-
1
-
-
0037129380
-
Nonalcoholic fatty liver disease
-
Angulo P. Nonalcoholic fatty liver disease. N Engl J Med 2002; 346: 1221-31
-
(2002)
N Engl J Med
, vol.346
, pp. 1221-1231
-
-
Angulo, P.1
-
2
-
-
84880419922
-
Non-alcoholic steatohepatitis: Pathogenesis and novel therapeutic approaches
-
Schuppan D, Schattenberg JM. Non-alcoholic steatohepatitis: pathogenesis and novel therapeutic approaches. J Gastroenterol Hepatol 2013; 28(Suppl. 1): 68-76
-
(2013)
J Gastroenterol Hepatol
, vol.28
, pp. 68-76
-
-
Schuppan, D.1
Schattenberg, J.M.2
-
3
-
-
79960029926
-
Systematic review: The epidemiology and natural history of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis in adults
-
Vernon G, Baranova A, Younossi ZM. Systematic review: the epidemiology and natural history of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis in adults. Aliment Pharmacol Ther 2011; 34: 274-285
-
(2011)
Aliment Pharmacol Ther
, vol.34
, pp. 274-285
-
-
Vernon, G.1
Baranova, A.2
Younossi, Z.M.3
-
4
-
-
84893696694
-
The prevalence of nonalcoholic fatty liver disease in the Americas
-
Lopez-Velazquez JA, Silva-Vidal KV, Ponciano-Rodriguez G, Chavez-Tapia NC, Arrese M, Uribe M, Mendez-Sanchez N. The prevalence of nonalcoholic fatty liver disease in the Americas. Ann Hepatol 2014; 13: 166-78
-
(2014)
Ann Hepatol
, vol.13
, pp. 166-178
-
-
Lopez-Velazquez, J.A.1
Silva-Vidal, K.V.2
Ponciano-Rodriguez, G.3
Chavez-Tapia, N.C.4
Arrese, M.5
Uribe, M.6
Mendez-Sanchez, N.7
-
5
-
-
57749183469
-
Prevalence and associated factors of non-alcoholic fatty liver disease in patients with type-2 diabetes mellitus
-
Leite NC, Salles GF, Araujo AL, Villela-Nogueira CA, Cardoso CR. Prevalence and associated factors of non-alcoholic fatty liver disease in patients with type-2 diabetes mellitus. Liver Int 2009; 29: 113-9
-
(2009)
Liver Int
, vol.29
, pp. 113-119
-
-
Leite, N.C.1
Salles, G.F.2
Araujo, A.L.3
Villela-Nogueira, C.A.4
Cardoso, C.R.5
-
6
-
-
33846473612
-
Nonalcoholic fatty liver disease in severely obese subjects
-
Gholam PM, Flancbaum L, Machan JT, Charney DA, Kotler DP. Nonalcoholic fatty liver disease in severely obese subjects. Am J Gastroenterol 2007; 102: 399-408
-
(2007)
Am J Gastroenterol
, vol.102
, pp. 399-408
-
-
Gholam, P.M.1
Flancbaum, L.2
Machan, J.T.3
Charney, D.A.4
Kotler, D.P.5
-
7
-
-
0033739433
-
Fatty infiltration of liver in hyperlipidemic patients
-
Assy N, Kaita K, Mymin D, Levy C, Rosser B, Minuk G. Fatty infiltration of liver in hyperlipidemic patients. Dig Dis Sci 2000; 45: 1929-34
-
(2000)
Dig Dis Sci
, vol.45
, pp. 1929-1934
-
-
Assy, N.1
Kaita, K.2
Mymin, D.3
Levy, C.4
Rosser, B.5
Minuk, G.6
-
8
-
-
34047192773
-
Current concepts in the pathogenesis of nonalcoholic fatty liver disease
-
Mendez-Sanchez N, Arrese M, Zamora-Valdes D, Uribe M. Current concepts in the pathogenesis of nonalcoholic fatty liver disease. Liver Int 2007; 27: 423-33
-
(2007)
Liver Int
, vol.27
, pp. 423-433
-
-
Mendez-Sanchez, N.1
Arrese, M.2
Zamora-Valdes, D.3
Uribe, M.4
-
10
-
-
84887477319
-
Bile acid receptors in non-alcoholic fatty liver disease
-
Li Y, Jadhav K, Zhang Y. Bile acid receptors in non-alcoholic fatty liver disease. Biochem Pharmacol 2013; 86: 1517-24
-
(2013)
Biochem Pharmacol
, vol.86
, pp. 1517-1524
-
-
Li, Y.1
Jadhav, K.2
Zhang, Y.3
-
11
-
-
58249110568
-
Role of bile acids and bile acid receptors in metabolic regulation
-
Lefebvre P, Cariou B, Lien F, Kuipers F, Staels B. Role of bile acids and bile acid receptors in metabolic regulation. Physiol Rev 2009; 89: 147-91
-
(2009)
Physiol Rev
, vol.89
, pp. 147-191
-
-
Lefebvre, P.1
Cariou, B.2
Lien, F.3
Kuipers, F.4
Staels, B.5
-
12
-
-
84865484646
-
Anti-inflammatory and metabolic actions of FXR: Insights into molecular mechanisms
-
Hollman DA, Milona A, van Erpecum KJ, van Mil SW. Anti-inflammatory and metabolic actions of FXR: insights into molecular mechanisms. Biochim Biophys Acta 2012; 1821: 1443-52
-
(2012)
Biochim Biophys Acta
, vol.1821
, pp. 1443-1452
-
-
Hollman, D.A.1
Milona, A.2
Van Erpecum, K.J.3
Van Mil, S.W.4
-
13
-
-
79956088562
-
The bile acid membrane receptor TGR5 as an emerging target in metabolism and inflammation
-
Pols TW, Noriega LG, Nomura M, Auwerx J, Schoonjans K. The bile acid membrane receptor TGR5 as an emerging target in metabolism and inflammation. J Hepatol 2011; 54: 1263-72
-
(2011)
J Hepatol
, vol.54
, pp. 1263-1272
-
-
Pols, T.W.1
Noriega, L.G.2
Nomura, M.3
Auwerx, J.4
Schoonjans, K.5
-
14
-
-
79955052166
-
Elevated hepatic fatty acid oxidation, high plasma fibroblast growth factor 21, and fasting bile acids in nonalcoholic steatohepatitis
-
Dasarathy S, Yang Y, McCullough AJ, Marczewski S, Bennett C, Kalhan SC. Elevated hepatic fatty acid oxidation, high plasma fibroblast growth factor 21, and fasting bile acids in nonalcoholic steatohepatitis. Eur J Gastroenterol Hepatol 2011; 23: 382-8
-
(2011)
Eur J Gastroenterol Hepatol
, vol.23
, pp. 382-388
-
-
Dasarathy, S.1
Yang, Y.2
McCullough, A.J.3
Marczewski, S.4
Bennett, C.5
Kalhan, S.C.6
-
15
-
-
43449094989
-
Bile acid levels are increased in the liver of patients with steatohepatitis
-
Aranha MM, Cortez-Pinto H, Costa A, da Silva IB, Camilo ME, de Moura MC, Rodrigues CM. Bile acid levels are increased in the liver of patients with steatohepatitis. Eur J Gastroenterol Hepatol 2008; 20: 519-25
-
(2008)
Eur J Gastroenterol Hepatol
, vol.20
, pp. 519-525
-
-
Aranha, M.M.1
Cortez-Pinto, H.2
Costa, A.3
Da Silva, I.B.4
Camilo, M.E.5
De Moura, M.C.6
Rodrigues, C.M.7
-
16
-
-
79953173235
-
Nuclear receptors as new perspective for the management of liver diseases
-
Trauner M, Halilbasic E. Nuclear receptors as new perspective for the management of liver diseases. Gastroenterology 2011; 140: 1120-1125
-
(2011)
Gastroenterology
, vol.140
, pp. 1120-1125
-
-
Trauner, M.1
Halilbasic, E.2
-
21
-
-
53349153430
-
Liver X receptor in cooperation with SREBP-1c is a major lipid synthesis regulator in nonalcoholic fatty liver disease
-
Higuchi N, Kato M, Shundo Y, Tajiri H, Tanaka M, Yamashita N, Kohjima M, et al. Liver X receptor in cooperation with SREBP-1c is a major lipid synthesis regulator in nonalcoholic fatty liver disease. Hepatol Res 2008; 38: 1122-9
-
(2008)
Hepatol Res
, vol.38
, pp. 1122-1129
-
-
Higuchi, N.1
Kato, M.2
Shundo, Y.3
Tajiri, H.4
Tanaka, M.5
Yamashita, N.6
Kohjima, M.7
-
22
-
-
20044374023
-
Design and validation of a histological scoring system for nonalcoholic fatty liver disease
-
Kleiner DE, Brunt EM, Van Natta M, Behling C, Contos MJ, Cummings OW, Ferrell LD, et al. Design and validation of a histological scoring system for nonalcoholic fatty liver disease. Hepatology 2005; 41: 1313-21
-
(2005)
Hepatology
, vol.41
, pp. 1313-1321
-
-
Kleiner, D.E.1
Brunt, E.M.2
Van Natta, M.3
Behling, C.4
Contos, M.J.5
Cummings, O.W.6
Ferrell, L.D.7
-
23
-
-
0043192611
-
Selection of optimal internal controls for gene expression profiling of liver disease
-
Kim S, Kim T. Selection of optimal internal controls for gene expression profiling of liver disease. Biotechniques 2003; 35: 456-58, 460
-
(2003)
Biotechniques
, vol.35
, Issue.460
, pp. 456-458
-
-
Kim, S.1
Kim, T.2
-
24
-
-
27444434833
-
Role of nuclear receptors and hepatocyte-enriched transcription factors for Ntcp repression in biliary obstruction in mouse liver
-
Zollner G, Wagner M, Fickert P, Geier A, Fuchsbichler A, Silbert D, Gumhold J, et al. Role of nuclear receptors and hepatocyte-enriched transcription factors for Ntcp repression in biliary obstruction in mouse liver. Am J Physiol Gastrointest Liver Physiol 2005; 289: G798-G805
-
(2005)
Am J Physiol Gastrointest Liver Physiol
, vol.289
-
-
Zollner, G.1
Wagner, M.2
Fickert, P.3
Geier, A.4
Fuchsbichler, A.5
Silbert, D.6
Gumhold, J.7
-
25
-
-
37249015421
-
Differential regulation of bile acid homeostasis by the farnesoid X receptor in liver and intestine
-
Kim I, Ahn SH, Inagaki T, Choi M, Ito S, Guo GL, Kliewer SA, et al. Differential regulation of bile acid homeostasis by the farnesoid X receptor in liver and intestine. J Lipid Res 2007; 48: 2664-72
-
(2007)
J Lipid Res
, vol.48
, pp. 2664-2672
-
-
Kim, I.1
Ahn, S.H.2
Inagaki, T.3
Choi, M.4
Ito, S.5
Guo, G.L.6
Kliewer, S.A.7
-
26
-
-
84896388318
-
Hepatic steatosis exacerbated by endoplasmic reticulum stress-mediated down regulation of FXR in aging mice
-
Xiong X, Wang X, Lu Y, Wang E, Zhang Z, Yang J, Zhang H, et al. Hepatic steatosis exacerbated by endoplasmic reticulum stress-mediated down regulation of FXR in aging mice. J Hepatol 2014; 60: 847-54
-
(2014)
J Hepatol
, vol.60
, pp. 847-854
-
-
Xiong, X.1
Wang, X.2
Lu, Y.3
Wang, E.4
Zhang, Z.5
Yang, J.6
Zhang, H.7
-
27
-
-
78649475438
-
Effects of nuclear receptor FXR on the regulation of liver lipid metabolism in patients with non-alcoholic fatty liver disease
-
Yang ZX, Shen W, Sun H. Effects of nuclear receptor FXR on the regulation of liver lipid metabolism in patients with non-alcoholic fatty liver disease. Hepatol Int 2010; 4: 741-8
-
(2010)
Hepatol Int
, vol.4
, pp. 741-748
-
-
Yang, Z.X.1
Shen, W.2
Sun, H.3
-
28
-
-
79955554762
-
Animal models for the study of liver fibrosis: New insights from knockout mouse models
-
Hayashi H, Sakai T. Animal models for the study of liver fibrosis: new insights from knockout mouse models. Am J Physiol Gastrointest Liver Physiol 2011; 300: G729-G738
-
(2011)
Am J Physiol Gastrointest Liver Physiol
, vol.300
-
-
Hayashi, H.1
Sakai, T.2
-
29
-
-
84859404868
-
Role of obesity and lipotoxicity in the development of nonalcoholic steatohepatitis: Pathophysiology and clinical implications
-
Cusi K. Role of obesity and lipotoxicity in the development of nonalcoholic steatohepatitis: pathophysiology and clinical implications. Gastroenterology 2012; 142: 711-25 e716
-
(2012)
Gastroenterology
, vol.142
, pp. 711-725
-
-
Cusi, K.1
-
30
-
-
67649210759
-
Farnesoid X receptor agonist WAY-362450 attenuates liver inflammation and fi fibrosis in murine model of non-alcoholic steatohepatitis
-
Zhang S, Wang J, Liu Q, Harnish DC. Farnesoid X receptor agonist WAY-362450 attenuates liver inflammation and fi fibrosis in murine model of non-alcoholic steatohepatitis. J Hepatol 2009; 51: 380-8
-
(2009)
J Hepatol
, vol.51
, pp. 380-388
-
-
Zhang, S.1
Wang, J.2
Liu, Q.3
Harnish, D.C.4
-
31
-
-
0032732615
-
Modulation by drugs of human hepatic sodium-dependent bile acid transporter (Sodium taurocholate cotransporting polypeptide) activity
-
Kim RB, Leake B, Cvetkovic M, Roden MM, Nadeau J, Walubo A, Wilkinson GR. Modulation by drugs of human hepatic sodium-dependent bile acid transporter (sodium taurocholate cotransporting polypeptide) activity. J Pharmacol Exp Ther 1999; 291: 1204-9
-
(1999)
J Pharmacol Exp Ther
, vol.291
, pp. 1204-1209
-
-
Kim, R.B.1
Leake, B.2
Cvetkovic, M.3
Roden, M.M.4
Nadeau, J.5
Walubo, A.6
Wilkinson, G.R.7
-
32
-
-
84876146580
-
Free fatty acids repress small heterodimer partner (SHP) activation and adiponectin counteracts bile acid-induced liver injury in superobese patients with nonalcoholic steatohepatitis
-
Bechmann LP, Kocabayoglu P, Sowa JP, Sydor S, Best J, Schlattjan M, Beilfuss A, et al. Free fatty acids repress small heterodimer partner (SHP) activation and adiponectin counteracts bile acid-induced liver injury in superobese patients with nonalcoholic steatohepatitis. Hepatology 2013; 57: 1394-406
-
(2013)
Hepatology
, vol.57
, pp. 1394-1406
-
-
Bechmann, L.P.1
Kocabayoglu, P.2
Sowa, J.P.3
Sydor, S.4
Best, J.5
Schlattjan, M.6
Beilfuss, A.7
-
33
-
-
68949205722
-
Correlations between RNA and protein expression profiles in 23 human cell lines
-
Gry M, Rimini R, Stromberg S, Asplund A, Ponten F, Uhlen M, Nilsson P. Correlations between RNA and protein expression profiles in 23 human cell lines. BMC Genomics 2009; 10: 365
-
(2009)
BMC Genomics
, vol.10
-
-
Gry, M.1
Rimini, R.2
Stromberg, S.3
Asplund, A.4
Ponten, F.5
Uhlen, M.6
Nilsson, P.7
-
34
-
-
84901611036
-
Mass-spectrometry- based draft of the human proteome
-
Wilhelm M, Schlegl J, Hahne H, Moghaddas Gholami A, Lieberenz M, Savitski MM, Ziegler E, et al. Mass-spectrometry- based draft of the human proteome. Nature 2014; 509: 582-7
-
(2014)
Nature
, vol.509
, pp. 582-587
-
-
Wilhelm, M.1
Schlegl, J.2
Hahne, H.3
Moghaddas Gholami, A.4
Lieberenz, M.5
Savitski, M.M.6
Ziegler, E.7
-
35
-
-
84893276590
-
Analysis of the human tissue-specific expression by genome-wide integration of transcriptomics and antibody-based proteomics
-
Fagerberg L, Hallstrom BM, Oksvold P, Kampf C, Djureinovic D, Odeberg J, Habuka M, et al. Analysis of the human tissue-specific expression by genome-wide integration of transcriptomics and antibody-based proteomics. Mol Cell Proteomics 2014; 13: 397-406
-
(2014)
Mol Cell Proteomics
, vol.13
, pp. 397-406
-
-
Fagerberg, L.1
Hallstrom, B.M.2
Oksvold, P.3
Kampf, C.4
Djureinovic, D.5
Odeberg, J.6
Habuka, M.7
-
36
-
-
84858439862
-
Insights into the regulation of protein abundance from proteomic and transcriptomic analyses
-
Vogel C, Marcotte EM. Insights into the regulation of protein abundance from proteomic and transcriptomic analyses. Nat Rev Genet 2012; 13: 227-32.
-
(2012)
Nat Rev Genet
, vol.13
, pp. 227-232
-
-
Vogel, C.1
Marcotte, E.M.2
|