The bovine lung in biomedical research: Visually guided bronchoscopy, intrabronchial inoculation and in vivo sampling techniques

Journal of Visualized Experiments

Volumn , Issue 89, 2014, Pages

  Prohl, Annette ^a   Ostermann, Carola ^a   Lohr, Markus ^a   Reinhold, Petra ^a  

^a FEDERAL RESEARCH INSTITUTE FOR ANIMAL HEALTH   (Germany)

Author keywords

Bovine lung; Bronchial brushing; Bronchoalveolar lavage; Bronchoscopy; Cytology brush; Issue 89; Medicine; Respiratory models; Transbronchial lung biopsy; Translational medicine

Indexed keywords

EID: 84929481987     PISSN: 1940087X     EISSN: None     Source Type: Journal    
DOI: 10.3791/51557     Document Type: Article

References (55)

1. Ireland, J. J., Roberts, R. M., Palmer, G. H., Bauman, D. E., & Bazer, F. W. A commentary on domestic animals as dual-purpose models that benefit agricultural and biomedical research. Journal of animal science. 86, 2797-2805, doi:10.2527/jas.2008-1088 (2008).
2. Persson, C. G. Con: mice are not a good model of human airway disease. American journal of respiratory and critical care medicine. 166, 6-7,; discussion 8, doi:10.1164/rccm.2204001 (2002).
3. Haley, P. J. Species differences in the structure and function of the immune system. Toxicology. 188, 49-71 (2003).
4. Hein, W. R., & Griebel, P. J. A road less travelled: large animal models in immunological research. Nature reviews. Immunology. 3, 79-84, doi:10.1038/nri977 (2003).
5. Mestas, J., & Hughes, C. C. Of mice and not men: differences between mouse and human immunology. J Immunol. 172, 2731-2738 (2004).
6. Elferink, R. O., & Beuers, U. Are pigs more human than mice? Journal of hepatology. 50, 838-841, doi:10.1016/j.jhep.2008.12.014 (2009).
7. Jawien, J., & Korbut, R. The current view on the role of leukotrienes in atherogenesis. Journal of physiology and pharmacology: an official journal of the Polish Physiological Society. 61, 647-650 (2010).
8. Seok, J. et al. Genomic responses in mouse models poorly mimic human inflammatory diseases. Proceedings of the National Academy of Sciences of the United States of America. 110, 3507-3512, doi:10.1073/pnas.1222878110 (2013).
9. Pabst, R. in Allergy and Allergic Diseases. Vol. Volume 1 eds A. B. Kay, A. P. Kaplan, J. Bousquet, & P. G. Holt) Wiley-Blackwell, (2009).
10. Bovine Genome, S. et al. The genome sequence of taurine cattle: a window to ruminant biology and evolution. Science. 324, 522-528, doi:10.1126/science.1169588 (2009).
11. Tellam, R. L. et al. Unlocking the bovine genome. BMC genomics. 10, 193, doi:10.1186/1471-2164-10-193 (2009).
12. Graphodatsky, A. S., Trifonov, V. A., & Stanyon, R. The genome diversity and karyotype evolution of mammals. Molecular cytogenetics. 4, 22, doi:10.1186/1755-8166-4-22 (2011).
13. Kirschvink, N., & Reinhold, P. Use of alternative animals as asthma models. Current drug targets. 9, 470-484 (2008).
14. Coleman, R. A. Of mouse and man--what is the value of the mouse in predicting gene expression in humans? Drug discovery today. 8, 233-235 (2003).
15. Kips, J. C. et al. Murine models of asthma. The European respiratory journal, 22, 374-382 (2003).
16. Coraux, C., Hajj, R., Lesimple, P., & Puchelle, E. In vivo models of human airway epithelium repair and regeneration. European Respiratory Review. 14, 131-136, doi:10.1183/09059180.05.00009702 (2005).
17. McLaughlin, R. F., Tyler, W. S., & Canada, R. O. A Study of the Subgross Pulmonary Anatomy in Various Mammals. American Journal of Anatomy., 149-165 (1961).
18. Robinson, N. E. Some functional consequences of species differences in lung anatomy. Adv Vet Sci Comp Med. 26, 1-33 (1982).
19. Lekeux, P., Hajer, R., & Breukink, H. J. Effect of Somatic Growth on Pulmonary-Function Values in Healthy Friesian Cattle. Am J Vet Res. 45, 2003-2007 (1984).
20. Veit, H. P., & Farrell, R. L. The anatomy and physiology of the bovine respiratory system relating to pulmonary disease. Cornell Vet. 68, 555-581 (1978).
21. Gallivan, G. J., McDonell, W. N., & Forrest, J. B. Comparative pulmonary mechanics in the horse and the cow. Res Vet Sci. 46, 322-330 (1989).
22. Hunter, K. S. et al. In vivo measurement of proximal pulmonary artery elastic modulus in the neonatal calf model of pulmonary hypertension: development and ex vivo validation. Journal of applied physiology. 108, 968-975, doi:10.1152/japplphysiol.01173.2009 (2010).
23. Stenmark, K. R. et al. Severe pulmonary hypertension and arterial adventitial changes in newborn calves at 4,300 m. Journal of applied physiology. 62, 821-830 (1987).
24. Tian, L. et al. Impact of residual stretch and remodeling on collagen engagement in healthy and pulmonary hypertensive calf pulmonary arteries at physiological pressures. Annals of biomedical engineering. 40, 1419-1433, doi:10.1007/s10439-012-0509-4 (2012).
25. Van Rhijn, I., Godfroid, J., Michel, A., & Rutten, V. Bovine tuberculosis as a model for human tuberculosis: advantages over small animal models. Microbes and infection/Institut Pasteur. 10, 711-715, doi:10.1016/j.micinf.2008.04.005 (2008).
26. Otto, P. et al. A model for respiratory syncytial virus (RSV) infection based on experimental aerosol exposure with bovine RSV in calves. Comparative immunology, microbiology and infectious diseases. 19, 85-97 (1996).
27. Gershwin, L. J. et al. A bovine model of vaccine enhanced respiratory syncytial virus pathophysiology. Vaccine. 16, 1225-1236 (1998).
28. Gershwin, L. J. Immunology of bovine respiratory syncytial virus infection of cattle. Comparative immunology, microbiology and infectious diseases. 35, 253-257, doi:10.1016/j.cimid.2012.01.005 (2012).
29. Jaeger, J., Liebler-Tenorio, E., Kirschvink, N., Sachse, K., & Reinhold, P. A clinically silent respiratory infection with Chlamydophila spp. in calves is associated with airway obstruction and pulmonary inflammation. Veterinary research. 38, 711-728, doi:10.1051/vetres:2007027 (2007).
30. Martinez-Olondris, P., Rigol, M., & Torres, A. What lessons have been learnt from animal models of MRSA in the lung? The European respiratory journal. 35, 198-201, doi:10.1183/09031936.00113908 (2010).
31. Sadowitz, B., Roy, S., Gatto, L. A., Habashi, N., & Nieman, G. Lung injury induced by sepsis: lessons learned from large animal models and future directions for treatment. Expert review of anti-infective therapy. 9, 1169-1178, doi:10.1586/eri.11.141 (2011).
32. Ostermann, C. et al. Infection, Disease, and Transmission Dynamics in Calves after Experimental and Natural Challenge with a Bovine Chlamydia psittaci Isolate. PloS one. 8, e64066, doi:10.1371/journal.pone.0064066 (2013).
33. Ostermann, C., Schroedl, W., Schubert, E., Sachse, K., & Reinhold, P. Dose-dependent effects of Chlamydia psittaci infection on pulmonary gas exchange, innate immunity and acute-phase reaction in a bovine respiratory model. Vet J. 196, doi:10.1016/j.tvjl.2012.10.035 (2012).
34. Reinhold, P. et al. A bovine model of respiratory Chlamydia psittaci infection: challenge dose titration. PloS one. 7, e30125, doi:10.1371/journal.pone.0030125 (2012).
35. Reinhold, P., Sachse, K., & Kaltenboeck, B. Chlamydiaceae in cattle: commensals, trigger organisms, or pathogens? Vet J. 189, 257-267, doi:10.1016/j.tvjl.2010.09.003 (2011).
36. Dionisio, J. Diagnostic flexible bronchoscopy and accessory techniques. Revista portuguesa de pneumologia. 18, 99-106, doi:10.1016/j.rppneu.2012.01.003 (2012).
37. Hilding, A. C. Experimental bronchoscopy: resultant trauma to tracheobronchial epithelium in calves from routine inspection. Trans Am Acad Ophthalmol Otolaryngol. 72, 604-612 (1968).
38. Potgieter, M. M., Hopkins, F.M., Walker, R.D., Guy, J.S. Use of fiberoptic bronchoscopy in experimental production of bovine respiratory tract disease. Am J Vet Res. 45, 1015-1019 (1984).
39. Ackermann, M. R., Kehrli, M. E., Jr., & Brogden, K. A. Passage of CD18- and CD18+ bovine neutrophils into pulmonary alveoli during acute Pasteurella haemolytica pneumonia. Veterinary pathology. 33, 639-646 (1996).
40. Malazdrewich, C., Ames, T. R., Abrahamsen, M. S., & Maheswaran, S. K. Pulmonary expression of tumor necrosis factor alpha, interleukin-1 beta, and interleukin-8 in the acute phase of bovine pneumonic pasteurellosis. Veterinary pathology. 38, 297-310 (2001).
41. Wells, A. U. The clinical utility of bronchoalveolar lavage in diffuse parenchymal lung disease. European respiratory review: an official journal of the European Respiratory Society. 19, 237-241, doi:10.1183/09059180.00005510 (2010).
42. Wilkie, M. R. Sequential titration of bovine lung and serum antibodies after parenteral or pulmonary inoculation with Pasteurella haemolytica.Am J Vet Res. 40, 1690-1693 (1979).
43. Pringle, J. K. et al. Bronchoalveolar lavage of cranial and caudal lung regions in selected normal calves: cellular, microbiological, immunoglobulin, serological and histological variables. Canadian journal of veterinary research = Revue canadienne de recherche veterinaire. 52, 239-248 (1988).
44. Silflow, R. M., Degel, P. M., & Harmsen, A. G. Bronchoalveolar immune defense in cattle exposed to primary and secondary challenge with bovine viral diarrhea virus. Veterinary immunology and immunopathology. 103, 129-139, doi:10.1016/j.vetimm.2004.09.008 (2005).
45. Mitchell, G. B., Clark, M. E., & Caswell, J. L. Alterations in the bovine bronchoalveolar lavage proteome induced by dexamethasone. Veterinary immunology and immunopathology. 118, 283-293, doi:10.1016/j.vetimm.2007.05.017 (2007).
46. Mitchell, G. B., Clark, M. E., Siwicky, M., & Caswell, J. L. Stress alters the cellular and proteomic compartments of bovine bronchoalveolar lavage fluid. Veterinary immunology and immunopathology. 125, 111-125, doi:10.1016/j.vetimm.2008.05.005 (2008).
47. Lordan, J. L. et al. Cooperative effects of Th2 cytokines and allergen on normal and asthmatic bronchial epithelial cells. J Immunol. 169, 407-414 (2002).
48. Tukey, M. H., & Wiener, R. S. Population-based estimates of transbronchial lung biopsy utilization and complications. Respiratory medicine. 106, 1559-1565, doi:10.1016/j.rmed.2012.08.008 (2012).
49. Braun, U., Estermann, U., Feige, K., Sydler, T., & Pospischil, A. Percutaneous lung biopsy in cattle. Journal of the American Veterinary Medical Association. 215, 679-681 (1999).
50. Burgess, B. A. et al. The development of a novel percutaneous lung biopsy procedure for use on feedlot steers. Canadian journal of veterinary research = Revue canadienne de recherche veterinaire. 75, 254-260 (2011).
51. Sydler, T., Braun, U., Estermann, U., & Pospischil, A. A comparison of biopsy and post-mortem findings in the lungs of healthy cows. Journal of veterinary medicine. A, Physiology, pathology, clinical medicine. 51, 184-187, doi:10.1111/j.1439-0442.2004.00625.x (2004).
52. Voigt, K. et al. PCR examination of bronchoalveolar lavage samples is a useful tool in pre-clinical diagnosis of ovine pulmonary adenocarcinoma (Jaagsiekte). Research in Veterinary Science. 83, 419-427 (2007).
53. Caldow, G. Bronchoalveolar lavage in the investigation of bovine respiratory disease. In Practice. 1, 41-43 (2001).
54. Heilmann, P., Müller, G., & Reinhold, P. [Bronchoscopy and Segmental Bronchoalveolar Lung Lavage of Anesthetised Calf]. Monatsh. Veterinärmed. 43, 79-84 (1988).
55. Gogolewski, R. P. et al. Protective ability and specificity of convalescent serum from calves with Haemophilus somnus pneumonia. Infection and immunity. 55, 1403-1411 (1987).