Regulatory crosstalk between lineage-survival oncogenes KLF5, GATA4 and GATA6 cooperatively promotes gastric cancer development

Gut

Volumn 64, Issue 5, 2015, Pages 707-719

  Chia, Na Yu ^a   Deng, Niantao ^a,b   Das, Kakoli ^a   Huang, Dachuan ^c   Hu, Longyu ^a,d   Zhu, Yansong ^a   Lim, Kiat Hon ^e   Lee, Ming Hui ^c   Wu, Jeanie ^c   Sam, Xin Xiu ^e   Tan, Gek San ^e   Wan, Wei Keat ^e   Yu, Willie ^c   Gan, Anna ^c   Tan, Angie Lay Keng ^a   Tay, Su Ting ^a   Soo, Khee Chee ^c   Wong, Wai Keong ^e   Dominguez, Lourdes Trinidad M ^e   Ng, Huck Hui ^f   Rozen, Steve ^a   Goh, Liang Kee ^a,g   The, Bin Tean ^a,c   Tan, Patrick ^a,c,d,f   more..

^a DUKE NUS MEDICAL SCHOOL   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^c DIVISION OF MEDICAL ONCOLOGY   (Singapore)

^d NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^e SINGAPORE GENERAL HOSPITAL   (Singapore)

^f GENOME INSTITUTE OF SINGAPORE   (Singapore)

^g NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

HEPATOCYTE NUCLEAR FACTOR 4ALPHA; KRUPPEL LIKE FACTOR 5; MESSENGER RNA; METFORMIN; TRANSCRIPTION FACTOR GATA 4; TRANSCRIPTION FACTOR GATA 6; GATA4 PROTEIN, HUMAN; GATA6 PROTEIN, HUMAN; KLF5 PROTEIN, HUMAN; KRUPPEL LIKE FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING SITE; CANCER GROWTH; CANCER SURVIVAL; CHROMATIN IMMUNOPRECIPITATION; COHORT ANALYSIS; CONTROLLED STUDY; DNA SEQUENCE; DRUG TARGETING; GASTRIC CANCER CELL LINE; GENE AMPLIFICATION; GENE CONTROL; GENE DOSAGE; GENE EXPRESSION; GENE LOCATION; GENE TARGETING; GENOMICS; HNF4ALPHA GENE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; ONCOGENE; ONCOGENE GATA4; ONCOGENE GATA6; ONCOGENE KLF5; PHENOTYPE; PRIMARY TUMOR; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; STOMACH CANCER; STOMACH CARCINOGENESIS; TRANSCRIPTION REGULATION; TUMOR XENOGRAFT; VALIDATION STUDY; ANIMAL; BIOSYNTHESIS; CANCER TRANSPLANTATION; CELL PROLIFERATION; CELL TRANSFORMATION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE SILENCING; GENETIC PREDISPOSITION; GENETICS; METABOLISM; NUDE MOUSE; PATHOLOGY; PROCEDURES; STOMACH TUMOR; TUMOR CELL CULTURE; XENOGRAFT;

ANIMALS; CELL PROLIFERATION; CELL TRANSFORMATION, NEOPLASTIC; GATA4 TRANSCRIPTION FACTOR; GATA6 TRANSCRIPTION FACTOR; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE SILENCING; GENETIC PREDISPOSITION TO DISEASE; HETEROGRAFTS; HUMANS; KRUPPEL-LIKE TRANSCRIPTION FACTORS; MICE, NUDE; NEOPLASM TRANSPLANTATION; ONCOGENES; PROMOTER REGIONS, GENETIC; STOMACH NEOPLASMS; TUMOR CELLS, CULTURED;

EID: 84929466191     PISSN: 00175749     EISSN: 14683288     Source Type: Journal    
DOI: 10.1136/gutjnl-2013-306596     Document Type: Article

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