Uncoupling protein 1 and sarcolipin are required to maintain optimal thermogenesis, and loss of both systems compromises survival of mice under cold stress

Journal of Biological Chemistry

Volumn 290, Issue 19, 2015, Pages 12282-12289

  Rowland, Leslie A ^a   Bal, Naresh C ^a   Kozak, Leslie P ^b   Periasamy, Muthu ^a  

^a THE OHIO STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

^b INSTITUTE OF ANIMAL REPRODUCTION AND FOOD RESEARCH   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

MUSCLE; TISSUE;

ADIPOSE TISSUE; COLD CHALLENGE; COLD EXPOSURE; HEAT PRODUCTION; SKELETAL MUSCLE; UNCOUPLING PROTEIN-1; UP-REGULATION; WHITE ADIPOSE TISSUES;

MAMMALS;

CATECHOLAMINE; SARCOLIPIN; UNCLASSIFIED DRUG; UNCOUPLING PROTEIN; UNCOUPLING PROTEIN 1; ION CHANNEL; MITOCHONDRIAL PROTEIN; MITOCHONDRIAL UNCOUPLING PROTEIN; MUSCLE PROTEIN; PROTEOLIPID;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BROWN ADIPOSE TISSUE; CATECHOLAMINE URINE LEVEL; COLD ACCLIMATIZATION; COLD EXPOSURE; COLD SENSITIVITY; COLD STRESS; CONTROLLED STUDY; DEPLETION; DOWN REGULATION; ENERGY EXPENDITURE; FEMALE; GLYCATION; HYPOTHERMIA; MALE; MOUSE; NONHUMAN; OXYGEN CONSUMPTION; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; SURVIVAL; SURVIVAL RATE; THERMOGENESIS; UPREGULATION; WEIGHT REDUCTION; WHITE ADIPOSE TISSUE; ANIMAL; BODY WEIGHT; C57BL MOUSE; COLD; KNOCKOUT MOUSE; PHYSIOLOGICAL STRESS; PHYSIOLOGY; SKELETAL MUSCLE; URINE;

MUS;

ADIPOSE TISSUE, BROWN; ANIMALS; BODY WEIGHT; CATECHOLAMINES; COLD TEMPERATURE; FEMALE; ION CHANNELS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MITOCHONDRIAL PROTEINS; MUSCLE PROTEINS; MUSCLE, SKELETAL; OXYGEN CONSUMPTION; PROTEOLIPIDS; STRESS, PHYSIOLOGICAL; THERMOGENESIS; UP-REGULATION;

EID: 84929223175     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.637603     Document Type: Article

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