Th1-like ICOS+ Foxp3+ Treg cells preferentially express CXCR3 and home to β-islets during pre-diabetes in BDC2.5 NOD mice

PLoS ONE

Volumn 10, Issue 5, 2015, Pages

  Kornete, Mara ^a   Mason, Edward S ^a   Girouard, Julien ^a   Lafferty, Erin I ^a   Qureshi, Salman ^a   Piccirillo, Ciriaco A ^a,b  

^a MCGILL UNIVERSITY   (Canada)

^b RESEARCH INSTITUTE OF THE MCGILL UNIVERSITY HEALTH CENTRE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CXCR3; CXCL11 CHEMOKINE; CXCL9 CHEMOKINE; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INDUCIBLE T CELL COSTIMULATOR; TRANSCRIPTION FACTOR FOXP3; CXCL10 PROTEIN, MOUSE; CXCL11 PROTEIN, MOUSE; CXCL9 PROTEIN, MOUSE; CXCR3 PROTEIN, MOUSE; ICOS PROTEIN, MOUSE; INTERLEUKIN 2;

ANIMAL CELL; ANTIGEN PRESENTING CELL; ARTICLE; AUTOREGULATION; CELL HOMING; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DENDRITIC CELL; IMMUNOREGULATION; IMPAIRED GLUCOSE TOLERANCE; IN VITRO STUDY; LYMPH NODE; LYMPHOCYTE MIGRATION; NONHUMAN; PANCREAS ISLET BETA CELL; PANCREATITIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; RECEPTOR UPREGULATION; REGULATORY T LYMPHOCYTE; T LYMPHOCYTE SUBPOPULATION; TH1 CELL; ADOPTIVE TRANSFER; ANIMAL; AUTOIMMUNITY; BIOSYNTHESIS; CELL MOTION; DEFICIENCY; IMMUNOLOGY; INSULIN DEPENDENT DIABETES MELLITUS; METABOLISM; MOUSE; NONOBESE DIABETIC MOUSE; SECRETION (PROCESS); TRANSGENIC MOUSE; TRANSPLANTATION;

MUS;

ADOPTIVE TRANSFER; ANIMALS; AUTOIMMUNITY; CELL MOVEMENT; CHEMOKINE CXCL10; CHEMOKINE CXCL11; CHEMOKINE CXCL9; DIABETES MELLITUS, TYPE 1; INDUCIBLE T-CELL CO-STIMULATOR PROTEIN; INSULIN-SECRETING CELLS; INTERFERON-GAMMA; INTERLEUKIN-2; MICE; MICE, INBRED NOD; MICE, TRANSGENIC; PREDIABETIC STATE; RECEPTORS, CXCR3; T-LYMPHOCYTES, REGULATORY; TH1 CELLS;

EID: 84929120250     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0126311     Document Type: Article

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