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Volumn 29, Issue 10, 2014, Pages 1189-1198

The impact of pyrvinium pamoate on colon cancer cell viability

Author keywords

Colon cancer cell lines; Myc; Pyrvinium pamoate; WNT pathway

Indexed keywords

ANTINEOPLASTIC AGENT; BETA CATENIN; FLUOROURACIL; PYRVINIUM EMBONATE;

EID: 84929132554     PISSN: 01791958     EISSN: 14321262     Source Type: Journal    
DOI: 10.1007/s00384-014-1975-y     Document Type: Article
Times cited : (31)

References (29)
  • 3
    • 0035522894 scopus 로고    scopus 로고
    • Two genetic hits (more or less) to cancer
    • PID: 11905807, COI: 1:CAS:528:DC%2BD38XlvF2qsLg%3D
    • Knudson AG (2001) Two genetic hits (more or less) to cancer. Nat Rev Cancer 1(2):157–162
    • (2001) Nat Rev Cancer , vol.1 , Issue.2 , pp. 157-162
    • Knudson, A.G.1
  • 4
    • 84863922124 scopus 로고    scopus 로고
    • Comprehensive molecular characterization of human colon and rectal cancer
    • Cancer Genome Atlas Network (2012) Comprehensive molecular characterization of human colon and rectal cancer. Nature 487:330–337
    • (2012) Nature , vol.487 , pp. 330-337
    • Cancer Genome Atlas Network1
  • 6
    • 84880419972 scopus 로고    scopus 로고
    • Polymorphisms of GSTP1, ERCC2 and TS-3’UTR are associated with the clinical outcome of mFOLFOX6 in colorectal cancer patients
    • PID: 24137384, COI: 1:CAS:528:DC%2BC3sXhsFSmu77O
    • Kumamoto K, Ishibashi K, Okada N, Tajima Y, Kuwabara K, Kumagai Y, Baba H, Haga N, Ishida H (2013) Polymorphisms of GSTP1, ERCC2 and TS-3’UTR are associated with the clinical outcome of mFOLFOX6 in colorectal cancer patients. Oncol Lett 6(3):648–654
    • (2013) Oncol Lett , vol.6 , Issue.3 , pp. 648-654
    • Kumamoto, K.1    Ishibashi, K.2    Okada, N.3    Tajima, Y.4    Kuwabara, K.5    Kumagai, Y.6    Baba, H.7    Haga, N.8    Ishida, H.9
  • 7
    • 61449182121 scopus 로고    scopus 로고
    • Principles of cancer therapy: oncogene and non-oncogene addiction
    • PID: 19269363, COI: 1:CAS:528:DC%2BD1MXltFSnsLw%3D
    • Luo J, Solimini NL, Elledge SJ (2009) Principles of cancer therapy: oncogene and non-oncogene addiction. Cell 136(5):823–837
    • (2009) Cell , vol.136 , Issue.5 , pp. 823-837
    • Luo, J.1    Solimini, N.L.2    Elledge, S.J.3
  • 8
    • 33751530490 scopus 로고    scopus 로고
    • Mining the Wnt pathway for cancer therapeutics
    • PID: 17139285, COI: 1:CAS:528:DC%2BD28Xht1Kju7vK
    • Barker N, Clevers H (2006) Mining the Wnt pathway for cancer therapeutics. Nat Rev Drug Discov 5(12):997–1014
    • (2006) Nat Rev Drug Discov , vol.5 , Issue.12 , pp. 997-1014
    • Barker, N.1    Clevers, H.2
  • 9
    • 70349695861 scopus 로고    scopus 로고
    • Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling
    • PID: 19759537, COI: 1:CAS:528:DC%2BD1MXhtFentbzP
    • Huang SM, Mishina YM, Liu S, Cheung A, Stegmeier F et al (2009) Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling. Nature 461(7264):614–620
    • (2009) Nature , vol.461 , Issue.7264 , pp. 614-620
    • Huang, S.M.1    Mishina, Y.M.2    Liu, S.3    Cheung, A.4    Stegmeier, F.5
  • 10
    • 84889051925 scopus 로고    scopus 로고
    • XAV939, a tankyrase 1 inhibitior, promotes cell apoptosis in neuroblastoma cell lines by inhibiting Wnt/β-catenin signaling pathway
    • PID: 24308762
    • Tian XH, Hou WJ, Fang Y, Fan J, Tong H, Bai SL, Chen Q, Xu H, Li Y (2013) XAV939, a tankyrase 1 inhibitior, promotes cell apoptosis in neuroblastoma cell lines by inhibiting Wnt/β-catenin signaling pathway. J Exp Clin Cancer Res 32(1):100
    • (2013) J Exp Clin Cancer Res , vol.32 , Issue.1 , pp. 100
    • Tian, X.H.1    Hou, W.J.2    Fang, Y.3    Fan, J.4    Tong, H.5    Bai, S.L.6    Chen, Q.7    Xu, H.8    Li, Y.9
  • 12
    • 84876924060 scopus 로고    scopus 로고
    • Pyrvinium pamoate does not activate protein kinase CK1, but promotes Akt/PKB down-regulation and GSK3 activation
    • PID: 23438105, COI: 1:CAS:528:DC%2BC3sXms1WhtbY%3D
    • Venerando A, Girardi C, Ruzzene M, Pinna LA (2013) Pyrvinium pamoate does not activate protein kinase CK1, but promotes Akt/PKB down-regulation and GSK3 activation. Biochem J 452(1):131–137
    • (2013) Biochem J , vol.452 , Issue.1 , pp. 131-137
    • Venerando, A.1    Girardi, C.2    Ruzzene, M.3    Pinna, L.A.4
  • 13
    • 84871748026 scopus 로고    scopus 로고
    • Establishment, characterization and chemosensitivity of three mismatch repair deficient cell lines from sporadic and inherited colorectal carcinomas
    • PID: 23300683, COI: 1:CAS:528:DC%2BC3sXptVSjtQ%3D%3D
    • Maletzki C, Stier S, Gruenert U, Gock M, Ostwald C, Prall F, Linnebacher M (2012) Establishment, characterization and chemosensitivity of three mismatch repair deficient cell lines from sporadic and inherited colorectal carcinomas. PLoS One 7(12):e52485
    • (2012) PLoS One , vol.7 , Issue.12 , pp. e52485
    • Maletzki, C.1    Stier, S.2    Gruenert, U.3    Gock, M.4    Ostwald, C.5    Prall, F.6    Linnebacher, M.7
  • 14
    • 84860333654 scopus 로고    scopus 로고
    • Natural resistance to ascorbic acid induced oxidative stress is mainly mediated by catalase activity in human cancer cells and catalase-silencing sensitizes to oxidative stress
    • PID: 22551313, COI: 1:CAS:528:DC%2BC38Xhslehs73I
    • Klingelhoeffer C, Kämmerer U, Koospal M, Mühling B, Schneider S, Kapp M, Kübler A, Germer C-T, Otto C (2012) Natural resistance to ascorbic acid induced oxidative stress is mainly mediated by catalase activity in human cancer cells and catalase-silencing sensitizes to oxidative stress. BMC Complement Altern Med 12:61
    • (2012) BMC Complement Altern Med , vol.12 , pp. 61
    • Klingelhoeffer, C.1    Kämmerer, U.2    Koospal, M.3    Mühling, B.4    Schneider, S.5    Kapp, M.6    Kübler, A.7    Germer, C.-T.8    Otto, C.9
  • 15
    • 34250927297 scopus 로고
    • Direct complexometric calcium determination in serum with calcein as indicator
    • PID: 13588918, COI: 1:CAS:528:DyaG1MXls12htA%3D%3D
    • Langendorf H (1958) Direct complexometric calcium determination in serum with calcein as indicator. Klin Wochenschr 36(17):829–831
    • (1958) Klin Wochenschr , vol.36 , Issue.17 , pp. 829-831
    • Langendorf, H.1
  • 16
    • 0036142782 scopus 로고    scopus 로고
    • The alpha(1)beta(1) and alpha(2)beta(1) integrins provide critical support for vascular endothelial growth factor signaling, endothelial cell migration, and tumor angiogenesis
    • PID: 11786413, COI: 1:CAS:528:DC%2BD38XnvFehuw%3D%3D
    • Senger DR, Perruzzi CA, Streit M, Koteliansky VE, de Fougerolles AR, Detmar M (2002) The alpha(1)beta(1) and alpha(2)beta(1) integrins provide critical support for vascular endothelial growth factor signaling, endothelial cell migration, and tumor angiogenesis. Am J Pathol 160(1):195–204
    • (2002) Am J Pathol , vol.160 , Issue.1 , pp. 195-204
    • Senger, D.R.1    Perruzzi, C.A.2    Streit, M.3    Koteliansky, V.E.4    de Fougerolles, A.R.5    Detmar, M.6
  • 17
    • 17344392308 scopus 로고    scopus 로고
    • A new mathematical model for relative quantification in real-time RT-PCR
    • PID: 11328886, COI: 1:STN:280:DC%2BD38nis12jtw%3D%3D
    • Pfaffl MW (2001) A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res 29(9):e45
    • (2001) Nucleic Acids Res , vol.29 , Issue.9 , pp. e45
    • Pfaffl, M.W.1
  • 21
    • 4544229589 scopus 로고    scopus 로고
    • Antitumor activity of pyrvinium pamoate, 6-(dimethylamino)-2-[2-(2,5-dimethyl-1-phenyl-1H-pyrrol-3-yl)ethenyl]-1-methyl-quinolinium pamoate salt, showing preferential cytotoxicity during glucose starvation
    • PID: 15298733, COI: 1:CAS:528:DC%2BD2cXot1Kisbs%3D
    • Esumi H, Lu J, Kurashima Y, Hanaoka T (2004) Antitumor activity of pyrvinium pamoate, 6-(dimethylamino)-2-[2-(2,5-dimethyl-1-phenyl-1H-pyrrol-3-yl)ethenyl]-1-methyl-quinolinium pamoate salt, showing preferential cytotoxicity during glucose starvation. Cancer Sci 95(8):685–690
    • (2004) Cancer Sci , vol.95 , Issue.8 , pp. 685-690
    • Esumi, H.1    Lu, J.2    Kurashima, Y.3    Hanaoka, T.4
  • 22
    • 77955301066 scopus 로고    scopus 로고
    • The NADH-fumarate reductase system, a novel mitochondrial energy metabolism, is a new target for anticancer therapy in tumor microenvironments
    • PID: 20649538, COI: 1:CAS:528:DC%2BC3cXhtFegsLrO
    • Tomitsuka E, Kita K, Esumi H (2010) The NADH-fumarate reductase system, a novel mitochondrial energy metabolism, is a new target for anticancer therapy in tumor microenvironments. Ann N Y Acad Sci 1201:44–49
    • (2010) Ann N Y Acad Sci , vol.1201 , pp. 44-49
    • Tomitsuka, E.1    Kita, K.2    Esumi, H.3
  • 23
    • 84864432128 scopus 로고    scopus 로고
    • An anticancer agent, pyrvinium pamoate inhibits the NADH-fumarate reductase system—a unique mitochondrial energy metabolism in tumour microenvironments
    • PID: 22528668, COI: 1:CAS:528:DC%2BC38XhtFant7nL
    • Tomitsuka E, Kita K, Esumi H (2012) An anticancer agent, pyrvinium pamoate inhibits the NADH-fumarate reductase system—a unique mitochondrial energy metabolism in tumour microenvironments. J Biochem 152(2):171–183
    • (2012) J Biochem , vol.152 , Issue.2 , pp. 171-183
    • Tomitsuka, E.1    Kita, K.2    Esumi, H.3
  • 24
    • 84858073770 scopus 로고    scopus 로고
    • Pyrvinium pamoate inhibits proliferation of myeloma/erythroleukemia cells by suppressing mitochondrial respiratory complex I and STAT3
    • PID: 22210382, COI: 1:CAS:528:DC%2BC38Xjs1Gmtrs%3D
    • Harada Y, Ishii I, Hatake K, Kasahara T (2012) Pyrvinium pamoate inhibits proliferation of myeloma/erythroleukemia cells by suppressing mitochondrial respiratory complex I and STAT3. Cancer Lett 319(1):83–88
    • (2012) Cancer Lett , vol.319 , Issue.1 , pp. 83-88
    • Harada, Y.1    Ishii, I.2    Hatake, K.3    Kasahara, T.4
  • 25
    • 58049213923 scopus 로고    scopus 로고
    • Pyrvinium targets the unfolded protein response to hypoglycemia and its anti-tumor activity is enhanced by combination therapy
    • PID: 19079611
    • Yu DH, Macdonald J, Liu G, Lee AS, Ly M, Davis T, Ke N, Zhou D, Wong-Staal F, Li QX (2008) Pyrvinium targets the unfolded protein response to hypoglycemia and its anti-tumor activity is enhanced by combination therapy. PLoS One 3(12):e3951
    • (2008) PLoS One , vol.3 , Issue.12 , pp. e3951
    • Yu, D.H.1    Macdonald, J.2    Liu, G.3    Lee, A.S.4    Ly, M.5    Davis, T.6    Ke, N.7    Zhou, D.8    Wong-Staal, F.9    Li, Q.X.10
  • 28
    • 80155191242 scopus 로고    scopus 로고
    • Oncogene addiction as a foundational rationale for targeted anti-cancer therapy: promises and perils
    • PID: 21953712, COI: 1:CAS:528:DC%2BC3MXhsV2qtb7P
    • Torti D, Trusolino L (2011) Oncogene addiction as a foundational rationale for targeted anti-cancer therapy: promises and perils. EMBO Mol Med 3(11):623–636
    • (2011) EMBO Mol Med , vol.3 , Issue.11 , pp. 623-636
    • Torti, D.1    Trusolino, L.2
  • 29
    • 84870846269 scopus 로고    scopus 로고
    • Synergistic effects of combined Wnt/KRAS inhibition in colorectal cancer cells
    • Mologni L, Brussolo S, Ceccon M, Gambacorti-Passerini C (2012) Synergistic effects of combined Wnt/KRAS inhibition in colorectal cancer cells. PLoS One 7(12):e514492
    • (2012) PLoS One , vol.7 , Issue.12 , pp. e514492
    • Mologni, L.1    Brussolo, S.2    Ceccon, M.3    Gambacorti-Passerini, C.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.