메뉴 건너뛰기




Volumn 46, Issue 3, 2007, Pages 749-758

Genetic polymorphisms in the Methylenetetrahydrofolate reductase and Thymidylate synthase genes and risk of hepatocellular carcinoma

Author keywords

[No Author keywords available]

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); THYMIDYLATE SYNTHASE;

EID: 34548804362     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1002/hep.21735     Document Type: Article
Times cited : (76)

References (55)
  • 1
    • 34548718911 scopus 로고    scopus 로고
    • Ferlay J, Bray F, Pisani P, Parkin DM. GLOBOCAN 2002 Cancer Incidence, Mortality and Prevalence Worldwide. IARC CancerBase No. 5, version 2.0 ed. Lyon: IARC Press, 2004
    • Ferlay J, Bray F, Pisani P, Parkin DM. GLOBOCAN 2002 Cancer Incidence, Mortality and Prevalence Worldwide. IARC CancerBase No. 5, version 2.0 ed. Lyon: IARC Press, 2004.
  • 3
    • 0024550770 scopus 로고
    • Hepatitis B virus, aflaroxins, and hepatocellular carcinoma in southern Guangxi, China
    • Yeh FS, Yu MC, Mo CC, Luo S, Tong MJ, Henderson BE. Hepatitis B virus, aflaroxins, and hepatocellular carcinoma in southern Guangxi, China. Cancer Res 1989;49:2506-2509.
    • (1989) Cancer Res , vol.49 , pp. 2506-2509
    • Yeh, F.S.1    Yu, M.C.2    Mo, C.C.3    Luo, S.4    Tong, M.J.5    Henderson, B.E.6
  • 4
    • 0031014425 scopus 로고    scopus 로고
    • The relative roles of hepatitis B and C viruses in the etiology of hepatocellular carcinoma in southern African blacks
    • Kew MC, Yu MC, Kedda MA, Coppin A, Sarkin A, Hodkinson J. The relative roles of hepatitis B and C viruses in the etiology of hepatocellular carcinoma in southern African blacks. Gasrroenterology 1997;112:184-187.
    • (1997) Gasrroenterology , vol.112 , pp. 184-187
    • Kew, M.C.1    Yu, M.C.2    Kedda, M.A.3    Coppin, A.4    Sarkin, A.5    Hodkinson, J.6
  • 5
    • 0032579547 scopus 로고    scopus 로고
    • A meta-analysis of epidemiological studies on the combined effect of hepatitis B and C virus infections in causing hepatocellular carcinoma
    • Donaro F, Boffetta P, Puoti M. A meta-analysis of epidemiological studies on the combined effect of hepatitis B and C virus infections in causing hepatocellular carcinoma. Int J Cancer 1998;75:347-354.
    • (1998) Int J Cancer , vol.75 , pp. 347-354
    • Donaro, F.1    Boffetta, P.2    Puoti, M.3
  • 6
    • 7044260779 scopus 로고    scopus 로고
    • Environmental factors and risk for hepatocellular carcinoma
    • Yu MC, Yuan JM. Environmental factors and risk for hepatocellular carcinoma. Gastroenterology 2004;127:S72-S78.
    • (2004) Gastroenterology , vol.127
    • Yu, M.C.1    Yuan, J.M.2
  • 8
    • 4143065907 scopus 로고    scopus 로고
    • Synergism of alcohol, diabetes, and viral hepatitis on the risk of hepatocellular carcinoma in blacks and whites in the U.S
    • Yuan JM, Govindarajan S, Arakawa K, Yu MC. Synergism of alcohol, diabetes, and viral hepatitis on the risk of hepatocellular carcinoma in blacks and whites in the U.S. Cancer 2004;101:1009-1017.
    • (2004) Cancer , vol.101 , pp. 1009-1017
    • Yuan, J.M.1    Govindarajan, S.2    Arakawa, K.3    Yu, M.C.4
  • 9
    • 0021053494 scopus 로고
    • Hepatocarcinogenesis in rats fed methyl-deficient, amino acid-defined diets
    • Mikol YB, Hoover KL, Creasia D, Poirier LA. Hepatocarcinogenesis in rats fed methyl-deficient, amino acid-defined diets. Carcinogenesis 1983;4:1619-1629.
    • (1983) Carcinogenesis , vol.4 , pp. 1619-1629
    • Mikol, Y.B.1    Hoover, K.L.2    Creasia, D.3    Poirier, L.A.4
  • 10
    • 0026786299 scopus 로고
    • High incidence of hepatocellular carcinomas induced by a choline deficient L-amino acid defined diet in rats
    • Nakae D, Yoshiji H, Mizumoto Y, Horiguchi K, Shiraiwa K, Tamura K, et al. High incidence of hepatocellular carcinomas induced by a choline deficient L-amino acid defined diet in rats. Cancer Res 1992;52:5042-5045.
    • (1992) Cancer Res , vol.52 , pp. 5042-5045
    • Nakae, D.1    Yoshiji, H.2    Mizumoto, Y.3    Horiguchi, K.4    Shiraiwa, K.5    Tamura, K.6
  • 11
    • 0028925741 scopus 로고    scopus 로고
    • Pogribny IP, Basnakian AG, Miller BJ, Loparina NG, Poirier LA, James SJ. Breaks in genomic DNA and within the p53 gene are associated with hypomethylation in livers of folate/methyl-deficient rats. Cancer Res 1995;55:1894-1901.
    • Pogribny IP, Basnakian AG, Miller BJ, Loparina NG, Poirier LA, James SJ. Breaks in genomic DNA and within the p53 gene are associated with hypomethylation in livers of folate/methyl-deficient rats. Cancer Res 1995;55:1894-1901.
  • 12
    • 0031428480 scopus 로고    scopus 로고
    • Presence and consequence of uracil in preneoplastic DNA from folate/methyl-deficient rats
    • Pogribny IP, Muskhelishvili L, Miller BJ, James SJ. Presence and consequence of uracil in preneoplastic DNA from folate/methyl-deficient rats. Carcinogenesis 1997;18:2071-2076.
    • (1997) Carcinogenesis , vol.18 , pp. 2071-2076
    • Pogribny, I.P.1    Muskhelishvili, L.2    Miller, B.J.3    James, S.J.4
  • 13
    • 0031022797 scopus 로고    scopus 로고
    • Folate deficiency in rats induces DNA strand breaks and hypomethylation within the p53 tumor suppressor gene
    • Kim YI, Pogribny IP, Basnakian AG, Miller JW, Selhub J, James SJ, et al. Folate deficiency in rats induces DNA strand breaks and hypomethylation within the p53 tumor suppressor gene. Am J Clin Nutr 1997;65:46-52.
    • (1997) Am J Clin Nutr , vol.65 , pp. 46-52
    • Kim, Y.I.1    Pogribny, I.P.2    Basnakian, A.G.3    Miller, J.W.4    Selhub, J.5    James, S.J.6
  • 14
    • 0021366060 scopus 로고
    • Chromosome breakage induced by thymidylate stress in thymidylate synthase-negative mutants of mouse FM3A cells
    • Hori T, Ayusawa D, Shimizu K, Koyama H, Seno T. Chromosome breakage induced by thymidylate stress in thymidylate synthase-negative mutants of mouse FM3A cells. Cancer Res 1984;44:703-709.
    • (1984) Cancer Res , vol.44 , pp. 703-709
    • Hori, T.1    Ayusawa, D.2    Shimizu, K.3    Koyama, H.4    Seno, T.5
  • 15
    • 0022337996 scopus 로고
    • Expression of fragile site on the human X chromosome in somatic cell hybrids between human fragile X cells and thymidylate synthase-negative mouse mutant cells
    • Hori T, Ayusawa D, Glover TW, Seno T. Expression of fragile site on the human X chromosome in somatic cell hybrids between human fragile X cells and thymidylate synthase-negative mouse mutant cells. Jpn J Cancer Res 1985;76:977-983.
    • (1985) Jpn J Cancer Res , vol.76 , pp. 977-983
    • Hori, T.1    Ayusawa, D.2    Glover, T.W.3    Seno, T.4
  • 16
    • 0023134446 scopus 로고    scopus 로고
    • Kaneda S, Takeishi K, Ayusawa D, Shimizu K, Seno T, Altman S. Role in translation of a triple tandemly repeated sequence in the 5′-untranslated region of human thymidylate synthase mRNA. Nucl Acids Res 1987;15:1259-1270.
    • Kaneda S, Takeishi K, Ayusawa D, Shimizu K, Seno T, Altman S. Role in translation of a triple tandemly repeated sequence in the 5′-untranslated region of human thymidylate synthase mRNA. Nucl Acids Res 1987;15:1259-1270.
  • 17
    • 0033564283 scopus 로고    scopus 로고
    • Ethnic variation in the thymidylate synthase enhancer region polymorphism among Caucasian and Asian populations
    • Marsh S, Collie-Duguid ES, Li T, Liu X, McLeod HL. Ethnic variation in the thymidylate synthase enhancer region polymorphism among Caucasian and Asian populations. Genomics 1999;58:310-312.
    • (1999) Genomics , vol.58 , pp. 310-312
    • Marsh, S.1    Collie-Duguid, E.S.2    Li, T.3    Liu, X.4    McLeod, H.L.5
  • 18
    • 0033427561 scopus 로고    scopus 로고
    • Polymorphic tandem repeats in the thymidylate synthase gene is associated with its protein expression in human gastrointestinal cancers
    • Kawakami K, Omura K, Kanehira E, Watanabe Y. Polymorphic tandem repeats in the thymidylate synthase gene is associated with its protein expression in human gastrointestinal cancers. Anticancer Res 1999;19:3249-3252.
    • (1999) Anticancer Res , vol.19 , pp. 3249-3252
    • Kawakami, K.1    Omura, K.2    Kanehira, E.3    Watanabe, Y.4
  • 19
    • 0034518362 scopus 로고    scopus 로고
    • Searching expressed sequence tag databases: Discovery and confirmation of a common polymorphism in the thymidylate synthase gene
    • Ulrich CM, Bigler J, Velicer CM, Greene EA, Farin FM, Potter JD. Searching expressed sequence tag databases: discovery and confirmation of a common polymorphism in the thymidylate synthase gene. Cancer Epidemiol Biomarkers Prev 2000;9:1381-1385.
    • (2000) Cancer Epidemiol Biomarkers Prev , vol.9 , pp. 1381-1385
    • Ulrich, C.M.1    Bigler, J.2    Velicer, C.M.3    Greene, E.A.4    Farin, F.M.5    Potter, J.D.6
  • 20
    • 2442480694 scopus 로고    scopus 로고
    • A 6 bp polymorphism in the thymidylate synthase gene causes message instability and is associated with decreased intratumoral TS mRNA levels
    • Mandola MV, Stoehlmacher J, Zhang W, Groshen S, Yu MC, Iqbal S, et al. A 6 bp polymorphism in the thymidylate synthase gene causes message instability and is associated with decreased intratumoral TS mRNA levels. Pharmacogenetics 2004;14:319-327.
    • (2004) Pharmacogenetics , vol.14 , pp. 319-327
    • Mandola, M.V.1    Stoehlmacher, J.2    Zhang, W.3    Groshen, S.4    Yu, M.C.5    Iqbal, S.6
  • 21
    • 20244362795 scopus 로고    scopus 로고
    • A common insertion/deletion polymorphism of the thymidylate synthase (TYMS) gene is a determinant of red blood cell folate and homocysteine concentrations
    • Kealey C, Brown KS, Woodside JV, Young I, Murray L, Boreham CA, et al. A common insertion/deletion polymorphism of the thymidylate synthase (TYMS) gene is a determinant of red blood cell folate and homocysteine concentrations. Hum Genet 2005;116:347-353.
    • (2005) Hum Genet , vol.116 , pp. 347-353
    • Kealey, C.1    Brown, K.S.2    Woodside, J.V.3    Young, I.4    Murray, L.5    Boreham, C.A.6
  • 22
    • 23144436179 scopus 로고    scopus 로고
    • Role of methionine adenosyltransferase and S-adenosylmethionine in alcohol-associated liver cancer
    • Lu SC, Mato JM. Role of methionine adenosyltransferase and S-adenosylmethionine in alcohol-associated liver cancer. Alcohol 2005;35:227-234.
    • (2005) Alcohol , vol.35 , pp. 227-234
    • SC, L.1    Mato, J.M.2
  • 23
    • 0029049553 scopus 로고
    • A candidate genetic risk factor for vascular disease: A common mutation in methylenetetrahydrofolate reductase
    • Frosst P, Blom HJ, Milos R, Goyette P, Sheppard CA, Matthews RG, et al. A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase. Nat Genet 1995;10:111-113.
    • (1995) Nat Genet , vol.10 , pp. 111-113
    • Frosst, P.1    Blom, H.J.2    Milos, R.3    Goyette, P.4    Sheppard, C.A.5    Matthews, R.G.6
  • 24
    • 0031971515 scopus 로고    scopus 로고
    • A second common mutation in the methylenetetrahydrofolate reductase gene: An additional risk facror for neural-tube defects?
    • van der Put NM, Gabreels F, Srevens EM, Smeitink JA, Trijbels FJ, Eskes TK, et al. A second common mutation in the methylenetetrahydrofolate reductase gene: an additional risk facror for neural-tube defects? Am J Hum Genet 1998;62:1044-1051.
    • (1998) Am J Hum Genet , vol.62 , pp. 1044-1051
    • van der Put, N.M.1    Gabreels, F.2    Srevens, E.M.3    Smeitink, J.A.4    Trijbels, F.J.5    Eskes, T.K.6
  • 25
    • 0030811925 scopus 로고    scopus 로고
    • Genetic predisposition to hyperhomocysteinemia: Deficiency of methylenetetrahydrofolate reductase (MTHFR)
    • Rozen R. Genetic predisposition to hyperhomocysteinemia: deficiency of methylenetetrahydrofolate reductase (MTHFR). Thromb Haemost 1997;78:523-526.
    • (1997) Thromb Haemost , vol.78 , pp. 523-526
    • Rozen, R.1
  • 26
    • 0031687887 scopus 로고    scopus 로고
    • A second genetic polymorphism in methylenetetrahydrofolate reductase (MTHFR) associated with decreased enzyme activity
    • Weisberg I, Tran P, Christensen B, Sibani S, Rozen R. A second genetic polymorphism in methylenetetrahydrofolate reductase (MTHFR) associated with decreased enzyme activity. Mol Genet Metab 1998;64:169-172.
    • (1998) Mol Genet Metab , vol.64 , pp. 169-172
    • Weisberg, I.1    Tran, P.2    Christensen, B.3    Sibani, S.4    Rozen, R.5
  • 27
    • 0030979178 scopus 로고    scopus 로고
    • Folate deficiency causes uracil misincorporation into human DNA and chromosome breakage: Implications for cancer and neuronal damage
    • Blount BC, Mack MM, Wehr CM, MacGregor JT, Hiatt RA, Wang G, et al. Folate deficiency causes uracil misincorporation into human DNA and chromosome breakage: implications for cancer and neuronal damage. Proc Natl Acad Sci U S A 1997;94:3290-3295.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 3290-3295
    • Blount, B.C.1    Mack, M.M.2    Wehr, C.M.3    MacGregor, J.T.4    Hiatt, R.A.5    Wang, G.6
  • 28
    • 1442300286 scopus 로고    scopus 로고
    • Polymorphisms in genes involved in folate metabolism and colorectal neoplasia: A HuGE review
    • Sharp L, Little J. Polymorphisms in genes involved in folate metabolism and colorectal neoplasia: a HuGE review. Am J Epidemiol 2004;159:423-443.
    • (2004) Am J Epidemiol , vol.159 , pp. 423-443
    • Sharp, L.1    Little, J.2
  • 29
    • 13444253760 scopus 로고    scopus 로고
    • Effect of cytokine genotypes on the hepatitis B virus-hepatocellular carcinoma association
    • Nieters A, Yuan JM, Sun CL, Zhang ZQ, Stoehlmacher J, Govindarajan S, et al. Effect of cytokine genotypes on the hepatitis B virus-hepatocellular carcinoma association. Cancer 2005;103:740-748.
    • (2005) Cancer , vol.103 , pp. 740-748
    • Nieters, A.1    Yuan, J.M.2    Sun, C.L.3    Zhang, Z.Q.4    Stoehlmacher, J.5    Govindarajan, S.6
  • 30
    • 0027291689 scopus 로고
    • Allelic discrimination by nick-translation PCR with fluorogenic probes
    • Lee LG, Connell CR, Bloch W. Allelic discrimination by nick-translation PCR with fluorogenic probes. Nucl Acids Res 1993;21:3761-3766.
    • (1993) Nucl Acids Res , vol.21 , pp. 3761-3766
    • Lee, L.G.1    Connell, C.R.2    Bloch, W.3
  • 31
    • 0000154003 scopus 로고
    • Statistical methods in cancer research
    • Lyon: IARC Scientific Publication
    • Breslow NE, Day NE. Statistical methods in cancer research. Volume 1. The analysis of case-control studies. Lyon: IARC Scientific Publication, 1980:192-279.
    • (1980) The analysis of case-control studies , vol.1 , pp. 192-279
    • Breslow, N.E.1    Day, N.E.2
  • 32
    • 0030131165 scopus 로고    scopus 로고
    • Testing for linkage disequilibrium in genotypic data using the Expectation-Maximization algorithm
    • Slatkin M, Excoffier L. Testing for linkage disequilibrium in genotypic data using the Expectation-Maximization algorithm. Heredity 1996;76:377-383.
    • (1996) Heredity , vol.76 , pp. 377-383
    • Slatkin, M.1    Excoffier, L.2
  • 33
    • 0036208832 scopus 로고    scopus 로고
    • Patterns of linkage disequilibrium in the human genome
    • Ardlie KG, Kruglyak L, Seielstad M. Patterns of linkage disequilibrium in the human genome. Nat Rev Genet 2002;3:299-309.
    • (2002) Nat Rev Genet , vol.3 , pp. 299-309
    • Ardlie, K.G.1    Kruglyak, L.2    Seielstad, M.3
  • 35
    • 0033623867 scopus 로고    scopus 로고
    • The effect of 677C→T and 1298A→C mutations on plasma homocysteine and 5,10-methylenetetrahydrofolate reductase activity in healthy subjects
    • Chango A, Boisson F, Barbe F, Quilliot D, Droesch S, Pfister M, et al. The effect of 677C→T and 1298A→C mutations on plasma homocysteine and 5,10-methylenetetrahydrofolate reductase activity in healthy subjects. Br J Nutr 2000;83:593-596.
    • (2000) Br J Nutr , vol.83 , pp. 593-596
    • Chango, A.1    Boisson, F.2    Barbe, F.3    Quilliot, D.4    Droesch, S.5    Pfister, M.6
  • 36
    • 19944366586 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase C677T and A1298C polymorphisms and colorectal cancer: The Fukuoka Colorectal Cancer Study
    • Yin G, Kono S, Toyomura K, Hagiwara T, Nagano J, Mizoue T, et al. Methylenetetrahydrofolate reductase C677T and A1298C polymorphisms and colorectal cancer: the Fukuoka Colorectal Cancer Study. Cancer Sci 2004;95:908-913.
    • (2004) Cancer Sci , vol.95 , pp. 908-913
    • Yin, G.1    Kono, S.2    Toyomura, K.3    Hagiwara, T.4    Nagano, J.5    Mizoue, T.6
  • 37
    • 4344703254 scopus 로고    scopus 로고
    • The MTHFR 677C > T polymorphism is associated with an increased risk of hepatocellular carcinoma in patients with alcoholic cirrhosis
    • Saffroy R, Pham P, Chiappini F, Gross-Goupil M, Castera L, Azoulay D, et al. The MTHFR 677C > T polymorphism is associated with an increased risk of hepatocellular carcinoma in patients with alcoholic cirrhosis. Carcinogenesis 2004;25:1443-1448.
    • (2004) Carcinogenesis , vol.25 , pp. 1443-1448
    • Saffroy, R.1    Pham, P.2    Chiappini, F.3    Gross-Goupil, M.4    Castera, L.5    Azoulay, D.6
  • 38
    • 0030615085 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase polymorphism, dietary interactions, and risk of colorectal cancer
    • Ma J, Stampfer MJ, Giovannucci E, Artigas C, Hunter DJ, Fuchs C, et al. Methylenetetrahydrofolate reductase polymorphism, dietary interactions, and risk of colorectal cancer. Cancer Res 1997;57:1098-1102.
    • (1997) Cancer Res , vol.57 , pp. 1098-1102
    • Ma, J.1    Stampfer, M.J.2    Giovannucci, E.3    Artigas, C.4    Hunter, D.J.5    Fuchs, C.6
  • 39
    • 0034979766 scopus 로고    scopus 로고
    • Dietary folate intake, alcohol, and risk of breast cancer in a prospective study of postmenopausal women
    • Sellers TA, Kushi LH, Cerhan JR, Vierkant RA, Gapstur SM, Vachon CM, et al. Dietary folate intake, alcohol, and risk of breast cancer in a prospective study of postmenopausal women. Epidemiology 2001;12:420-428.
    • (2001) Epidemiology , vol.12 , pp. 420-428
    • Sellers, T.A.1    Kushi, L.H.2    Cerhan, J.R.3    Vierkant, R.A.4    Gapstur, S.M.5    Vachon, C.M.6
  • 40
    • 22844432759 scopus 로고    scopus 로고
    • Gene-environment interactions between alcohol drinking and the MTHFR C677T polymorphism impact on esophageal cancer risk: Results of a case-control study in Japan
    • Yang CX, Matsuo K, Ito H, Shinoda M, Hatooka S, Hirose K, et al. Gene-environment interactions between alcohol drinking and the MTHFR C677T polymorphism impact on esophageal cancer risk: results of a case-control study in Japan. Carcinogenesis 2005;26:1285-1290.
    • (2005) Carcinogenesis , vol.26 , pp. 1285-1290
    • Yang, C.X.1    Matsuo, K.2    Ito, H.3    Shinoda, M.4    Hatooka, S.5    Hirose, K.6
  • 42
    • 23444436011 scopus 로고    scopus 로고
    • Alcohol intake and methylenetetrahydrofolate reductase polymorphism modify the relation of folate intake to plasma homocysteine
    • Chiuve SE, Giovannucci EL, Hankinson SE, Hunter DJ, Stampfer MJ, Willett WC, et al. Alcohol intake and methylenetetrahydrofolate reductase polymorphism modify the relation of folate intake to plasma homocysteine. Am J Clin Nutr 2005;82:155-162.
    • (2005) Am J Clin Nutr , vol.82 , pp. 155-162
    • Chiuve, S.E.1    Giovannucci, E.L.2    Hankinson, S.E.3    Hunter, D.J.4    Stampfer, M.J.5    Willett, W.C.6
  • 43
    • 27944455699 scopus 로고    scopus 로고
    • One-carbon metabolism related gene polymorphisms interact with alcohol drinking to influence the risk of colorectal cancer in Japan
    • Matsuo K, Ito H, Wakai K, Hirose K, Saito T, Suzuki T, et al. One-carbon metabolism related gene polymorphisms interact with alcohol drinking to influence the risk of colorectal cancer in Japan. Carcinogenesis 2005;26:2164-2171.
    • (2005) Carcinogenesis , vol.26 , pp. 2164-2171
    • Matsuo, K.1    Ito, H.2    Wakai, K.3    Hirose, K.4    Saito, T.5    Suzuki, T.6
  • 45
    • 22944451793 scopus 로고    scopus 로고
    • Polymorphisms of methionine synthase and methionine synthase reductase and risk of lung cancer: A case-control analysis
    • Shi Q, Zhang Z, Li G, Pillow PC, Hernandez LM, Spitz MR, et al. Polymorphisms of methionine synthase and methionine synthase reductase and risk of lung cancer: a case-control analysis. Pharmacogenetics & Genomics 2005;15:547-555.
    • (2005) Pharmacogenetics & Genomics , vol.15 , pp. 547-555
    • Shi, Q.1    Zhang, Z.2    Li, G.3    Pillow, P.C.4    Hernandez, L.M.5    Spitz, M.R.6
  • 46
    • 27144478904 scopus 로고    scopus 로고
    • Polymorphisms of thymidylate synthase in the 5′- and 3′-untranslated regions associated with risk of gastric cancer in South China: A case-control analysis
    • Zhang Z, Xu Y, Zhou J, Wang X, Wang L, Hu X, et al. Polymorphisms of thymidylate synthase in the 5′- and 3′-untranslated regions associated with risk of gastric cancer in South China: a case-control analysis. Carcinogenesis 2005;26:1764-1769.
    • (2005) Carcinogenesis , vol.26 , pp. 1764-1769
    • Zhang, Z.1    Xu, Y.2    Zhou, J.3    Wang, X.4    Wang, L.5    Hu, X.6
  • 47
    • 0037096858 scopus 로고    scopus 로고
    • Thymidylate synthase promoter polymorphism, interaction with folate intake, and risk of colorectal adenomas
    • Ulrich CM, Bigler J, Bostick R, Fosdick L, Potter JD. Thymidylate synthase promoter polymorphism, interaction with folate intake, and risk of colorectal adenomas. Cancer Res 2002;62:3361-3364.
    • (2002) Cancer Res , vol.62 , pp. 3361-3364
    • Ulrich, C.M.1    Bigler, J.2    Bostick, R.3    Fosdick, L.4    Potter, J.D.5
  • 49
    • 33847114380 scopus 로고    scopus 로고
    • Polymorphisms in thymidylate synthase gene and susceptibility to breast cancer in a Chinese population: A case-control analysis
    • Zhai X, Gao J, Hu Z, Tang J, Qin J, Wang S, et al. Polymorphisms in thymidylate synthase gene and susceptibility to breast cancer in a Chinese population: a case-control analysis. BMC Cancer 2006;6:138.
    • (2006) BMC Cancer , vol.6 , pp. 138
    • Zhai, X.1    Gao, J.2    Hu, Z.3    Tang, J.4    Qin, J.5    Wang, S.6
  • 50
    • 25144517063 scopus 로고    scopus 로고
    • Relationships between promoter polymorphisms in the thymidylate synthase gene and mRNA levels in colorectal cancers
    • Morganti M, Ciantelli M, Giglioni B, Putignano AL, Nobili S, Papi L, et al. Relationships between promoter polymorphisms in the thymidylate synthase gene and mRNA levels in colorectal cancers. Eur J Cancer 2005;41:2176-2183.
    • (2005) Eur J Cancer , vol.41 , pp. 2176-2183
    • Morganti, M.1    Ciantelli, M.2    Giglioni, B.3    Putignano, A.L.4    Nobili, S.5    Papi, L.6
  • 51
    • 17844385292 scopus 로고    scopus 로고
    • Hyperhomocysteinemia and the MTHFR C677T polymorphism promote steatosis and fibrosis in chronic hepatitis C patients
    • Adinolfi LE, Ingrosso D, Cesaro G, Cimmino A, D'Anto M, Capasso R, et al. Hyperhomocysteinemia and the MTHFR C677T polymorphism promote steatosis and fibrosis in chronic hepatitis C patients. HEPATOLOGY 2005;41:995-1003.
    • (2005) HEPATOLOGY , vol.41 , pp. 995-1003
    • Adinolfi, L.E.1    Ingrosso, D.2    Cesaro, G.3    Cimmino, A.4    D'Anto, M.5    Capasso, R.6
  • 54
    • 0026064347 scopus 로고
    • Repair of uracil residues closely spaced on the opposite strands of plasmid DNA results in double-strand break and deletion formation
    • Dianov GL, Timchenko TV, Sinitsina OI, Kuzminov AV, Medvedev OA, Salganik RI. Repair of uracil residues closely spaced on the opposite strands of plasmid DNA results in double-strand break and deletion formation. Mol Gen Genet 1991;225:448-452.
    • (1991) Mol Gen Genet , vol.225 , pp. 448-452
    • Dianov, G.L.1    Timchenko, T.V.2    Sinitsina, O.I.3    Kuzminov, A.V.4    Medvedev, O.A.5    Salganik, R.I.6
  • 55
    • 0242610825 scopus 로고    scopus 로고
    • Role of folate in colon cancer development and progression
    • Kim YI. Role of folate in colon cancer development and progression. J Nutr 2003;133:3731S-3739S.
    • (2003) J Nutr , vol.133
    • Kim, Y.I.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.