High glutathione and glutathione peroxidase-2 levels mediate cell-type-specific DNA damage protection in human induced pluripotent stem cells

Stem Cell Reports

Volumn 4, Issue 5, 2015, Pages 886-898

  Dannenmann, Benjamin ^a   Lehle, Simon ^a   Hildebrand, Dominic G ^a   Kübler, Ayline ^a   Grondona, Paula ^a   Schmid, Vera ^a   Holzer, Katharina ^a   Fröschl, Mirjam ^a   Essmann, Frank ^a   Rothfuss, Oliver ^a   Schulze Osthoff, Klaus ^a,b  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CELL NUCLEUS DNA; GLUTATHIONE; GLUTATHIONE PEROXIDASE 2; MESSENGER RNA; MITOCHONDRIAL DNA; PROTEIN BCL 2; PROTEIN P53; ANTINEOPLASTIC AGENT; GLUTATHIONE PEROXIDASE; GPX2 PROTEIN, HUMAN; HYDROGEN PEROXIDE; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA;

APOPTOSIS; ARTICLE; CELL DEATH; CELL DIFFERENTIATION; DNA DAMAGE; FIBROBLAST; GENE EXPRESSION PROFILING; GENOME; GENOTOXICITY; HUMAN; HUMAN CELL; OXIDATIVE STRESS; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; TUMOR CELL LINE; UPREGULATION; ANTAGONISTS AND INHIBITORS; CELL CULTURE; CYTOLOGY; DRUG EFFECTS; GENETICS; INDUCED PLURIPOTENT STEM CELL; METABOLISM; MITOCHONDRION; RADIATION RESPONSE; RNA INTERFERENCE; ULTRAVIOLET RADIATION;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL DIFFERENTIATION; CELLS, CULTURED; DNA DAMAGE; DNA, MITOCHONDRIAL; FIBROBLASTS; GLUTATHIONE; GLUTATHIONE PEROXIDASE; HUMANS; HYDROGEN PEROXIDE; INDUCED PLURIPOTENT STEM CELLS; MITOCHONDRIA; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; RNA INTERFERENCE; RNA, SMALL INTERFERING; ULTRAVIOLET RAYS;

EID: 84929275335     PISSN: 22136711     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.stemcr.2015.04.004     Document Type: Article

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