Direct inhibition of Gcn5 protein catalytic activity by polyglutamine-expanded ataxin-7

Journal of Biological Chemistry

Volumn 288, Issue 47, 2013, Pages 34266-34275

  Burke, Tara L ^a   Miller, Jaime L ^a   Grant, Patrick A ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DOMINANT MECHANISM; HISTONE ACETYLTRANSFERASES; IN-VITRO; N-TERMINALS; POLYGLUTAMINE (POLYQ); REGULATORY PROTEIN; SAGA COMPLEXES;

CATALYST ACTIVITY;

PROTEINS;

ADA2 PROTEIN; ADA3 PROTEIN; ATAXIN 7; HISTONE ACETYLTRANSFERASE GCN5; POLYGLUTAMINE; REGULATOR PROTEIN; TRANSCRIPTION FACTOR SAGA; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CONTROLLED STUDY; ENZYME INHIBITION; GAL1 GENE; GAL7 GENE; GENE; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING;

GENE EXPRESSION; HISTONE ACETYLASE; HISTONE MODIFICATION; NEURODEGENERATION; POLYGLUTAMINE DISEASE; PROTEIN COMPLEXES; SPINOCEREBELLAR ATAXIA TYPE 7;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; GALECTINS; HISTONE ACETYLTRANSFERASES; HUMANS; NERVE TISSUE PROTEINS; P300-CBP TRANSCRIPTION FACTORS; PEPTIDES; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SPINOCEREBELLAR ATAXIAS; TRANSCRIPTION FACTORS;

EID: 84888328883     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.487538     Document Type: Article

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