A clinically silent respiratory infection with Chlamydophila spp. in calves is associated with airway obstruction and pulmonary inflammation

Veterinary Research

Volumn 38, Issue 5, 2007, Pages 711-728

  Jaeger, Julia ^a,b   Liebler Tenorio, Elisabeth ^a   Kirschvink, Nathalie ^c   Sachse, Konrad ^a   Reinhold, Petra ^a  

^a FEDERAL RESEARCH INSTITUTE FOR ANIMAL HEALTH   (Germany)

^b UNIVERSITY OF LEIPZIG   (Germany)

^c UNIVERSITY OF NAMUR   (Belgium)

Author keywords

Airway obstruction; Calves; Chlamydia; Chlamydophila infection; Pulmonary inflammation

Indexed keywords

8 ISOPROSTANE; DNA; GELATINASE A; PROTEIN;

AIRWAY OBSTRUCTION; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTOPSY; BACTERIAL INFECTION; BRONCHUS OBSTRUCTION; CALF (BOVINE); CHLAMYDOPHILA; CHLAMYDOPHILA ABORTUS; CHLAMYDOPHILA PECORUM; CLINICAL FEATURE; CONTROLLED STUDY; DNA DETERMINATION; ENZYME ACTIVITY; EX VIVO STUDY; FEMALE; INFECTION RATE; LUNG FUNCTION TEST; LUNG INFILTRATE; LUNG INTERSTITIUM; LUNG LAVAGE; LUNG LOBE; LUNG MINUTE VOLUME; LUNG VENTILATION; MALE; NON INVASIVE MEASUREMENT; NONHUMAN; OSCILLOMETRY; PERSISTENT INFECTION; PROTEIN BLOOD LEVEL; REAL TIME POLYMERASE CHAIN REACTION;

AIRWAY OBSTRUCTION; AIRWAY RESISTANCE; ANIMALS; ANIMALS, NEWBORN; BRONCHOALVEOLAR LAVAGE FLUID; CATTLE; CATTLE DISEASES; CHLAMYDOPHILA; CHLAMYDOPHILA INFECTIONS; FEMALE; LUNG; MALE; MATRIX METALLOPROTEINASES; PNEUMONIA; POLYMERASE CHAIN REACTION; PROSPECTIVE STUDIES; RESPIRATORY FUNCTION TESTS; RESPIRATORY MECHANICS;

ANIMALIA; CHLAMYDIA; CHLAMYDOPHILA; CHLAMYDOPHILA ABORTUS; CHLAMYDOPHILA PECORUM;

EID: 35748954032     PISSN: 09284249     EISSN: 12979716     Source Type: Journal    
DOI: 10.1051/vetres:2007027     Document Type: Article

References (56)

1. Anderson M.L., Moore P.F., Hyde D.M., Dungworth D.L., Bronchus associated lymphoid tissue in the lungs of cattle: relationship to age, Res. Vet. Sci. (1986) 41:211-220.
2. Blasi F., Atypical pathogens and respiratory tract infections, Eur. Respir. J. (2004) 24:171-181.
3. Branden E., Koyi H., Gnarpe J., Gnarpe H., Tornling G., Chronic Chlamydia pneumoniae infection is a risk factor for the development of COPD, Respir. Med. (2005) 99:20-26.
4. Castleman W.L., Lay J.C., Morphometric and ultrastructural study of postnatal lung growth and development in calves, Am. J. Vet. Res. (1990) 51:789-795.
5. Ehricht R., Slickers P., Goellner S., Hotzel H., Sachse K., Optimized DNA microarray assay allows detection and genotyping of single PCR-amplifiable target copies, Mol. Cell. Probes (2006) 20:60-63.
6. Esposito S., Blasi F., Bellini F., Allegra L., Principi N., and the Mowgli Study Group, Mycoplasma pneumoniae and Chlamydia pneumoniae infections in children with pneumonia, Eur. Respir. J. (2001) 17:241-245.
7. Goellner S., Schubert E., Liebler-Tenorio E., Hotzel H., Saluz H.P., Sachse K., Transcriptional response patterns of Chlamydophila psittaci in different in vitro models of persistent infection, Infect. Immun. (2006) 74:4801-4808.
8. Grayston J.T., Campbell L.A., Kuo C.C., Mordhorst C.H., Saikku P., Thom D.H., Wang S.P., A new respiratory tract pathogen: Chlamydia pneumoniae strain TWAR, J. Infect. Dis. (1990) 161:618-625.
9. Haas L.E., Tjan D.H., Schouten M.A., van Zanten A.R., Severe pneumonia from psittacosis in a bird-keeper, Ned. Tijdschr. Geneeskd. (2006) 150:117-121.
10. Hammerschlag M.R., Chlamydia pneumoniae and the lung, Eur. Respir. J. (2000) 16:1001-1007.
11. Hogan R.J., Mathews S.A., Mukhopadhyay S., Summersgill J.T., Timms P., Chlamydial persistence: beyond the biphasic paradigm, Infect. Immun. (2004) 74:1843-1855.
12. Janssen M.L., van de Wetering K., Arabin B., Sepsis due to gestational psittacosis: A multidisciplinary approach within a perinatological center - review of reported cases, Int. J. Fertil. Womens Med. (2006) 51:17-20.
13. Jee J., DeGraves F.J., Kim T., Kaltenboeck B., High prevalence of natural Chlamydophila spp. infection in calves, J. Clin. Microbiol. (2004) 42:5664-5672.
14. Johnston S.L., Martin R.J., Chlamydophila pneumoniae and Mycoplasma pneumoniae - A role in asthma pathogenesis? Am. J. Respir. Crit. Care Med. (2005) 172:1078-1089.
15. Kirschvink N., Vincke G., Fievez L., Onclinx C., Wirth D., Cataldo D., Louis R., Peck M., Gustin P., Repeated cadmium nebulizations induce pulmonary MMP-2 and MMP-9 production and emphysema in rats, Toxicology (2005) 211:36-48.
16. Lakritz J., Marsh A., Cockrell M., Smith M.F., Tyler J.W., Characterization of gelatinases in bronchoalveolar labage fluid and gelatinases produced by alveolar macrophages isolated from healthy calves, Am. J. Vet. Res. (2004) 65:163-172.
17. Lekeux P., Hajer R., Breukink H.J., Effect of somatic growth on pulmonary function values in healthy Friesian cattle, Am. J. Vet. Res. (1984) 45:2003-2007.
18. Lekeux P., Pulmonary function in healthy, exercising and diseased animals. Vlaams Diergegeneeskunding Tijdschrift 1993, Universiteit Gent, Belgium, special issue, 1993.
19. Littman A.J., Jackson L.A., Vaughan T.L., Chlamydia pneumoniae and lung cancer: epidemiologic evidence, Cancer Epidemiol. Biomarkers Prev. (2005) 14:773-778.
20. Livingstone M., Longbottom D., What is the prevalence and economic impact of chlamydial infections in cattle? The need to validate and harmonise existing methods of detection, Vet. J. (2006) 172:3-5.
21. Marrie T.J., Peeling R.W., Reid T., De Carolis E., and the Canadian Community-Acquired Pneumonia Investigators, Chlamydia species as a cause of community-acquired pneumonia in Canada, Eur. Respir. J. (2003) 21:779-784.
22. Martin R.J., Infections and asthma, Clin. Chest Med. (2006) 27:87-98.
23. Mead J., Mechanical properties of the lung, Physiol. Rev. (1961) 41:281-329.
24. Mitzner W., Collateral ventilation, in: Crystal R.G., West J.B., et al. (Eds.), The Lung, Scientific Foundations, Raven Press, New York, 1991, pp. 1053-1063.
25. Mpiga P., Ravaoarinoro M., Chlamydia trachomatis persistence: an update, Microbiol. Res. (2006) 161:9-19.
26. Normann E., Gnarpe J., Wettergren B., Janson C., Wickman M., Nordvall L., The association between Chlamydia pneumoniae antibodies and wheezing in young children and the influence of sex, Thorax (2006) 61:1054-1058.
27. Otter A., Twomey D.F., Rowe N.S., Tipp J.W., McElligott W.S., Griffiths P.C., O'Neill P., Suspected chlamydial keratoconjunctivitis in British cattle, Vet. Rec. (2003) 152:787-788.
28. Pandeli V., Ernest D., A case of fulminant psittacosis, Crit. Care Resusc. (2006) 8:40-42.
29. Reinhold P., MacLeod D., Lekeux P., Comparative evaluation of impulse oscillometry and a monofrequency forced oscillation technique in clinically healthy calves undergoing bronchochallenges, Res. Vet. Sci. (1996) 61:206-213.
30. Reinhold P., Smith H.-J., Langenberg A., Lekeux P., Measurement of respiratory impedance in healthy calves using the impulse oscillation technique - physiological and methodological aspects, Vet. J. (1998) 155:27-38.
31. Reinhold P., Smith H.-J., Close R., Genicot B., Lekeux P., Validation of impulse oscillometry in Friesian and Blue Belgian Calves with respect to changes in extrathoracic upper airway resistance, Res. Vet. Sci. (1998) 65:93-102.
32. Reinhold P., Jaeger J., Melzer F., Sachse K., Evaluation of lung function in pigs either experimentally or naturally infected with Chlamydiaceae, Vet. Res. Commun. (2005) (Suppl.1) 29:125-150.
33. Reinhold P., Jaeger J., Liebler-Tenorio E., Berndt A., Bachmann R., Schubert E., Melzer F., Elschner M., Sachse K., Impact of latent infections with Chlamydophila species in young cattle, Vet. J. (2007) in press, doi: 10.1016/j.tvjl.2007.01.004 (E-pub).
34. Robinson N.E., Some functional consequences of species differences in lung anatomy, Adv. Vet. Sci. Comp. Med. (1982) 26:1-33.
35. Rödel J., Prochnau D., Prager K., Pentcheva E., Hartmann M., Straube E., Increased production of matrix metalloproteinases 1 and 3 by smooth muscle cells upon infection with Chlamydia pneumoniae, FEMS Immunol. Med. Microbiol. (2003) 38:159-164.
36. Sachse K., Hotzel H., Detection and differentiation of chlamydiae by nested PCR, in: Sachse K., Frey J. (Eds.), PCR Detection of Microbial Pathogens, Humana Press, Totowa, NJ, USA, 2002, pp. 123-136.
37. Sachse K., Hotzel H., Slickers P., Ellinger T., Ehricht R., DNA microarray based detection and identification of Chlamydia and Chlamydophila, Mol. Cell. Probes (2005) 19:41-50.
38. Saikku P., The epidemiology and significance of Chlamydia pneumoniae, J. Infect. Dis. (1992) 25:27-34.
39. Schmidt S.M., Müller C.E., Bruns R., Wiersbitzky S.K.W., Bronchial Chlamydia pneumoniae infection, markers of allergic inflammation and lung function in children, Pediatr. Allergy Immunol. (2001) 12:257-265.
40. Schmidt S.M., Müller C.E., Krechting M., Wiersbitzky H., Gürtler L., Wiersbitzky S.K.W., Chlamydia pneumoniae carriage and infection in hospitalized children with respiratory tract diseases, Infection (2003) 31:410-416.
41. Schmidt S.M., Müller C.E., Wiersbitzky S.K.W., Inverse association between Chlamydia pneumoniae respiratory tract infection and initiation of asthma or allergic rhinitis in children, Pediatr. Allergy Immunol. (2005) 16:137-144.
42. Schmidt S.M., Müller C.E., Gürtler L., Bruns R., Ballke E.H., Wiersbitzky H., Ehlers M., Rose H.J., Wiersbitzky S.K.W., Chlamydophila pneumoniae respiratory tract infection aggravates therapy refractory bronchitis or pneumonia in childhood, Klin. Pädiatr. (2005) 217:9-14.
43. Shemer-Avni Y., Liebermann D., Chlamydia pneumoniae-induced ciliostasis in ciliated bronchial epithelial cells, J. Infect. Dis. (1995) 171:1274-1278.
44. Simonen-Jokinen T.L.M., Eskelinen U.M., Härtel H.M., Nikunen S.K., Saloniemi H.S., Maisi P.S., Gelatinolytic matrix metalloproteinases-2 and -9 in tracheobronchial lavage fluid obtained from calves with concurrent infections of Pasteurella multocida and Mycoplasma bovirhinis, Am. J. Vet. Res. (2005) 66:2101-2106.
45. Smith H.-J., Reinhold P., Goldman M.D., Forced oscillation technique and impulse oscillometry, Eur. Respir. Monogr. (2005) 31:72-105.
46. Stephens R.S., The cellular paradigm of chlamydial pathogenesis, Trends Microbiol. (2003) 11:44-51.
47. Storz J., Kaltenboeck B., Diversity of chlamydia-induced diseases, in: Woldehiwet Z., Ristic M. (Eds.), Rickettsial and chlamydial diseases of domestic animals, Pergamon Press, Oxford/UK, 1993, pp. 363-393.
48. Suzuki R., Miyazaki Y., Takagi K., Torii K., Taniguchi H., Matrix metalloproteinases in the pathogenesis of asthma and COPD: implications for therapy, Treat. Respir. Med. (2004) 3:17-27.
49. ten Brinke A., van Dissel J.T., Sterk P.J., Zwinderman A.H., Rabe K.F., Bel E.H., Persistent airflow limitation in adult-onset nonatopic asthma is associated with serologic evidence of Chlamydia pneumoniae infection, J. Allergy Clin. Immunol. (2001) 107:449-454.
50. Theegarten D., Mogilevski G., Anhenn O., Stamatis G., Jaeschock R., Morgenroth K., The role of Chlamydia in the pathogenesis of pulmonary emphysema. Electron microscopy and immunofluorescence reveal corresponding findings as in atherosclerosis, Virchows Arch. (2000) 437:190-193.
51. Theegarten D., Anhenn O., Hotzel H., Wagner M., Marra A., Stamatis G., Mogilevski G., Sachse K., A comparative ultrastructural and molecular biological study on Chlamydia psittaci infection in alpha-1 antitrypsin deficiency and nonalpha-1 antitrypsin deficiency emphysema versus lung tissue of patients with hamartochondroma, BMC Infect. Dis. (2004) 4:38.
52. Twomey D.F., Griffiths P.C., Hignett B.C., Martin T.P., Suspected chlamydial polyarthritis in a calf in the UK, Vet. Rec. (2003) 152:340.
53. Twomey D.F., Griffiths P.C., Horigan M.W., Hignett B.C., Martin T.P., An investigation into the role of Chlamydophila spp. in bovine upper respiratory tract disease, Vet. J. (2006) 171:574-576.
54. Walder G., Schonherr H., Hotzel H., Speth C., Oehme A., Dierich M.P., Wurzner R., Presence of Chlamydophila psittaci DNA in the central nervous system of a patient with status epilepticus, Scand. J. Infect. Dis. (2003) 35:71-73.
55. Walder G., Hotzel H., Brezinka C., Gritsch W., Tauber R., Wurzner R., Ploner F., An unusual cause of sepsis during pregnancy: recognizing infection with Chlamydophila abortus, Obstet. Gynecol. (2005) 106:1215-1217.
56. Webley W.C., Salva P.S., Andrzejewski C., Cirino F., West C.A., Tilahun Y., Stuart E.S., The bronchial lavage of pediatric patients with asthma contains infectious Chlamydia, Am. J. Respir. Crit. Care Med. (2005) 171:1083-1088.