G-protein-coupled receptor kinase 2-mediated desensitization of adiponectin receptor 1 in failing heart

Circulation

Volumn 131, Issue 16, 2015, Pages 1392-1404

  Wang, Yajing ^a   Gao, Erhe ^b   Lau, Wayne Bond ^a   Wang, Yang ^a   Liu, Gaizheng ^a   Li, Jing Jing ^a   Wang, Xiaoliang ^a   Yuan, Yuexing ^a   Koch, Walter J ^b   Ma, Xin Liang ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Adipokines; Heart failure; Phosphorylation; Receptors, adiponectin

Indexed keywords

ADIPONECTIN; ADIPONECTIN RECEPTOR 1; ADIPONECTIN RECEPTOR 2; ENDOTHELIAL NITRIC OXIDE SYNTHASE; G PROTEIN COUPLED RECEPTOR KINASE 2; GLUCOSE TRANSPORTER 4; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; SERINE; THREONINE; ADIPONECTIN RECEPTOR; ADIPONECTIN RECEPTOR 1, MOUSE; ADIPONECTIN RECEPTOR 2, MOUSE; ADIPOR1 PROTEIN, HUMAN; ADRBK1 PROTEIN, MOUSE; HYBRID PROTEIN; SLC2A4 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY OCCLUSION; DESENSITIZATION; ENZYME ACTIVATION; EX VIVO STUDY; GENE OVEREXPRESSION; HEART FAILURE; HEART INFARCTION; HEART LEFT VENTRICLE EJECTION FRACTION; HEART MUSCLE CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; MASS SPECTROMETRY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; CELL CULTURE; COMPLICATION; DEFICIENCY; DRUG EFFECTS; ENZYMOLOGY; GENE THERAPY; GENE VECTOR; GENETIC TRANSDUCTION; GENETICS; KNOCKOUT MOUSE; METABOLISM; PATHOLOGY; PHOSPHORYLATION; PHYSIOLOGY; PROTEIN PROCESSING; THERAPEUTIC USE;

ADIPONECTIN; AMP-ACTIVATED PROTEIN KINASES; ANIMALS; CELLS, CULTURED; G-PROTEIN-COUPLED RECEPTOR KINASE 2; GENETIC THERAPY; GENETIC VECTORS; GLUCOSE TRANSPORTER TYPE 4; HEART FAILURE; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MYOCARDIAL INFARCTION; MYOCYTES, CARDIAC; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; RECEPTORS, ADIPONECTIN; RECOMBINANT FUSION PROTEINS; TRANSDUCTION, GENETIC;

EID: 84929320169     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.114.015248     Document Type: Article

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