In vivo models of human airway epithelium repair and regeneration

European Respiratory Review

Volumn 14, Issue 97, 2005, Pages 131-136

  Coraux, C ^a   Hajj, R ^a   Lesimple, P ^a   Puchelle, E ^a  

^a HÔPITAL MAISON BLANCHE   (France)

Author keywords

Airway epithelium; Humanised xenografts; Nude mice; Severe combined immunodeficient mice; Stem and progenitor cells

Indexed keywords

GELATINASE B; INTERLEUKIN 8; MATRILYSIN; MATRIX METALLOPROTEINASE;

BASEMENT MEMBRANE; CELL DIFFERENTIATION; CELL MIGRATION; CELL REGENERATION; CELL SPREADING; EPITHELIUM CELL; EXPERIMENTAL MODEL; HUMAN; IMMUNE DEFICIENCY; IN VIVO STUDY; NONHUMAN; NUDE MOUSE; RESPIRATORY EPITHELIUM; RESPIRATORY TRACT DISEASE; REVIEW; SCID MOUSE; XENOGRAFT;

EID: 33747595635     PISSN: 09059180     EISSN: None     Source Type: Journal    
DOI: 10.1183/09059180.05.00009702     Document Type: Review

References (24)

1. Puchelle E, de Bentzmann S, Jacquot J, Zahm JM. Defense properties of airway surface liquid. In: Gibson GJ, Gedded DM Costabel U, Sterk P, Corrin B, eds. Respiratory Medicine. Philadelphia, PA, USA, Saunders, 2003; pp. 194-204.
2. Bals R, Weiner DJ, Wilson JM. The innate immune system in cystic fibrosis lung disease. J Clin Invest 1999; 103: 303-307.
3. Puchelle E, Zahm JM, Tournier JM, de Bentzmann S. Airway epithelial injury and repair. Eur Respir Res 1997; 43: 136-141.
4. Man SFP, Hulbert WC. Airway repair and adaptation to inhalation injury. In: Loke J, ed. Pathophysiology and Treatment of Inhalation Injuries. Lung Biology in Health and Disease. New York, NY, USA, Dekker, 1988; pp. 1-47.
5. Puchelle E, Peault B. Human airway xenograft models of epithelial cell regeneration. Respir Res 2000; 1: 125-128.
6. Puchelle E, Zahm JM. Repair process of the airway epithelium. In: Chretien J, Dusser D, eds. Environmental Impact on the Airways. From Injury to Repair. New York, NY, USA, Dekker, 1996; pp. 157-182.
7. Puchelle E. Airway epithelium wound repair and regeneration after injury. Acta Otorhinolaryngol Belg 2000; 54: 263-270.
8. McDowell EM, Becci PJ, Schurch W, Trump BF. The respiratory epithelium. VII. Epidermoid metaplasia of hamster tracheal epithelium during regeneration following mechanical injury. J Natl Cancer Inst 1979; 62: 995-1008.
9. Hong KU, Reynolds SD, Giangreco A, Hurley CM, Stripp BR. Clara cell secretory protein-expressing cells of the airway neuroepithelial body microenvironment include a label-retaining subset and are critical for epithelial renewal after progenitor cell depletion. Am J Respir Cell Mol Biol 2001; 24: 671-681.
10. Hong KU, Reynolds SD, Watkins S, Fuchs E, Stripp BR. Basal cells are a multipotent progenitor capable of renewing the bronchial epithelium. Am J Pathol 2004; 164: 577-588.
11. Borthwick DW, Shahbazian M, Todd Krantz Q, Dorin J, Randell SH. Evidence for stem-cell niches in the tracheal epithelium. Am J Respir Cell Mol Biol 2001; 24: 662-670.
12. Shimizu T, Nettesheim P, Ramaekers FC, Randell SH. Expression of "cell-type-specific" markers during rat tracheal epithelial regeneration. Am J Respir Cell Mol Biol 1992; 7: 30-41.
13. Liu JY, Nettesheim P, Randell SH. Growth and differentiation of tracheal epithelial progenitor cells. Am J Physiol 1994; 266: L296-L307.
14. Engelhardt JF, Yankaskas JR, Wilson JM. In vivo retroviral gene transfer into human bronchial epithelia of xenografts. J Clin Invest 1992; 90: 2598-2607.
15. Zepeda ML, Chinoy MR, Wilson JM. Characterization of stem cells in human airway capable of reconstituting a fully differentiated bronchial epithelium. Somat Cell Mol Genet 1995; 21: 61-73.
16. Engelhardt JF, Schlossberg H, Yankaskas JR, Dudus L. Progenitor cells of the adult human airway involved in submucosal gland development. Development 1995; 121: 2031-2046.
17. Dupuit F, Gaillard D, Hinnrasky J, et al. Differentiated and functional human airway epithelium regeneration in tracheal xenografts. Am J Physiol Lung Cell Mol Physiol 2000; 278: L165-L176.
18. Escotte S, Catusse C, Coraux C, Puchelle E. Reconstitution of human airway tissue in the humanized xenograft model. J Cyst Fibros 2004; 3: Suppl. 2, 63-65.
19. Coraux C, Martinella-Catusse C, Nawrocki-Raby B, et al. Differential expression of matrix metalloproteinases and interleukin-8 during regeneration of human airway epithelium in vivo. J Pathol 2005; 206: 160-169.
20. Castillon N, Hinnrasky J, Zahm JM, et al. Polarized expression of cystic fibrosis transmembrane conductance regulator and associated epithelial proteins during the regeneration of human airway surface epithelium in three-dimensional culture. Lab Invest 2002; 82: 989-998.
21. Castillon N, Avril-Delplanque A, Coraux C, et al. Regeneration of a well-differentiated human airway surface epithelium by spheroid and lentivirus vector-transduced airway cells. J Gene Med 2004; 6: 846-856.
22. Peault B, Tirouvanziam R, Sombardier MN, Chen S, Perricaudet M, Gaillard D. Gene transfer to human fetal pulmonary tissue developed in immunodeficient SCID mice. Hum Gene Ther 1994; 5: 1131-1137.
23. Delplanque A, Coraux C, Tirouvanziam R, et al. Epithelial stem cell-mediated development of the human respiratory mucosa in SCID mice. J Cell Sci 2000; 113: 767-778.
24. Avril-Delplanque A, Casal I, Castillon N, Hinnrasky J, Puchelle E, Peault B. Aquaporin-3 expression in human fetal airway epithelial progenitor cells. Stem Cells 2005; 23: 992-1001.