Dual miRNA Targeting Restricts Host Range and Attenuates Neurovirulence of Flaviviruses

PLoS Pathogens

Volumn 11, Issue 4, 2015, Pages

  Tsetsarkin, Konstantin A ^a   Liu, Guangping ^a   Kenney, Heather ^a   Bustos Arriaga, Jose ^a   Hanson, Christopher T ^a   Whitehead, Stephen S ^a   Pletnev, Alexander G ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LIVE VACCINE; MICRORNA; MICRORNA 124; MICRORNA 184; MICRORNA 275; UNCLASSIFIED DRUG; DENGUE VACCINE;

AEDES; ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DENGUE VIRUS 4; DISEASE TRANSMISSION; DNA TRANSFECTION; ELECTROPORATION; FEMALE; FLAVIVIRUS; GENE EXPRESSION; GENE SILENCING; GENE TARGETING; GENETIC ANALYSIS; GENETIC STABILITY; HOST RANGE; IMMUNOHISTOCHEMISTRY; MOUSE; NEUROLOGIC DISEASE; NONHUMAN; NORTHERN BLOTTING; OPEN READING FRAME; POLYMERASE CHAIN REACTION; VIRUS INFECTION; VIRUS REPLICATION; ANIMAL; DENGUE; DENGUE VIRUS; GENETIC TRANSFECTION; INSECT VECTOR; MOSQUITO; PATHOGENICITY; PHYSIOLOGY; VIROLOGY; VIRULENCE;

FLAVIVIRUS; VERTEBRATA;

ANIMALS; CULICIDAE; DENGUE; DENGUE VACCINES; DENGUE VIRUS; ELECTROPORATION; HOST SPECIFICITY; INSECT VECTORS; MICE; MICRORNAS; TRANSFECTION; VACCINES, ATTENUATED; VIRULENCE; VIRUS REPLICATION;

EID: 84929455090     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1004852     Document Type: Article

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