The adult murine heart has a sparse, phagocytically active macrophage population that expands through monocyte recruitment and adopts an 'M2' phenotype in response to Th2 immunologic challenge

Immunobiology

Volumn 220, Issue 7, 2015, Pages 924-933

  Mylonas, Katie J ^a   Jenkins, Stephen J ^b   Castellan, Raphael F P ^a   Ruckerl, Dominik ^b   McGregor, Kieran ^a   Phythian Adams, Alexander T ^b,c   Hewitson, James P ^b   Campbell, Sharon M ^b   MacDonald, Andrew S ^b,c   Allen, Judith E ^b   Gray, Gillian A ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

^c UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

Heart; Helminth infection; Macrophage

Indexed keywords

ARG 1 PROTEIN; BIOLOGICAL MARKER; CHEMOKINE RECEPTOR CCR2; INTERLEUKIN 1BETA; MANNOSE RECEPTOR; PROTEIN RELMALPHA; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; YM1 PROTEIN; BETA N ACETYLHEXOSAMINIDASE; CD11B ANTIGEN; CELL SURFACE RECEPTOR; CHEMOKINE RECEPTOR; CHI3L3 PROTEIN, MOUSE; COLONY STIMULATING FACTOR RECEPTOR; CX3CR1 PROTEIN, MOUSE; DIFFERENTIATION ANTIGEN; GREEN FLUORESCENT PROTEIN; LECTIN; MANNOSE BINDING LECTIN; MONOCYTE-MACROPHAGE DIFFERENTIATION ANTIGEN; RETNLA PROTEIN, MOUSE; SIGNAL PEPTIDE;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DENSITY; CELL POLARITY; CELL POPULATION; CELL STRUCTURE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; HEART MUSCLE; HELIGMOSOMOIDES POLYGYRUS; MACROPHAGE ACTIVATION; MONOCYTE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SCHISTOSOMIASIS MANSONI; STELLATE CELL; STRONGYLE INFECTION; TH2 CELL; ANIMAL; BIOSYNTHESIS; CARDIAC MUSCLE; GENETICS; HEART; IMMUNOLOGY; KNOCKOUT MOUSE; MACROPHAGE; METABOLISM; PARASITOLOGY; PHAGOCYTOSIS; SCHISTOSOMA MANSONI;

ANIMALS; ANTIGENS, CD11B; ANTIGENS, DIFFERENTIATION; BETA-N-ACETYLHEXOSAMINIDASES; GREEN FLUORESCENT PROTEINS; HEART; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LECTINS; LECTINS, C-TYPE; MACROPHAGES; MANNOSE-BINDING LECTINS; MICE; MICE, KNOCKOUT; MYOCARDIUM; NEMATOSPIROIDES DUBIUS; PHAGOCYTOSIS; RECEPTOR, MACROPHAGE COLONY-STIMULATING FACTOR; RECEPTORS, CELL SURFACE; RECEPTORS, CHEMOKINE; SCHISTOSOMA MANSONI; SCHISTOSOMIASIS MANSONI; STRONGYLIDA INFECTIONS; TH2 CELLS;

EID: 84929505763     PISSN: 01712985     EISSN: 18783279     Source Type: Journal    
DOI: 10.1016/j.imbio.2015.01.013     Document Type: Article

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