Human adipocytes stimulate invasion of breast cancer MCF-7 cells by secreting IGFBP-2

PLoS ONE

Volumn 10, Issue 3, 2015, Pages

  Wang, Chen ^a   Gao, Chao ^b   Meng, Kui ^c   Qiao, Haishi ^a   Wang, Yong ^a  

^a MEDICAL SCHOOL OF NANJING UNIVERSITY   (China)

^b THE FIRST AFFILIATED HOSPITAL OF NANJING MEDICAL UNIVERSITY   (China)

^c NANJING UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPOCYTOKINE; ADIPONECTIN; ANGIOPOIETIN 1; ANGIOPOIETIN LIKE 4; BETA CATENIN; EPITHELIAL DERIVED NEUTROPHIL ACTIVATING FACTOR 78; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GELATINASE A; GELATINASE B; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; INSULIN; INTERLEUKIN 6 RECEPTOR; INTERLEUKIN 6 SOLUBLE RECEPTOR; INTERLEUKIN 8; LEPTIN; MACROPHAGE MIGRATION INHIBITION FACTOR; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 3; NERVE CELL ADHESION MOLECULE; PLATELET DERIVED GROWTH FACTOR AA; PLATELET DERIVED GROWTH FACTOR AB; PLATELET DERIVED GROWTH FACTOR BB; PROTEIN ZO1; RANTES; SOMATOMEDIN BINDING PROTEIN 2; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; UVOMORULIN; VIMENTIN; IGFBP-2 PROTEIN, HUMAN;

ADIPOCYTE; ARTICLE; BREAST CANCER; BREAST METASTASIS; CELL COMMUNICATION; CELL CONTACT; CELL INVASION; CELL MOTILITY; CONTROLLED STUDY; CYTOKINE RELEASE; DOWN REGULATION; ENZYME INDUCTION; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MCF 7 CELL LINE; PHENOTYPE; TUMOR INVASION; BREAST TUMOR; COCULTURE; MCF-7 CELL LINE; METABOLISM; METASTASIS; PATHOLOGY; SECRETION (PROCESS);

ADIPOCYTES; BREAST NEOPLASMS; COCULTURE TECHNIQUES; FEMALE; HUMANS; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 2; MCF-7 CELLS; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS;

EID: 84929120995     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0119348     Document Type: Article

References (32)

1. Wiseman BS, Werb Z. Stromal effects on mammary gland development and breast cancer. Science. 2002; 296: 1046-1049. PMID: 12004111
2. Subbaramaiah K, Howe LR, Bhardwaj P, Du B, Gravaghi C, Yantiss RK, et al. Obesity is associated with inflammation and elevated aromatase expression in the mouse mammary gland. Cancer prevention research. 2011; 4: 329-346. doi: 10.1158/1940-6207.CAPR-10-0381 PMID: 21372033
3. Dirat B, Bochet L, Escourrou G, Valet P, Muller C. Unraveling the obesity and breast cancer links: a role for cancer-associated adipocytes? Endocrine development. 2010; 19: 45-52. doi: 10.1159/000316896 PMID: 20551667
4. Iyengar P, Combs TP, Shah SJ, Gouon-Evans V, Pollard JW, Albanese C, et al. Adipocyte-secreted factors synergistically promote mammary tumorigenesis through induction of anti-apoptotic transcriptional programs and proto-oncogene stabilization. Oncogene. 2003; 22: 6408-6423. PMID: 14508521
5. Carter JC, Church FC. Obesity and breast cancer: the roles of peroxisome proliferator-activated receptor-gamma and plasminogen activator inhibitor-1. PPAR research. 2009; 2009: 345320. doi: 10.1155/2009/345320 PMID: 19672469
6. Park J, Euhus DM, Scherer PE. Paracrine and endocrine effects of adipose tissue on cancer development and progression. Endocrine reviews. 2011; 32: 550-570. doi: 10.1210/er.2010-0030 PMID: 21642230
7. Celis JE, Moreira JM, Cabezon T, Gromov P, Friis E, Rank F, et al. Identification of extracellular and intracellular signaling components of the mammary adipose tissue and its interstitial fluid in high risk breast cancer patients: toward dissecting the molecular circuitry of epithelial-adipocyte stromal cell interactions. Molecular & cellular proteomics. 2005; 4:492-522.
8. Dirat B, Bochet L, Dabek M, Daviaud D, Dauvillier S, Majed B, et al. Cancer-associated adipocytes exhibit an activated phenotype and contribute to breast cancer invasion. Cancer research. 2011; 71: 2455-2465. doi: 10.1158/0008-5472.CAN-10-3323 PMID: 21459803
9. D'Esposito V, Passaretti F, Hammarstedt A, Liguoro D, Terracciano D, Molea G, et al. Adipocyte-released insulin-like growth factor-1 is regulated by glucose and fatty acids and controls breast cancer cell growth in vitro. Diabetologia. 2012; 55: 2811-2822. doi: 10.1007/s00125-012-2629-7 PMID: 22798065
10. Miyoshi Y, Funahashi T, Tanaka S, Taguchi T, Tamaki Y, Shimomura I, et al. High expression of leptin receptor mRNA in breast cancer tissue predicts poor prognosis for patients with high, but not low, serum leptin levels. International journal of cancer. Journal international du cancer. 2006; 118: 1414-1419. PMID: 16206269
11. Schaffler A, Scholmerich J, Buechler C. Mechanisms of disease: adipokines and breast cancer - endocrine and paracrine mechanisms that connect adiposity and breast cancer. Nature clinical practice. Endocrinology & metabolism. 2007; 3: 345-354.
12. Dalmas E, Clement K, Guerre-Millo M. Defining macrophage phenotype and function in adipose tissue. Trends in immunology. 2011; 32: 307-314. doi: 10.1016/j.it.2011.04.008 PMID: 21616718
13. Kim JH, Kim KY, Jeon JH, Lee SH, Hwang JE, Lee JH, et al. Adipocyte culture medium stimulates production of macrophage inhibitory cytokine 1 in MDA-MB-231 cells. Cancer letters. 2008; 261: 253-262. doi: 10.1016/j.canlet.2007.11.020 PMID: 18164124
14. Kang X, Xie Y, Kniss DA. Adipose tissue model using three-dimensional cultivation of preadipocytes seeded onto fibrous polymer scaffolds. Tissue engineering. 2005; 11: 458-468. PMID: 15869424
15. Wang C, Bian Z, Wei D, Zhang JG. miR-29b regulates migration of human breast cancer cells. Molecular and cellular biochemistry. 2011; 352: 197-207. doi: 10.1007/s11010-011-0755-z PMID: 21359530
16. Iyengar P, Espina V, Williams TW, Lin Y, Berry D, Jelicks LA, et al. Adipocyte-derived collagen VI affects early mammary tumor progression in vivo, demonstrating a critical interaction in the tumor/stroma microenvironment. The Journal of clinical investigation. 2005; 115: 1163-1176. PMID: 15841211
17. Motrescu ER, Rio MC. Cancer cells, adipocytes and matrix metalloproteinase 11: a vicious tumor progression cycle. Biological chemistry. 2008; 389: 1037-1041. doi: 10.1515/BC.2008.110 PMID: 18979628
18. Slattery ML, John E, Torres-Mejia G, Stern M, Lundgreen A, Hines L, et al. Matrix metalloproteinase genes are associated with breast cancer risk and survival: the Breast Cancer Health Disparities Study. PloS one. 2013; 8:e63165. doi: 10.1371/journal.pone.0063165 PMID: 23696797
19. McCawley LJ, Matrisian LM. Matrix metalloproteinases: they're not just for matrix anymore! Current opinion in cell biology. 2001; 13: 534-540. PMID: 11544020
20. Egeblad M, Werb Z. New functions for the matrix metalloproteinases in cancer progression. Nature reviews Cancer. 2002; 2: 161-174. PMID: 11990853
21. Yilmaz M, Christofori G. EMT, the cytoskeleton, and cancer cell invasion. Cancer metastasis reviews. 2009; 28: 15-33. doi: 10.1007/s10555-008-9169-0 PMID: 19169796
22. Andarawewa KL, Motrescu ER, Chenard MP, Gansmuller A, Stoll I, Tomasetto C, et al. Stromelysin-3 is a potent negative regulator of adipogenesis participating to cancer cell-adipocyte interaction/crosstalk at the tumor invasive front. Cancer research. 2005; 65: 10862-10871. PMID: 16322233
23. Guerrero J, Tobar N, Caceres M, Espinoza L, Escobar P, Dotor J, et al. Soluble factors derived from tumor mammary cell lines induce a stromal mammary adipose reversion in human and mice adipose cells. Possible role of TGF-beta1 and TNF-alpha. Breast cancer research and treatment. 2010; 119: 497-508. doi: 10.1007/s10549-009-0491-1 PMID: 19649705
24. Das SK, Eder S, Schauer S, Diwoky C, Temmel H, Guertl B, et al. Adipose triglyceride lipase contributes to cancer-associated cachexia. Science. 2011; 333: 233-238. doi: 10.1126/science.1198973 PMID: 21680814
25. Ryden M, Jocken J, van Harmelen V, Dicker A, Hoffstedt J, Wirén M, et al. Comparative studies of the role of hormone-sensitive lipase and adipose triglyceride lipase in human fat cell lipolysis. American journal of physiology. Endocrinology and metabolism. 2007; 292: E1847-1855. PMID: 17327373
26. Foulstone EJ, Zeng L, Perks CM, Holly JM. Insulin-like growth factor binding protein 2 (IGFBP-2) promotes growth and survival of breast epithelial cells: novel regulation of the estrogen receptor. Endocrinology. 2013; 154: 1780-1793. doi: 10.1210/en.2012-1970 PMID: 23515291
27. Heneweer M, Muusse M, Dingemans M, de Jong PC, van den Berg M, Sanderson JT. Co-culture of primary human mammary fibroblasts and MCF-7 cells as an in vitro breast cancer model. Toxicological sciences: an official journal of the Society of Toxicology. 2005; 83: 257-263. PMID: 15525692
28. Todorovic-Rakovic N, Milovanovic J. Interleukin-8 in breast cancer progression. Journal of interferon & cytokine research: the official journal of the International Society for Interferon and Cytokine Research. 2013; 33: 563-570.
29. Gnerlich JL, Yao KA, Fitchev PS, Goldschmidt RA, Bond MC, Cornwell M, et al. Peritumoral expression of adipokines and fatty acids in breast cancer. Annals of surgical oncology. 2013; 20 Suppl 3: S731-738. doi: 10.1245/s10434-013-3274-1 PMID: 24052317
30. Verjans E, Noetzel E, Bektas N, Schutz AK, Lue H, Lennartz B, et al. Dual role of macrophage migration inhibitory factor (MIF) in human breast cancer. BMC cancer. 2009; 9: 230. doi: 10.1186/1471-2407-9-230 PMID: 19602265
31. Drabsch Y, ten Dijke P. TGF-beta signaling in breast cancer cell invasion and bone metastasis. Journal of mammary gland biology and neoplasia. 2011; 16: 97-108. doi: 10.1007/s10911-011-9217-1 PMID: 21494783
32. Kricker JA, Towne CL, Firth SM, Herington AC, Upton Z. Structural and functional evidence for the interaction of insulin-like growth factors (IGFs) and IGF binding proteins with vitronectin. Endocrinology. 2003; 144: 2807-2815. PMID: 12810534