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Volumn 9, Issue 7, 2014, Pages

Integrated analysis of mutation data from various sources identifies key genes and signaling pathways in hepatocellular carcinoma

Author keywords

[No Author keywords available]

Indexed keywords

ADCY GENE; ALB GENE; APOPTOSIS; ARID1A GENE; ARID2 GENE; ARTICLE; AXIN1 GENE; CARCINOGENESIS; CELL PROLIFERATION; CIRCADIAN RELATED PATHWAY; COL11A1 GENE; CONTROLLED STUDY; CTNNB1 GENE; GENE FUNCTION; GENE IDENTIFICATION; GENE MUTATION; GENETIC ASSOCIATION; GNAL GENE; GPR98 GENE; HUMAN; LIVER CELL CARCINOMA; LRP1B GENE; METABOLIC RELATED PATHWAY; MLL3 GENE; NEURAL SIGNALING RELATED PATHWAY; ONCOGENE; PCLO GENE; PROLIFERATION AND APOPTOSIS RELATED PATHWAY; RPS6KA3 GENE; SIGNAL TRANSDUCTION; TP53 GENE; TUMOR MICROENVIRONMENT; TUMOR MICROENVIRONMENT RELATED PATHWAY; USH2A GENE; GENETICS; INFORMATION PROCESSING; LIVER TUMOR; MUTATION; NUCLEIC ACID DATABASE; NUCLEOTIDE SEQUENCE; TUMOR GENE;

EID: 84903770490     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0100854     Document Type: Article
Times cited : (36)

References (57)
  • 1
    • 84861625981 scopus 로고    scopus 로고
    • Integrated analysis of somatic mutations and focal copy-number changes identifies key genes and pathways in hepatocellular carcinoma
    • Guichard C, Amaddeo G, Imbeaud S, Ladeiro Y, Pelletier L, et al. (2012) Integrated analysis of somatic mutations and focal copy-number changes identifies key genes and pathways in hepatocellular carcinoma. Nat Genet 44: 694-698.
    • (2012) Nat Genet , vol.44 , pp. 694-698
    • Guichard, C.1    Amaddeo, G.2    Imbeaud, S.3    Ladeiro, Y.4    Pelletier, L.5
  • 3
    • 84890565243 scopus 로고    scopus 로고
    • Genetics of hepatocellular carcinoma: The next generation
    • Nault JC, Zucman-Rossi J (2014) Genetics of hepatocellular carcinoma: the next generation. J Hepatol 60: 224-226.
    • (2014) J Hepatol , vol.60 , pp. 224-226
    • Nault, J.C.1    Zucman-Rossi, J.2
  • 4
    • 84862976633 scopus 로고    scopus 로고
    • Whole-genome sequencing of liver cancers identifies etiological influences on mutation patterns and recurrent mutations in chromatin regulators
    • Fujimoto A, Totoki Y, Abe T, Boroevich KA, Hosoda F, et al. (2012) Whole-genome sequencing of liver cancers identifies etiological influences on mutation patterns and recurrent mutations in chromatin regulators. Nat Genet 44: 760-764.
    • (2012) Nat Genet , vol.44 , pp. 760-764
    • Fujimoto, A.1    Totoki, Y.2    Abe, T.3    Boroevich, K.A.4    Hosoda, F.5
  • 5
    • 84866868120 scopus 로고    scopus 로고
    • Exome sequencing of hepatitis B virus-associated hepatocellular carcinoma
    • Huang J, Deng Q, Wang Q, Li KY, Dai JH, et al. (2012) Exome sequencing of hepatitis B virus-associated hepatocellular carcinoma. Nat Genet 44: 1117-1121.
    • (2012) Nat Genet , vol.44 , pp. 1117-1121
    • Huang, J.1    Deng, Q.2    Wang, Q.3    Li, K.Y.4    Dai, J.H.5
  • 6
    • 80052271807 scopus 로고    scopus 로고
    • Inactivating mutations of the chromatin remodeling gene ARID2 in hepatocellular carcinoma
    • Li M, Zhao H, Zhang X, Wood LD, Anders RA, et al. (2012) Inactivating mutations of the chromatin remodeling gene ARID2 in hepatocellular carcinoma. Nat Genet 43: 828-829.
    • (2012) Nat Genet , vol.43 , pp. 828-829
    • Li, M.1    Zhao, H.2    Zhang, X.3    Wood, L.D.4    Anders, R.A.5
  • 7
    • 84862999344 scopus 로고    scopus 로고
    • Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma
    • Sung WK, Zheng H, Li S, Chen R, Liu X, et al. (2012) Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet 44: 765-769.
    • (2012) Nat Genet , vol.44 , pp. 765-769
    • Sung, W.K.1    Zheng, H.2    Li, S.3    Chen, R.4    Liu, X.5
  • 9
    • 84856535081 scopus 로고    scopus 로고
    • Mutual exclusivity analysis identifies oncogenic network modules
    • Ciriello G, Cerami E, Sander C, Schultz N (2012) Mutual exclusivity analysis identifies oncogenic network modules. Genome Res 22: 398-406.
    • (2012) Genome Res , vol.22 , pp. 398-406
    • Ciriello, G.1    Cerami, E.2    Sander, C.3    Schultz, N.4
  • 11
    • 84883718528 scopus 로고    scopus 로고
    • Whole-genome sequencing identifies recurrent mutations in hepatocellular carcinoma
    • Kan Z, Zheng H, Liu X, Li S, Barber TD, et al. (2013) Whole-genome sequencing identifies recurrent mutations in hepatocellular carcinoma. Genome Res 23: 1422-1433.
    • (2013) Genome Res , vol.23 , pp. 1422-1433
    • Kan, Z.1    Zheng, H.2    Liu, X.3    Li, S.4    Barber, T.D.5
  • 13
    • 54549108740 scopus 로고    scopus 로고
    • Comprehensive genomic characterization defines human glioblastoma genes and core pathways
    • TCGA-Consortium
    • TCGA-Consortium (2008) Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature 455: 1061-1068.
    • (2008) Nature , vol.455 , pp. 1061-1068
  • 14
    • 0004216016 scopus 로고    scopus 로고
    • Cambridge, UK; New York: Cambridge University Press
    • Gasper G, Rahman M (2004) Basic hypergeometric series. Cambridge, UK; New York: Cambridge University Press. xxvi, 428 p.
    • (2004) Basic Hypergeometric Series
    • Gasper, G.1    Rahman, M.2
  • 15
    • 77956627711 scopus 로고    scopus 로고
    • The role of signaling pathways in the development and treatment of hepatocellular carcinoma
    • Whittaker S, Marais R, Zhu AX (2010) The role of signaling pathways in the development and treatment of hepatocellular carcinoma. Oncogene 29: 4989-5005.
    • (2010) Oncogene , vol.29 , pp. 4989-5005
    • Whittaker, S.1    Marais, R.2    Zhu, A.X.3
  • 16
    • 80053183510 scopus 로고    scopus 로고
    • Advances in liver cancer antibody therapies: A focus on glypican-3 and mesothelin
    • Ho M (2011) Advances in liver cancer antibody therapies: a focus on glypican-3 and mesothelin. BioDrugs 25: 275-284.
    • (2011) BioDrugs , vol.25 , pp. 275-284
    • Ho, M.1
  • 17
    • 4544250024 scopus 로고    scopus 로고
    • Gene-promoter hypermethylation as a biomarker in lung cancer
    • Belinsky SA (2004) Gene-promoter hypermethylation as a biomarker in lung cancer. Nat Rev Cancer 4: 707-717.
    • (2004) Nat Rev Cancer , vol.4 , pp. 707-717
    • Belinsky, S.A.1
  • 18
    • 84887184397 scopus 로고    scopus 로고
    • Genomics and epigenomics of clear cell renal cell carcinoma: Recent developments and potential applications
    • Rydzanicz M, Wrzesinski T, Bluyssen HA, Wesoly J (2013) Genomics and epigenomics of clear cell renal cell carcinoma: Recent developments and potential applications. Cancer Lett 341: 111-126.
    • (2013) Cancer Lett , vol.341 , pp. 111-126
    • Rydzanicz, M.1    Wrzesinski, T.2    Bluyssen, H.A.3    Wesoly, J.4
  • 20
    • 84869854258 scopus 로고    scopus 로고
    • Function and cancer genomics of FAT family genes
    • review
    • Katoh M (2012) Function and cancer genomics of FAT family genes (review). Int J Oncol 41: 1913-1918.
    • (2012) Int J Oncol , vol.41 , pp. 1913-1918
    • Katoh, M.1
  • 21
    • 84881025772 scopus 로고    scopus 로고
    • A novel APOB mutation identified by exome sequencing cosegregates with steatosis, liver cancer, and hypocholesterolemia
    • Cefalu AB, Pirruccello JP, Noto D, Gabriel S, Valenti V, et al. (2013) A novel APOB mutation identified by exome sequencing cosegregates with steatosis, liver cancer, and hypocholesterolemia. Arterioscler Thromb Vasc Biol 33: 2021-2025.
    • (2013) Arterioscler Thromb Vasc Biol , vol.33 , pp. 2021-2025
    • Cefalu, A.B.1    Pirruccello, J.P.2    Noto, D.3    Gabriel, S.4    Valenti, V.5
  • 22
    • 79960759956 scopus 로고    scopus 로고
    • Calcium in tumour metastasis: New roles for known actors
    • Prevarskaya N, Skryma R, Shuba Y (2011) Calcium in tumour metastasis: new roles for known actors. Nat Rev Cancer 11: 609-618.
    • (2011) Nat Rev Cancer , vol.11 , pp. 609-618
    • Prevarskaya, N.1    Skryma, R.2    Shuba, Y.3
  • 23
    • 79952038728 scopus 로고    scopus 로고
    • The tumor microenvironment in hepatocellular carcinoma: Current status and therapeutic targets
    • Yang JD, Nakamura I, Roberts LR (2011) The tumor microenvironment in hepatocellular carcinoma: current status and therapeutic targets. Semin Cancer Biol 21: 35-43.
    • (2011) Semin Cancer Biol , vol.21 , pp. 35-43
    • Yang, J.D.1    Nakamura, I.2    Roberts, L.R.3
  • 25
    • 79953721970 scopus 로고    scopus 로고
    • Nerve growth factor in cancer cell death and survival
    • Molloy NH, Read DE, Gorman AM (2011) Nerve growth factor in cancer cell death and survival. Cancers (Basel) 3: 510-530.
    • (2011) Cancers (Basel) , vol.3 , pp. 510-530
    • Molloy, N.H.1    Read, D.E.2    Gorman, A.M.3
  • 26
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • Hanahan D, Weinberg RA (2011) Hallmarks of cancer: the next generation. Cell 144: 646-674.
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 27
    • 70450239457 scopus 로고    scopus 로고
    • Metabolism and cancer: The circadian clock connection
    • Sahar S, Sassone-Corsi P (2009) Metabolism and cancer: the circadian clock connection. Nat Rev Cancer 9: 886-896.
    • (2009) Nat Rev Cancer , vol.9 , pp. 886-896
    • Sahar, S.1    Sassone-Corsi, P.2
  • 28
    • 80053029993 scopus 로고    scopus 로고
    • Augmenting the antitumor effect of TRAIL by SOCS3 with double-regulated replicating oncolytic adenovirus in hepatocellular carcinoma
    • Wei RC, Cao X, Gui JH, Zhou XM, Zhong D, et al. (2011) Augmenting the antitumor effect of TRAIL by SOCS3 with double-regulated replicating oncolytic adenovirus in hepatocellular carcinoma. Hum Gene Ther 22: 1109-1119.
    • (2011) Hum Gene Ther , vol.22 , pp. 1109-1119
    • Wei, R.C.1    Cao, X.2    Gui, J.H.3    Zhou, X.M.4    Zhong, D.5
  • 29
    • 84890761844 scopus 로고    scopus 로고
    • Leptin receptor somatic mutations are frequent in HCV-infected cirrhotic liver and associated with hepatocellular carcinoma
    • Ikeda A, Shimizu T, Matsumoto Y, Fujii Y, Eso Y, et al. (2014) Leptin receptor somatic mutations are frequent in HCV-infected cirrhotic liver and associated with hepatocellular carcinoma. Gastroenterology 146: 222-232 e235.
    • (2014) Gastroenterology , vol.146
    • Ikeda, A.1    Shimizu, T.2    Matsumoto, Y.3    Fujii, Y.4    Eso, Y.5
  • 30
    • 79751492851 scopus 로고    scopus 로고
    • NF-kappaB in the liver-linking injury, fibrosis and hepatocellular carcinoma
    • Luedde T, Schwabe RF (2011) NF-kappaB in the liver-linking injury, fibrosis and hepatocellular carcinoma. Nat Rev Gastroenterol Hepatol 8: 108-118.
    • (2011) Nat Rev Gastroenterol Hepatol , vol.8 , pp. 108-118
    • Luedde, T.1    Schwabe, R.F.2
  • 31
    • 33846212284 scopus 로고    scopus 로고
    • Sorafenib blocks the RAF/MEK/ERK pathway, inhibits tumor angiogenesis, and induces tumor cell apoptosis in hepatocellular carcinoma model PLC/PRF/5
    • DOI 10.1158/0008-5472.CAN-06-1377
    • Liu L, Cao Y, Chen C, Zhang X, McNabola A, et al. (2006) Sorafenib blocks the RAF/MEK/ERK pathway, inhibits tumor angiogenesis, and induces tumor cell apoptosis in hepatocellular carcinoma model PLC/PRF/5. Cancer Res 66: 11851-11858. (Pubitemid 46094197)
    • (2006) Cancer Research , vol.66 , Issue.24 , pp. 11851-11858
    • Liu, L.1    Cao, Y.2    Chen, C.3    Zhang, X.4    McNabola, A.5    Wilkie, D.6    Wilhelm, S.7    Lynch, M.8    Carter, C.9
  • 32
    • 34548321204 scopus 로고    scopus 로고
    • Nuclear factor-kappaB and the hepatic inflammation-fibrosis-cancer axis
    • DOI 10.1002/hep.21802
    • Elsharkawy AM, Mann DA (2007) Nuclear factor-kappaB and the hepatic inflammation-fibrosis-cancer axis. Hepatology 46: 590-597. (Pubitemid 47344795)
    • (2007) Hepatology , vol.46 , Issue.2 , pp. 590-597
    • Elsharkawy, A.M.1    Mann, D.A.2
  • 33
    • 38849184816 scopus 로고    scopus 로고
    • PPARalpha activation is essential for HCV core protein-induced hepatic steatosis and hepatocellular carcinoma in mice
    • DOI 10.1172/JCI33594
    • Tanaka N, Moriya K, Kiyosawa K, Koike K, Gonzalez FJ, et al. (2008) PPARalpha activation is essential for HCV core protein-induced hepatic steatosis and hepatocellular carcinoma in mice. J Clin Invest 118: 683-694. (Pubitemid 351206557)
    • (2008) Journal of Clinical Investigation , vol.118 , Issue.2 , pp. 683-694
    • Tanaka, N.1    Moriya, K.2    Kiyosawa, K.3    Koike, K.4    Gonzalez, F.J.5    Aoyama, T.6
  • 34
    • 84864198388 scopus 로고    scopus 로고
    • A liver full of JNK: Signaling in regulation of cell function and disease pathogenesis, and clinical approaches
    • Seki E, Brenner DA, Karin M (2012) A liver full of JNK: signaling in regulation of cell function and disease pathogenesis, and clinical approaches. Gastroenterology 143: 307-320.
    • (2012) Gastroenterology , vol.143 , pp. 307-320
    • Seki, E.1    Brenner, D.A.2    Karin, M.3
  • 35
    • 82455162659 scopus 로고    scopus 로고
    • HAb18G/CD147 promotes cell motility by regulating annexin II-activated RhoA and Rac1 signaling pathways in hepatocellular carcinoma cells
    • Zhao P, Zhang W, Wang SJ, Yu XL, Tang J, et al. (2011) HAb18G/CD147 promotes cell motility by regulating annexin II-activated RhoA and Rac1 signaling pathways in hepatocellular carcinoma cells. Hepatology 54: 2012-2024.
    • (2011) Hepatology , vol.54 , pp. 2012-2024
    • Zhao, P.1    Zhang, W.2    Wang, S.J.3    Yu, X.L.4    Tang, J.5
  • 37
    • 83555161680 scopus 로고    scopus 로고
    • GNAS-activating mutations define a rare subgroup of inflammatory liver tumors characterized by STAT3 activation
    • Nault JC, Fabre M, Couchy G, Pilati C, Jeannot E, et al. (2012) GNAS-activating mutations define a rare subgroup of inflammatory liver tumors characterized by STAT3 activation. J Hepatol 56: 184-191.
    • (2012) J Hepatol , vol.56 , pp. 184-191
    • Nault, J.C.1    Fabre, M.2    Couchy, G.3    Pilati, C.4    Jeannot, E.5
  • 38
    • 0142213943 scopus 로고    scopus 로고
    • PTK2 and EIF3S3 genes may be amplification targets at 8q23-q24 and are associated with large hepatocellular carcinomas
    • Okamoto H, Yasui K, Zhao C, Arii S, Inazawa J (2003) PTK2 and EIF3S3 genes may be amplification targets at 8q23-q24 and are associated with large hepatocellular carcinomas. Hepatology 38: 1242-1249.
    • (2003) Hepatology , vol.38 , pp. 1242-1249
    • Okamoto, H.1    Yasui, K.2    Zhao, C.3    Arii, S.4    Inazawa, J.5
  • 39
    • 3042579870 scopus 로고    scopus 로고
    • Evaluation of nuclear factor-kappaB, urokinase-type plasminogen activator, and HBx and their clinicopathological significance in hepatocellular carcinoma
    • Chan CF, Yau TO, Jin DY, Wong CM, Fan ST, et al. (2004) Evaluation of nuclear factor-kappaB, urokinase-type plasminogen activator, and HBx and their clinicopathological significance in hepatocellular carcinoma. Clin Cancer Res 10: 4140-4149.
    • (2004) Clin Cancer Res , vol.10 , pp. 4140-4149
    • Chan, C.F.1    Yau, T.O.2    Jin, D.Y.3    Wong, C.M.4    Fan, S.T.5
  • 40
    • 50949109286 scopus 로고    scopus 로고
    • Correlations of the expression of vascular endothelial growth factor B and its isoforms in hepatocellular carcinoma with clinico-pathological parameters
    • Kanda M, Nomoto S, Nishikawa Y, Sugimoto H, Kanazumi N, et al. (2008) Correlations of the expression of vascular endothelial growth factor B and its isoforms in hepatocellular carcinoma with clinico-pathological parameters. J Surg Oncol 98: 190-196.
    • (2008) J Surg Oncol , vol.98 , pp. 190-196
    • Kanda, M.1    Nomoto, S.2    Nishikawa, Y.3    Sugimoto, H.4    Kanazumi, N.5
  • 41
    • 84857050018 scopus 로고    scopus 로고
    • Chemokine-driven lymphocyte infiltration: An early intratumoural event determining long-term survival in resectable hepatocellular carcinoma
    • Chew V, Chen J, Lee D, Loh E, Lee J, et al. (2012) Chemokine-driven lymphocyte infiltration: an early intratumoural event determining long-term survival in resectable hepatocellular carcinoma. Gut 61: 427-438.
    • (2012) Gut , vol.61 , pp. 427-438
    • Chew, V.1    Chen, J.2    Lee, D.3    Loh, E.4    Lee, J.5
  • 43
    • 77949532152 scopus 로고    scopus 로고
    • Extracting consistent knowledge from highly inconsistent cancer gene data sources
    • Gong X, Wu R, Zhang Y, Zhao W, Cheng L, et al. (2010) Extracting consistent knowledge from highly inconsistent cancer gene data sources. BMC Bioinformatics 11: 76.
    • (2010) BMC Bioinformatics , vol.11 , pp. 76
    • Gong, X.1    Wu, R.2    Zhang, Y.3    Zhao, W.4    Cheng, L.5
  • 44
    • 52449095361 scopus 로고    scopus 로고
    • The RSK family of kinases: Emerging roles in cellular signalling
    • Anjum R, Blenis J (2008) The RSK family of kinases: emerging roles in cellular signalling. Nat Rev Mol Cell Biol 9: 747-758.
    • (2008) Nat Rev Mol Cell Biol , vol.9 , pp. 747-758
    • Anjum, R.1    Blenis, J.2
  • 45
    • 0033982936 scopus 로고    scopus 로고
    • KEGG: Kyoto Encyclopedia of Genes and Genomes
    • Kanehisa M, Goto S (2000) KEGG: kyoto encyclopedia of genes and genomes. Nucleic Acids Res 28: 27-30. (Pubitemid 30047706)
    • (2000) Nucleic Acids Research , vol.28 , Issue.1 , pp. 27-30
    • Kanehisa, M.1    Goto, S.2
  • 47
    • 84863368720 scopus 로고    scopus 로고
    • Downregulation of MAGI1 associates with poor prognosis of hepatocellular carcinoma
    • Zhang G, Liu T, Wang Z (2012) Downregulation of MAGI1 associates with poor prognosis of hepatocellular carcinoma. J Invest Surg 25: 93-99.
    • (2012) J Invest Surg , vol.25 , pp. 93-99
    • Zhang, G.1    Liu, T.2    Wang, Z.3
  • 48
    • 79951576642 scopus 로고    scopus 로고
    • Overexpression of Cullin1 is associated with poor prognosis of patients with gastric cancer
    • Bai J, Zhou Y, Chen G, Zeng J, Ding J, et al. (2011) Overexpression of Cullin1 is associated with poor prognosis of patients with gastric cancer. Hum Pathol 42: 375-383.
    • (2011) Hum Pathol , vol.42 , pp. 375-383
    • Bai, J.1    Zhou, Y.2    Chen, G.3    Zeng, J.4    Ding, J.5
  • 49
    • 77349092851 scopus 로고    scopus 로고
    • Molecular classification and novel targets in hepatocellular carcinoma: Recent advancements
    • Hoshida Y, Toffanin S, Lachenmayer A, Villanueva A, Minguez B, et al. (2010) Molecular classification and novel targets in hepatocellular carcinoma: recent advancements. Semin Liver Dis 30: 35-51.
    • (2010) Semin Liver Dis , vol.30 , pp. 35-51
    • Hoshida, Y.1    Toffanin, S.2    Lachenmayer, A.3    Villanueva, A.4    Minguez, B.5
  • 50
    • 84881294106 scopus 로고    scopus 로고
    • Vascular endothelial cells facilitated HCC invasion and metastasis through the Akt and NF-kappaB pathways induced by paracrine cytokines
    • Wang YH, Dong YY, Wang WM, Xie XY, Wang ZM, et al. (2013) Vascular endothelial cells facilitated HCC invasion and metastasis through the Akt and NF-kappaB pathways induced by paracrine cytokines. J Exp Clin Cancer Res 32: 51.
    • (2013) J Exp Clin Cancer Res , vol.32 , pp. 51
    • Wang, Y.H.1    Dong, Y.Y.2    Wang, W.M.3    Xie, X.Y.4    Wang, Z.M.5
  • 51
    • 84865332828 scopus 로고    scopus 로고
    • Downregulation of the Notch signaling pathway inhibits hepatocellular carcinoma cell invasion by inactivation of matrix metalloproteinase-2 and -9 and vascular endothelial growth factor
    • Zhou L, Wang DS, Li QJ, Sun W, Zhang Y, et al. (2012) Downregulation of the Notch signaling pathway inhibits hepatocellular carcinoma cell invasion by inactivation of matrix metalloproteinase-2 and -9 and vascular endothelial growth factor. Oncol Rep 28: 874-882.
    • (2012) Oncol Rep , vol.28 , pp. 874-882
    • Zhou, L.1    Wang, D.S.2    Li, Q.J.3    Sun, W.4    Zhang, Y.5
  • 52
    • 84878370719 scopus 로고    scopus 로고
    • The role of axon guidance factor semaphorin 6B in the invasion and metastasis of gastric cancer
    • Ge C, Li Q, Wang L, Xu X (2013) The role of axon guidance factor semaphorin 6B in the invasion and metastasis of gastric cancer. J Int Med Res 41: 284-292.
    • (2013) J Int Med Res , vol.41 , pp. 284-292
    • Ge, C.1    Li, Q.2    Wang, L.3    Xu, X.4
  • 53
    • 0344464738 scopus 로고    scopus 로고
    • TSGDB: A database system for tumor suppressor genes
    • DOI 10.1093/bioinformatics/btg300
    • Yang Y, Fu LM (2003) TSGDB: a database system for tumor suppressor genes. Bioinformatics 19: 2311-2312. (Pubitemid 37483988)
    • (2003) Bioinformatics , vol.19 , Issue.17 , pp. 2311-2312
    • Yang, Y.1    Fu, L.M.2
  • 54
    • 0036713510 scopus 로고    scopus 로고
    • Human non-synonymous SNPs: Server and survey
    • Ramensky V, Bork P, Sunyaev S (2002) Human non-synonymous SNPs: server and survey. Nucleic Acids Res 30: 3894-3900. (Pubitemid 35012462)
    • (2002) Nucleic Acids Research , vol.30 , Issue.17 , pp. 3894-3900
    • Ramensky, V.1    Bork, P.2    Sunyaev, S.3
  • 55
    • 77956534324 scopus 로고    scopus 로고
    • ANNOVAR: Functional annotation of genetic variants from high-throughput sequencing data
    • Wang K, Li M, Hakonarson H (2010) ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data. Nucleic Acids Res 38: e164.
    • (2010) Nucleic Acids Res , vol.38
    • Wang, K.1    Li, M.2    Hakonarson, H.3
  • 56
    • 78651237647 scopus 로고    scopus 로고
    • Identifying a high fraction of the human genome to be under selective constraint using GERP++
    • Davydov EV, Goode DL, Sirota M, Cooper GM, Sidow A, et al. (2010) Identifying a high fraction of the human genome to be under selective constraint using GERP++. PLoS Comput Biol 6: e1001025.
    • (2010) PLoS Comput Biol , vol.6
    • Davydov, E.V.1    Goode, D.L.2    Sirota, M.3    Cooper, G.M.4    Sidow, A.5
  • 57
    • 0001677717 scopus 로고
    • Controlling the false discovery rate: A practical and powerful approach to multiple testing
    • Benjamini Y, Hochberg Y (1995) Controlling the false discovery rate: a practical and powerful approach to multiple testing. J R Stat Soc Series B (Methodol), 57: 289-300.
    • (1995) J R Stat Soc Series B (Methodol) , vol.57 , pp. 289-300
    • Benjamini, Y.1    Hochberg, Y.2


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