Ammonium increases Ca2+ signalling and upregulates expression of Cav1.2 gene in astrocytes in primary cultures and in the in vivo brain

Acta Physiologica

Volumn 214, Issue 2, 2015, Pages 261-274

  Wang, F ^a   Du, T ^a   Liang, C ^a   Verkhratsky, A ^b,c,d   Peng, L ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

^c BASQUE FOUNDATION FOR SCIENCE   (Spain)

^d LOBACHEVSKY STATE UNIVERSITY OF NIZHNY NOVGOROD   (Russian Federation)

Author keywords

Ammonium; Astrocyte; Cav1.2 channels; Calcium signalling; Hepatic encephalopathy

Indexed keywords

AMMONIUM CHLORIDE; CALCIUM CHANNEL L TYPE; CALCIUM ION; CANRENONE; FURA 2; MESSENGER RNA; NIFEDIPINE; RYANODINE; UREASE; VOLTAGE GATED CALCIUM CHANNEL; AMMONIUM DERIVATIVE; CACNA1C PROTEIN, MOUSE; CALCIUM;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTROCYTE; CA V 1 2 GENE; CALCIUM SIGNALING; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOSOL; DEPOLARIZATION; FEMALE; FLUORESCENCE ACTIVATED CELL SORTING; GENE; GENE EXPRESSION; GENE SILENCING; HYPERAMMONEMIA; IN VIVO STUDY; LONG TERM CARE; MALE; MICROFLUOROMETRY; MOUSE; NONHUMAN; PRIMARY CULTURE; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSGENIC MOUSE; UPREGULATION; WESTERN BLOTTING; ANIMAL; BRAIN; CELL CULTURE; CYTOLOGY; DRUG EFFECTS; GENETICS; METABOLISM; TRANSCRIPTION INITIATION;

AMMONIUM COMPOUNDS; ANIMALS; ASTROCYTES; BRAIN; CALCIUM; CALCIUM CHANNELS, L-TYPE; CALCIUM SIGNALING; CELLS, CULTURED; FEMALE; MALE; MICE; MICE, TRANSGENIC; RYANODINE; TRANSCRIPTIONAL ACTIVATION; UP-REGULATION;

EID: 84929296155     PISSN: 17481708     EISSN: 17481716     Source Type: Journal    
DOI: 10.1111/apha.12500     Document Type: Article

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