The formulation of a pressurized metered dose inhaler containing theophylline for inhalation

European Journal of Pharmaceutical Sciences

Volumn 76, Issue , 2015, Pages 68-72

  Zhu, Bing ^a   Haghi, Mehra ^a,b   Goud, Mary ^c   Young, Paul M ^a   Traini, Daniela ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

^b UNIVERSITY OF TECHNOLOGY SYDNEY   (Australia)

^c AVANS UNIVERSITY OF APPLIED SCIENCES   (Netherlands)

Author keywords

Chronic obstructive pulmonary disease; Pressurized metered dose inhaler; Theophylline; Toxicity

Indexed keywords

ALCOHOL; INTERLEUKIN 8; NORFLURANE; THEOPHYLLINE; TUMOR NECROSIS FACTOR ALPHA; AEROSOL; ANTIINFLAMMATORY AGENT; AUTACOID; BRONCHODILATING AGENT; FLUORINATED HYDROCARBON; IL8 PROTEIN, HUMAN; PROPELLANT; TUMOR NECROSIS FACTOR;

AEROSOL; ARTICLE; CELL VIABILITY; CELL VIABILITY ASSAY; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG FORMULATION; DRUG MIXTURE; DRUG SOLUBILITY; DRUG STRUCTURE; DRUG TRANSPORT; ENZYME ACTIVATION; HUMAN; HUMAN CELL; IC50; IN VITRO STUDY; LOW DRUG DOSE; METERED DOSE INHALER; MOLECULAR SIZE; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; CELL LINE; CHEMISTRY; DEVICES; DRUG DELIVERY SYSTEM; DRUG EFFECTS; EPITHELIUM CELL; EQUIPMENT DESIGN; INHALATIONAL DRUG ADMINISTRATION; MEDICINAL CHEMISTRY; METABOLISM; PARTICLE SIZE; PATHOPHYSIOLOGY; PHARMACEUTICS; PRESSURE; PROCEDURES; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; RESPIRATORY TRACT MUCOSA; SECRETION (PROCESS); SOLUBILITY;

ADMINISTRATION, INHALATION; AEROSOL PROPELLANTS; AEROSOLS; ANTI-INFLAMMATORY AGENTS; BRONCHODILATOR AGENTS; CELL LINE; CHEMISTRY, PHARMACEUTICAL; DRUG DELIVERY SYSTEMS; EPITHELIAL CELLS; EQUIPMENT DESIGN; ETHANOL; HUMANS; HYDROCARBONS, FLUORINATED; INFLAMMATION MEDIATORS; INTERLEUKIN-8; METERED DOSE INHALERS; MICROSCOPY, ELECTRON, SCANNING; PARTICLE SIZE; PRESSURE; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; RESPIRATORY MUCOSA; SOLUBILITY; TECHNOLOGY, PHARMACEUTICAL; THEOPHYLLINE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84929170562     PISSN: 09280987     EISSN: 18790720     Source Type: Journal    
DOI: 10.1016/j.ejps.2015.04.016     Document Type: Article

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