PIM1 regulates glycolysis and promotes tumor progression in hepatocellular carcinoma

Oncotarget

Volumn 6, Issue 13, 2015, Pages 10880-10892

  Leung, Carmen Oi ning ^a   Wong, Carmen Chak lui ^a,b   Fan, Dorothy Ngo yin ^a   Kai, Alan Ka lun ^a   Tung, Edmund Kwok kwan ^a   Xu, Iris Ming jing ^a   Ng, Irene Oi lin ^a,b   Lo, Regina Cheuk lam ^a,b  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

^b THE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

HCC; Metastasis; PIM1

Indexed keywords

CARBONATE DEHYDRATASE IX; GLUCOSE TRANSPORTER 1; HYPOXIA INDUCIBLE FACTOR 1ALPHA; PROTEASOME; PROTEIN KINASE B; PROTEIN KINASE PIM 1; HIF1A PROTEIN, HUMAN; PIM1 PROTEIN, HUMAN;

ADRENAL METASTASIS; ADULT; AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN METASTASIS; CELL HYPOXIA; CELL PROLIFERATION; COHORT ANALYSIS; CONTROLLED STUDY; ENZYME DEGRADATION; ENZYME PHOSPHORYLATION; EPITHELIAL MESENCHYMAL TRANSITION; FEMALE; GLUCOSE TRANSPORT; GLYCOLYSIS; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; LIVER CELL CARCINOMA; LUNG METASTASIS; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; METASTASIS POTENTIAL; MIDDLE AGED; MOUSE; NONHUMAN; PERITONEUM METASTASIS; PORTAL VEIN THROMBOSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; TUMOR GROWTH; TUMOR INVASION; UPREGULATION; VERY ELDERLY; ACTIVE TRANSPORT; ANIMAL; CELL MOTION; DISEASE COURSE; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENE SILENCING; GENETIC TRANSFECTION; GENETICS; LIVER TUMOR; METABOLISM; NUDE MOUSE; PATHOLOGY; PHOSPHORYLATION; PROTEIN DEGRADATION; RNA INTERFERENCE; SECONDARY; SIGNAL TRANSDUCTION; TIME FACTOR; TUMOR CELL LINE; TUMOR VOLUME;

ACTIVE TRANSPORT, CELL NUCLEUS; AGED; AGED, 80 AND OVER; ANIMALS; CARCINOMA, HEPATOCELLULAR; CELL HYPOXIA; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; DISEASE PROGRESSION; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE KNOCKDOWN TECHNIQUES; GLYCOLYSIS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; LIVER NEOPLASMS; MALE; MICE, NUDE; MIDDLE AGED; NEOPLASM INVASIVENESS; PHOSPHORYLATION; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEOLYSIS; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-PIM-1; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TIME FACTORS; TRANSFECTION; TUMOR BURDEN; UP-REGULATION;

EID: 84929650187     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.3534     Document Type: Article

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