Expression and contributions of the Kir2.1 inward-rectifier K+ channel to proliferation, migration and chemotaxis of microglia in unstimulated and anti-inflammatory states

Frontiers in Cellular Neuroscience

Volumn 9, Issue MAY, 2015, Pages

  Lam, Doris ^a,b   Schlichter, Lyanne C ^a,b  

^a UNIVERSITY HEALTH NETWORK   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

Acquired deactivated microglia; Alternative activated microglia; Interleukin 10 stimulation; Interleukin 4 stimulation; KCNJ2; Microglial migration; Microglial proliferation; ML133

Indexed keywords

AGITOXIN 2; CHEMOATTRACTANT; INTERLEUKIN 10; INTERLEUKIN 4; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR2.1; ION TRANSPORT AFFECTING AGENT; ML 133; POTASSIUM CHANNEL BLOCKING AGENT; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL ACTIVATION; CELL MEMBRANE DEPOLARIZATION; CELL MIGRATION; CELL MIGRATION ASSAY; CELL PROLIFERATION; CELL STRUCTURE; CELL VIABILITY; CHEMOTAXIS; CONTROLLED STUDY; DRUG EFFICACY; ELECTRON MICROSCOPY; IC50; MEMBRANE POTENTIAL; MICROGLIA; NONHUMAN; PATCH CLAMP TECHNIQUE; POTASSIUM CURRENT; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; RNA EXTRACTION; SIGNAL TRANSDUCTION; TRANSWELL MIGRATION ASSAY;

EID: 84929593923     PISSN: 16625102     EISSN: None     Source Type: Journal    
DOI: 10.3389/fncel.2015.00185     Document Type: Article

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