Ex vivo gene therapy using patient iPSC-derived NSCs reverses pathology in the brain of a homologous mouse model

Stem Cell Reports

Volumn 4, Issue 5, 2015, Pages 835-846

  Griffin, Tagan A ^a   Anderson, Hayley C ^a   Wolfe, John H ^a,b  

^a CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN DISEASE; CONTROLLED STUDY; EX VIVO STUDY; GENE THERAPY; HUMAN; HUMAN CELL; MOUSE; NERVE CELL DIFFERENTIATION; NEURAL STEM CELL; NEURAL STEM CELL TRANSPLANTATION; NONHUMAN; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; TRANSPOSON; WHITE MATTER; ADULT; ANIMAL; BRAIN; C57BL MOUSE; CELL CULTURE; CELL DIFFERENTIATION; CYTOLOGY; DEPENDOPARVOVIRUS; DISEASE MODEL; FEMALE; GENETICS; KARYOTYPING; METABOLISM; MUCOPOLYSACCHARIDOSIS VII; NONOBESE DIABETIC MOUSE; NUCLEAR REPROGRAMMING; PATHOLOGY; SCID MOUSE; TRANSPLANTATION;

MUS;

TRANSCRIPTION FACTOR;

ADULT; ANIMALS; BRAIN; CELL DIFFERENTIATION; CELLS, CULTURED; CELLULAR REPROGRAMMING; DEPENDOVIRUS; DISEASE MODELS, ANIMAL; FEMALE; GENETIC THERAPY; HUMANS; KARYOTYPING; MICE; MICE, INBRED C57BL; MICE, INBRED NOD; MICE, SCID; MUCOPOLYSACCHARIDOSIS VII; NEURAL STEM CELLS; PLURIPOTENT STEM CELLS; TRANSCRIPTION FACTORS;

EID: 84929265416     PISSN: 22136711     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.stemcr.2015.02.022     Document Type: Article

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