTHOSES; REVIEW; TISSUE ENGINEERING; TRANSPLANTATION;

KNEE, MENISCUS; MENISCAL ALLOGRAFT TRANSPLANTATION; MENISCAL IMAGING; MENISCAL REPAIR; MENISCAL SCAFFOLD; TISSUE ENGINEERING;

ALLOGRAFTS; ANIMALS; BIOMECHANICAL PHENOMENA; CARTILAGE, ARTICULAR; COLLAGEN; HUMANS; KNEE INJURIES; MAGNETIC RESONANCE IMAGING; MENISCI, TIBIAL; POLYURETHANES; PROSTHESES AND IMPLANTS; TISSUE ENGINEERING;

EID: 84898930974     PISSN: 03635465     EISSN: 15523365     Source Type: Journal    
DOI: 10.1177/0363546513498503     Document Type: Article

References (111)

1. Abat F, Gelber PE, Erquicia JI, Tey M, Gonzalez-Lucena G, Monllau JC. Prospective comparative study between two different fixation techniques in meniscal allograft transplantation. Knee Surg Sports Traumatol Arthrosc. 2013 ; 21: 1516-1522
2. Alhalki MM, Howell SM, Hull ML. How three methods for fixing a medial meniscal autograft affect tibial contact mechanics. Am J Sports Med. 1999 ; 27 (3). 320-328 (Pubitemid 29239612)
3. Arnoczky SP. Building a meniscus. Biologic considerations. Clin Orthop Relat Res. 1999 ;: S244-253
4. Arnoczky SP, Warren RF. Microvasculature of the human meniscus. Am J Sports Med. 1982 ; 10 (2). 90-95 (Pubitemid 12126962)
5. Arnoczky SP, Warren RF. The microvasculature of the meniscus and its response to injury. An experimental study in the dog. Am J Sports Med. 1983 ; 11 (3). 131-141 (Pubitemid 13090213)
6. Arnoczky SP, Warren RF, Spivak JM. Meniscal repair using an exogenous fibrin clot. An experimental study in dogs. J Bone Joint Surg Am. 1988 ; 70 (8). 1209-1217
7. Bach BR, Dennis M, Balin J, Hayden J. Arthroscopic meniscal repair: analysis of treatment failures. J Knee Surg. 2005 ; 18 (4). 278-284
8. Baker BM, Shah RP, Silverstein AM, Esterhai JL, Burdick JA, Mauck RL. Sacrificial nanofibrous composites provide instruction without impediment and enable functional tissue formation. Proc Natl Acad Sci U S A. 2012 ; 109 (35). 14176-14181
9. Balint E, Gatt CJ, Dunn MG. Design and mechanical evaluation of a novel fiber-reinforced scaffold for meniscus replacement. J Biomed Mater Res A. 2012 ; 100 (1). 195-202
10. Ballyns JJ, Bonassar LJ. Dynamic compressive loading of image-guided tissue engineered meniscal constructs. J Biomech. 2011 ; 44 (3). 509-516
11. Baratz ME, Fu FH, Mengato R. Meniscal tears: the effect of meniscectomy and of repair on intraarticular contact areas and stress in the human knee. A preliminary report. Am J Sports Med. 1986 ; 14 (4). 270-275 (Pubitemid 16077330)
12. Barcia AM, Kozlowski EJ, Tokish JM. Return to sport after meniscal repair. Clin Sports Med. 2012 ; 31 (1). 155-166
13. Bedi A, Kelly NH, Baad M, et al. Dynamic contact mechanics of the medial meniscus as a function of radial tear, repair, and partial meniscectomy. J Bone Joint Surg Am. 2010 ; 92 (6). 1398-1408
14. Brophy RH, Lyman S, Chehab EL, Barnes RP, Rodeo SA, Warren RF. Predictive value of prior injury on career in professional American football is affected by player position. Am J Sports Med. 2009 ; 37 (4). 768-775
15. Bulgheroni P, Murena L, Ratti C, Bulgheroni E, Ronga M, Cherubino P. Follow-up of collagen meniscus implant patients: clinical, radiological, and magnetic resonance imaging results at 5 years. Knee. 2010 ; 17 (3). 224-229
16. Caplan AI, Correa D. The MSC: an injury drugstore. Cell Stem Cell. 2011 ; 9 (1). 11-15
17. Castillo TN, Pouliot MA, Kim HJ, Dragoo JL. Comparison of growth factor and platelet concentration from commercial platelet-rich plasma separation systems. Am J Sports Med. 2011 ; 39 (2). 266-271
18. Choi NH, Kim TH, Victoroff BN. Comparison of arthroscopic medial meniscal suture repair techniques: inside-out versus all-inside repair. Am J Sports Med. 2009 ; 37 (11). 2144-2150
19. Dallinga JM, Benjaminse A, Lemmink KA. Which screening tools can predict injury to the lower extremities in team sports?: a systematic review. Sports Med. 2012 ; 42 (9). 791-815
20. de Boer HH, Koudstaal J. Failed meniscus transplantation. A report of three cases. Clin Orthop Relat Res. 1994 (306). 155-162
21. Driscoll TP, Nerurkar NL, Jacobs NT, Elliott DM, Mauck RL. Fiber angle and aspect ratio influence the shear mechanics of oriented electrospun nanofibrous scaffolds. J Mech Behav Biomed Mater. 2011 ; 4 (8). 1627-1636
22. Efe T, Getgood A, Schofer MD, et al. The safety and short-term efficacy of a novel polyurethane meniscal scaffold for the treatment of segmental medial meniscus deficiency. Knee Surg Sports Traumatol Arthrosc. 2012 ; 20: 1822-1830
23. Eggli S, Wegmuller H, Kosina J, Huckell C, Jakob RP. Long-term results of arthroscopic meniscal repair. An analysis of isolated tears. Am J Sports Med. 1995 ; 23 (6). 715-720
24. Elattar M, Dhollander A, Verdonk R, Almqvist KF, Verdonk P. Twenty-six years of meniscal allograft transplantation: is it still experimental? A meta-analysis of 44 trials. Knee Surg Sports Traumatol Arthrosc. 2011 ; 19 (2). 147-157
25. Fairbank TJ. Knee joint changes after meniscectomy. J Bone Joint Surg Br. 1948 ; 30-B: 664-670
26. Fermor B, Jeffcoat D, Hennerbichler A, Pisetsky DS, Weinberg JB, Guilak F. The effects of cyclic mechanical strain and tumor necrosis factor alpha on the response of cells of the meniscus. Osteoarthritis Cartilage. 2004 ; 12 (12). 956-962 (Pubitemid 39618450)
27. Ferretti M, Madhavan S, Deschner J, Rath-Deschner B, Wypasek E, Agarwal S. Dynamic biophysical strain modulates proinflammatory gene induction in meniscal fibrochondrocytes. Am J Physiol Cell Physiol. 2006 ; 290 (6). C1610-1615
28. Fisher MB, Henning EA, Soegaard N, Esterhai JL, Mauck RL. Organized nanofibrous scaffolds that mimic the macroscopic and microscopic architecture of the knee meniscus. Acta Biomater. 2013 ; 9 (1). 4496-4504
29. Fox DB, Warnock JJ. Cell-based meniscal tissue engineering: a case for synoviocytes. Clin Orthop Relat Res. 2011 ; 469 (10). 2806-2816
30. Galley NK, Gleghorn JP, Rodeo S, Warren RF, Maher SA, Bonassar LJ. Frictional properties of the meniscus improve after scaffold-augmented repair of partial meniscectomy: a pilot study. Clin Orthop Relat Res. 2011 ; 469 (10). 2817-2823
31. Gatehouse PD, He T, Puri BK, Thomas RD, Resnick D, Bydder GM. Contrast-enhanced MRI of the menisci of the knee using ultrashort echo time (UTE) pulse sequences: imaging of the red and white zones. Br J Radiol. 2004 ; 77 (920). 641-647 (Pubitemid 39264324)
32. Graf KW, Sekiya JK, Wojtys EM. Long-term results after combined medial meniscal allograft transplantation and anterior cruciate ligament reconstruction: minimum 8.5-year follow-up study. Arthroscopy. 2004 ; 20 (2). 129-140 (Pubitemid 38233675)
33. Grant JA, Wilde J, Miller BS, Bedi A. Comparison of inside-out and all-inside techniques for the repair of isolated meniscal tears: a systematic review. Am J Sports Med. 2012 ; 40 (2). 459-468
34. Gulotta LV, Wiznia D, Cunningham M, Fortier L, Maher S, Rodeo SA. What's new in orthopaedic research. J Bone Joint Surg Am. 2011 ; 93 (22). 2136-2141
35. Gunja NJ, Athanasiou KA. Passage and reversal effects on gene expression of bovine meniscal fibrochondrocytes. Arthritis Res Ther. 2007 ; 9 (5). R93
36. Gunja NJ, Athanasiou KA. Effects of co-cultures of meniscus cells and articular chondrocytes on PLLA scaffolds. Biotechnol Bioeng. 2009 ; 103 (4). 808-816
37. Gunja NJ, Athanasiou KA. Effects of hydrostatic pressure on leporine meniscus cell-seeded PLLA scaffolds. J Biomed Mater Res A. 2010 ; 92 (3). 896-905
38. Gunja NJ, Uthamanthil RK, Athanasiou KA. Effects of TGF-β1 and hydrostatic pressure on meniscus cell-seeded scaffolds. Biomaterials. 2009 ; 30 (4). 565-573
39. Harston A, Nyland J, Brand E, McGinnis M, Caborn DN. Collagen meniscus implantation: a systematic review including rehabilitation and return to sports activity. Knee Surg Sports Traumatol Arthrosc. 2012 ; 20 (1). 135-146
40. Haut Donahue TL, Hull ML, Rashid MM, Jacobs CR. How the stiffness of meniscal attachments and meniscal material properties affect tibio-femoral contact pressure computed using a validated finite element model of the human knee joint. J Biomech. 2003 ; 36 (1). 19-34 (Pubitemid 35448090)
41. He W, Liu YJ, Wang ZG, Guo ZK, Wang MX, Wang N. Enhancement of meniscal repair in the avascular zone using connective tissue growth factor in a rabbit model. Chin M J. 2011 ; 124 (23). 3968-3975
42. Holloway JL, Lowman AM, Palmese GR. Mechanical evaluation of poly(vinyl alcohol)-based fibrous composites as biomaterials for meniscal tissue replacement. Acta Biomater. 2010 ; 6 (12). 4716-4724
43. Hommen JP, Applegate GR, Del Pizzo W. Meniscus allograft transplantation: ten-year results of cryopreserved allografts. Arthroscopy. 2007 ; 23 (4). 388-393
44. Horie M, Driscoll MD, Sampson HW, et al. Implantation of allogenic synovial stem cells promotes meniscal regeneration in a rabbit meniscal defect model. J Bone Joint Surg Am. 2012 ; 94 (8). 701-712
45. Ishida K, Kuroda R, Miwa M, et al. The regenerative effects of platelet-rich plasma on meniscal cells in vitro and its in vivo application with biodegradable gelatin hydrogel. Tissue Eng. 2007 ; 13 (5). 1103-1112 (Pubitemid 46870434)
46. Kamimura T, Kimura M. Repair of horizontal meniscal cleavage tears with exogenous fibrin clots. Knee Surg Sports Traumatol Arthrosc. 2011 ; 19 (7). 1154-1157
47. Katz JN, Brophy RH, Chaisson CE, et al. Surgery versus physical therapy for a meniscal tear and osteoarthritis. New Engl J Med. 2013 ; 368 (18). 1675-1684
48. Klompmaker J, Jansen HW, Veth RP, Nielsen HK, de Groot JH, Pennings AJ. Porous implants for knee joint meniscus reconstruction: a preliminary study on the role of pore sizes in ingrowth and differentiation of fibrocartilage. Clin Mater. 1993 ; 14 (1). 1-11 (Pubitemid 23247891)
49. Klompmaker J, Veth RP, Jansen HW, Nielsen HK, de Groot JH, Pennings AJ. Meniscal replacement using a porous polymer prosthesis: a preliminary study in the dog. Biomater. 1996 ; 17 (12). 1169-1175 (Pubitemid 26175593)
50. Ko FC, Dragomir C, Plumb DA, et al. In vivo cyclic compression causes cartilage degeneration and subchondral bone changes in mouse tibiae. Arthritis Rheum. 2013 ; 65: 1569-1578
51. Kopf S, Birkenfeld F, Becker R, et al. Local treatment of meniscal lesions with vascular endothelial growth factor. J Bone Joint Surg Am. 2010 ; 92 (16). 2682-2691
52. Kurosawa H, Fukubayashi T, Nakajima H. Load-bearing mode of the knee joint: physical behavior of the knee joint with or without menisci. Clin Orthop Relat Res. 1980 (149). 283-290
53. Lee YH, Caborn DN. A new technique for arthroscopic meniscus transplant using soft tissue fixation and anatomical meniscal root reinsertion. Knee Surg Sports Traumatol Arthrosc. 2012 ; 20 (5). 904-908
54. Loeser RF, Goldring SR, Scanzello CR, Goldring MB. Osteoarthritis: a disease of the joint as an organ. Arthritis Rheum. 2012 ; 64 (6). 1697-1707
55. Lozano J, Ma CB, Cannon WD. All-inside meniscus repair: a systematic review. Clin Orthop Relat Res. 2007 ; 455: 134-141 (Pubitemid 46213722)
56. Lubowitz JH, Verdonk PC, Reid JB, Verdonk R. Meniscus allograft transplantation: a current concepts review. Knee Surg Sports Traumatol Arthrosc. 2007 ; 15 (5). 476-492
57. Maak TG, Fabricant PD, Wickiewicz TL. Indications for meniscus repair. Clin Sports Med. 2012 ; 31 (1). 1-14
58. Makris EA, Hadidi P, Athanasiou KA. The knee meniscus: structure-function, pathophysiology, current repair techniques, and prospects for regeneration. Biomater. 2011 ; 32 (30). 7411-7431
59. McDermott I. Meniscal tears, repairs and replacement: their relevance to osteoarthritis of the knee. Br J Sports Med. 2011 ; 45 (4). 292-297
60. McDermott ID, Lie DT, Edwards A, Bull AM, Amis AA. The effects of lateral meniscal allograft transplantation techniques on tibio-femoral contact pressures. Knee Surg Sports Traumatol Arthrosc. 2008 ; 16 (6). 553-560
61. Miao Y, Yu JK, Ao YF, Zheng ZZ, Gong X, Leung KK. Diagnostic values of 3 methods for evaluating meniscal healing status after meniscal repair: comparison among second-look arthroscopy, clinical assessment, and magnetic resonance imaging. Am J Sports Med. 2011 ; 39 (4). 735-742
62. Monllau JC, Gelber PE, Abat F, et al. Outcome after partial medial meniscus substitution with the collagen meniscal implant at a minimum of 10 years' follow-up. Arthroscopy. 2011 ; 27 (7). 933-943
63. Moriguchi Y, Tateishi K, Ando W, et al. Repair of meniscal lesions using a scaffold-free tissue-engineered construct derived from allogenic synovial MSCs in a miniature swine model. Biomaterials. 2013 ; 34 (9). 2185-2193
64. Moutos FT, Estes BT, Guilak F. Multifunctional hybrid three-dimensionally woven scaffolds for cartilage tissue engineering. Macromol Biosci. 2010 ; 10 (11). 1355-1364
65. Narita A, Takahara M, Ogino T, Fukushima S, Kimura Y, Tabata Y. Effect of gelatin hydrogel incorporating fibroblast growth factor 2 on human meniscal cells in an organ culture model. Knee. 2009 ; 16 (4). 285-289
66. Narita A, Takahara M, Sato D, et al. Biodegradable gelatin hydrogels incorporating fibroblast growth factor 2 promote healing of horizontal tears in rabbit meniscus. Arthroscopy. 2012 ; 28 (2). 255-263
67. Noyes FR, Barber-Westin SD. Management of meniscus tears that extend into the avascular region. Clin Sports Med. 2012 ; 31 (1). 65-90
68. Noyes FR, Heckmann TP, Barber-Westin SD. Meniscus repair and transplantation: a comprehensive update. J Orthop Sports Phys Ther. 2012 ; 42 (3). 274-290
69. Paxton ES, Stock MV, Brophy RH. Meniscal repair versus partial meniscectomy: a systematic review comparing reoperation rates and clinical outcomes. Arthroscopy. 2011 ; 27 (9). 1275-1288
70. Piontek T, Ciemniewska-Gorzela K, Szulc A, Slomczykowski M, Jakob R. All-arthroscopic technique of biological meniscal tear therapy with collagen matrix. Pol Orthop Traumatol. 2012 ; 77: 39-45
71. Potter HG, Chong le R. Magnetic resonance imaging assessment of chondral lesions and repair. J Bone Joint Surg Am. 2009 ; 91: 126-131
72. Puetzer JL, Brown B, Ballyns JJ, Bonassar LJ. The effect of IGF-I on anatomically-shaped tissue engineered menisci. Tissue Eng Part A. 2013 ; 19: 1443-1450
73. Rath E, Richmond JC, Yassir W, Albright JD, Gundogan F. Meniscal allograft transplantation. Two- to eight-year results. Am J Sports Med. 2001 ; 29 (4). 410-414 (Pubitemid 32661354)
74. Reguzzoni M, Manelli A, Ronga M, Raspanti M, Grassi FA. Histology and ultrastructure of a tissue-engineered collagen meniscus before and after implantation. J Biomed Mater Res B Appl Biomater. 2005 ; 74 (2). 808-816 (Pubitemid 41076953)
75. Revell CM, Athanasiou KA. Success rates and immunologic responses of autogenic, allogenic, and xenogenic treatments to repair articular cartilage defects. Tissue Eng Part B. 2009 ; 15 (1). 1-15
76. Rodeo SA. Meniscal allografts - where do we stand?. Am J Sports Med. 2001 ; 29 (2). 246-261 (Pubitemid 32231044)
77. Rodeo SA, Seneviratne A, Suzuki K, Felker K, Wickiewicz TL, Warren RF. Histological analysis of human meniscal allografts. A preliminary report. J Bone Joint Surg Am. 2000 ; 82 (8). 1071-1082 (Pubitemid 30624964)
78. Rodkey WG, DeHaven KE, Montgomery WH, et al. Comparison of the collagen meniscus implant with partial meniscectomy. A prospective randomized trial. J Bone Joint Surg Am. 2008 ; 90 (7). 1413-1426 (Pubitemid 351947581)
79. Ronga M, Grassi FA, Manelli A, Bulgheroni P. Tissue engineering techniques for the treatment of a complex knee injury. Arthroscopy. 2006 ; 22 (5). 576 - e571-573
80. Roos H, Lauren M, Adalberth T, Roos EM, Jonsson K, Lohmander LS. Knee osteoarthritis after meniscectomy: prevalence of radiographic changes after twenty-one years, compared with matched controls. Arthritis Rheum. 1998 ; 41 (4). 687-693 (Pubitemid 28214987)
81. Ruiz-Iban MA, Diaz-Heredia J, Elias-Martin E, Moros-Marco S, Cebreiro Martinez Del Val I. Repair of meniscal tears associated with tibial plateau fractures: a review of 15 cases. Am J Sports Med. 2012 ; 40: 2289-2295
82. Saltzman BM, Bajaj S, Salata M, et al. Prospective long-term evaluation of meniscal allograft transplantation procedure: a minimum of 7-year follow-up. J Knee Surg. 2012 ; 25 (2). 165-175
83. Scotti C, Mangiavini L, Boschetti F, et al. Effect of in vitro culture on a chondrocyte-fibrin glue hydrogel for cartilage repair. Knee Surg Sports Traumatol Arthrosc. 2010 ; 18 (10). 1400-1406
84. Spencer SJ, Saithna A, Carmont MR, Dhillon MS, Thompson P, Spalding T. Meniscal scaffolds: Early experience and review of the literature. Knee. 2012 ; 19 (6). 760-765
85. Spilker RL, Donzelli PS, Mow VC. A transversely isotropic biphasic finite element model of the meniscus. J Biomech. 1992 ; 25 (9). 1027-1045
86. Stabile KJ, Odom D, Smith TL, et al. An acellular, allograft-derived meniscus scaffold in an ovine model. Arthroscopy. 2010 ; 26 (7). 936-948
87. Steadman JR, Rodkey WG. Tissue-engineered collagen meniscus implants: 5- to 6-year feasibility study results. Arthroscopy. 2005 ; 21 (5). 515-525 (Pubitemid 40712210)
88. Steinert AF, Palmer GD, Pilapil C, Noth U, Evans CH, Ghivizzani SC. Enhanced in vitro chondrogenesis of primary mesenchymal stem cells by combined gene transfer. Tissue Eng Part A. 2009 ; 15 (5). 1127-1139
89. Steinert AF, Weissenberger M, Kunz M, et al. Indian hedgehog gene transfer is a chondrogenic inducer of human mesenchymal stem cells. Arthritis Res Ther. 2012 ; 14 (4). R168
90. Stone KR, Steadman JR, Rodkey WG, Li ST. Regeneration of meniscal cartilage with use of a collagen scaffold. Analysis of preliminary data. J Bone Joint Surg Am. 1997 ; 79 (12). 1770-1777 (Pubitemid 28016581)
91. Taylor SA, Rodeo SA. Augmentation techniques for isolated meniscal tears. Curr Rev Musculoskelet Med. 2013 ; 6: 95-101
92. van der Wal RJ, Thomassen BJ, van Arkel ER. Long-term clinical outcome of open meniscal allograft transplantation. Am J Sports Med. 2009 ; 37 (11). 2134-2139
93. van Trommel MF, Potter HG, Ernberg LA, Simonian PT, Wickiewicz TL. The use of noncontrast magnetic resonance imaging in evaluating meniscal repair: comparison with conventional arthrography. Arthroscopy. 1998 ; 14 (1). 2-8 (Pubitemid 28099274)
94. van Trommel MF, Simonian PT, Potter HG, Wickiewicz TL. Different regional healing rates with the outside-in technique for meniscal repair. Am J Sports Med. 1998 ; 26 (3). 446-452 (Pubitemid 28248739)
95. Venkatachalam S, Godsiff SP, Harding ML. Review of the clinical results of arthroscopic meniscal repair. Knee. 2001 ; 8 (2). 129-133 (Pubitemid 32405247)
96. Verdonk P, Beaufils P, Bellemans J, et al. Successful treatment of painful irreparable partial meniscal defects with a polyurethane scaffold: two-year safety and clinical outcomes. Am J Sports Med. 2012 ; 40: 844-853
97. Verdonk PC, Demurie A, Almqvist KF, Veys EM, Verbruggen G, Verdonk R. Transplantation of viable meniscal allograft. Survivorship analysis and clinical outcome of one hundred cases. J Bone Joint Surg Am. 2005 ; 87 (4). 715-724 (Pubitemid 40489345)
98. Verdonk PC, Verstraete KL, Almqvist KF, et al. Meniscal allograft transplantation: long-term clinical results with radiological and magnetic resonance imaging correlations. Knee Surg Sports Traumatol Arthrosc. 2006 ; 14 (8). 694-706 (Pubitemid 44598200)
99. Verdonk R, Verdonk P, Huysse W, Forsyth R, Heinrichs EL. Tissue ingrowth after implantation of a novel, biodegradable polyurethane scaffold for treatment of partial meniscal lesions. Am J Sports Med. 2011 ; 39 (4). 774-782
100. von Lewinski G, Milachowski KA, Weismeier K, Kohn D, Wirth CJ. Twenty-year results of combined meniscal allograft transplantation, anterior cruciate ligament reconstruction and advancement of the medial collateral ligament. Knee Surg Sports Traumatol Arthrosc. 2007 ; 15 (9). 1072-1082
101. Vundelinckx B, Bellemans J, Vanlauwe J. Arthroscopically assisted meniscal allograft transplantation in the knee: a medium-term subjective, clinical, and radiographical outcome evaluation. Am J Sports Med. 2010 ; 38 (11). 2240-2247
102. Wang YX, Griffith JF, Ahuja AT. Non-invasive MRI assessment of the articular cartilage in clinical studies and experimental settings. World J Radiol. 2010 ; 2 (1). 44-54
103. Weibrich G, Kleis WK, Streckbein P, Moergel M, Hitzler WE, Hafner G. Comparison of point-of-care methods for preparation of platelet concentrate (platelet-rich plasma). Int J Oral Maxillofac Implants. 2012 ; 27 (4). 762-769
104. Weinand C, Peretti GM, Adams SB, Bonassar LJ, Randolph MA, Gill TJ. An allogenic cell-based implant for meniscal lesions. Am J Sports Med. 2006 ; 34 (11). 1779-1789 (Pubitemid 44735518)
105. Welsing RT, van Tienen TG, Ramrattan N, et al. Effect on tissue differentiation and articular cartilage degradation of a polymer meniscus implant: a 2-year follow-up study in dogs. Am J Sports Med. 2008 ; 36 (10). 1978-1989
106. Wirth CJ, Peters G, Milachowski KA, Weismeier KG, Kohn D. Long-term results of meniscal allograft transplantation. Am J Sports Med. 2002 ; 30 (2). 174-181 (Pubitemid 34241255)
107. Zaffagnini S, Marcheggiani Muccioli GM, Bulgheroni P, et al. Arthroscopic collagen meniscus implantation for partial lateral meniscal defects: a 2-year minimum follow-up study. Am J Sports Med. 2012 ; 40: 2281-2288
108. Zaffagnini S, Marcheggiani Muccioli GM, Lopomo N, et al. Prospective long-term outcomes of the medial collagen meniscus implant versus partial medial meniscectomy: a minimum 10-year follow-up study. Am J Sports Med. 2011 ; 39 (5). 977-985
109. Zellner J, Mueller M, Berner A, et al. Role of mesenchymal stem cells in tissue engineering of meniscus. J Biomed Mater Res A. 2010 ; 94 (4). 1150-1161
110. Zhang Z, Arnold JA, Williams T, McCann B. Repairs by trephination and suturing of longitudinal injuries in the avascular area of the meniscus in goats. Am J Sports Med. 1995 ; 23 (1). 35-41
111. Zur G, Linder-Ganz E, Elsner JJ, et al. Chondroprotective effects of a polycarbonate-urethane meniscal implant: histopathological results in a sheep model. Knee Surg Sports Traumatol Arthrosc. 2011 ; 19 (2). 255-263