Hepatic gene expression profiles associated with fibrosis progression and hepatocarcinogenesis in hepatitis C patients

World Journal of Gastroenterology

Volumn 11, Issue 13, 2005, Pages 1995-1999

  Shao, Run Xuan ^a   Hoshida, Yujin ^a   Otsuka, Motoyuki ^a   Kato, Naoya ^a   Tateishi, Ryosuke ^a   Teratani, Takuma ^a   Shiina, Shuichiro ^a   Taniguchi, Hiroyoshi ^a   Moriyama, Masaru ^a   Kawabe, Takao ^a   Omata, Masao ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

Hepatitis C; Hepatocellular carcinoma; Oligonucleotide microarray

Indexed keywords

ALBUMIN; APOLIPOPROTEIN; CELL CYCLE PROTEIN; CHEMOKINE RECEPTOR CCR7; CYTOCHROME P450; DRUG METABOLIZING ENZYME; GLUCOSIDASE; INTERFERON; ONCOPROTEIN; PLASMA PROTEIN; PROTEIN SERINE THREONINE KINASE; TUMOR NECROSIS FACTOR;

ADULT; AGED; ARTICLE; CARBOHYDRATE METABOLISM; CARCINOGENESIS; CELL CYCLE; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; DNA MICROARRAY; FEMALE; GENE EXPRESSION; GENE IDENTIFICATION; HEPATITIS C; HEPATITIS C VIRUS; HUMAN; HUMAN TISSUE; IMMUNE RESPONSE; LIVER BIOPSY; LIVER CARCINOGENESIS; LIVER CELL CARCINOMA; LIVER FIBROSIS; MALE; NONHUMAN; RNA EXTRACTION; SIGNAL NOISE RATIO;

EID: 20244373050     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.v11.i13.1995     Document Type: Article

References (14)

1. Yoshida H, Shiratori Y, Moriyama M, Arakawa Y, Ide T, Sata M, Inoue O, Yano M, Tanaka M, Fujiyama S, Nishiguchi S, Kuroki T, Imazeki F, Yokosuka O, Kinoyama S, Yamad G, Omata M. Interferon therapy reduces the risk for hepatocellular carcinoma: national surveillance program of cirrhotic and noncirrhotic patients with chronic hepatitis C in Japan. Ann Intern Med 1999; 131: 174-181
2. Smith MW, Yue ZN, Korth MJ, Do HA, Boix L, Fausto N, Bruix J, Carithers RL Jr, Katze MG. Hepatitis C virus and liver disease: global transcriptional profiling and identification of potential markers. Hepatology 2003; 38: 1458-1467
3. Ji X, Cheung R, Cooper S, Li Q, Greenberg HB, He XS. Interferon alfa regulated gene expression in patients initiating interferon treatment for chronic hepatitis C. Hepatology 2003; 37: 610-621
4. Anders RA, Yerian LM, Tretiakova M, Davison JM, Quigg RJ, Domer PH, Hoberg J, Hart J. cDNA microarray analysis of macroregenerative and dysplastic nodules in end-stage hepatitis C virus-induced cirrhosis. Am J Pathol 2003; 162: 991-1000
5. Sung YK, Hwang SY, Park MK, Farooq M, Han IS, Bae HI, Kim JC, Kim M. Glypican-3 is overexpressed in human hepatocellular carcinoma. Cancer Sci 2003; 94: 259-262
6. Yagyu R, Hamamoto R, Furukawa Y, Okabe H, Yamamura T, Nakamura Y. Isolation and characterization of a novel human gene, VANGL1, as a therapeutic target for hepatocellular carcinoma. Int J Oncol 2002; 20: 1173-1178
7. Smith MW, Yue ZN, Geiss GK, Sadovnikova NY, Carter VS, Boix L, Lazaro CA, Rosenberg GB, Bumgarner RE, Fausto N, Bruix J, Katze MG. Identification of novel tumor markers in hepatitis C virus-associated hepatocellular carcinoma. Cancer Res 2003; 63: 859-864
8. Desmet VJ, Gerber M, Hoofnagle JH, Manns M, Scheuer PJ. Classification of chronic hepatitis: diagnosis, grading and staging. Hepatology 1994; 19: 1513-1520
9. Liver Cancer Study Group of Japan. Classification of primary liver cancer. Kanehara & Co., Ltd., Tokyo 1997
10. Shiratori Y, Imazeki F, Moriyama M, Yano M, Arakawa Y, Yokosuka O, Kuroki T, Nishiguchi S, Sata M, Yamada G, Fujiyama S, Yoshida H, Omata M. Histologic improvement of fibrosis in patients with hepatitis C who have sustained response to interferon therapy. Ann Intern Med 2000; 132: 517-524
11. Takano S, Yokosuka O, Imazeki F, Tagawa M, Omata M. Incidence of hepatocellular carcinoma in chronic hepatitis B and C: a prospective study of 251 patients. Hepatology 1995; 21: 650-655
12. Honda M, Kaneko S, Kawai H, Shirota Y, Kobayashi K. Differential gene expression between chronic hepatitis B and C hepatic lesion. Gastroenterology 2001; 120: 955-966
13. Okabe H, Satoh S, Kato T, Kitahara O, Yanagawa R, Yamaoka Y, Tsunoda T, Furukawa Y, Nakamura Y. Genome-wide analysis of gene expression in human hepatocellular carcinomas using cDNA microarray: identification of genes involved in viral carcinogenesis and tumor progression. Cancer Res 2001; 61: 2129-2137
14. Wang Y, Kato N, Hoshida Y, Otsuka M, Taniguchi H, Moriyama M, Shiina S, Kawabe T, Ito YM, Omata M. UDP-glucuronosyltransferase 1A7 genetic polymorphisms are associated with hepatocellular carcinoma in Japanese patients with hepatitis C virus infection. Clin Cancer Res 2004; 10: 2441-2446