Nitric oxide and Brazilian propolis combined accelerates tissue repair by modulating cell migration, cytokine production and collagen deposition in experimental leishmaniasis

PLoS ONE

Volumn 10, Issue 5, 2015, Pages

  Miranda, Milena Menegazzo ^a   Panis, Carolina ^b   Cataneo, Allan Henrique Depieri ^a   Da Silva, Suelen Santos ^a   Kawakami, Natalia Yoshie ^a   Lopes, Luiz Gonzaga De França ^c   Morey, Alexandre Tadachi ^a   Yamauchi, Lucy Megumi ^a   Andrade, Célia Guadalupe Tardelli De Jesus ^d   Cecchini, Rubens ^a   Da Silva, Jean Jerley Nogueira ^e   Sforcin, José Maurício ^f   Conchon Costa, Ivete ^a   Pavanelli, Wander Rogério ^a  

^a STATE UNIVERSITY OF LONDRINA   (Brazil)

^b UNIVERSIDADE ESTADUAL DO OESTE DO PARANÁ   (Brazil)

^c FEDERAL UNIVERSITY OF CEARÁ   (Brazil)

^d Biological Sciences Center   (Brazil)

^e UNIVERSIDADE ESTADUAL DE RORAIMA   (Brazil)

^f SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

3 NITROTYROSINE; ALANINE AMINOTRANSFERASE; ANTILEISHMANIAL AGENT; ASPARTATE AMINOTRANSFERASE; CIS [RU (2,2' BIPYRIDINE) 2 IMIDAZOLE (NITRIC OXIDE)](PF 6) 3; CIS [RUTHENIUM (2,2' BIPYRIDINE) 2 IMIDAZOLE (NITRIC OXIDE)](PF 6) 3; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 10; MEGLUMINE ANTIMONATE; PROPOLIS; STAT3 PROTEIN; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; COLLAGEN; CYTOKINE; NITRIC OXIDE; NITRIC OXIDE DONOR;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APIS MELLIFERA; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL COUNT; CELL MIGRATION; COLLAGEN SYNTHESIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG EFFICACY; ENZYME ACTIVITY; FEMALE; FIBROBLAST; IMMUNOMODULATION; IN VIVO STUDY; LEISHMANIA MEXICANA; MOUSE; NONHUMAN; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SKIN DEFECT; SKIN LEISHMANIASIS; T LYMPHOCYTE SUBPOPULATION; UPREGULATION; WOUND HEALING; ANIMAL; BAGG ALBINO MOUSE; BIOSYNTHESIS; CELL MOTION; CHEMISTRY; COMBINATION DRUG THERAPY; DRUG EFFECTS; DRUG POTENTIATION; GROWTH, DEVELOPMENT AND AGING; HINDLIMB; INTRAPERITONEAL DRUG ADMINISTRATION; LEISHMANIA; LEISHMANIASIS, CUTANEOUS; MACROPHAGE; ORAL DRUG ADMINISTRATION; PARASITOLOGY; PATHOLOGY;

LEISHMANIA AMAZONENSIS; MUS;

ADMINISTRATION, ORAL; ANIMALS; CELL MOVEMENT; COLLAGEN; CYTOKINES; DRUG SYNERGISM; DRUG THERAPY, COMBINATION; FEMALE; FIBROBLASTS; HINDLIMB; INJECTIONS, INTRAPERITONEAL; LEISHMANIA; LEISHMANIASIS, CUTANEOUS; MACROPHAGES; MICE; MICE, INBRED BALB C; NITRIC OXIDE; NITRIC OXIDE DONORS; PROPOLIS; WOUND HEALING;

EID: 84929376809     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0125101     Document Type: Article

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