메뉴 건너뛰기




Volumn 7, Issue 286, 2015, Pages

Identification of a plant isoflavonoid that causes biliary atresia

Author keywords

[No Author keywords available]

Indexed keywords

BILIATRESONE; ISOFLAVONOID; UNCLASSIFIED DRUG; FLAVONOID; PLANT EXTRACT;

EID: 84928975439     PISSN: 19466234     EISSN: 19466242     Source Type: Journal    
DOI: 10.1126/scitranslmed.aaa1652     Document Type: Article
Times cited : (129)

References (72)
  • 1
    • 0141682658 scopus 로고    scopus 로고
    • Biliary atresia. Gastroenterol
    • B. A. Haber, P. Russo, Biliary atresia. Gastroenterol. Clin. North Am. 32, 891-911 (2003).
    • (2003) Clin. North Am , vol.32 , pp. 891-911
    • Haber, B.A.1    Russo, P.2
  • 7
    • 26244442249 scopus 로고    scopus 로고
    • Potential etiologies of biliary atresia
    • J. A. Bezerra, Potential etiologies of biliary atresia. Pediatr. Transplant. 9, 646-651 (2005).
    • (2005) Pediatr. Transplant , vol.9 , pp. 646-651
    • Bezerra, J.A.1
  • 11
    • 84873364829 scopus 로고    scopus 로고
    • Clues to the etiology of bile duct injury in biliary atresia
    • C. L. Mack, A. G. Feldman, R. J. Sokol, Clues to the etiology of bile duct injury in biliary atresia. Semin. Liver Dis. 32, 307-316 (2012).
    • (2012) Semin. Liver Dis , vol.32 , pp. 307-316
    • Mack, C.L.1    Feldman, A.G.2    Sokol, R.J.3
  • 13
    • 0025097119 scopus 로고
    • Congenital biliary atresia and jaundice in lambs and calves
    • P. Harper, J. W. Plant, D. B. Unger, Congenital biliary atresia and jaundice in lambs and calves. Aust. Vet. J. 67, 18-22 (1990).
    • (1990) Aust. Vet. J , vol.67 , pp. 18-22
    • Harper, P.1    Plant, J.W.2    Unger, D.B.3
  • 14
    • 84928948322 scopus 로고    scopus 로고
    • Congenital biliary atresia and jaundice in lambs
    • NSW Department of Primary Industries, Sydney, New South Wales, Australia
    • S. Robson, Congenital biliary atresia and jaundice in lambs, in New South Wales Animal Health Surveillance (NSW Department of Primary Industries, Sydney, New South Wales, Australia, 2007), vol. 2, pp. 2-4.
    • (2007) New South Wales Animal Health Surveillance , vol.2 , pp. 2-4
    • Robson, S.1
  • 16
    • 0028518736 scopus 로고
    • Phenolics induced in Beta vulgaris by Rhizoctonia solani infection
    • C. A. Elliger, J. M. Halloin, Phenolics induced in Beta vulgaris by Rhizoctonia solani infection. Phytochemistry 37, 691-693 (1994).
    • (1994) Phytochemistry , vol.37 , pp. 691-693
    • Elliger, C.A.1    Halloin, J.M.2
  • 17
    • 0013473573 scopus 로고
    • Two phytoalexins from sugarbeet (Beta vulgaris) leaves
    • J. Geigert, F. R. Stermitz, G. Johnson, D. D. Maag, Two phytoalexins from sugarbeet (Beta vulgaris) leaves. Tetrahedron 29, 2703-2706 (1973).
    • (1973) Tetrahedron , vol.29 , pp. 2703-2706
    • Geigert, J.1    Stermitz, F.R.2    Johnson, G.3    Maag, D.D.4
  • 18
    • 10344236467 scopus 로고    scopus 로고
    • Inhibition of Jagged-mediated Notch signaling disrupts zebrafish biliary development and generates multi-organ defects compatible with an Alagille syndrome phenocopy
    • K. Lorent, S.-Y. Yeo, T. Oda, S. Chandrasekharappa, A. Chitnis, R. P. Matthews, M. Pack, Inhibition of Jagged-mediated Notch signaling disrupts zebrafish biliary development and generates multi-organ defects compatible with an Alagille syndrome phenocopy. Development 131, 5753-5766 (2004).
    • (2004) Development , vol.131 , pp. 5753-5766
    • Lorent, K.1    Yeo, S.-Y.2    Oda, T.3    Chandrasekharappa, S.4    Chitnis, A.5    Matthews, R.P.6    Pack, M.7
  • 19
    • 84863842159 scopus 로고    scopus 로고
    • Biliary atresia: Cellular dynamics and immune dysregulation
    • A. G. Feldman, C. L. Mack, Biliary atresia: Cellular dynamics and immune dysregulation. Semin. Pediatr. Surg. 21, 192-200 (2012).
    • (2012) Semin. Pediatr. Surg , vol.21 , pp. 192-200
    • Feldman, A.G.1    Mack, C.L.2
  • 20
    • 79551593467 scopus 로고    scopus 로고
    • Biliary atresia: Will blocking inflammation tame the disease?
    • K. Bessho, J. A. Bezerra, Biliary atresia: Will blocking inflammation tame the disease? Annu. Rev. Med. 62, 171-185 (2011).
    • (2011) Annu. Rev. Med , vol.62 , pp. 171-185
    • Bessho, K.1    Bezerra, J.A.2
  • 22
    • 68849092071 scopus 로고    scopus 로고
    • Neonatal NK cells target the mouse duct epithelium via Nkg2d and drive tissue-specific injury in experimental biliary atresia
    • P. Shivakumar, G. E. Sabla, P. Whitington, C. A. Chougnet, J. A. Bezerra, Neonatal NK cells target the mouse duct epithelium via Nkg2d and drive tissue-specific injury in experimental biliary atresia. J. Clin. Invest. 119, 2281-2290 (2009).
    • (2009) J. Clin. Invest , vol.119 , pp. 2281-2290
    • Shivakumar, P.1    Sabla, G.E.2    Whitington, P.3    Chougnet, C.A.4    Bezerra, J.A.5
  • 23
    • 84882586277 scopus 로고    scopus 로고
    • B cell deficient mice are protected from biliary obstruction in the rotavirus-induced mouse model of biliary atresia
    • A. G. Feldman, R. M. Tucker, E. K. Fenner, R. Pelanda, C. L. Mack, B cell deficient mice are protected from biliary obstruction in the rotavirus-induced mouse model of biliary atresia. PLOS One 8, e73644 (2013).
    • (2013) PLOS One , vol.8 , pp. e73644
    • Feldman, A.G.1    Tucker, R.M.2    Fenner, E.K.3    Pelanda, R.4    Mack, C.L.5
  • 24
    • 84863510145 scopus 로고    scopus 로고
    • Regulatory T cells control the CD8 adaptive immune response at the time of ductal obstruction in experimental biliary atresia
    • C. S. Lages, J. Simmons, C. A. Chougnet, A. G. Miethke, Regulatory T cells control the CD8 adaptive immune response at the time of ductal obstruction in experimental biliary atresia. Hepatology 56, 219-227 (2012).
    • (2012) Hepatology , vol.56 , pp. 219-227
    • Lages, C.S.1    Simmons, J.2    Chougnet, C.A.3    Miethke, A.G.4
  • 25
    • 84884418640 scopus 로고    scopus 로고
    • Regulatory T cells inhibit Th1 cellmediated bile duct injury in murine biliary atresia
    • R. M. Tucker, A. G. Feldman, E. K. Fenner, C. L. Mack, Regulatory T cells inhibit Th1 cellmediated bile duct injury in murine biliary atresia. J. Hepatol. 59, 790-796 (2013).
    • (2013) J. Hepatol , vol.59 , pp. 790-796
    • Tucker, R.M.1    Feldman, A.G.2    Fenner, E.K.3    Mack, C.L.4
  • 27
    • 80053265930 scopus 로고    scopus 로고
    • Dendritic cells regulate natural killer cell activation and epithelial injury in experimental biliary atresia
    • V. Saxena, P. Shivakumar, G. Sabla, R. Mourya, C. Chougnet, J. A. Bezerra, Dendritic cells regulate natural killer cell activation and epithelial injury in experimental biliary atresia. Sci. Transl. Med. 3, 102ra94 (2011).
    • (2011) Sci. Transl. Med , vol.3 , pp. 102ra94
    • Saxena, V.1    Shivakumar, P.2    Sabla, G.3    Mourya, R.4    Chougnet, C.5    Bezerra, J.A.6
  • 28
    • 0041694469 scopus 로고    scopus 로고
    • Development and maturation of the immune system in zebrafish, Danio rerio: A gene expression profiling, in situ hybridization and immunological study
    • S. H. Lam, H. L. Chua, Z. Gong, T. J. Lam, Y. M. Sin, Development and maturation of the immune system in zebrafish, Danio rerio: A gene expression profiling, in situ hybridization and immunological study. Dev. Comp. Immunol. 28, 9-28 (2004).
    • (2004) Dev. Comp. Immunol , vol.28 , pp. 9-28
    • Lam, S.H.1    Chua, H.L.2    Gong, Z.3    Lam, T.J.4    Sin, Y.M.5
  • 29
    • 80555126017 scopus 로고    scopus 로고
    • Zebrafish: Model for the study of inflammation and the innate immune response to infectious diseases
    • B. Novoa, A. Figueras, Zebrafish: Model for the study of inflammation and the innate immune response to infectious diseases. Adv. Exp. Med. Biol. 946, 253-275 (2012).
    • (2012) Adv. Exp. Med. Biol , vol.946 , pp. 253-275
    • Novoa, B.1    Figueras, A.2
  • 30
    • 79251537766 scopus 로고    scopus 로고
    • Mpeg1 promoter transgenes direct macrophage-lineage expression in zebrafish
    • F. Ellett, L. Pase, J. W. Hayman, A. Andrianopoulos, G. J. Lieschke, mpeg1 promoter transgenes direct macrophage-lineage expression in zebrafish. Blood 117, e49-e56 (2011).
    • (2011) Blood , vol.117 , pp. e49-e56
    • Ellett, F.1    Pase, L.2    Hayman, J.W.3    Andrianopoulos, A.4    Lieschke, G.J.5
  • 32
    • 77949543568 scopus 로고    scopus 로고
    • Macrophages are targeted by rotavirus in experimental biliary atresia and induce neutrophil chemotaxis by Mip2/Cxcl2
    • S. K. Mohanty, C. A. P. Ivantes, R. Mourya, C. Pacheco, J. A. Bezerra, Macrophages are targeted by rotavirus in experimental biliary atresia and induce neutrophil chemotaxis by Mip2/Cxcl2. Pediatr. Res. 67, 345-351 (2010).
    • (2010) Pediatr. Res , vol.67 , pp. 345-351
    • Mohanty, S.K.1    Ivantes, C.A.P.2    Mourya, R.3    Pacheco, C.4    Bezerra, J.A.5
  • 34
    • 84903182040 scopus 로고    scopus 로고
    • Gene expression signature for biliary atresia and a role for interleukin-8 in pathogenesis of experimental disease
    • K. Bessho, R. Mourya, P. Shivakumar, S. Walters, J. C. Magee, M. Rao, A. G. Jegga, J. A. Bezerra, Gene expression signature for biliary atresia and a role for interleukin-8 in pathogenesis of experimental disease. Hepatology 60, 211-223 (2014).
    • (2014) Hepatology , vol.60 , pp. 211-223
    • Bessho, K.1    Mourya, R.2    Shivakumar, P.3    Walters, S.4    Magee, J.C.5    Rao, M.6    Jegga, A.G.7    Bezerra, J.A.8
  • 35
    • 84883220413 scopus 로고    scopus 로고
    • The nitroreductase system of inducible targeted ablation facilitates cell-specific regenerative studies in zebrafish
    • D. T. White, J. S. Mumm, The nitroreductase system of inducible targeted ablation facilitates cell-specific regenerative studies in zebrafish. Methods 62, 232-240 (2013).
    • (2013) Methods , vol.62 , pp. 232-240
    • White, D.T.1    Mumm, J.S.2
  • 36
    • 77149154314 scopus 로고    scopus 로고
    • Reiterative use of the notch signal during zebrafish intrahepatic biliary development
    • K. Lorent, J. C. Moore, A. F. Siekmann, N. Lawson, M. Pack, Reiterative use of the notch signal during zebrafish intrahepatic biliary development. Dev. Dyn. 239, 855-864 (2010).
    • (2010) Dev. Dyn , vol.239 , pp. 855-864
    • Lorent, K.1    Moore, J.C.2    Siekmann, A.F.3    Lawson, N.4    Pack, M.5
  • 37
    • 82255181542 scopus 로고    scopus 로고
    • Association of X-prolyl aminopeptidase 1 rs17095355 polymorphism with biliary atresia in Thai children
    • S. Kaewkiattiyot, S. Honsawek, P. Vejchapipat, V. Chongsrisawat, Y. Poovorawan, Association of X-prolyl aminopeptidase 1 rs17095355 polymorphism with biliary atresia in Thai children. Hepatol. Res. 41, 1249-1252 (2011).
    • (2011) Hepatol. Res , vol.41 , pp. 1249-1252
    • Kaewkiattiyot, S.1    Honsawek, S.2    Vejchapipat, P.3    Chongsrisawat, V.4    Poovorawan, Y.5
  • 40
    • 84872082435 scopus 로고    scopus 로고
    • Regulation of multiple DNA repair pathways by the Fanconi anemia protein SLX4
    • Y. Kim, G. S. Spitz, U. Veturi, F. P. Lach, A. D. Auerbach, A. Smogorzewska, Regulation of multiple DNA repair pathways by the Fanconi anemia protein SLX4. Blood 121, 54-63 (2013).
    • (2013) Blood , vol.121 , pp. 54-63
    • Kim, Y.1    Spitz, G.S.2    Veturi, U.3    Lach, F.P.4    Auerbach, A.D.5    Smogorzewska, A.6
  • 43
    • 84860443311 scopus 로고    scopus 로고
    • Cholangiocyte cilia are abnormal in syndromic and nonsyndromic biliary atresia
    • A. S. Chu, P. A. Russo, R. G. Wells, Cholangiocyte cilia are abnormal in syndromic and nonsyndromic biliary atresia. Mod. Pathol. 25, 751-757 (2012).
    • (2012) Mod. Pathol , vol.25 , pp. 751-757
    • Chu, A.S.1    Russo, P.A.2    Wells, R.G.3
  • 46
    • 0036278213 scopus 로고    scopus 로고
    • Isolation of an anaerobic intestinal bacterium capable of cleaving the C-ring of the isoflavonoid daidzein
    • H. G. Hur, R. Beger, T. Heinze, J. Lay, J. Freeman, J. Dore, F. Rafii, Isolation of an anaerobic intestinal bacterium capable of cleaving the C-ring of the isoflavonoid daidzein. Arch. Microbiol. 178, 8-12 (2002).
    • (2002) Arch. Microbiol , vol.178 , pp. 8-12
    • Hur, H.G.1    Beger, R.2    Heinze, T.3    Lay, J.4    Freeman, J.5    Dore, J.6    Rafii, F.7
  • 48
    • 0029099538 scopus 로고
    • A urinary profile study of dietary phytoestrogens. The identification and mode of metabolism of new isoflavonoids
    • G. E. Joannou, G. E. Kelly, A. Y. Reeder, M. Waring, C. Nelson, A urinary profile study of dietary phytoestrogens. The identification and mode of metabolism of new isoflavonoids. J. Steroid Biochem. Mol. Biol. 54, 167-184 (1995).
    • (1995) J. Steroid Biochem. Mol. Biol , vol.54 , pp. 167-184
    • Joannou, G.E.1    Kelly, G.E.2    Reeder, A.Y.3    Waring, M.4    Nelson, C.5
  • 49
    • 58149293227 scopus 로고    scopus 로고
    • Bile duct ligation in neonatal rats: Is it a valid experimental model for biliary atresia studies?
    • N. E. M. Gibelli, U. Tannuri, E. S. de Mello, C. J. Rodrigues, Bile duct ligation in neonatal rats: Is it a valid experimental model for biliary atresia studies? Pediatr. Transplant. 13, 81-87 (2009).
    • (2009) Pediatr. Transplant , vol.13 , pp. 81-87
    • Gibelli, N.E.M.1    Tannuri, U.2    De Mello, E.S.3    Rodrigues, C.J.4
  • 50
    • 0001304425 scopus 로고
    • On congenital obliteration of the bile-ducts
    • J. Thomson, On congenital obliteration of the bile-ducts. Edinb. Med. J. 37, 523-531 (1892).
    • (1892) Edinb. Med. J , vol.37 , pp. 523-531
    • Thomson, J.1
  • 51
    • 84871712311 scopus 로고    scopus 로고
    • An integrin-ILK-microtubule network orients cell polarity and lumen formation in glandular epithelium
    • N. Akhtar, C. H. Streuli, An integrin-ILK-microtubule network orients cell polarity and lumen formation in glandular epithelium. Nat. Cell Biol. 15, 17-27 (2013).
    • (2013) Nat. Cell Biol , vol.15 , pp. 17-27
    • Akhtar, N.1    Streuli, C.H.2
  • 52
    • 84865262157 scopus 로고    scopus 로고
    • A1-and a5-containing laminins regulate the development of bile ducts via b1 integrin signals
    • N. Tanimizu, Y. Kikkawa, T. Mitaka, A. Miyajima, a1-and a5-containing laminins regulate the development of bile ducts via b1 integrin signals. J. Biol. Chem. 287, 28586-28597 (2012).
    • (2012) J. Biol. Chem , vol.287 , pp. 28586-28597
    • Tanimizu, N.1    Kikkawa, Y.2    Mitaka, T.3    Miyajima, A.4
  • 53
    • 84874620111 scopus 로고    scopus 로고
    • The PCP effector Fuzzy controls cilial assembly and signaling by recruiting Rab8 and Dishevelled to the primary cilium
    • Y. Zilber, S. Babayeva, J. H. Seo, J. J. Liu, S. Mootin, E. Torban, The PCP effector Fuzzy controls cilial assembly and signaling by recruiting Rab8 and Dishevelled to the primary cilium. Mol. Biol. Cell 24, 555-565 (2013).
    • (2013) Mol. Biol. Cell , vol.24 , pp. 555-565
    • Zilber, Y.1    Babayeva, S.2    Seo, J.H.3    Liu, J.J.4    Mootin, S.5    Torban, E.6
  • 55
    • 84858073877 scopus 로고    scopus 로고
    • Nuclear localization of Prickle2 is required to establish cell polarity during early mouse embryogenesis
    • H. Tao, K.-I. Inoue, H. Kiyonari, A. G. Bassuk, J. D. Axelrod, H. Sasaki, S. Aizawa, N. Ueno, Nuclear localization of Prickle2 is required to establish cell polarity during early mouse embryogenesis. Dev. Biol. 364, 138-148 (2012).
    • (2012) Dev. Biol , vol.364 , pp. 138-148
    • Tao, H.1    Inoue, K.-I.2    Kiyonari, H.3    Bassuk, A.G.4    Axelrod, J.D.5    Sasaki, H.6    Aizawa, S.7    Ueno, N.8
  • 56
    • 79951676868 scopus 로고    scopus 로고
    • Disruption of planar cell polarity activity leads to developmental biliary defects
    • S. Cui, L. M. Capecci, R. P. Matthews, Disruption of planar cell polarity activity leads to developmental biliary defects. Dev. Biol. 351, 229-241 (2011).
    • (2011) Dev. Biol , vol.351 , pp. 229-241
    • Cui, S.1    Capecci, L.M.2    Matthews, R.P.3
  • 57
    • 1842427830 scopus 로고    scopus 로고
    • The evolutionary dynamics of eukaryotic gene order
    • L. D. Hurst, C. Pál, M. J. Lercher, The evolutionary dynamics of eukaryotic gene order. Nat. Rev. Genet. 5, 299-310 (2004).
    • (2004) Nat. Rev. Genet , vol.5 , pp. 299-310
    • Hurst, L.D.1    Pál, C.2    Lercher, M.J.3
  • 58
    • 84856406204 scopus 로고    scopus 로고
    • Coexpression of linked gene pairs persists long after their separation
    • G.-Z. Wang, W.-H. Chen, M. J. Lercher, Coexpression of linked gene pairs persists long after their separation. Genome Biol. Evol. 3, 565-570 (2011).
    • (2011) Genome Biol. Evol , vol.3 , pp. 565-570
    • Wang, G.-Z.1    Chen, W.-H.2    Lercher, M.J.3
  • 60
    • 33646729244 scopus 로고    scopus 로고
    • Intermingling of chromosome territories in interphase suggests role in translocations and transcription-dependent associations
    • M. R. Branco, A. Pombo, Intermingling of chromosome territories in interphase suggests role in translocations and transcription-dependent associations. PLOS Biol. 4, e138 (2006).
    • (2006) PLOS Biol , vol.4 , pp. e138
    • Branco, M.R.1    Pombo, A.2
  • 61
    • 84883484694 scopus 로고    scopus 로고
    • Chromatin and epigenetic features of long-range gene regulation
    • N. Harmston, B. Lenhard, Chromatin and epigenetic features of long-range gene regulation. Nucleic Acids Res. 41, 7185-7199 (2013).
    • (2013) Nucleic Acids Res , vol.41 , pp. 7185-7199
    • Harmston, N.1    Lenhard, B.2
  • 62
    • 84865070200 scopus 로고    scopus 로고
    • Comparing enhancer action in cis and in trans
    • J. R. Bateman, J. E. Johnson, M. N. Locke, Comparing enhancer action in cis and in trans. Genetics 191, 1143-1155 (2012).
    • (2012) Genetics , vol.191 , pp. 1143-1155
    • Bateman, J.R.1    Johnson, J.E.2    Locke, M.N.3
  • 64
    • 84856768815 scopus 로고    scopus 로고
    • Smooth muscle caldesmon modulates peristalsis in the wild type and non-innervated zebrafish intestine
    • J. Abrams, G. Davuluri, C. Seiler, M. Pack, Smooth muscle caldesmon modulates peristalsis in the wild type and non-innervated zebrafish intestine. Neurogastroenterol. Motil. 24, 288-299 (2012).
    • (2012) Neurogastroenterol. Motil , vol.24 , pp. 288-299
    • Abrams, J.1    Davuluri, G.2    Seiler, C.3    Pack, M.4
  • 70
    • 0348013129 scopus 로고    scopus 로고
    • Evaluation of differential gene expression by microarray analysis in small and large cholangiocytes isolated from normal mice
    • Y. Ueno, G. Alpini, K. Yahagi, N. Kanno, Y. Moritoki, K. Fukushima, S. Glaser, G. LeSage, T. Shimosegawa, Evaluation of differential gene expression by microarray analysis in small and large cholangiocytes isolated from normal mice. Liver Int. 23, 449-459 (2003).
    • (2003) Liver Int , vol.23 , pp. 449-459
    • Ueno, Y.1    Alpini, G.2    Yahagi, K.3    Kanno, N.4    Moritoki, Y.5    Fukushima, K.6    Glaser, S.7    Lesage, G.8    Shimosegawa, T.9
  • 71
    • 84902107245 scopus 로고    scopus 로고
    • Isolation of neonatal extrahepatic cholangiocytes
    • S. Karjoo, R. G. Wells, Isolation of neonatal extrahepatic cholangiocytes. J. Vis. Exp. e51621 (2014).
    • (2014) J. Vis. Exp. , pp. e51621
    • Karjoo, S.1    Wells, R.G.2
  • 72
    • 84878235678 scopus 로고    scopus 로고
    • Hepatic stellate cells and portal fibroblasts are the major cellular sources of collagens and lysyl oxidases in normal liver and early after injury
    • M. Perepelyuk, M. Terajima, A.Y. Wang, P. C. Georges, P. A. Janmey, M. Yamauchi, R. G. Wells, Hepatic stellate cells and portal fibroblasts are the major cellular sources of collagens and lysyl oxidases in normal liver and early after injury. Am. J. Physiol. Gastrointest. Liver Physiol. 304, G605-G614 (2013).
    • (2013) Am. J. Physiol. Gastrointest. Liver Physiol , vol.304 , pp. G605-G614
    • Perepelyuk, M.1    Terajima, M.2    Wang, A.Y.3    Georges, P.C.4    Janmey, P.A.5    Yamauchi, M.6    Wells, R.G.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.