Poly(Q) expansions in ATXN7 affect solubility but not activity of the SAGA deubiquitinating module

Molecular and Cellular Biology

Volumn 35, Issue 10, 2015, Pages 1777-1787

  Lan, Xianjiang ^a   Koutelou, Evangelia ^a   Schibler, Andria C ^a   Chen, Yi Chun ^b   Grant, Patrick A ^c   Denta, Sharon Y R ^a  

^a UNIVERSITY OF TEXAS   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

^c UNIVERSITY OF VIRGINIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEUBIQUITINASE; HISTONE H2B; PEPTIDES AND PROTEINS; POLYGLUTAMINE; PROTEIN ATXN7; SAGA ANTIGEN; UNCLASSIFIED DRUG; ATAXIN 7; ATXN7 PROTEIN, HUMAN; ATXN7 PROTEIN, MOUSE; NERVE PROTEIN; PEPTIDE;

AMINO TERMINAL SEQUENCE; ANIMAL TISSUE; ARTICLE; CEREBELLUM; ENZYME ACTIVITY; HISTONE UBIQUITINATION; HUMAN; HUMAN CELL; IN VITRO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SOLUBILITY; ANIMAL; ASTROCYTE; DISEASE MODEL; GENETICS; HEK293 CELL LINE; METABOLISM; PATHOLOGY; SF9 CELL LINE; SPINOCEREBELLAR DEGENERATION; SPODOPTERA;

MUS;

ANIMALS; ASTROCYTES; ATAXIN-7; CEREBELLUM; DISEASE MODELS, ANIMAL; HEK293 CELLS; HUMANS; IN VITRO TECHNIQUES; MICE; NERVE TISSUE PROTEINS; PEPTIDES; SF9 CELLS; SOLUBILITY; SPINOCEREBELLAR ATAXIAS; SPODOPTERA; UBIQUITIN-SPECIFIC PROTEASES;

EID: 84929163852     PISSN: 02707306     EISSN: 10985549     Source Type: Journal    
DOI: 10.1128/MCB.01454-14     Document Type: Article

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