Loss of Drosophila Ataxin-7, a SAGA subunit, reduces H2B ubiquitination and leads to neural and retinal degeneration

Genes and Development

Volumn 28, Issue 3, 2014, Pages 259-272

  Mohan, Ryan D ^a   Dialynas, George ^a   Weake, Vikki M ^b   Liu, Jianqi ^a   Martin Brown, Skylar ^a   Florens, Laurence ^a   Washburn, Michael P ^a,c   Workman, Jerry L ^a   Abmayr, Susan M ^a,c  

^a STOWERS INSTITUTE FOR MEDICAL RESEARCH   (United States)

^b PURDUE UNIVERSITY   (United States)

^c UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

Author keywords

H2B ubiquitination; SAGA complex; Spinocerebellar ataxia

Indexed keywords

ATAXIN 7; DEUBIQUITINASE; HISTONE H3; TRANSCRIPTION FACTOR SAGA;

AMINO ACID SEQUENCE; ARTICLE; CG9866 GENE; CHROMATIN ASSEMBLY AND DISASSEMBLY; CONTROLLED STUDY; DROSOPHILA; GEL FILTRATION CHROMATOGRAPHY; GENE; HISTONE ACETYLATION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; NERVE DEGENERATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; RETINA DEGENERATION; UBIQUITINATION; YEAST;

H2B UBIQUITINATION; SAGA COMPLEX; SPINOCEREBELLAR ATAXIA;

AMINO ACID SEQUENCE; ANIMALS; DROSOPHILA MELANOGASTER; HELA CELLS; HISTONES; HUMANS; LONGEVITY; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MULTIPROTEIN COMPLEXES; NERVE TISSUE PROTEINS; NEURONS; PROMOTER REGIONS, GENETIC; PROTEIN STRUCTURE, QUATERNARY; RETINA; SEQUENCE ALIGNMENT; UBIQUITIN-SPECIFIC PROTEASES; UBIQUITINATION;

EID: 84893434633     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.225151.113     Document Type: Article

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