Monocyte chemotactic protein-1 stimulates the killing of Leishmania major by human monocytes, acts synergistically with IFN-γ and is antagonized by IL-4

European Journal of Immunology

Volumn 30, Issue 11, 2000, Pages 3111-3120

  Ritter, Uwe ^a,b   Moll, Heidrun ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

Antimicrobial mechanism; Chemokine; Human monocyte; Infectious immunity parasite

Indexed keywords

CHEMOKINE; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 4; MACROPHAGE INFLAMMATORY PROTEIN; MONOCYTE CHEMOTACTIC PROTEIN 1; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; REACTIVE OXYGEN METABOLITE; SUPEROXIDE;

ANTIMICROBIAL ACTIVITY; ARTICLE; CHRONICITY; CONTROLLED STUDY; CYTOKINE RELEASE; DISEASE COURSE; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; LEISHMANIA MAJOR; LEUKOCYTE ACTIVATION; MACROPHAGE ACTIVATION; MONOCYTE; PARASITE CONTROL; PRIORITY JOURNAL; SKIN LEISHMANIASIS; TH1 CELL; TH2 CELL;

ANIMALS; CELLS, CULTURED; CHEMOKINE CCL2; DRUG ANTAGONISM; DRUG SYNERGISM; HUMANS; INTERFERON TYPE II; INTERLEUKIN-4; LEISHMANIA MAJOR; MONOCYTES; PHAGOCYTOSIS; SIGNAL TRANSDUCTION;

EID: 0033738823     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-4141(200011)30:11<3111::AID-IMMU3111>3.0.CO;2-O     Document Type: Article

References (36)

1. Determination of the cytokine profile in American cutaneous leishmaniasis using the polymerase chain reaction
2. Increased expression of pro-inflammatory cytokines in chronic lesions of human cutaneous leishmaniasis
3. Differential expression of chemokines in patients with localized and diffuse cutaneous American leishmaniasis
4. The biology of chemokines and their receptors
5. Induction of natural killer cell migration by monocyte chemotactic protein-1, -2 and -3
6. Regulation of dendritic cell trafficking: A process that involves the participation of selective chemokines
7. Recombinant human MCP-1/JE induces chemotaxis, calcium flux, and the respiratory burst in human monocytes
8. Macrophage inflammatory protein 1 modulates macrophage function
9. A reliable method for simultaneous demonstration of two antigens using a novel combination of immunogold-silver staining and immunoenzymatic labeling
10. Effect of lipopolysaccharide on intracellular killing of Leishmania enriettii and correlation with macrophage oxidative metabolism
11. Modulation of macrophage function by transforming growth factor-β, interleukin 4 and intedeukin 10
12. Cytokine interactions in experimental cutaneous leishmaniasis. II. Endogenous tumor necrosis factor α production by macrophages is induced by the synergistic action of interferon (IFN) γ and interleukin (IL) 4 and accounts for the antiparasitic effect mediated by IFN-γ and IL-4
13. Leishmania major: Infection of human monocytes induces expression of IL-8 and MCAF
14. Leishmania major: Promastigotes induce expression of a subset of chemokine genes in murine macrophages
15. Leishmania promastigotes selectively inhibit interleukin 12 induction in bone marrow-derived macrophages from susceptible and resistant mice
16. Leishmania donovani infection initiates T cell-independent chemokine responses, which are subsequently amplified in a T cell-dependent manner
17. Immunologic responsiveness in American cutaneous leishmaniasis lesions
18. + T cells during a pulmonary Cryptococcus neoformans infection
19. Local production of chemokines during experimental vaginal candidiasis
20. β chemokines enhance parasite uptake and promote nitric oxide-dependent microbiostatic activity in murine inflammatory macrophages infected with Trypanosoma cruzi
21. 2+ and intracellular acidification
22. Nitric oxide in leishmaniasis
23. Inducible nitric oxide synthase in human diseases
24. 2+ mobilization, and enzyme release
25. Early gene expression of NK cell-activating chemokines in mice resistant to Leishmania major
26. Selective inhibition of expression of the chemokine receptor CCR2 in human monocytes by IFN-γ
27. Expression of a monocyte chemotactic cytokine by human mononuclear phagocytes
28. Role of monocyte chemoattractant protein-1 (MCP-1) in Th1 (mycobacterial) and Th2 (schistosomal) antigen-induced granuloma formation
29. Antigen-pulsed epidermal Langerhans cells protect susceptible mice from infection with the intracellular parasite Leishmania major
30. A quickeasy and inexpensive method for the isolation of human peripheral blood monocytes
31. Parasitism of epidermal Langerhans cells in experimental cutaneous leishmaniasis with Leishmania major
32. Involvement of reactive oxygen metabolites in the candidacidal activity of human neutrophils stimulated by muramyl dipeptide or tumor necrosis factor
33. Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids
34. Nitric oxide synthase: mRNA expression of different isoforms in human monocytes/macrophages
35. A new monoclonal antibody (5D3-F7) which recognizes human monocyte-chemotactic protein-1 but not related chemokines. Development of a sandwich ELISA and in situ detection of producing cells
36. Selective induction of monocyte and not neutrophil-attracting chemokines after influenza A virus infection