Nicotinamide exacerbates hypoxemia in ventilator-induced lung injury independent of neutrophil infiltration

PLoS ONE

Volumn 10, Issue 4, 2015, Pages

  Jones, Heather D ^a   Yoo, Jeena ^a   Crother, Timothy R ^a   Kyme, Pierre ^a   Ben Shlomo, Anat ^a   Khalafi, Ramtin ^a   Tseng, Ching W ^a   Parks, William C ^a   Arditi, Moshe ^a   Liu, George Y ^a   Shimada, Kenichi ^a  

^a CEDARS SINAI MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN EPSILON; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; INTERLEUKIN 6; KERATINOCYTE DERIVED CHEMOKINE; MACROPHAGE INFLAMMATORY PROTEIN 2; NICOTINAMIDE; NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE; NITRIC OXIDE; SIRTUIN 1; TUMOR NECROSIS FACTOR ALPHA; ANTIINFLAMMATORY AGENT; CCAAT ENHANCER BINDING PROTEIN; CEBPE PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CEBPA GENE; CEBPB GENE; CEBPE GENE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVITY; GENE; GENE EXPRESSION; HYPOXEMIA; LUNG LAVAGE; MALE; MECHANICAL VENTILATOR; MOUSE; NEUTROPHIL CHEMOTAXIS; NEUTROPHIL COUNT; NONHUMAN; NOS2 GENE; OXYGEN SATURATION; PROTEIN DETERMINATION; PROTEIN EXPRESSION; SIRT1 GENE; VENTILATOR INDUCED LUNG INJURY; 129 MOUSE; ANIMAL; C57BL MOUSE; CHEMICALLY INDUCED; DRUG EFFECTS; FEMALE; GENETICS; HYPOXIA; PATHOLOGY; VENTILATOR-INDUCED LUNG INJURY;

MUS;

ANIMALS; ANTI-INFLAMMATORY AGENTS; BRONCHOALVEOLAR LAVAGE; CCAAT-ENHANCER-BINDING PROTEINS; FEMALE; HYPOXIA; MALE; MICE; MICE, 129 STRAIN; MICE, INBRED C57BL; NEUTROPHIL INFILTRATION; NIACINAMIDE; VENTILATOR-INDUCED LUNG INJURY;

EID: 84929492227     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0123460     Document Type: Article

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