메뉴 건너뛰기




Volumn 10, Issue 3, 2015, Pages

Identifying prognostic features by bottom-up approach and correlating to drug repositioning

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ANALYTIC METHOD; ARTICLE; BOTTOM UP METHOD; CANCER PROGNOSIS; CANCER RECURRENCE; CANCER STAGING; CANCER SURVIVAL; DISEASE ASSOCIATION; DRUG REPOSITIONING; FEMALE; GENE CLUSTER; GENE EXPRESSION; GENETIC CORRELATION; HUMAN; LIVER CELL CARCINOMA; MAJOR CLINICAL STUDY; MALE; OVERALL SURVIVAL; PROTEIN PROTEIN INTERACTION; RECURRENCE FREE SURVIVAL; SEX DIFFERENCE; SURVIVAL TIME; BIOLOGY; CARCINOMA, HEPATOCELLULAR; CLUSTER ANALYSIS; COHORT ANALYSIS; GENE EXPRESSION PROFILING; GENE REGULATORY NETWORK; GENETICS; LIVER NEOPLASMS; METABOLISM; MIDDLE AGED; PROCEDURES; PROGNOSIS; SURVIVAL ANALYSIS;

EID: 84928978619     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0118672     Document Type: Article
Times cited : (11)

References (57)
  • 1
    • 80053088189 scopus 로고    scopus 로고
    • Hepatocellular carcinoma
    • PMID: 21992124
    • El-Serag HB (2011) Hepatocellular carcinoma. N Engl J Med 365: 1118-1127. doi: 10.1056/NEJMra1001683 PMID: 21992124
    • (2011) N Engl J Med , vol.365 , pp. 1118-1127
    • El-Serag, H.B.1
  • 2
    • 84858658381 scopus 로고    scopus 로고
    • EASL-EORTC clinical practice guidelines: Management of hepatocellular carcinoma
    • PMID: 22424438
    • European Association For The Study Of The L, European Organisation For R, Treatment Of C (2012) EASL-EORTC clinical practice guidelines: management of hepatocellular carcinoma. J Hepatol 56: 908-943. doi: 10.1016/j.jhep.2011.12.001 PMID: 22424438
    • (2012) J Hepatol , vol.56 , pp. 908-943
    • European Association For The Study Of The L1    European Organisation For R2    Treatment Of C3
  • 3
    • 0038748320 scopus 로고    scopus 로고
    • Prognostic staging system for hepatocellular carcinoma (CLIP score): Its value and limitations, and a proposal for a new staging system, the Japan Integrated Staging Score (JIS score)
    • PMID: 12673442
    • Kudo M, Chung H, Osaki Y (2003) Prognostic staging system for hepatocellular carcinoma (CLIP score): its value and limitations, and a proposal for a new staging system, the Japan Integrated Staging Score (JIS score). J Gastroenterol 38: 207-215. PMID: 12673442
    • (2003) J Gastroenterol , vol.38 , pp. 207-215
    • Kudo, M.1    Chung, H.2    Osaki, Y.3
  • 4
    • 0037086560 scopus 로고    scopus 로고
    • Construction of the Chinese University Prognostic Index for hepatocellular carcinoma and comparison with the TNM staging system, the Okuda staging system, and the Cancer of the Liver Italian Program staging system: A study based on 926 patients
    • PMID: 11920539
    • Leung TW, Tang AM, Zee B, Lau WY, Lai PB, et al. (2002) Construction of the Chinese University Prognostic Index for hepatocellular carcinoma and comparison with the TNM staging system, the Okuda staging system, and the Cancer of the Liver Italian Program staging system: a study based on 926 patients. Cancer 94: 1760-1769. PMID: 11920539
    • (2002) Cancer , vol.94 , pp. 1760-1769
    • Leung, T.W.1    Tang, A.M.2    Zee, B.3    Lau, W.Y.4    Lai, P.B.5
  • 5
    • 0032879468 scopus 로고    scopus 로고
    • Prognosis of hepatocellular carcinoma: The BCLC staging classification
    • PMID: 10518312
    • Llovet JM, Bru C, Bruix J (1999) Prognosis of hepatocellular carcinoma: the BCLC staging classification. Semin Liver Dis 19: 329-338. PMID: 10518312
    • (1999) Semin Liver Dis , vol.19 , pp. 329-338
    • Llovet, J.M.1    Bru, C.2    Bruix, J.3
  • 6
    • 0031782818 scopus 로고    scopus 로고
    • A new prognostic system for hepatocellular carcinoma: A retrospective study of 435 patients: The Cancer of the Liver Italian Program (CLIP) investigators
    • PMID: 9731568
    • (1998) A new prognostic system for hepatocellular carcinoma: a retrospective study of 435 patients: the Cancer of the Liver Italian Program (CLIP) investigators. Hepatology 28: 751-755. PMID: 9731568
    • (1998) Hepatology , vol.28 , pp. 751-755
  • 7
    • 0021965806 scopus 로고
    • Natural history of hepatocellular carcinoma and prognosis in relation to treatment. Study of 850 patients
    • PMID: 2990661
    • Okuda K, Ohtsuki T, Obata H, Tomimatsu M, Okazaki N, Hasegawa H, et al. (1985) Natural history of hepatocellular carcinoma and prognosis in relation to treatment. Study of 850 patients. Cancer 56: 918-928. PMID: 2990661
    • (1985) Cancer , vol.56 , pp. 918-928
    • Okuda, K.1    Ohtsuki, T.2    Obata, H.3    Tomimatsu, M.4    Okazaki, N.5    Hasegawa, H.6
  • 8
    • 84856513068 scopus 로고    scopus 로고
    • Mitotic checkpoints and chromosome instability are strong predictors of clinical outcome in gastrointestinal stromal tumors
    • PMID: 22167411
    • Lagarde P, Perot G, Kauffmann A, Brulard C, Dapremont V, et al. (2012) Mitotic checkpoints and chromosome instability are strong predictors of clinical outcome in gastrointestinal stromal tumors. Clin Cancer Res 18: 826-838. doi: 10.1158/1078-0432.CCR-11-1610 PMID: 22167411
    • (2012) Clin Cancer Res , vol.18 , pp. 826-838
    • Lagarde, P.1    Perot, G.2    Kauffmann, A.3    Brulard, C.4    Dapremont, V.5
  • 9
    • 57349090407 scopus 로고    scopus 로고
    • Gene expression in fixed tissues and outcome in hepatocellular carcinoma
    • PMID: 18923165
    • Hoshida Y, Villanueva A, Kobayashi M, Peix J, Chiang DY, et al. (2008) Gene expression in fixed tissues and outcome in hepatocellular carcinoma. N Engl J Med 359: 1995-2004. doi: 10.1056/NEJMoa0804525 PMID: 18923165
    • (2008) N Engl J Med , vol.359 , pp. 1995-2004
    • Hoshida, Y.1    Villanueva, A.2    Kobayashi, M.3    Peix, J.4    Chiang, D.Y.5
  • 10
    • 33748286796 scopus 로고    scopus 로고
    • A signature of chromosomal instability inferred from gene expression profiles predicts clinical outcome in multiple human cancers
    • PMID: 16921376
    • Carter SL, Eklund AC, Kohane IS, Harris LN, Szallasi Z (2006) A signature of chromosomal instability inferred from gene expression profiles predicts clinical outcome in multiple human cancers. Nat Genet 38: 1043-1048. PMID: 16921376
    • (2006) Nat Genet , vol.38 , pp. 1043-1048
    • Carter, S.L.1    Eklund, A.C.2    Kohane, I.S.3    Harris, L.N.4    Szallasi, Z.5
  • 11
    • 18244409687 scopus 로고    scopus 로고
    • Gene expression profiling predicts clinical outcome of breast cancer
    • PMID: 11823860
    • van 't Veer LJ, Dai H, van de Vijver MJ, He YD, Hart AA, et al. (2002) Gene expression profiling predicts clinical outcome of breast cancer. Nature 415: 530-536. PMID: 11823860
    • (2002) Nature , vol.415 , pp. 530-536
    • Van 'T Veer, L.J.1    Dai, H.2    Van De Vijver, M.J.3    He, Y.D.4    Hart, A.A.5
  • 12
    • 84879465430 scopus 로고    scopus 로고
    • A hepatocellular carcinoma 5-gene score associated with survival of patients after liver resection
    • PMID: 23567350
    • Nault JC, De Reynies A, Villanueva A, Calderaro J, Rebouissou S, et al. (2013) A hepatocellular carcinoma 5-gene score associated with survival of patients after liver resection. Gastroenterology 145: 176-187. doi: 10.1053/j.gastro.2013.03.051 PMID: 23567350
    • (2013) Gastroenterology , vol.145 , pp. 176-187
    • Nault, J.C.1    De Reynies, A.2    Villanueva, A.3    Calderaro, J.4    Rebouissou, S.5
  • 13
    • 84862808163 scopus 로고    scopus 로고
    • Sixty-five gene-based risk score classifier predicts overall survival in hepatocellular carcinoma
    • PMID: 22105560
    • Kim SM, Leem SH, Chu IS, Park YY, Kim SC, et al. (2012) Sixty-five gene-based risk score classifier predicts overall survival in hepatocellular carcinoma. Hepatology 55: 1443-1452. doi: 10.1002/hep.24813 PMID: 22105560
    • (2012) Hepatology , vol.55 , pp. 1443-1452
    • Kim, S.M.1    Leem, S.H.2    Chu, I.S.3    Park, Y.Y.4    Kim, S.C.5
  • 14
    • 78650361904 scopus 로고    scopus 로고
    • A unique metastasis gene signature enables prediction of tumor relapse in early-stage hepatocellular carcinoma patients
    • PMID: 21159642
    • Roessler S, Jia HL, Budhu A, Forgues M, Ye QH, et al. (2010) A unique metastasis gene signature enables prediction of tumor relapse in early-stage hepatocellular carcinoma patients. Cancer Res 70: 10202-10212. doi: 10.1158/0008-5472.CAN-10-2607 PMID: 21159642
    • (2010) Cancer Res , vol.70 , pp. 10202-10212
    • Roessler, S.1    Jia, H.L.2    Budhu, A.3    Forgues, M.4    Ye, Q.H.5
  • 15
    • 84899889175 scopus 로고    scopus 로고
    • Robust prognostic gene expression signatures in bladder cancer and lung adenocarcinoma depend on cell cycle related genes
    • PMID: 24465512
    • Dancik GM, Theodorescu D (2014) Robust prognostic gene expression signatures in bladder cancer and lung adenocarcinoma depend on cell cycle related genes. PLoS One 9: e85249. doi: 10.1371/journal.pone.0085249 PMID: 24465512
    • (2014) PLoS One , vol.9 , pp. e85249
    • Dancik, G.M.1    Theodorescu, D.2
  • 16
    • 84892548159 scopus 로고    scopus 로고
    • Prognostic value of a nine-gene signature in glioma patients based on mRNA expression profiling
    • PMID: 24279471
    • Bao ZS, Li MY, Wang JY, Zhang CB, Wang HJ, et al. (2014) Prognostic value of a nine-gene signature in glioma patients based on mRNA expression profiling. CNS Neurosci Ther 20: 112-118. doi: 10.1111/cns.12171 PMID: 24279471
    • (2014) CNS Neurosci Ther , vol.20 , pp. 112-118
    • Bao, Z.S.1    Li, M.Y.2    Wang, J.Y.3    Zhang, C.B.4    Wang, H.J.5
  • 17
    • 84876978905 scopus 로고    scopus 로고
    • Machine learning approach for the outcome prediction of temporal lobe epilepsy surgery
    • PMID: 23646148
    • Armananzas R, Alonso-Nanclares L, Defelipe-Oroquieta J, Kastanauskaite A, de Sola RG, et al. (2013) Machine learning approach for the outcome prediction of temporal lobe epilepsy surgery. PLoS One 8: e62819. doi: 10.1371/journal.pone.0062819 PMID: 23646148
    • (2013) PLoS One , vol.8 , pp. e62819
    • Armananzas, R.1    Alonso-Nanclares, L.2    Defelipe-Oroquieta, J.3    Kastanauskaite, A.4    De Sola, R.G.5
  • 18
    • 84864190709 scopus 로고    scopus 로고
    • A network-based gene expression signature informs prognosis and treatment for colorectal cancer patients
    • PMID: 22844451
    • Shi M, Beauchamp RD, Zhang B (2012) A network-based gene expression signature informs prognosis and treatment for colorectal cancer patients. PLoS One 7: e41292. doi: 10.1371/journal.pone.0041292 PMID: 22844451
    • (2012) PLoS One , vol.7 , pp. e41292
    • Shi, M.1    Beauchamp, R.D.2    Zhang, B.3
  • 19
    • 77950670673 scopus 로고    scopus 로고
    • Gene expression in nontumoral liver tissue and recurrence-free survival in hepatitis C virus-positive hepatocellular carcinoma
    • PMID: 20380719
    • Tsuchiya M, Parker JS, Kono H, Matsuda M, Fujii H, Rusyn I (2010) Gene expression in nontumoral liver tissue and recurrence-free survival in hepatitis C virus-positive hepatocellular carcinoma. Mol Cancer 9: 74. doi: 10.1186/1476-4598-9-74 PMID: 20380719
    • (2010) Mol Cancer , vol.9 , pp. 74
    • Tsuchiya, M.1    Parker, J.S.2    Kono, H.3    Matsuda, M.4    Fujii, H.5    Rusyn, I.6
  • 20
    • 84894288992 scopus 로고    scopus 로고
    • Genetics of rheumatoid arthritis contributes to biology and drug discovery
    • PMID: 24390342
    • Okada Y, Wu D, Trynka G, Raj T, Terao C, et al. (2014) Genetics of rheumatoid arthritis contributes to biology and drug discovery. Nature 506: 376-381. doi: 10.1038/nature12873 PMID: 24390342
    • (2014) Nature , vol.506 , pp. 376-381
    • Okada, Y.1    Wu, D.2    Trynka, G.3    Raj, T.4    Terao, C.5
  • 21
    • 84859638338 scopus 로고    scopus 로고
    • Use of genome-wide association studies for drug repositioning
    • PMID: 22491277
    • Sanseau P, Agarwal P, Barnes MR, Pastinen T, Richards JB, et al. (2012) Use of genome-wide association studies for drug repositioning. Nat Biotechnol 30: 317-320. doi: 10.1038/nbt.2151 PMID: 22491277
    • (2012) Nat Biotechnol , vol.30 , pp. 317-320
    • Sanseau, P.1    Agarwal, P.2    Barnes, M.R.3    Pastinen, T.4    Richards, J.B.5
  • 22
    • 0035942271 scopus 로고    scopus 로고
    • Significance analysis of microarrays applied to the ionizing radiation response
    • PMID: 11309499
    • Tusher VG, Tibshirani R, Chu G (2001) Significance analysis of microarrays applied to the ionizing radiation response. Proc Natl Acad Sci U S A 98: 5116-5121. PMID: 11309499
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 5116-5121
    • Tusher, V.G.1    Tibshirani, R.2    Chu, G.3
  • 23
    • 19344375744 scopus 로고    scopus 로고
    • Semi-supervised methods to predict patient survival from gene expression data
    • PMID: 15094809
    • Bair E, Tibshirani R (2004) Semi-supervised methods to predict patient survival from gene expression data. PLoS Biol 2: E108. PMID: 15094809
    • (2004) PLoS Biol , vol.2 , pp. E108
    • Bair, E.1    Tibshirani, R.2
  • 24
    • 0000336139 scopus 로고
    • Regression models and life tables
    • Cox DR (1972) Regression models and life tables. JR stat soc B 34: 187-220.
    • (1972) JR Stat Soc B , vol.34 , pp. 187-220
    • Cox, D.R.1
  • 25
    • 84865730611 scopus 로고
    • A set of measures of centrality based on betweenness
    • Freeman LC (1977) A set of measures of centrality based on betweenness. Sociometry: 35-41.
    • (1977) Sociometry , pp. 35-41
    • Freeman, L.C.1
  • 27
    • 77956381678 scopus 로고    scopus 로고
    • Construction and analysis of protein-protein interaction networks
    • PMID: 20334628
    • Raman K (2010) Construction and analysis of protein-protein interaction networks. Autom Exp 2: 2. doi: 10.1186/1759-4499-2-2 PMID: 20334628
    • (2010) Autom Exp , vol.2 , pp. 2
    • Raman, K.1
  • 28
    • 44449119819 scopus 로고    scopus 로고
    • A protein interaction network associated with asthma
    • PMID: 18395227
    • Hwang S, Son SW, Kim SC, Kim YJ, Jeong H, Lee D (2008) A protein interaction network associated with asthma. J Theor Biol 252: 722-731. doi: 10.1016/j.jtbi.2008.02.011 PMID: 18395227
    • (2008) J Theor Biol , vol.252 , pp. 722-731
    • Hwang, S.1    Son, S.W.2    Kim, S.C.3    Kim, Y.J.4    Jeong, H.5    Lee, D.6
  • 29
    • 0242490780 scopus 로고    scopus 로고
    • Cytoscape: A software environment for integrated models of biomolecular interaction networks
    • PMID: 14597658
    • Shannon P, Markiel A, Ozier O, Baliga NS, Wang JT, et al. (2003) Cytoscape: a software environment for integrated models of biomolecular interaction networks. Genome research 13: 2498-2504. PMID: 14597658
    • (2003) Genome Research , vol.13 , pp. 2498-2504
    • Shannon, P.1    Markiel, A.2    Ozier, O.3    Baliga, N.S.4    Wang, J.T.5
  • 32
    • 84944178665 scopus 로고
    • Hierarchical grouping to optimize an objective function
    • Ward JH Jr (1963) Hierarchical grouping to optimize an objective function. Journal of the American statistical association 58: 236-244.
    • (1963) Journal of the American Statistical Association , vol.58 , pp. 236-244
    • Ward, J.H.1
  • 33
    • 77649193013 scopus 로고    scopus 로고
    • Immune infiltration in human tumors: A prognostic factor that should not be ignored
    • PMID: 19946335
    • Pages F, Galon J, Dieu-Nosjean MC, Tartour E, Sautes-Fridman C, et al. (2010) Immune infiltration in human tumors: a prognostic factor that should not be ignored. Oncogene 29: 1093-1102. doi: 10.1038/onc.2009.416 PMID: 19946335
    • (2010) Oncogene , vol.29 , pp. 1093-1102
    • Pages, F.1    Galon, J.2    Dieu-Nosjean, M.C.3    Tartour, E.4    Sautes-Fridman, C.5
  • 34
    • 84859267371 scopus 로고    scopus 로고
    • Therapeutic target database update 2012: A resource for facilitating target-oriented drug discovery
    • PMID: 21948793
    • Zhu F, Shi Z, Qin C, Tao L, Liu X, et al. (2012) Therapeutic target database update 2012: a resource for facilitating target-oriented drug discovery. Nucleic Acids Res 40: D1128-1136. doi: 10.1093/nar/gkr797 PMID: 21948793
    • (2012) Nucleic Acids Res , vol.40 , pp. D1128-D1136
    • Zhu, F.1    Shi, Z.2    Qin, C.3    Tao, L.4    Liu, X.5
  • 35
    • 78651287426 scopus 로고    scopus 로고
    • DrugBank 3.0: A comprehensive resource for 'omics' research on drugs
    • PMID: 21059682
    • Knox C, Law V, Jewison T, Liu P, Ly S, et al. (2011) DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Nucleic Acids Res 39: D1035-1041. doi: 10.1093/nar/gkq1126 PMID: 21059682
    • (2011) Nucleic Acids Res , vol.39 , pp. D1035-D1041
    • Knox, C.1    Law, V.2    Jewison, T.3    Liu, P.4    Ly, S.5
  • 36
    • 84878787217 scopus 로고    scopus 로고
    • Differential combinatorial regulatory network analysis related to venous metastasis of hepatocellular carcinoma
    • PMID: 23282077
    • Zeng L, Yu J, Huang T, Jia H, Dong Q, et al. (2012) Differential combinatorial regulatory network analysis related to venous metastasis of hepatocellular carcinoma. BMC Genomics 13 Suppl 8: S14. doi: 10.1186/1471-2164-13-S8-S14 PMID: 23282077
    • (2012) BMC Genomics , vol.13 , pp. S14
    • Zeng, L.1    Yu, J.2    Huang, T.3    Jia, H.4    Dong, Q.5
  • 37
    • 84904037894 scopus 로고    scopus 로고
    • Application of microRNA and mRNA expression profiling on prognostic biomarker discovery for hepatocellular carcinoma
    • PMID: 24564407
    • Wei L, Lian B, Zhang Y, Li W, Gu J, et al. (2014) Application of microRNA and mRNA expression profiling on prognostic biomarker discovery for hepatocellular carcinoma. BMC Genomics 15 Suppl 1: S13. doi: 10.1186/1471-2164-15-S1-S13 PMID: 24564407
    • (2014) BMC Genomics , vol.15 , pp. S13
    • Wei, L.1    Lian, B.2    Zhang, Y.3    Li, W.4    Gu, J.5
  • 38
    • 84875338016 scopus 로고    scopus 로고
    • Insulin-like growth factor-1 genotypes and haplotypes influence the survival of prostate cancer patients with bone metastasis at initial diagnosis
    • PMID: 23530598
    • Tsuchiya N, Narita S, Inoue T, Saito M, Numakura K, et al. (2013) Insulin-like growth factor-1 genotypes and haplotypes influence the survival of prostate cancer patients with bone metastasis at initial diagnosis. BMC Cancer 13: 150. doi: 10.1186/1471-2407-13-150 PMID: 23530598
    • (2013) BMC Cancer , vol.13 , pp. 150
    • Tsuchiya, N.1    Narita, S.2    Inoue, T.3    Saito, M.4    Numakura, K.5
  • 39
    • 84881248238 scopus 로고    scopus 로고
    • Serum insulin-like growth factor-I level is an independent predictor of recurrence and survival in early hepatocellular carcinoma: A prospective cohort study
    • PMID: 23757355
    • Cho EJ, Lee JH, Yoo JJ, Choi WM, Lee MJ, et al. (2013) Serum insulin-like growth factor-I level is an independent predictor of recurrence and survival in early hepatocellular carcinoma: a prospective cohort study. Clin Cancer Res 19: 4218-4227. doi: 10.1158/1078-0432.CCR-12-3443 PMID: 23757355
    • (2013) Clin Cancer Res , vol.19 , pp. 4218-4227
    • Cho, E.J.1    Lee, J.H.2    Yoo, J.J.3    Choi, W.M.4    Lee, M.J.5
  • 40
    • 4544273428 scopus 로고    scopus 로고
    • Classification and prediction of survival in hepatocellular carcinoma by gene expression profiling
    • PMID: 15349906
    • Lee JS, Chu IS, Heo J, Calvisi DF, Sun Z, et al. (2004) Classification and prediction of survival in hepatocellular carcinoma by gene expression profiling. Hepatology 40: 667-676. PMID: 15349906
    • (2004) Hepatology , vol.40 , pp. 667-676
    • Lee, J.S.1    Chu, I.S.2    Heo, J.3    Calvisi, D.F.4    Sun, Z.5
  • 41
    • 84901390396 scopus 로고    scopus 로고
    • Autophagy enhances hepatocellular carcinoma progression by activation of mitochondrial beta-oxidation
    • Toshima T, Shirabe K, Matsumoto Y, Yoshiya S, Ikegami T, et al. (2013) Autophagy enhances hepatocellular carcinoma progression by activation of mitochondrial beta-oxidation. J Gastroenterol.
    • (2013) J Gastroenterol
    • Toshima, T.1    Shirabe, K.2    Matsumoto, Y.3    Yoshiya, S.4    Ikegami, T.5
  • 42
    • 77952731389 scopus 로고    scopus 로고
    • Inhibitory role of peroxisome proliferator-activated receptor gamma in hepatocarcinogenesis in mice and in vitro
    • PMID: 20512989
    • Yu J, Shen B, Chu ES, Teoh N, Cheung KF, et al. (2010) Inhibitory role of peroxisome proliferator-activated receptor gamma in hepatocarcinogenesis in mice and in vitro. Hepatology 51: 2008-2019. doi: 10.1002/hep.23550 PMID: 20512989
    • (2010) Hepatology , vol.51 , pp. 2008-2019
    • Yu, J.1    Shen, B.2    Chu, E.S.3    Teoh, N.4    Cheung, K.F.5
  • 43
    • 20144389197 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma inhibition prevents adhesion to the extracellular matrix and induces anoikis in hepatocellular carcinoma cells
    • PMID: 15781638
    • Schaefer KL, Wada K, Takahashi H, Matsuhashi N, Ohnishi S, et al. (2005) Peroxisome proliferator-activated receptor gamma inhibition prevents adhesion to the extracellular matrix and induces anoikis in hepatocellular carcinoma cells. Cancer Res 65: 2251-2259. PMID: 15781638
    • (2005) Cancer Res , vol.65 , pp. 2251-2259
    • Schaefer, K.L.1    Wada, K.2    Takahashi, H.3    Matsuhashi, N.4    Ohnishi, S.5
  • 44
    • 79959703984 scopus 로고    scopus 로고
    • Epidermal Growth Factor Receptor (EGFR) Crosstalks in Liver Cancer
    • PMID: 24212818
    • Berasain C, Ujue Latasa M, Urtasun R, Goni S, Elizalde M, et al. (2011) Epidermal Growth Factor Receptor (EGFR) Crosstalks in Liver Cancer. Cancers (Basel) 3: 2444-2461. doi: 10.3390/cancers3022444 PMID: 24212818
    • (2011) Cancers (Basel) , vol.3 , pp. 2444-2461
    • Berasain, C.1    Ujue Latasa, M.2    Urtasun, R.3    Goni, S.4    Elizalde, M.5
  • 45
    • 33745888428 scopus 로고    scopus 로고
    • Dissemination of hepatocellular carcinoma is mediated via chemokine receptor CXCR4
    • PMID: 16819541
    • Schimanski CC, Bahre R, Gockel I, Muller A, Frerichs K, et al. (2006) Dissemination of hepatocellular carcinoma is mediated via chemokine receptor CXCR4. Br J Cancer 95: 210-217. PMID: 16819541
    • (2006) Br J Cancer , vol.95 , pp. 210-217
    • Schimanski, C.C.1    Bahre, R.2    Gockel, I.3    Muller, A.4    Frerichs, K.5
  • 46
    • 63849150544 scopus 로고    scopus 로고
    • Roles of chemokine receptor 4 (CXCR4) and chemokine ligand 12 (CXCL12) in metastasis of hepatocellular carcinoma cells
    • PMID: 18954561
    • Liu H, Pan Z, Li A, Fu S, Lei Y, et al. (2008) Roles of chemokine receptor 4 (CXCR4) and chemokine ligand 12 (CXCL12) in metastasis of hepatocellular carcinoma cells. Cell Mol Immunol 5: 373-378. doi: 10.1038/cmi.2008.46 PMID: 18954561
    • (2008) Cell Mol Immunol , vol.5 , pp. 373-378
    • Liu, H.1    Pan, Z.2    Li, A.3    Fu, S.4    Lei, Y.5
  • 47
    • 20244373050 scopus 로고    scopus 로고
    • Hepatic gene expression profiles associated with fibrosis progression and hepatocarcinogenesis in hepatitis C patients
    • PMID: 15800993
    • Shao RX, Hoshida Y, Otsuka M, Kato N, Tateishi R, et al. (2005) Hepatic gene expression profiles associated with fibrosis progression and hepatocarcinogenesis in hepatitis C patients. World J Gastroenterol 11: 1995-1999. PMID: 15800993
    • (2005) World J Gastroenterol , vol.11 , pp. 1995-1999
    • Shao, R.X.1    Hoshida, Y.2    Otsuka, M.3    Kato, N.4    Tateishi, R.5
  • 48
    • 84903770490 scopus 로고    scopus 로고
    • Integrated analysis of mutation data from various sources identifies key genes and signaling pathways in hepatocellular carcinoma
    • PMID: 24988079
    • Zhang Y, Qiu Z, Wei L, Tang R, Lian B, et al. (2014) Integrated analysis of mutation data from various sources identifies key genes and signaling pathways in hepatocellular carcinoma. PLoS One 9: e100854. doi: 10.1371/journal.pone.0100854 PMID: 24988079
    • (2014) PLoS One , vol.9 , pp. e100854
    • Zhang, Y.1    Qiu, Z.2    Wei, L.3    Tang, R.4    Lian, B.5
  • 49
    • 20544452357 scopus 로고    scopus 로고
    • Mechanical stretch induces monocyte chemoattractant activity via an NF-kappaB-dependent monocyte chemoattractant protein-1-mediated pathway in human mesangial cells: Inhibition by rosiglitazone
    • PMID: 15677312
    • Gruden G, Setti G, Hayward A, Sugden D, Duggan S, et al. (2005) Mechanical stretch induces monocyte chemoattractant activity via an NF-kappaB-dependent monocyte chemoattractant protein-1-mediated pathway in human mesangial cells: inhibition by rosiglitazone. J Am Soc Nephrol 16: 688-696. PMID: 15677312
    • (2005) J Am Soc Nephrol , vol.16 , pp. 688-696
    • Gruden, G.1    Setti, G.2    Hayward, A.3    Sugden, D.4    Duggan, S.5
  • 50
  • 51
    • 0034772516 scopus 로고    scopus 로고
    • Sulfasalazine, a potent suppressor of lymphoma growth by inhibition of the x(c)- cystine transporter: A new action for an old drug
    • PMID: 11587223
    • Gout PW, Buckley AR, Simms CR, Bruchovsky N (2001) Sulfasalazine, a potent suppressor of lymphoma growth by inhibition of the x(c)- cystine transporter: a new action for an old drug. Leukemia 15: 1633-1640. PMID: 11587223
    • (2001) Leukemia , vol.15 , pp. 1633-1640
    • Gout, P.W.1    Buckley, A.R.2    Simms, C.R.3    Bruchovsky, N.4
  • 52
    • 33846628923 scopus 로고    scopus 로고
    • Sulfasalazine-induced cystine starvation: Potential use for prostate cancer therapy
    • PMID: 17075799
    • Doxsee DW, Gout PW, Kurita T, Lo M, Buckley AR, et al. (2007) Sulfasalazine-induced cystine starvation: potential use for prostate cancer therapy. Prostate 67: 162-171. PMID: 17075799
    • (2007) Prostate , vol.67 , pp. 162-171
    • Doxsee, D.W.1    Gout, P.W.2    Kurita, T.3    Lo, M.4    Buckley, A.R.5
  • 53
    • 48749090567 scopus 로고    scopus 로고
    • Telmisartan is a potent target for prevention and treatment in human prostate cancer
    • PMID: 18636189
    • Funao K, Matsuyama M, Kawahito Y, Sano H, Chargui J, et al. (2008) Telmisartan is a potent target for prevention and treatment in human prostate cancer. Oncol Rep 20: 295-300. PMID: 18636189
    • (2008) Oncol Rep , vol.20 , pp. 295-300
    • Funao, K.1    Matsuyama, M.2    Kawahito, Y.3    Sano, H.4    Chargui, J.5
  • 54
    • 77955511761 scopus 로고    scopus 로고
    • UGT1A and TYMS genetic variants predict toxicity and response of colorectal cancer patients treated with first-line irinotecan and fluorouracil combination therapy
    • PMID: 20628391
    • Martinez-Balibrea E, Abad A, Martinez-Cardus A, Gines A, Valladares M, et al. (2010) UGT1A and TYMS genetic variants predict toxicity and response of colorectal cancer patients treated with first-line irinotecan and fluorouracil combination therapy. Br J Cancer 103: 581-589. doi: 10.1038/sj.bjc.6605776 PMID: 20628391
    • (2010) Br J Cancer , vol.103 , pp. 581-589
    • Martinez-Balibrea, E.1    Abad, A.2    Martinez-Cardus, A.3    Gines, A.4    Valladares, M.5
  • 55
    • 40749113642 scopus 로고    scopus 로고
    • Alcohol, cofactors and the genetics of hepatocellular carcinoma
    • PMID: 18336674
    • Yu MC, Yuan JM, Lu SC (2008) Alcohol, cofactors and the genetics of hepatocellular carcinoma. J Gastroenterol Hepatol 23 Suppl 1: S92-97. doi: 10.1111/j.1440-1746.2007.05293.x PMID: 18336674
    • (2008) J Gastroenterol Hepatol , vol.23 , pp. S92-S97
    • Yu, M.C.1    Yuan, J.M.2    Lu, S.C.3
  • 56
    • 34548804362 scopus 로고    scopus 로고
    • Genetic polymorphisms in the methylenetetrahydrofolate reductase and thymidylate synthase genes and risk of hepatocellular carcinoma
    • PMID: 17659576
    • Yuan JM, Lu SC, Van Den Berg D, Govindarajan S, Zhang ZQ, et al. (2007) Genetic polymorphisms in the methylenetetrahydrofolate reductase and thymidylate synthase genes and risk of hepatocellular carcinoma. Hepatology 46: 749-758. PMID: 17659576
    • (2007) Hepatology , vol.46 , pp. 749-758
    • Yuan, J.M.1    Lu, S.C.2    Van Den Berg, D.3    Govindarajan, S.4    Zhang, Z.Q.5
  • 57
    • 33947495362 scopus 로고    scopus 로고
    • Gemcitabine plus oxaliplatin (GEMOX) in patients with advanced hepatocellular carcinoma (HCC): Results of a phase II study
    • PMID: 17330837
    • Louafi S, Boige V, Ducreux M, Bonyhay L, Mansourbakht T, et al. (2007) Gemcitabine plus oxaliplatin (GEMOX) in patients with advanced hepatocellular carcinoma (HCC): results of a phase II study. Cancer 109: 1384-1390. PMID: 17330837
    • (2007) Cancer , vol.109 , pp. 1384-1390
    • Louafi, S.1    Boige, V.2    Ducreux, M.3    Bonyhay, L.4    Mansourbakht, T.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.