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note
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Kinetic resolution of 998 mg of the compound in Table 2, entry 1: s = 10 with 52% conversion and recovered alcohol with an er of 85:15.
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note
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Conversions and selectivity factors are based on the ee of the recovered starting materials and products. Percent conversion = ees/(ees + eep) × 100% and s = ln[(1-C)(1-ees)]/ln[(1-C)(1 + ees)], where ees = ee of recovered starting material and eep = ee of product. See ref 3a.
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Selectivity factors are an average of two runs. Conversions are from a single run.
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